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Non-specific Chronic Neck PainMI-SMR-NSCNPNCT07883915

Comparison of the Effectiveness of Motor Imagery Exercises and Suboccipital Myofascial Release Techniques in Nonspecific Chronic Neck Pain

A study testing Active Exercise, Motor Imagery and Suboccipital Myofascial Release in people with Non-specific Chronic Neck Pain, run by Ankara Yildirim Beyazıt University at 1 site in Turkey (Türkiye).

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Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

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Official record

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Trial summary

The aim of this three-group randomized controlled study is to investigate the effectiveness of MI and SMR interventions on pain, proprioception, quality of life, disability, and ROM parameters in individuals aged 18-50 with NSCNP. Read more about this study

Who is it for?
Ages 18 to 50 years
Conditions the study is for
Non-specific Chronic Neck Pain
What is being tested?
Active Exercise, Motor Imagery and Suboccipital Myofascial Release
Could I receive a placebo?
No, everyone receives an active treatment
How many people
51 participants
Where
1 siteTurkey (Türkiye)
Study dates
Nov 2026to Apr 2028
Phase
Interventional

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 50 years
  • All sexes
  • No healthy volunteers
  • Adult

Who may be able to join

  • Having an MIQ-3 score that is at most two standard deviations above or below the mean,
  • Having a Dizziness Handicap Inventory score below 20,
  • Having a diagnosis of NSCNP

Who cannot join

  • Wiplash,
  • Pregnancy,
  • Neoplasia,
  • Infectious or inflammatory disorders,
  • Specific neck pain resulting from traumatic events involving bone fractures or neck injuries,
  • Osteoarthritic changes,
Show all 11Show fewer
  • Positive neurological signs or evidence of spinal compression,
  • Neck pain associated with vertigo,
  • Cervical surgeries,
  • Acute headache,
  • Headaches occurring prior to the onset of neck pain and headaches of non-cervical origin

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Ayça ŞİRİN, Master of Science contact

+90 545 410 59 00

ayca41sirin@gmail.com

Turkey (Türkiye)1 site
  • Ankara Bilkent City Hospital Physical Medicine and Rehabilitation Hospital

    Ankara, Çankaya

Other trials in Turkey (Türkiye)

About this study

Official title: Comparison of the Effectiveness of Motor Imagery Exercises and Suboccipital Myofascial Release Techniques on Pain, Proprioception, and Kinesiophobia in Nonspecific Chronic Neck Pain

The aim of this three-group randomized controlled study is to investigate the effectiveness of MI and SMR interventions on pain, proprioception, quality of life, disability, and ROM parameters in individuals aged 18-50 with NSCNP.

The primary research questions it seeks to answer are as follows:

Do MI exercises, when applied in addition to active exercise, lead to changes in pain, proprioception, and kinesiophobia in individuals with NSCNP? Does the suboccipital myofascial release technique, when applied in addition to active exercise, lead to changes in pain, proprioception, and kinesiophobia in individuals with NSCNP? Participants will be randomly assigned to one of three groups to compare the MI and SMR techniques.

Read the detailed description

Proprioception is considered a crucial element in the seamless execution of pain-free movement. In cases of chronic pain, proprioceptive ability is compromised due to altered sensorimotor control at various levels of pain transmission. Motor imagery (MI) is utilized to enhance motor performance and facilitate the learning of motor tasks, while suboccipital myofascial release (SMR) improves neck-related disability and overall pain. However, evidence regarding the efficacy of MI and SMR techniques in the management of non-specific neck pain (NSCNP) remains limited.

The aim of this study is to compare the efficacy of MI exercises and the SMR technique in the management of NSCNP through a multifaceted evaluation, and to expand the range of effective, sustainable, and accessible conservative treatment alternatives. A dual inclinometer, goniometer, and algometer will be employed in the study. Participants will undergo assessments including proprioception, pressure pain threshold, and neck range of motion (ROM).

The data obtained will shed light on the efficacy of these interventions regarding parameters such as pain intensity, disability, and kinesiophobia, potentially serving as foundational data for the future development of diagnostic, therapeutic, and clinical processes in this field.

Being tested
Active Exercise, Motor Imagery, Suboccipital Myofascial Release
Keywords
nscnp, proprioception, pain management, motor imagery, suboccipital myofascial release
Medical subject headings
Agnosia

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Active ExerciseOther

    Active exercises will consist of four cervical movements involving the maintenance of craniocervical flexion, and all of these exercises will be performed in a single session. The program will continue for six weeks.

  • Motor ImageryOther

    Motor imagery exercises are structured in three stages. First stage: performing a guided mental task Second stage: internal visual imagery Third stage: external visual imagery The program will last for six weeks.

  • Suboccipital Myofascial ReleaseOther

    It will be performed by the therapist while the participant is in the supine position. The therapist will apply pressure to the suboccipital region until a reduction in muscle tone is detected.

    The procedure will be continued for six weeks.

Study groups in NCT07883915
Study groupRoleWhat they receive
Group 1: Control / Active Exercise GroupActive comparatorAn active exercise program will be implemented.
Receives: Other: Active Exercise
Group 2: Active Exercise + Motor Imagery GroupExperimentalIn addition to active exercise, motor imagery exercises will be administered.
Receives: Other: Active Exercise; Other: Motor Imagery
Group 2: Active Exercise + Suboccipital Myofascial Release GroupExperimentalIn addition to active exercise, the suboccipital myofascial release technique will be applied.
Receives: Other: Active Exercise; Other: Suboccipital Myofascial Release

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Proprioception

    Measurement will be performed using a dual inclinometer. Joint position sense error will be evaluated.

    Measured: baseline, six weeks

  2. Pain Pressure Threshold

    The pressure pain threshold will be assessed using an algometer.

    Measured: baseline, six weeks

  3. Range of Motion (ROM)

    ROM will be assessed using a goniometer.

    Measured: baseline, six weeks

Secondary outcomes (4)
  1. Tampa Scale of Kinesiophobia for Kinesiophobia

    Measured: baseline, six weeks

  2. SF-36 for Quality of Life

    Measured: baseline, six weeks

  3. Copenhagen Neck Functional Disability Scale for Neck Disability

    Measured: baseline, six weeks

  4. Short-form McGill Pain Questionnaire for Pain Intensity

    Measured: baseline, six weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted20 Oct 2026
  2. Study startNov 2026 (estimated)
  3. Primary completionJan 2028 (estimated)
  4. Study completionApr 2028 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Other
Allocation
Randomised
Intervention model
Parallel groups
Masking
None (open label)
Enrolment
51 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07883915
Sponsor's protocol ID
AnkaraYBU_NSCNP
Acronym
MI-SMR-NSCNP
Status last verified
Oct 2026
First submitted
14 Oct 2026
Last updated
20 Oct 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

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