Aesthetic ProceduresNCT07296601
Expert Consensus on the Clinical Use of Skin Boosters: A Delphi-Based Recommendation Framework
An observational study of Aesthetic Procedures and Cosmetic Techniques, run by Venus Research Center at 1 site in Egypt.
Trial summary
This consensus research project aims to develop standardized, evidence-based recommendations for the clinical use of skin boosters in aesthetic dermatology. Despite their widespread adoption for improving skin hydration, texture, and dermal quality, current practice patterns vary significantly across clinicians and… Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Aesthetic Procedures, Cosmetic Techniques, Skin Ageing
- How many people
- 15 participants
- Where
- 1 siteEgypt
- Study dates
- 25 Dec 2025to 1 Jan 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: The study population will consist of a purposively selected panel of experts in aesthetic dermatology and skin booster therapy. Participants will include board-certified dermatologists, aesthetic physicians, and plastic surgeons with substantial clinical experience in administering injectable skin quality treatments. The expert panel will represent a diverse range of clinical backgrounds, geographical regions, and practice settings to ensure comprehensive and balanced perspectives.
Who may be able to join
- Experts will be eligible to participate if they meet all of the following:
- Board-certified dermatologist or aesthetic physician
- With recognized qualification in dermatology, aesthetic medicine, plastic surgery, or related fields.
- Minimum clinical experience
- At least 5 years of experience performing aesthetic injectable procedures.
- OR at least 3 years of consistent use of skin boosters in clinical practice.
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- Demonstrated expertise in skin booster therapy
- Must have performed ≥100 skin booster procedures overall,
- OR ≥20 sessions per year over the past 2 years.
- Active clinical practice
- Currently practicing in an aesthetic or dermatology clinic, medical center, or hospital.
- Authorship or contribution to aesthetic/dermatology education (desirable but not mandatory)
- Publications, lectures, workshop instruction, or conference involvement in aesthetics.
- Ability to participate in Delphi rounds
- Must agree to complete all survey rounds within the specified timeframe.
- Must be fluent in the language used for the study (e.g., English or Arabic).
- Willingness to provide informed consent
- Voluntary participation with confidentiality maintained.
Who cannot join
- Less than the required experience
- <5 years of aesthetic practice
- OR insufficient hands-on experience with skin booster injections.
- Limited familiarity with skin booster products or techniques
- No regular use in the last 2 years.
- Has not performed the minimum number of required procedures.
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- Industry conflict of interest
- Direct employment by a company manufacturing skin booster products.
- Significant financial relationship with a single product manufacturer that may bias responses.
- Inability to commit to multiple Delphi rounds
- Anticipated non-compliance or non-response in iterative rounds.
- Non-clinical or administrative professionals
- Those not actively practicing (e.g., retired, research-only positions, students, trainees).
- Participation in a competing guideline project
- Experts currently serving on another skin booster consensus panel to avoid duplication or bias.
- Failure to provide informed consent
- Declines participation or withdraws consent at any time.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
This consensus research project aims to develop standardized, evidence-based recommendations for the clinical use of skin boosters in aesthetic dermatology. Despite their widespread adoption for improving skin hydration, texture, and dermal quality, current practice patterns vary significantly across clinicians and regions, with limited unified guidelines. Using a structured Delphi methodology, the study will gather expert opinions from dermatologists and aesthetic medicine specialists to achieve agreement on key aspects of skin booster therapy, including indications, patient selection, injection techniques, dosing protocols, product selection, treatment intervals, expected outcomes, and safety considerations.
The project seeks to establish practical, consensus-driven guidelines that can harmonize clinical practice, enhance treatment outcomes, and ensure patient safety. The final recommendations will serve as a reference framework for practitioners and contribute to the standardization of skin quality enhancement treatments.
Read the detailed description
Skin boosters have become an increasingly popular modality in aesthetic dermatology due to their ability to enhance skin hydration, elasticity, texture, and overall dermal quality through minimally invasive intradermal injections. Despite their rapid integration into clinical practice, current approaches to skin booster therapy remain highly variable. Differences exist in product selection, injection depth, dosing regimens, treatment intervals, technique, indications, and safety monitoring. Moreover, the evidence base is still evolving, and most available data come from fragmented clinical studies or manufacturer-driven guidelines. As a result, there is a significant need for unified, expert-driven recommendations that can standardize practice, optimize patient outcomes, and minimize complications.
