Clinical trials: Skin Ageing
Facial Aging
Facial Muscle Exercises vs Fractional Microneedling Radiofrequency for Facial Rejuvenation
This randomized controlled trial compared the effectiveness and safety of fractional microneedling radiofrequency (FMR) and facial muscle exercises (FME) for facial rejuvenation in females with mild to moderate facial aging.
- Trial name
- NCT07285577
- Testing
- Facial Muscle Exercise Program, Vivace® Fractional Microneedling Radiofrequency
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kasr El Aini Hospital
Skin Aging
A Comparative Split-Face Study of the Effects of a Retinol Alternative Cream on Improving Facial Skin Aging
This study will evaluate the efficacy of the DIME TBT Cream in improving the appearance and hydration of aged skin in comparison to a retinol cream. This study will last for 60 days.
- Trial name
- NCT06125912
- Testing
- Dime Beauty TBT Cream, Positive Control
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Dime Beauty Co.
Lipoatrophy, Aging
Safety Study of Antria Cell Preparation Process to Enhance Facial Fat Grafting With Adipose Derived Stem Cells
The primary purpose of this study is to demonstrate the safety of injecting the Stromal Vascular Fraction (SVF) [containing Adipose Derived Stem Cells (ADSCs)] enriched fat grafts into regions of the face that require…
- Conditions
- Lipoatrophy, Aging, Wrinkles
- Trial name
- NCT01828723
- Testing
- SVF
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Antria
Skin Aging
A Clinical Study to Evaluate the Efficacy and Safety of Monopolar Radiofrequency Combined With SkinCeuticals A.G.E and Skinceuticals CE FERULIC for Improving Facial Skin Elasticity, Tightening and Fading Fine Lines
A Prospective, Single-center, Single-blind, Randomized split-face, controlled trial will be conducted. The goal of this clinical trial is to evaluate the efficacy and safety of monopolar radiofrequency combined with SkinCeuticals…
- Trial name
- NCT06228833
- Testing
- monopolar radiofrequency, SkinCeuticals A.G.E and Skinceuticals CE FERULIC, Standard Cream
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Yes Skin Medical Group
Aging, Skin Wrinkling
Safety and Effectiveness of STYLAGE® L for Correction of Moderate and Severe Nasolabial Folds in Chinese Adults
This is a safety and efficacy study of STYLAGE® Lin Chinese adults with Nasolabial Folds.
- Trial name
- NCT04861766
- Testing
- STYLAGE® L, Active Comparator
- Where
- 8 sites in China
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- Laboratoires Vivacy
Skin Aging, Skin Hydration
Skin Hydration and Facial Aging in Women Aged 30-60: An Observational Correlational Study Using Bioimpedance Analysis
This study investigates whether skin hydration levels are related to how old the skin looks. Thirty women aged 30 to 60 years will attend a single visit at a licensed esthetic practice in Florida.
- Conditions
- Skin Aging, Skin Hydration, Facial Aging, Transepidermal Water Loss
- Trial name
- SHFA-30-60 (NCT07564869)
- Testing
- BT-Analyze Bioimpedance Measurement
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IAS Skin Care
Skin Aging, Fine Lines of the Face and Neck
TEOSYAL RHA® 1 for Neck Lines, Perioral Lines and Smiling Lines
Prospective, low-interventional, multicentric, open-labelled study to assess the performance and safety of skin beautification treatment by TEOSYAL RHA® 1 for fine lines in the neck, perioral region, and smiling lines including…
- Trial name
- NCT05349799
- Testing
- TEOSYAL RHA® 1, TEOSYAL RHA® 1 and TEOSYAL® PureSense Redensity 1 (needle), TEOSYAL RHA® 1 and TEOSYAL® PureSense Redensity 1 (cannula)
- Where
- 4 sites in Spain
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Teoxane SA
Breast Cancer
Impact of Home-based Aerobic and Strength Exercises During Chemotherapy for Early Breast Cancer on Biomarkers of Aging
Purpose: To determine if engagement in physical activity during chemotherapy will have a moderating effect on increases in p16 levels during chemotherapy.
