Hematological CancerNCT07251348
Progressive Relaxation and Psychoeducation in Patients With Hematological Malignancies
A study testing Muscle Relaxation and psychoeducation or Atomoxetine or stimulants according to ADHD severity in people with Hematological Cancer, run by Necmettin Erbakan University at 1 site in Turkey (Türkiye).
Trial summary
This study will be conducted to determine the effect of progressive relaxation and psychoeducation on perceived stress and hope in patients with hematological malignancies Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Hematological Cancer
- What is being tested?
- Muscle Relaxation and psychoeducation or Atomoxetine or stimulants according to ADHD severity
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 75 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Feb 2026to 30 Nov 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- 18 years of age or older
- Diagnosis of hematologic malignancy
- Ability to read and write
- Volunteer to participate in the study
Who cannot join
- Dementia and/or organic mental disorder
- Sensory loss related to vision and hearing
- Communication barrier
- Physical disability
- Respiratory distress
- Bone marrow transplant procedure
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Seydişehir Kamil Akkanat Sağlik Bilimleri Fakültesi
Konya, Seydi̇şehi̇r, 42000
About this study
Official title: The Effect of Progressive Relaxation and Psychoeducation on Perceived Stress and Hope in Patients With Hematologic Malignancies: A Non-Randomized Study
This study will be conducted to determine the effect of progressive relaxation and psychoeducation on perceived stress and hope in patients with hematological malignancies
Read the detailed description
Being healthy requires being in a state of complete physical and mental well-being. Therefore, mental and physical well-being must be maintained together. While each individual already has different stressors, the fact that hematological malignancies are chronic and immune-mediated diseases increases the stress factors perceived by individuals, and the difficulty and uncertainty of the process reduces their level of hope. This triggers the use of ineffective coping methods. Patients with high perceived stress levels and declining hope levels are unable to adequately manage the disease process. Consequently, mortality and morbidity rates increase. This experimentally planned study will be conducted between February 2026 and November 2026 at the Adult Inpatient Hematology Clinic of Gazi University Faculty of Medicine Hospital. The study will involve 75 individuals hospitalized at the clinic who meet the inclusion criteria. It is a non-randomized study with 2 intervention groups and 1 control group. Intervention group A (progressive relaxation group, n=25), intervention group B (psychoeducation, n=25), and control group (routine care, n=25). Patients in intervention group A will undergo a 3-week, 6-session progressive relaxation exercise program, conducted individually and face-to-face. Intervention Group B will receive a 3-week, 6-session, individual, face-to-face psychoeducation program. The control group will receive 3 weeks of routine nursing care identical to that provided to the other groups. In this study, which will include pre- and post-tests, data will be collected face-to-face using the perceived stress level scale and the Herth hope index scale. The primary objective of this study is to examine the effects of progressive relaxation and psychoeducation interventions on perceived stress and hope levels in patients with hematological malignancies.
- Conditions
- Hematological Cancer
- Being tested
- Muscle Relaxation, psychoeducation or Atomoxetine or stimulants according to ADHD severity
- Keywords
- hematologic malignancy, progressive relaxation, psychoeducation, stress, hope
- Medical subject headings
- Hematologic Neoplasms
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Muscle RelaxationBehavioural
Progressive relaxation is a relaxation technique based on tensing and relaxing muscles in sequence. The goal is to achieve physical and mental relaxation by feeling the difference between tension and relaxation. It is frequently used for stress, anxiety, sleep problems, and psychosomatic disorders. When practiced regularly, it increases a person's ability to relax and contributes to their overall well-being.
- Teaching progressive relaxation exercises to individuals diagnosed with cancer and supporting psychological well-being by reducing stress levels and increasing hope levels through these exercises (emotional gain)
- Reducing muscle tension and providing physical relaxation (psychomotor gain)
- To reduce stress and anxiety (emotional gain)
- To increase body awareness (emotional gain)
- To teach mental and physical relaxation (psychomotor gain)
- To provide emotional relief (emotional gain)
- To develop self-relaxation skills (psychomotor gain)
psychoeducation or Atomoxetine or stimulants according to ADHD severityBehavioural
Psychoeducation is a structured educational process that provides individuals with information about mental illnesses, ways to cope with stress, and healthy living skills. The goal is to help the person understand their illness and symptoms, learn coping methods, and increase their compliance with treatment. It has both an informative and a supportive aspect.
