Chronic Neck PainNCT07241312
Relationship Between Muscle Oxygenation and Upper Extremity Exercise Capacity in Patients With Chronic Neck Pain
An observational study of Chronic Neck Pain, run by Kirsehir Ahi Evran Universitesi at 1 site in Turkey (Türkiye).
Trial summary
The aim of the study was to investigate the relationship between upper extremity exercise capacity and muscle oxygenation, muscle strength, and activities of daily living in patients with chronic neck pain. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Chronic Neck Pain
- How many people
- 51 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 24 Nov 2025to 10 Jan 2026
- How long will I take part?
- 2 Days
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients between the ages of 18-65 who have had neck pain for at least 12 weeks, who were followed up in the Physical Therapy Outpatient Clinic of the Department of Physical Medicine and Rehabilitation will be included in the study.
Who may be able to join
- Patients with neck pain lasting at least 3 months due to one of the following problems: cervical strain or sprain, cervical disc lesions, cervical spondylosis, facet joint dysfunction, and myofascial pain syndrome.
Who cannot join
- Neck pain intensity during activity is below 3 points according to the Visual Analog Scale
- Upper extremity motor deficit on neurological examination
- Any surgery related to neck problems
- Cervical radiculopathy
- Any upper extremity surgery
- Any rheumatic and/or neurological disease or any disease affecting the vestibular system
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Kırşehir Ahi Evran University, Physical Therapy and Rehabilitation Center, Cardiopulmonary Unit
Kırşehir
About this study
Official title: Investigation of the Relationship Between Muscle Oxygenation and Upper Extremity Exercise Capacity, Respiratory and Peripheral Muscle Strength, and Activities of Daily Living in Patients With Chronic Neck Pain
The aim of the study was to investigate the relationship between upper extremity exercise capacity and muscle oxygenation, muscle strength, and activities of daily living in patients with chronic neck pain.
Read the detailed description
Neck pain is an important public health problem that causes disability worldwide Chronic neck pain is defined as the presence of pain in an individual's neck area for more than twelve weeks. Chronic neck pain negatively affects the daily living activities of the individual; functional limitation causes job loss.
Neck pain has been observed to be associated with the trapezius muscle and impaired microcirculation in the trapezius muscle and inadequate muscle blood flow and oxygenation.
In addition, neck pain has been stated to reduce upper extremity performance. However, most of the results regarding the relationship between muscle activity and pain are not consistent. In addition, there are studies showing that respiratory muscles as well as peripheral muscles are affected in these patients. In the light of all this information, it was concluded that there may be a relationship between upper extremity exercise capacity and the oxygen level of the trapezius muscle and activities of daily living in patients with chronic neck pain. In this context, the aim of the study was to investigate the relationship between upper extremity exercise capacity and muscle oxygenation, muscle strength and activities of daily living in patients with chronic neck pain.
- Conditions
- Chronic Neck Pain
- Keywords
- chronic neck pain, upper extremity, muscle oxygenation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Chronic Neck Pain Group | Individuals between the ages of 18-65 who have had neck pain for at least 12 weeks, who were followed up in the Physical Therapy Outpatient Clinic of the Department of Physical Medicine and Rehabilitation will be included in the study. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Evaluation of Trapezius Muscle Oxygen Saturation
Patients' trapezius muscle oxygen saturation will be measured using a near infrared spectroscopy (Moxy® monitor (Moxy, Fortiori Design LLC, Minnesota, USA)).
Measured: Day 1
Evaluation of upper extremity capacity
Patients' upper extremity functional exercise capacity will be evaluated with six-minute pegboard and ring test.
Measured: Day 1
Secondary outcomes (4)
Evaluation of peripheral muscle strength
Patients' shoulder abductor and shoulder flexor, elbow flexor and upper trapezius muscle strength will be evaluated with a portable hand dynamometer (KFORCE Muscle Controller®, KinventTM, France).
Measured: Day 2
Evaluation of respiratory muscle strength
An electronic mouth pressure device in accordance with American Thoracic Society and European Respiratory Society criteria will be used to evaluate respiratory muscle strength (Micro Medical MicroRM, UK).
Measured: Day 2
Evaluation of activity of daily living
The Glittre activity of daily living test will be used to evaluate patients' activities of daily living.
Measured: Day 2
Evaluation of upper extremity functional status
Upper Extremity Functional Index will be used to evaluate the upper extremity functional status of the patients.
Measured: Day 1
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Nov 2025
- Study start24 Nov 2025
- Primary completion30 Dec 2025
- Study completion10 Jan 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic Neck PainStudies of the same condition, open and under way.