This research project aims to develop comprehensive, evidence-informed consensus guidelines for the use of skin boosters in aesthetic practice. The study will use a structured Delphi methodology to gather and synthesize the perspectives of leading dermatologists and aesthetic medicine specialists. Through multiple iterative rounds, experts will evaluate and rate a series of statements addressing key clinical domains including: appropriate indications; patient selection criteria; anatomical considerations; recommended injection depths and techniques; dosing strategies; frequency and number of treatment sessions; choice of products (e.g., HA-based, polynucleotides, bio-remodeling agents); combination therapies; expected outcomes; management of adverse events; and contraindications.
The consensus-building process ensures anonymity, reduces bias, and encourages equal participation among experts. Quantitative analyses (e.g., percentage agreement thresholds, median and interquartile range scoring) will be used to determine which statements achieve consensus. Statements not reaching agreement will be revised and re-evaluated in subsequent rounds until final consensus is achieved.
By the end of the project, the expert panel will produce clear, standardized, and clinically actionable recommendations that can be used globally or regionally to harmonize the use of skin boosters. These guidelines will support clinicians by improving the consistency and quality of care, informing training programs, guiding patient counseling, and reducing complication rates. Ultimately, the project aims to fill a critical gap in aesthetic dermatology literature by establishing a scientifically grounded, consensus-driven framework for safe and effective skin booster therapy
- Conditions
- Aesthetic Procedures, Cosmetic Techniques, Skin Ageing
- Keywords
- Skin booster, rejuvenation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Expert Panel | A cohort of dermatology and aesthetic medicine experts participating in a Modified Delphi process to develop consensus recommendations on skin booster use. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Degree of Consensus on Clinical Recommendations
- Degree of Consensus on Clinical Recommendations Definition: The level of expert agreement on each statement related to skin booster therapy. Measurement Method: Likert scale ratings (e.g., 1-9). Consensus threshold often defined as: ≥75% agreement within the 7-9 range (agreement) ≤15% ratings in the 1-3 range (disagreement) Outcome: Identification of statements that meet consensus criteria for inclusion in the final guideline.
- Development of Final Consensus Guidelines
Definition: The creation of a unified, evidence-informed set of recommendations on skin booster use.
Measurement Method:
Number of statements that reach consensus across all Delphi rounds.
Completeness of guideline domains (indications, technique, dosing, safety, etc.).
Outcome: A finalized recommendations document for clinicians.
Measured: 6-12 weeks
Secondary outcomes (1)
Implementation Readiness of Final Recommendations
Definition: Practicality and ease of applying the guidelines in real-world clinical settings.
Measurement Method:
Expert evaluation of feasibility (Likert scale).
Assessment of clarity and actionability of statements.
Outcome: Determines how applicable the recommendations are in routine practice.
Measured: 6-12 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Dec 2025
- Study start25 Dec 2025 (estimated)
- Primary completion1 Dec 2026 (estimated)
- Study completion1 Jan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Aesthetic ProceduresStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 15 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Venus Research Center
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07296601
- Sponsor's protocol ID
- Skin Booster-VenusRC
- Status last verified
- Dec 2025
- First submitted
- 8 Dec 2025
- Last updated
- 22 Dec 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Delphi studies do not collect patient data, medical records, biological samples, or identifiable clinical information. Experts only give opinions, not "IPD." Their responses are anonymized, and sharing identifiable expert-level responses is not required and often discouraged
Study at a glance
From the registry record, last updated by the sponsor on 22 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Expert Consensus on the Clinical Use of Skin Boosters: A Delphi-Based Recommendation Framework
- ClinicalTrials.gov ID
- NCT07296601
- Acronym / sponsor ID
- Skin Booster-VenusRC
- Conditions
- Aesthetic Procedures, Cosmetic Techniques, Skin Ageing
- Keywords
- Skin booster, rejuvenation
- Study type
- Observational
- Recruitment status
- Enrolling by invitation
- Enrolment
- 15 participants (estimated)
- Lead sponsor
- Venus Research CenterUniversity, hospital or other
- Study start
- 25 Dec 2025 (estimated)
- Primary completion
- 1 Dec 2026 (estimated)
- Study completion
- 1 Jan 2027 (estimated)
- First posted
- 22 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This consensus research project aims to develop standardized, evidence-based recommendations for the clinical use of skin boosters in aesthetic dermatology. Despite their widespread adoption for improving skin hydration, texture, and dermal quality, current practice patterns vary significantly across clinicians and regions, with limited unified guidelines. Using a structured Delphi methodology, the study will gather expert opinions from dermatologists and aesthetic medicine specialists to achieve agreement on key aspects of skin booster therapy, including indications, patient selection, injection techniques, dosing protocols, product selection, treatment intervals, expected outcomes, and safety considerations.