INTERVENTION B (PSYCHOEDUCATION) GROUP APPLICATION:
- A total of 6 sessions will be held with patients in intervention group B, twice a week for 3 weeks.
- Each session will last an average of 45 minutes.
- The 'Perceived Stress Level' scale and the 'Herth Hope Index' scale will be administered after the first session.
- The 'Perceived Stress Level' scale and the 'Herth Hope Index' scale will be administered after the final session.
| Study group | Role | What they receive |
|---|---|---|
| Progressive relaxation | Active comparator | Progressive relaxation; n=25: After the pre-test, 6 sessions (2 sessions per week) were planned for 3 weeks for individuals in this group. Each session will be conducted individually with patients, face-to-face, and will last 40-45 minutes. The post-test was administered after 3 weeks.
PROGRESSIVE RELAXATION SESSION TITLES:
1. SESSION: Introduction, Establishing Trust and the Concept of Relaxation
2. SESSION: Coping with a Cancer Diagnosis \& Introduction to the Progressive Relaxation Technique
3. SESSION: Progressive Muscle Relaxation Application - Upper Body3
4. SESSION: Progressive Muscle Relaxation - Lower Body
5. SESSION: Whole Body Relaxation - Reinforcing the Application
6. SESSION: Integrating Progressive Relaxation into Daily Life \& Closing Receives: Behavioral: Muscle Relaxation |
| psychoeducation | Active comparator | psychoeducation; n=25: After the pre-test, 6 sessions (2 sessions per week) were planned for 3 weeks for the individuals in this group. Each session will be conducted individually with patients, face-to-face, and will last 40-45 minutes. A post-test was administered after 3 weeks. Four expert opinions were obtained regarding the content.
PSYCHOEDUCATION SESSION TITLES:
1. SESSION: INTRODUCTION AND PROGRAM OVERVIEW 2nd SESSION: UNDERSTANDING THE DISEASE - EMPOWERING THROUGH KNOWLEDGE 3rd SESSION: IDENTIFYING PERCEIVED STRESS AND ITS EFFECTS 4. SESSION: COPING WITH STRESS AND INTRODUCTION TO HOPE 5. SESSION: UNDERSTANDING AND STRENGTHENING HOPE 6. SESSION: INTERNALIZING WHAT HAS BEEN LEARNED, MAINTAINING AND EVALUATING Receives: Behavioral: psychoeducation or Atomoxetine or stimulants according to ADHD severity |
| routine nursing care | No intervention | routine nursig care; n=25 No intervention was performed after the pre-test; routine nursing care was administered. The post-test was administered after 3 weeks. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Herth hope index level scale
Herth Hope Index: Developed by Kaye Herth (1992), its validity and reliability in Turkish were studied by Aslan and colleagues (2007). The scale consists of a total of 12 items: "Future" (questions 1, 2, 6, 11), "Positive readiness and expectation" (questions 4, 7, 10, 12), and "Connections with oneself and others" (questions 3, 5, 8, 9).
Measured: 9 months
perceived stress level scales
PERCEIVED STRESS SCALE: The adaptation of the perceived stress scale developed by Cohen, Kamarck, and Mermelsten (1983) into Turkish was carried out by Eskin et al. (2013). The perceived stress scale, consisting of a total of 14 items, aims to measure how stressful individuals perceive their life situations to be..
Measured: 9 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Nov 2025
- Study start1 Feb 2026
- Primary completion30 Nov 2026 (estimated)
- Study completion30 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Hematological CancerStudies of the same condition, open and under way.
