StrokeREACT-AVCNCT07254195
Assessment of an Intensive Motor Telerehabilitation Program for Stroke Patients
A study testing Telerehabilitation program using the MindMotion GO device in people with Stroke, run by Hospices Civils de Lyon at 1 site in France.
Trial summary
Stroke is a major cause of motor disability, particularly hemiplegia, and its incidence is increasing as the population ages. Despite partial spontaneous recovery in the first three months, 80% of patients retain a motor deficit after six months, requiring intensive rehabilitation to maximize recovery. Read more about this study
- Who is it for?
- Ages 18 to 85 years
- Conditions the study is for
- Stroke
- What is being tested?
- Telerehabilitation program using the MindMotion GO device
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 51 participants
- Where
- 1 siteFrance
- Study dates
- 25 Feb 2026to 25 Jan 2028
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 85 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Hospitalized for a first ischemic or hemorrhagic stroke
- Stroke occurrence more than 30 days prior
- Presenting motor deficits affecting the upper limb, with or without involvement of the lower limb
- Able to follow the instructions of the home program using the MindMotion GO device
- Having at home an accessible email address, an Internet connection with password, a smartphone, a screen or TV with HDMI input (Full HD 1080p resolution), and a free space of approximately 1 m x 2.5 m in front of the screen
- Ability to sit without assistance
- Patient agreeing to participate in the study by signing an informed consent form
- Affiliated with, or entitled to, a social security scheme
Who cannot join
- History of stroke
- Neurological pathology other than stroke
- Patient with uncontrolled epilepsy or seizure disorder
- Cardiac disease limiting exercise
- Pain limiting rehabilitation dose
- Major comprehension problems or severe psychiatric and/or cognitive disorders that could compromise understanding of the protocol and the smooth running of the study.
Show all 16Show fewer
- Uncorrected hearing or visual deficits
- Severe apraxia
- Severe memory impairment
- Severe unilateral spatial neglect
- Total plegia of affected limb
- Pregnant, parturient or breast-feeding women
- Persons deprived of their liberty by judicial or administrative decision
- Persons admitted to a health or social institution for purposes other than research
- Adults under legal protection (guardianship, curatorship)
- Subjects participating in other intervention research.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
Hopital Henry Gabrielle
Saint-Genis-Laval, Lyon, 69230
Jacques LUAUTÉ, MD, PhD, 4 78 86 50 64 ext. +33, Jacques.luaute@chu-lyon.fr
About this study
Official title: Intensive Motor Rehabilitation of Stroke Patients: Evaluation of a Telerehabilitation Program
Stroke is a major cause of motor disability, particularly hemiplegia, and its incidence is increasing as the population ages. Despite partial spontaneous recovery in the first three months, 80% of patients retain a motor deficit after six months, requiring intensive rehabilitation to maximize recovery. However, after hospitalization, access to intensive rehabilitation is limited, due to geographical and mobility constraints, and the lack of reimbursement for private occupational therapy.
Telerehabilitation, using digital technologies, can overcome these difficulties by offering interactive, accessible rehabilitation at home. Studies show that its effectiveness is comparable to that of clinical rehabilitation.
Our study therefore proposes to evaluate the feasibility and effects of a home-based telerehabilitation program using the MindMotion GO device (MindMaze). This 12-week program aims to provide an additional intensive dose of rehabilitation to the standard of care, with 300 minutes of weekly active therapy, planned and monitored remotely by a therapist.
Read the detailed description
Stroke is a major cause of motor disability, particularly hemiplegia, and its incidence is increasing as the population ages. Despite partial spontaneous recovery in the first three months, 80% of patients retain a motor deficit after six months, requiring intensive rehabilitation to maximize recovery. However, after hospitalization, access to intensive rehabilitation is limited, due to geographical and mobility constraints, and the lack of reimbursement for private occupational therapy.
Telerehabilitation, using digital technologies, can overcome these difficulties by offering interactive, accessible rehabilitation at home. Studies show that its effectiveness is comparable to that of clinical rehabilitation.
Our study therefore proposes to evaluate the feasibility and effects of a home-based telerehabilitation program using the MindMotion GO device (MindMaze). This 12-week program aims to provide an additional intensive dose of rehabilitation to the standard of care, with 300 minutes of weekly active therapy, planned and monitored remotely by a therapist. It combines synchronous (1time a week with a therapist) and asynchronous (autonomous) sessions.
This program is integrated into the post-stroke care pathway by facilitating the transition from hospital to home, without prolonging hospitalization or increasing face-to-face sessions.
The study will be a single-center randomized controlled trial, targeting patients in the sub-acute and chronic stages of stroke.
- Conditions
- Stroke
- Being tested
- Telerehabilitation program using the MindMotion GO device
- Keywords
- Stroke, motor, telerehabilitation, intensive therapy
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Telerehabilitation program using the MindMotion GO deviceDevice
In parallel to the standard of care, patients will participate in a 12-weeks telerehabilitation program using the MindMotion GO device.