- More trials run by Kirsehir Ahi Evran UniversitesiThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 51 participants (actual)
- Target duration
- 2 Days
Sponsor and investigators
- Lead sponsor
- Kirsehir Ahi Evran Universitesi
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Başak KAVALCI KOL, Kirsehir Ahi Evran Universitesi
- Investigators
- Başak KAVALCI KOL, PhD, Principal investigator, Kirsehir Ahi Evran Universitesi
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07241312
- Sponsor's protocol ID
- AhiEvranU530
- Status last verified
- Nov 2025
- First submitted
- 17 Nov 2025
- Last updated
- 3 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Relationship Between Muscle Oxygenation and Upper Extremity Exercise Capacity, Respiratory and Peripheral Muscle Strength, and Activities of Daily Living in Patients With Chronic Neck Pain
- ClinicalTrials.gov ID
- NCT07241312
- Acronym / sponsor ID
- AhiEvranU530
- Conditions
- Chronic Neck Pain
- Keywords
- chronic neck pain, upper extremity, muscle oxygenation
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 51 participants (actual)
- Lead sponsor
- Kirsehir Ahi Evran UniversitesiUniversity, hospital or other
- Study start
- 24 Nov 2025 (actual)
- Primary completion
- 30 Dec 2025 (actual)
- Study completion
- 10 Jan 2026 (actual)
- First posted
- 21 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of the study was to investigate the relationship between upper extremity exercise capacity and muscle oxygenation, muscle strength, and activities of daily living in patients with chronic neck pain.
Detailed description
Neck pain is an important public health problem that causes disability worldwide Chronic neck pain is defined as the presence of pain in an individual's neck area for more than twelve weeks. Chronic neck pain negatively affects the daily living activities of the individual; functional limitation causes job loss.
Neck pain has been observed to be associated with the trapezius muscle and impaired microcirculation in the trapezius muscle and inadequate muscle blood flow and oxygenation.
In addition, neck pain has been stated to reduce upper extremity performance. However, most of the results regarding the relationship between muscle activity and pain are not consistent. In addition, there are studies showing that respiratory muscles as well as peripheral muscles are affected in these patients. In the light of all this information, it was concluded that there may be a relationship between upper extremity exercise capacity and the oxygen level of the trapezius muscle and activities of daily living in patients with chronic neck pain. In this context, the aim of the study was to investigate the relationship between upper extremity exercise capacity and muscle oxygenation, muscle strength and activities of daily living in patients with chronic neck pain.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 2 Days
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Chronic Neck Pain Group | – | –Individuals between the ages of 18-65 who have had neck pain for at least 12 weeks, who were followed up in the Physical Therapy Outpatient Clinic of the Department of Physical Medicine and Rehabilitation will be included in the study. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients between the ages of 18-65 who have had neck pain for at least 12 weeks, who were followed up in the Physical Therapy Outpatient Clinic of the Department of Physical Medicine and Rehabilitation will be included in the study.
Key inclusion criteria (1 listed)
- Patients with neck pain lasting at least 3 months due to one of the following problems: cervical strain or sprain, cervical disc lesions, cervical spondylosis, facet joint dysfunction, and myofascial pain syndrome.
Key exclusion criteria (6 listed)
- Neck pain intensity during activity is below 3 points according to the Visual Analog Scale
- Upper extremity motor deficit on neurological examination
- Any surgery related to neck problems
- Cervical radiculopathy
- Any upper extremity surgery
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Evaluation of Trapezius Muscle Oxygen Saturation
Time frame: Day 1
Patients' trapezius muscle oxygen saturation will be measured using a near infrared spectroscopy (Moxy® monitor (Moxy, Fortiori Design LLC, Minnesota, USA)).
Evaluation of upper extremity capacity
Time frame: Day 1
Patients' upper extremity functional exercise capacity will be evaluated with six-minute pegboard and ring test.
4 secondary outcomes
Evaluation of peripheral muscle strength
Time frame: Day 2
Evaluation of respiratory muscle strength
Time frame: Day 2
Evaluation of activity of daily living
Time frame: Day 2
Evaluation of upper extremity functional status
Time frame: Day 1
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Feb 2026.
- Individual participant dataSharing planned: No
Related trials for Chronic Neck Pain
Not yet recruiting
Comparison of the Effectiveness of Motor Imagery Exercises and Suboccipital Myofascial Release Techniques in Nonspecific Chronic Neck Pain
Non-specific Chronic Neck Pain
Not yet recruiting
Digital Use, 24-Hour Movement Behaviors, and Myofascial Release in University Students With Neck Pain
Forward Head Posture, Chronic Nonspecific Neck Pain
Active, not recruiting
Cervical Stabilization vs Scapular Clock Exercises for Chronic Non-Specific Neck Pain
Chronic Non-Specific Neck Pain
Not yet recruitingObservational study
Agreement Between CSI and IASP Pain Classification in Chronic Cervical Myofascial Pain
Myofascial Pain Syndrome - Neck
RecruitingObservational study
Upper Extremity Exercise Capacity in Chronic Non-specific Neck Pain
Neck Pain
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Başak KAVALCI KOL, PhD principal investigator
Kirsehir Ahi Evran Universitesi
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Chronic Neck Pain, run by Kirsehir Ahi Evran Universitesi at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 3 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Evaluation of Trapezius Muscle Oxygen Saturation (time frame: Day 1). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Feb 2026.