- More trials run by Necmettin Erbakan UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Non-randomised
- Intervention model
- Sequential
- Model description
- Progressive relaxation group; n=25: After the pre-test, 6 sessions (2 sessions per week) were planned for 3 weeks for individuals in this group. Each session will be conducted individually with patients, face-to-face, and will last 40-45 minutes. The post-test was administered after 3 weeks. psychoeducation group; n=25: After the pre-test, 6 sessions (2 sessions per week) were planned for 3 weeks for the individuals in this group. Each session will be conducted individually with patients, face-to-face, and will last 40-45 minutes. A post-test was administered after 3 weeks. Four expert opinions were obtained regarding the content. routine nursing care group: no intervention n=25: The 'Perceived Stress Level' scale and the 'Herth Hope Index' scale will be administered after the initial interview. Routine nursing care was provided.After 3 weeks, the 'Perceived Stress Level' scale and the 'Herth Hope Index' scale will be administered after the
- Masking
- None (open label)
- Enrolment
- 75 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Necmettin Erbakan University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Tuba KORKMAZ ASLAN, Necmettin Erbakan University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07251348
- Sponsor's protocol ID
- NEÜ-SBF-TKA-02
- Status last verified
- May 2026
- First submitted
- 11 Sep 2025
- Last updated
- 15 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Progressive Relaxation and Psychoeducation on Perceived Stress and Hope in Patients With Hematologic Malignancies: A Non-Randomized Study
- ClinicalTrials.gov ID
- NCT07251348
- Acronym / sponsor ID
- NEÜ-SBF-TKA-02
- Conditions
- Hematological Cancer
- Keywords
- hematologic malignancy, progressive relaxation, psychoeducation, stress, hope
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 75 participants (estimated)
- Lead sponsor
- Necmettin Erbakan UniversityUniversity, hospital or other
- Study start
- 1 Feb 2026 (actual)
- Primary completion
- 30 Nov 2026 (estimated)
- Study completion
- 30 Nov 2026 (estimated)
- First posted
- 26 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will be conducted to determine the effect of progressive relaxation and psychoeducation on perceived stress and hope in patients with hematological malignancies
Detailed description
Being healthy requires being in a state of complete physical and mental well-being. Therefore, mental and physical well-being must be maintained together. While each individual already has different stressors, the fact that hematological malignancies are chronic and immune-mediated diseases increases the stress factors perceived by individuals, and the difficulty and uncertainty of the process reduces their level of hope. This triggers the use of ineffective coping methods. Patients with high perceived stress levels and declining hope levels are unable to adequately manage the disease process. Consequently, mortality and morbidity rates increase. This experimentally planned study will be conducted between February 2026 and November 2026 at the Adult Inpatient Hematology Clinic of Gazi University Faculty of Medicine Hospital. The study will involve 75 individuals hospitalized at the clinic who meet the inclusion criteria. It is a non-randomized study with 2 intervention groups and 1 control group. Intervention group A (progressive relaxation group, n=25), intervention group B (psychoeducation, n=25), and control group (routine care, n=25). Patients in intervention group A will undergo a 3-week, 6-session progressive relaxation exercise program, conducted individually and face-to-face. Intervention Group B will receive a 3-week, 6-session, individual, face-to-face psychoeducation program. The control group will receive 3 weeks of routine nursing care identical to that provided to the other groups. In this study, which will include pre- and post-tests, data will be collected face-to-face using the perceived stress level scale and the Herth hope index scale. The primary objective of this study is to examine the effects of progressive relaxation and psychoeducation interventions on perceived stress and hope levels in patients with hematological malignancies.
Study design
- Primary purpose
- Supportive care
- Allocation
- Non-randomised
- Intervention model
- Sequential
- Masking
- None (open label)
- Number of arms
- 3
- Model description
- Progressive relaxation group; n=25: After the pre-test, 6 sessions (2 sessions per week) were planned for 3 weeks for individuals in this group. Each session will be conducted individually with patients, face-to-face, and will last 40-45 minutes. The post-test was administered after 3 weeks. psychoeducation group; n=25: After the pre-test, 6 sessions (2 sessions per week) were planned for 3 weeks for the individuals in this group. Each session will be conducted individually with patients, face-to-face, and will last 40-45 minutes. A post-test was administered after 3 weeks. Four expert opinions were obtained regarding the content. routine nursing care group: no intervention n=25: The 'Perceived Stress Level' scale and the 'Herth Hope Index' scale will be administered after the initial interview. Routine nursing care was provided.After 3 weeks, the 'Perceived Stress Level' scale and the 'Herth Hope Index' scale will be administered after the