MindMotion GO is a digital therapy device that offers a catalog of interactive games designed specifically for patients with neurological injuries.
During the telerehabilitation program, patients will aim to achieve at least 300 minutes of active therapy per week. They will have 1 synchronous session per week in the clinic or remotely by videoconference with a therapist (PT or OT). Patients are expected to carry out the other planned sessions independently at home. The activity schedule will be drawn up by a remote therapist each week and will be personalized for each patient.
| Study group | Role | What they receive |
|---|---|---|
| TR1 | Other | Immediately following discharge from the rehabilitation unit, patients will participate in a 12-weeks telerehabilitation program using the MindMotion GO device, in parallel to the standard care.
During the 12-weeks program, patients will aim to achieve at least 300 minutes of active therapy time per week using the MindMotion GO device at their home. They will have 1 synchronous rehabilitation session per week in clinic or remotely via videoconference with a PT or an OT. The rest of the sessions will be done asynchronously and independently by the patient. The activity schedule will be drawn up by a therapist remotely and will be personalized for each patient.
After 12 weeks, the patients will be asked whether they wish to continue with the telerehabilitation program. Patients who agree to continue will pursue the program for another 12 weeks, in parallel to standard care.
Patients who do not want to continue the program will only receive standard care for the following 12 weeks. Receives: Device: Telerehabilitation program using the MindMotion GO device |
| TR2 | Other | Following discharge from the rehabilitation unit, patients will receive only standard care for 12 weeks.
Then, they will start the telerehabilitation program using the MindMotion GO device for 12 weeks, in parallel to the standard care. During the 12-weeks program, patients will aim to achieve at least 300 minutes of active therapy time per week using the MindMotion GO device at their home. They will have 1 synchronous rehabilitation session per week in clinic or remotely via videoconference with a PT or an OT. The rest of the sessions will be done asynchronously and independently by the patient. The activity schedule will be drawn up by a therapist remotely and will be personalized for each patient. Receives: Device: Telerehabilitation program using the MindMotion GO device |
What is being measured
The primary outcome is the main question the study is designed to answer.
Variation in the Goal Attainment Scale (GAS) score.
The GAS is used to measure achievement of individual goals. GAS goals will be set for each participant before the start of the intervention. Achievement of each objective will be rated on a 5-point scale: -2 (patient's initial, pre-intervention level), -1 (progress towards goal, without complete attainment), 0 (expected level), +1 (goal achieved better than expected), +2 (best hoped-for result).
Measured: Baseline, at 8, 20, 32 and 44 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Nov 2025
- Study start25 Feb 2026
- Primary completion25 Jan 2028 (estimated)
- Study completion25 Jan 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- More trials run by Hospices Civils de LyonThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 51 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Hospices Civils de Lyon
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07254195
- Sponsor's protocol ID
- 69HCL24_0504
- Other IDs
- 2025-A01054-45
- Acronym
- REACT-AVC
- Status last verified
- Mar 2026
- First submitted
- 19 Nov 2025
- Last updated
- 5 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 5 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Intensive Motor Rehabilitation of Stroke Patients: Evaluation of a Telerehabilitation Program
- ClinicalTrials.gov ID
- NCT07254195
- Acronym / sponsor ID
- REACT-AVC / 69HCL24_0504
- Conditions
- Stroke
- Keywords
- Stroke, motor, telerehabilitation, intensive therapy
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 51 participants (estimated)
- Lead sponsor
- Hospices Civils de LyonUniversity, hospital or other
- Study start
- 25 Feb 2026 (actual)
- Primary completion
- 25 Jan 2028 (estimated)
- Study completion
- 25 Jan 2028 (estimated)
- First posted
- 28 Nov 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Stroke is a major cause of motor disability, particularly hemiplegia, and its incidence is increasing as the population ages. Despite partial spontaneous recovery in the first three months, 80% of patients retain a motor deficit after six months, requiring intensive rehabilitation to maximize recovery. However, after hospitalization, access to intensive rehabilitation is limited, due to geographical and mobility constraints, and the lack of reimbursement for private occupational therapy.
Telerehabilitation, using digital technologies, can overcome these difficulties by offering interactive, accessible rehabilitation at home. Studies show that its effectiveness is comparable to that of clinical rehabilitation.
Our study therefore proposes to evaluate the feasibility and effects of a home-based telerehabilitation program using the MindMotion GO device (MindMaze). This 12-week program aims to provide an additional intensive dose of rehabilitation to the standard of care, with 300 minutes of weekly active therapy, planned and monitored remotely by a therapist.
