Nasolacrimal Duct ObstructionNCT07289854
Portable Endoscopic Camera System Using Modified Action Camera for Endoscopic Sinunasal Examination
An observational study of Nasolacrimal Duct Obstruction and Nasolacrimal Tract Obstruction, run by University of Arkansas at 1 site in United States.
Trial summary
This study is designed to compare two methods for performing a nasal endoscopic examination used in the evaluation of excessive watering or tearing of the eyes. The purpose of the study is to determine whether a new, smaller, modified camera system can produce images of the inside of the nose that are as clear and… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Nasolacrimal Duct Obstruction, Nasolacrimal Tract Obstruction
- What is being tested?
- Modified Portable Endoscopic Camera
- Type of treatment
- Medical device
- How many people
- 22 participants
- Where
- 1 siteUnited States
- Study dates
- 16 Dec 2025to 23 Jul 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Adults receiving care in the ophthalmology or otolaryngology outpatient clinics at the University of Arkansas for Medical Sciences (UAMS) who present with sinonasal or lacrimal tearing symptoms and require nasal endoscopic evaluation as part of routine clinical care. Potential participants will be identified only during their scheduled clinic visits, and no individuals will be contacted in advance. Eligibility confirmation will be based solely on information already available in the medical record during standard outpatient workflow. Individuals who meet eligibility will be approached in person during the clinic visit and invited to participate.
Who may be able to join
- Adult patients (≥ 18 years old) undergoing a clinically indicated nasal endoscopic examination
- Patients may include, but are not limited to, those presenting with tearing suggestive of nasolacrimal drainage obstruction or sinonasal disease
Who cannot join
- Children (Under the age of 18)
- Patients with over secretory tearing without clinical indication for nasal endoscopy
Trial locations and contacts
1 site in 1 country.
United States1 site
University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205
About this study
This study is designed to compare two methods for performing a nasal endoscopic examination used in the evaluation of excessive watering or tearing of the eyes. The purpose of the study is to determine whether a new, smaller, modified camera system can produce images of the inside of the nose that are as clear and useful as those produced by the standard endoscopic camera system currently used in clinics.
The study seeks to answer the question of whether a compact, easy-to-store camera system can provide similar diagnostic image quality to the traditional, larger tower-based system. The clinical steps of the nasal examination remain the same; the only difference is the type of camera system used to capture the images.
Read the detailed description
This study evaluates two imaging systems used during routine nasal endoscopy performed for assessment of epiphora and related nasolacrimal or sinonasal concerns. The protocol involves conducting a standard nasal endoscopic examination with the conventional full-size tower-mounted camera system typically utilized in ophthalmology and otolaryngology outpatient settings, followed by a second examination using a modified compact camera system. Both examinations use the same endoscope and follow identical clinical steps.
The modified camera system attaches at the usual hand-position point on the endoscope and is designed to reduce equipment footprint, increase portability, and simplify storage. The second examination adds an estimated 3-5 minutes to the clinical encounter and does not introduce additional maneuvers or diagnostic procedures.
The primary objective is to compare image quality between the standard system and the compact system. Secondary objectives include assessments of device usability, handling characteristics, and overall feasibility of integrating the compact system into routine clinical workflow.
This evaluation aims to determine whether the compact camera system can provide imaging performance comparable to the traditional tower-based system while offering potential operational benefits. These benefits may include improved flexibility in space-constrained environments, reduced dependence on fixed equipment, and expanded opportunities for nasal endoscopy in clinics with limited infrastructure. Findings may inform future decisions regarding endoscopic equipment selection across various clinical settings.
- Being tested
- Modified Portable Endoscopic Camera
- Medical subject headings
- Lacrimal Duct Obstruction
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Modified Portable Endoscopic CameraDevice
The Sony Action Camera was modified to allow direct coupling with a standard rigid nasal endoscope:
- The native 180° wide-angle lens was replaced with a narrow-field 31° lens, enabling full-frame capture of the endoscopic image without peripheral distortion.
- The camera housing was adapted by attaching a ¾-inch water pipe end connector, serving as a secure and stable mount for the endoscope eyepiece.
The modified system captures both video and still images.
| Study group | Role | What they receive |
|---|---|---|
| Modified Portable Endoscopic Camera | Not described Receives: Device: Modified Portable Endoscopic Camera |
What is being measured
The primary outcome is the main question the study is designed to answer.
Image Quality Score of Modified Portable Endoscopic Camera System
Image quality of the modified portable endoscopic camera system will be evaluated using a 5-point Likert scale assessing resolution, clarity of anatomical structures, and overall clinical utility. Three attending physicians will independently grade anonymized images from each nasal anatomical site. Scores will be compared with those obtained from the standard endoscopic tower.
Measured: Grading completed within 3 months of enrollment completion.
Secondary outcomes (1)
Image Quality Score of Standard Endoscopic Tower System
Image quality of the standard endoscopic tower will be evaluated using the same 5-point Likert grading scale and process applied to the modified system. These scores will serve as the comparator for paired analysis.
