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Music TherapyNCT07255339

The Effect of Music Therapy on Pain and Anxiety in Patients After Coronary Artery Bypass Grafting

A study testing Music therapy group in people with Music Therapy and Pain, run by University of Gaziantep at 1 site in Turkey (Türkiye).

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

Coronary artery disease is a frequently occurring, life-threatening disease that has caused high morbidity and mortality, and has resulted in a high rate of death, both in our country and worldwide over the past five years. Read more about this study

Who is it for?
Ages 18 years and older
Conditions the study is for
Music Therapy, Pain, Anxiety
What is being tested?
Music therapy group
Could I receive a placebo?
No, everyone receives an active treatment
How many people
60 participants
Where
1 siteTurkey (Türkiye)
Study dates
29 Jul 2022to 16 Jun 2023
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Patients over 18 years of age with no hearing impairment
  • Planned for coronary artery bypass graft surgery
  • Not diagnosed with a psychiatric disorder and therefore not taking medication
  • Volunteer to participate in the study

Who cannot join

  • Patients who refuse to participate in the study
  • Patients who volunteer to participate and then withdraw from the study at any stage.

Trial locations and contacts

1 site in 1 country.

Turkey (Türkiye)1 site
  • SB.SBÜ. Van Eğitim ve Araştırma Hastanesi

    Van

Other trials in Turkey (Türkiye)

About this study

Coronary artery disease is a frequently occurring, life-threatening disease that has caused high morbidity and mortality, and has resulted in a high rate of death, both in our country and worldwide over the past five years. The most commonly used method for the treatment of coronary artery disease is coronary artery bypass grafting (CABG). This surgery aims to restore blood flow to the myocardium, which has become inadequate due to blockage or stenosis in the coronary arteries that feed the heart, by using an artery graft and to prolong life to a better standard. Surgical procedures such as coronary artery bypass grafting are psychologically, economically, socially, and physically detrimental to patients. Coronary artery bypass grafting, a major surgical procedure, can lead to serious postoperative complications. Some of these include postoperative pain and anxiety. Pain is one of the first complications observed, especially in the early postoperative period. The heart is one of the most important vital organs, and interventions in this regard trigger a fear of death in individuals and, consequently, cause them to experience significant anxiety after the operation. In addition to pharmacological methods, non-pharmacological methods are also used in pain and anxiety management. Music therapy is one of these methods used in the treatment of pain and anxiety. Music has always been a cultural and universal heritage of societies, present from past to present. Music therapy is a specialized field that incorporates the patient's body, mind, and spirit integrity, facilitates treatment using evidence-based practices, and utilizes all aspects of music within a therapeutic relationship to alleviate patient distress. Music therapy has consistently been a part of treatment methods from past to present and has been shown to have positive effects. Depression can affect stress hormones, leading to an increase in heart rate and an imbalance in oxygen demand. Disruption of sleep patterns before surgery can lead to anxiety and pain. Previous studies have shown that music therapy balances the body, mind, and spirit integrity of individuals within the endocrine and nervous systems.

Read the detailed description

Coronary artery disease (CAD) has remained one of the leading causes of high morbidity and mortality both in our country and worldwide over the past five years. According to global epidemiological data, cardiovascular diseases account for nearly one-third of all deaths, making them a major public health concern. CAD is characterized by atherosclerotic plaque formation and the narrowing of coronary vessels, which results in reduced myocardial oxygenation. As the disease progresses, coronary artery bypass grafting (CABG) becomes one of the most commonly used and effective treatment methods. The primary goal of CABG is to restore myocardial blood flow distal to the stenotic or occluded coronary artery by using arterial or venous grafts, thereby improving cardiac perfusion and enhancing both quality of life and overall survival.

CABG is a major surgical intervention that imposes significant psychological, physiological, social, and economic burdens on patients. In the postoperative period, patients frequently experience severe pain, anxiety, sleep disturbances, stress, depressive symptoms, hemodynamic instability, and reduced quality of life. The intensity of postoperative pain is affected by the invasiveness of the procedure, such as sternotomy, placement of chest tubes, surgical drains, and limited mobility. Moreover, undergoing a surgical procedure involving the heart-a vital organ-often triggers fear of death, a sense of loss of control, uncertainty about recovery, and concerns about postoperative complications, all of which contribute to heightened anxiety levels.

While pharmacological treatments are essential in managing postoperative pain and anxiety, they are often insufficient on their own. For this reason, non-pharmacological interventions are increasingly recommended as complementary approaches during the recovery process. Among these interventions-such as breathing exercises, relaxation techniques, massage therapy, and aromatherapy-music therapy has gained particular attention due to its demonstrated benefits.

Music therapy is a specialized, evidence-based discipline that utilizes the therapeutic elements of music within a structured patient-therapist relationship to support the individual's physical, psychological, and spiritual well-being. By employing components such as rhythm, melody, and harmony, music therapy aims to regulate emotional responses and promote healing. Studies have shown that music has significant effects on the autonomic nervous system; it activates the parasympathetic system, helping to stabilize heart rate, reduce blood pressure, regulate breathing, and decrease levels of stress-related hormones, including cortisol. Consequently, music therapy alleviates both the perception of pain and anxiety.

Furthermore, disruptions in sleep patterns prior to surgery can exacerbate anxiety and pain, while chronic stress and elevated stress hormones may negatively affect heart rate, oxygen demand, and overall cardiopulmonary stability. Previous research has demonstrated that music therapy can help regulate the mind-body-spirit connection within the endocrine and nervous systems, thereby promoting physiological balance and emotional comfort in individuals undergoing major surgical procedures such as CABG.

Being tested
Music therapy group
Keywords
Coronary artery bypass grafting, Music therapy, Pain, Anxiety, Randomized controlled trial
Medical subject headings
Pain, Anxiety Disorders

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Music therapy groupOther

    In the study, patients undergoing coronary artery bypass graft surgery will be exposed to music before and during surgery. The Beck Anxiety Inventory and Visual Analog Scale will be administered postoperatively.

Study groups in NCT07255339
Study groupRoleWhat they receive
Music therapy groupActive comparatorMusic therapy group
Receives: Other: Music therapy group
Control groupNo interventionControl group

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. The effect of music played on anxiety in patients undergoing coronary artery bypass graft surgery

    "Not at all" indicates no anxiety at all, while "I had a very hard time tolerating it at a serious level" indicates the highest possible anxiety.

    Measured: From enrollment to the end of treatment at one years

  2. The effect of music played on pain in patients undergoing coronary artery bypass graft surgery

    Zero is equivalent to no pain, and 10 indicates the worst possible pain

    Measured: From enrollment to the end of treatment at one years

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted1 Dec 2025
  2. Study start29 Jul 2022
  3. Primary completion8 Nov 2022
  4. Study completion16 Jun 2023

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Other
Allocation
Randomised
Intervention model
Single group
Masking
None (open label)
Enrolment
60 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07255339
Sponsor's protocol ID
2022/17-03
Status last verified
Nov 2025
First submitted
15 Nov 2025
Last updated
5 Dec 2025
Results posted
No
Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No: I do not plan to share your IPD with other researchers.

Questions about this trial

What is this clinical trial studying?

A study testing Music therapy group in people with Music Therapy and Pain, run by University of Gaziantep at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 4 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 5 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

The effect of music played on anxiety in patients undergoing coronary artery bypass graft surgery (time frame: From enrollment to the end of treatment at one years). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Dec 2025.

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