Detailed description
Stroke is a major cause of motor disability, particularly hemiplegia, and its incidence is increasing as the population ages. Despite partial spontaneous recovery in the first three months, 80% of patients retain a motor deficit after six months, requiring intensive rehabilitation to maximize recovery. However, after hospitalization, access to intensive rehabilitation is limited, due to geographical and mobility constraints, and the lack of reimbursement for private occupational therapy.
Telerehabilitation, using digital technologies, can overcome these difficulties by offering interactive, accessible rehabilitation at home. Studies show that its effectiveness is comparable to that of clinical rehabilitation.
Our study therefore proposes to evaluate the feasibility and effects of a home-based telerehabilitation program using the MindMotion GO device (MindMaze). This 12-week program aims to provide an additional intensive dose of rehabilitation to the standard of care, with 300 minutes of weekly active therapy, planned and monitored remotely by a therapist. It combines synchronous (1time a week with a therapist) and asynchronous (autonomous) sessions.
This program is integrated into the post-stroke care pathway by facilitating the transition from hospital to home, without prolonging hospitalization or increasing face-to-face sessions.
The study will be a single-center randomized controlled trial, targeting patients in the sub-acute and chronic stages of stroke.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| TR1 | Other | Device: Telerehabilitation program using the MindMotion GO deviceImmediately following discharge from the rehabilitation unit, patients will participate in a 12-weeks telerehabilitation program using the MindMotion GO device, in parallel to the standard care. During the 12-weeks program, patients will aim to achieve at least 300 minutes of active therapy time per week using the MindMotion GO device at their home. They will have 1 synchronous rehabilitation session per week in clinic or remotely via videoconference with a PT or an OT. The rest of the sessions will be done asynchronously and independently by the patient. The activity schedule will be drawn up by a therapist remotely and will be personalized for each patient. After 12 weeks, the patients will be asked whether they wish to continue with the telerehabilitation program. Patients who agree to continue will pursue the program for another 12 weeks, in parallel to standard care. Patients who do not want to continue the program will only receive standard care for the following 12 weeks. |
| TR2 | Other | Device: Telerehabilitation program using the MindMotion GO deviceFollowing discharge from the rehabilitation unit, patients will receive only standard care for 12 weeks. Then, they will start the telerehabilitation program using the MindMotion GO device for 12 weeks, in parallel to the standard care. During the 12-weeks program, patients will aim to achieve at least 300 minutes of active therapy time per week using the MindMotion GO device at their home. They will have 1 synchronous rehabilitation session per week in clinic or remotely via videoconference with a PT or an OT. The rest of the sessions will be done asynchronously and independently by the patient. The activity schedule will be drawn up by a therapist remotely and will be personalized for each patient. |
Who may qualify
- Ages
- 18 to 85 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- Hospitalized for a first ischemic or hemorrhagic stroke
- Stroke occurrence more than 30 days prior
- Presenting motor deficits affecting the upper limb, with or without involvement of the lower limb
- Able to follow the instructions of the home program using the MindMotion GO device
- Having at home an accessible email address, an Internet connection with password, a smartphone, a screen or TV with HDMI input (Full HD 1080p resolution), and a free space of approximately 1 m x 2.5 m in front of the screen
Key exclusion criteria (16 listed)
- History of stroke
- Neurological pathology other than stroke
- Patient with uncontrolled epilepsy or seizure disorder
- Cardiac disease limiting exercise
- Pain limiting rehabilitation dose
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Telerehabilitation program using the MindMotion GO deviceIn parallel to the standard of care, patients will participate in a 12-weeks telerehabilitation program using the MindMotion GO device. MindMotion GO is a digital therapy device that offers a catalog of interactive games designed specifically for patients with neurological injuries. During the telerehabilitation program, patients will aim to achieve at least 300 minutes of active therapy per week. They will have 1 synchronous session per week in the clinic or remotely by videoconference with a therapist (PT or OT). Patients are expected to carry out the other planned sessions independently at home. The activity schedule will be drawn up by a remote therapist each week and will be personalized for each patient. | Device | TR1, TR2 |
Primary outcome
Variation in the Goal Attainment Scale (GAS) score.
Time frame: Baseline, at 8, 20, 32 and 44 weeks
The GAS is used to measure achievement of individual goals. GAS goals will be set for each participant before the start of the intervention. Achievement of each objective will be rated on a 5-point scale: -2 (patient's initial, pre-intervention level), -1 (progress towards goal, without complete attainment), 0 (expected level), +1 (goal achieved better than expected), +2 (best hoped-for result).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Mar 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Telerehabilitation program using the MindMotion GO device in people with Stroke, run by Hospices Civils de Lyon at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 16 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 5 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Jacques LUAUTÉ, MD (4 78 86 50 64 ext. +33, Jacques.luaute@chu-lyon.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Variation in the Goal Attainment Scale (GAS) score. (time frame: Baseline, at 8, 20, 32 and 44 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Mar 2026.