Measured: Grading completed within 3 months of enrollment completion.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted17 Dec 2025
- Study start16 Dec 2025
- Primary completion23 Jul 2026
- Study completion23 Jul 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Nasolacrimal Duct ObstructionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 22 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Arkansas
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Omar Solyman, MD, Principal investigator, University Of Arkansas For Medical Sciences, Jones Eye Institute
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07289854
- Sponsor's protocol ID
- 299385
- Status last verified
- Aug 2026
- First submitted
- 4 Dec 2025
- Last updated
- 11 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 11 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Portable Endoscopic Camera System Using Modified Action Camera for Endoscopic Sinunasal Examination
- ClinicalTrials.gov ID
- NCT07289854
- Acronym / sponsor ID
- 299385
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 22 participants (actual)
- Lead sponsor
- University of ArkansasUniversity, hospital or other
- Study start
- 16 Dec 2025 (actual)
- Primary completion
- 23 Jul 2026 (actual)
- Study completion
- 23 Jul 2026 (actual)
- First posted
- 17 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is designed to compare two methods for performing a nasal endoscopic examination used in the evaluation of excessive watering or tearing of the eyes. The purpose of the study is to determine whether a new, smaller, modified camera system can produce images of the inside of the nose that are as clear and useful as those produced by the standard endoscopic camera system currently used in clinics.
The study seeks to answer the question of whether a compact, easy-to-store camera system can provide similar diagnostic image quality to the traditional, larger tower-based system. The clinical steps of the nasal examination remain the same; the only difference is the type of camera system used to capture the images.
Detailed description
This study evaluates two imaging systems used during routine nasal endoscopy performed for assessment of epiphora and related nasolacrimal or sinonasal concerns. The protocol involves conducting a standard nasal endoscopic examination with the conventional full-size tower-mounted camera system typically utilized in ophthalmology and otolaryngology outpatient settings, followed by a second examination using a modified compact camera system. Both examinations use the same endoscope and follow identical clinical steps.
The modified camera system attaches at the usual hand-position point on the endoscope and is designed to reduce equipment footprint, increase portability, and simplify storage. The second examination adds an estimated 3-5 minutes to the clinical encounter and does not introduce additional maneuvers or diagnostic procedures.
The primary objective is to compare image quality between the standard system and the compact system. Secondary objectives include assessments of device usability, handling characteristics, and overall feasibility of integrating the compact system into routine clinical workflow.
This evaluation aims to determine whether the compact camera system can provide imaging performance comparable to the traditional tower-based system while offering potential operational benefits. These benefits may include improved flexibility in space-constrained environments, reduced dependence on fixed equipment, and expanded opportunities for nasal endoscopy in clinics with limited infrastructure. Findings may inform future decisions regarding endoscopic equipment selection across various clinical settings.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Modified Portable Endoscopic Camera | – | Device: Modified Portable Endoscopic Camera |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Adults receiving care in the ophthalmology or otolaryngology outpatient clinics at the University of Arkansas for Medical Sciences (UAMS) who present with sinonasal or lacrimal tearing symptoms and require nasal endoscopic evaluation as part of routine clinical care. Potential participants will be identified only during their scheduled clinic visits, and no individuals will be contacted in advance. Eligibility confirmation will be based solely on information already available in the medical record during standard outpatient workflow. Individuals who meet eligibility will be approached in person during the clinic visit and invited to participate.
Key inclusion criteria (2 listed)
- Adult patients (≥ 18 years old) undergoing a clinically indicated nasal endoscopic examination
- Patients may include, but are not limited to, those presenting with tearing suggestive of nasolacrimal drainage obstruction or sinonasal disease
Key exclusion criteria (2 listed)
- Children (Under the age of 18)
- Patients with over secretory tearing without clinical indication for nasal endoscopy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Modified Portable Endoscopic CameraThe Sony Action Camera was modified to allow direct coupling with a standard rigid nasal endoscope: 1. The native 180° wide-angle lens was replaced with a narrow-field 31° lens, enabling full-frame capture of the endoscopic image without peripheral distortion. 2. The camera housing was adapted by attaching a ¾-inch water pipe end connector, serving as a secure and stable mount for the endoscope eyepiece. The modified system captures both video and still images. | Device | Modified Portable Endoscopic Camera |
Primary outcome
Image Quality Score of Modified Portable Endoscopic Camera System
Time frame: Grading completed within 3 months of enrollment completion.
Image quality of the modified portable endoscopic camera system will be evaluated using a 5-point Likert scale assessing resolution, clarity of anatomical structures, and overall clinical utility. Three attending physicians will independently grade anonymized images from each nasal anatomical site. Scores will be compared with those obtained from the standard endoscopic tower.
1 secondary outcome
Image Quality Score of Standard Endoscopic Tower System
Time frame: Grading completed within 3 months of enrollment completion.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Aug 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Omar Solyman, MD principal investigator
University Of Arkansas For Medical Sciences, Jones Eye Institute
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Nasolacrimal Duct Obstruction and Nasolacrimal Tract Obstruction, run by University of Arkansas at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 11 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Image Quality Score of Modified Portable Endoscopic Camera System (time frame: Grading completed within 3 months of enrollment completion.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Aug 2026.