| Arm | Type | Receives |
|---|---|---|
| Progressive relaxation | Active comparator | Behavioral: Muscle RelaxationProgressive relaxation; n=25: After the pre-test, 6 sessions (2 sessions per week) were planned for 3 weeks for individuals in this group. Each session will be conducted individually with patients, face-to-face, and will last 40-45 minutes. The post-test was administered after 3 weeks. PROGRESSIVE RELAXATION SESSION TITLES: 1. SESSION: Introduction, Establishing Trust and the Concept of Relaxation 2. SESSION: Coping with a Cancer Diagnosis \& Introduction to the Progressive Relaxation Technique 3. SESSION: Progressive Muscle Relaxation Application - Upper Body3 4. SESSION: Progressive Muscle Relaxation - Lower Body 5. SESSION: Whole Body Relaxation - Reinforcing the Application 6. SESSION: Integrating Progressive Relaxation into Daily Life \& Closing |
| psychoeducation | Active comparator | Behavioral: psychoeducation or Atomoxetine or stimulants according to ADHD severitypsychoeducation; n=25: After the pre-test, 6 sessions (2 sessions per week) were planned for 3 weeks for the individuals in this group. Each session will be conducted individually with patients, face-to-face, and will last 40-45 minutes. A post-test was administered after 3 weeks. Four expert opinions were obtained regarding the content. PSYCHOEDUCATION SESSION TITLES: 1. SESSION: INTRODUCTION AND PROGRAM OVERVIEW 2nd SESSION: UNDERSTANDING THE DISEASE - EMPOWERING THROUGH KNOWLEDGE 3rd SESSION: IDENTIFYING PERCEIVED STRESS AND ITS EFFECTS 4. SESSION: COPING WITH STRESS AND INTRODUCTION TO HOPE 5. SESSION: UNDERSTANDING AND STRENGTHENING HOPE 6. SESSION: INTERNALIZING WHAT HAS BEEN LEARNED, MAINTAINING AND EVALUATING |
| routine nursing care | No intervention | –routine nursig care; n=25 No intervention was performed after the pre-test; routine nursing care was administered. The post-test was administered after 3 weeks. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- 18 years of age or older
- Diagnosis of hematologic malignancy
- Ability to read and write
- Volunteer to participate in the study
Key exclusion criteria (6 listed)
- Dementia and/or organic mental disorder
- Sensory loss related to vision and hearing
- Communication barrier
- Physical disability
- Respiratory distress
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Muscle RelaxationProgressive relaxation is a relaxation technique based on tensing and relaxing muscles in sequence. The goal is to achieve physical and mental relaxation by feeling the difference between tension and relaxation. It is frequently used for stress, anxiety, sleep problems, and psychosomatic disorders. When practiced regularly, it increases a person's ability to relax and contributes to their overall well-being. * Teaching progressive relaxation exercises to individuals diagnosed with cancer and supporting psychological well-being by reducing stress levels and increasing hope levels through these exercises (emotional gain) * Reducing muscle tension and providing physical relaxation (psychomotor gain) * To reduce stress and anxiety (emotional gain) * To increase body awareness (emotional gain) * To teach mental and physical relaxation (psychomotor gain) * To provide emotional relief (emotional gain) * To develop self-relaxation skills (psychomotor gain) | Behavioural | Progressive relaxation |
| psychoeducation or Atomoxetine or stimulants according to ADHD severityPsychoeducation is a structured educational process that provides individuals with information about mental illnesses, ways to cope with stress, and healthy living skills. The goal is to help the person understand their illness and symptoms, learn coping methods, and increase their compliance with treatment. It has both an informative and a supportive aspect. INTERVENTION B (PSYCHOEDUCATION) GROUP APPLICATION: * A total of 6 sessions will be held with patients in intervention group B, twice a week for 3 weeks. * Each session will last an average of 45 minutes. * The 'Perceived Stress Level' scale and the 'Herth Hope Index' scale will be administered after the first session. * The 'Perceived Stress Level' scale and the 'Herth Hope Index' scale will be administered after the final session. | Behavioural | psychoeducation |
Primary outcome
Herth hope index level scale
Time frame: 9 months
Herth Hope Index: Developed by Kaye Herth (1992), its validity and reliability in Turkish were studied by Aslan and colleagues (2007). The scale consists of a total of 12 items: "Future" (questions 1, 2, 6, 11), "Positive readiness and expectation" (questions 4, 7, 10, 12), and "Connections with oneself and others" (questions 3, 5, 8, 9).
perceived stress level scales
Time frame: 9 months
PERCEIVED STRESS SCALE: The adaptation of the perceived stress scale developed by Cohen, Kamarck, and Mermelsten (1983) into Turkish was carried out by Eskin et al. (2013). The perceived stress scale, consisting of a total of 14 items, aims to measure how stressful individuals perceive their life situations to be..
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Muscle Relaxation and psychoeducation or Atomoxetine or stimulants according to ADHD severity in people with Hematological Cancer, run by Necmettin Erbakan University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 15 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Herth hope index level scale (time frame: 9 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 May 2026.