The project seeks to establish practical, consensus-driven guidelines that can harmonize clinical practice, enhance treatment outcomes, and ensure patient safety. The final recommendations will serve as a reference framework for practitioners and contribute to the standardization of skin quality enhancement treatments.
Detailed description
Skin boosters have become an increasingly popular modality in aesthetic dermatology due to their ability to enhance skin hydration, elasticity, texture, and overall dermal quality through minimally invasive intradermal injections. Despite their rapid integration into clinical practice, current approaches to skin booster therapy remain highly variable. Differences exist in product selection, injection depth, dosing regimens, treatment intervals, technique, indications, and safety monitoring. Moreover, the evidence base is still evolving, and most available data come from fragmented clinical studies or manufacturer-driven guidelines. As a result, there is a significant need for unified, expert-driven recommendations that can standardize practice, optimize patient outcomes, and minimize complications.
This research project aims to develop comprehensive, evidence-informed consensus guidelines for the use of skin boosters in aesthetic practice. The study will use a structured Delphi methodology to gather and synthesize the perspectives of leading dermatologists and aesthetic medicine specialists. Through multiple iterative rounds, experts will evaluate and rate a series of statements addressing key clinical domains including: appropriate indications; patient selection criteria; anatomical considerations; recommended injection depths and techniques; dosing strategies; frequency and number of treatment sessions; choice of products (e.g., HA-based, polynucleotides, bio-remodeling agents); combination therapies; expected outcomes; management of adverse events; and contraindications.
The consensus-building process ensures anonymity, reduces bias, and encourages equal participation among experts. Quantitative analyses (e.g., percentage agreement thresholds, median and interquartile range scoring) will be used to determine which statements achieve consensus. Statements not reaching agreement will be revised and re-evaluated in subsequent rounds until final consensus is achieved.
By the end of the project, the expert panel will produce clear, standardized, and clinically actionable recommendations that can be used globally or regionally to harmonize the use of skin boosters. These guidelines will support clinicians by improving the consistency and quality of care, informing training programs, guiding patient counseling, and reducing complication rates. Ultimately, the project aims to fill a critical gap in aesthetic dermatology literature by establishing a scientifically grounded, consensus-driven framework for safe and effective skin booster therapy
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Expert Panel | – | –A cohort of dermatology and aesthetic medicine experts participating in a Modified Delphi process to develop consensus recommendations on skin booster use. |
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- The study population will consist of a purposively selected panel of experts in aesthetic dermatology and skin booster therapy. Participants will include board-certified dermatologists, aesthetic physicians, and plastic surgeons with substantial clinical experience in administering injectable skin quality treatments. The expert panel will represent a diverse range of clinical backgrounds, geographical regions, and practice settings to ensure comprehensive and balanced perspectives.
Key inclusion criteria (18 listed)
- Board-certified dermatologist or aesthetic physician
- With recognized qualification in dermatology, aesthetic medicine, plastic surgery, or related fields.
- Minimum clinical experience
- At least 5 years of experience performing aesthetic injectable procedures.
- OR at least 3 years of consistent use of skin boosters in clinical practice.
Key exclusion criteria (17 listed)
- Less than the required experience
- <5 years of aesthetic practice
- OR insufficient hands-on experience with skin booster injections.
- Limited familiarity with skin booster products or techniques
- No regular use in the last 2 years.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Degree of Consensus on Clinical Recommendations
Time frame: 6-12 weeks
1. Degree of Consensus on Clinical Recommendations Definition: The level of expert agreement on each statement related to skin booster therapy. Measurement Method: Likert scale ratings (e.g., 1-9). Consensus threshold often defined as: ≥75% agreement within the 7-9 range (agreement) ≤15% ratings in the 1-3 range (disagreement) Outcome: Identification of statements that meet consensus criteria for inclusion in the final guideline. 2. Development of Final Consensus Guidelines Definition: The creation of a unified, evidence-informed set of recommendations on skin booster use. Measurement Method: Number of statements that reach consensus across all Delphi rounds. Completeness of guideline domains (indications, technique, dosing, safety, etc.). Outcome: A finalized recommendations document for clinicians.
1 secondary outcome
Implementation Readiness of Final Recommendations
Time frame: 6-12 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Dec 2025.
- Individual participant dataSharing planned: No. Delphi studies do not collect patient data, medical records, biological samples, or identifiable clinical information. Experts only give opinions, not "IPD." Their responses are anonymized, and sharing identifiable expert-level responses is not required and often discouraged
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Aesthetic Procedures and Cosmetic Techniques, run by Venus Research Center at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 18 inclusion and 17 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 22 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Degree of Consensus on Clinical Recommendations (time frame: 6-12 weeks). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Dec 2025.