- Trial name
- NCT03761706
- Testing
- Engagement in Physical Activity, Questionnaires
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Skin Ageing
Effect of Pomanox® on Skin Ageing (POMASKIN)
The state of skin health impacts not only on the general health of individuals, but also on mental health. Ultraviolet radiation (UV) is one of the main external factors that causes skin ageing, producing photo-aging…
- Trial name
- POMASKIN (NCT05842447)
- Testing
- 367 mg Pomanox group, 700 mg Pomanox group, Control group
- Where
- 2 sites in Spain
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fundació Eurecat
Healthy Volunteers
Evaluation of the Anti-aging Efficacy of Two Dietary Supplements
The study is aimed to assess the efficacy of two dietary supplements composed of berry extracts in reducing skin aging signs and improving skin complexion.
- Trial name
- NCT06032598
- Testing
- Berry extract 1, Berry extract 2
- Where
- Italy
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Seppic
Skin Aging, Facial Rhytides
AnteAGE Biosomes With Radiofrequency Microneedling for Facial Skin Rejuvenation
This prospective, randomized controlled study evaluated the efficacy and tolerability of AnteAGE Biosome Solution used in conjunction with facial radiofrequency microneedling.
- Conditions
- Skin Aging, Facial Rhytides, Skin Tone
- Trial name
- NCT07849556
- Testing
- AnteAGE Biosome Treatment Solution, Radiofrequency Microneedling, AnteAGE Homecare Regimen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cellese Inc.
Rheumatoid Arthritis
STudying Ageing in Rheumatic Diseases (STAR)
The primary objective of the STAR study is to investigate how measures of disease activity and measures for cognition, physical activity and performance behave in ageing population controls and patients with rheumatoid arthritis…
- Trial name
- NCT05463666
- Testing
- Rheumatoid arthritis
- Where
- Netherlands
- Volunteers
- 840 people
- Sponsor
- Maastricht University Medical Center
Skin Aging of Dorsal Hands
Comparing Pain, Safety and Effectiveness of Restylane Skinboosters Vital Lido and Vital Without Lido in Dorsal Hand
This is a randomized, multi-center, split-hand, subject-blinded study comparing pain, safety and effectiveness of Restylane Skinboosters Vital Lidocaine and Restylane Vital without lidocaine for improving appearance of the dorsal…
- Trial name
- NCT06372782
- Testing
- Restylane Skinboosters Vital Lidocaine, Restylane Vital
- Where
- 3 sites in China
- Volunteers
- 90 people
- Sponsor
- Galderma R&D
Aging, Premature
Safety and Performance of DKL Crosslinked Sodium Hyaluronate 23 Dermal Filler for Improvement of NLF Appearance
This is a pivotal, prospective active-controlled, randomized, double blinded (blinded evaluator and subject), intra-individual split-face comparison, non-inferiority study of DKL crosslinked sodium hyaluronate 23 versus Juvederm…
- Trial name
- NCT05021913
- Testing
- DKL crosslinked sodium hyaluronate 23, Juvéderm Volift™ with lidocaine (Allergan, Inc)
- Where
- Sweden
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Dr. Korman Laboratories Ltd.
HIV I Infection, HIV Associated Lipodystrophy
Neuroinflammation and Neurodegeneration in HIV-positive Subjects Switched and Initially Treated With INSTI
Since the HIV changed its course to the chronic disease, high incidence of metabolic syndrome both in HIV positive and negative subjects has become an issue.
- Conditions
- HIV I Infection, HIV Associated Lipodystrophy, Metabolic Syndrome, Aging
- Trial name
- NCT04887675
- Testing
- MRI
- Where
- Serbia
- Volunteers
- 120 people
- Sponsor
- University of Novi Sad
Visible Skin Aging Signs, Wrinkles and Folds in Lower Face
Efficacy of a Combined Oral and Topical Collagen Regimen Compared to Topical Collagen or Oral Collagen Regimens in Women With Skin Ageing Signs
This clinical study is conducted at one study site and in 165 women with visible signs of skin aging. It compares after 13 weeks the benefit of a combined oral collagen supplement and topical collagen serum regimen compared with…
- Conditions
- Visible Skin Aging Signs, Wrinkles and Folds in Lower Face, Skin Ageing, Skin Elasticity
- Trial name
- NCT07473037
- Testing
- Oral collagen, topical application of collagen serum
- Volunteers
- 165 people
- Sponsor
- Vichy Laboratoires
Skin Aging, Photoaging
Effects of Stabilized Retinaldehyde on Aging Skin: A Split-Face Study
The goal of this clinical trial is to learn if retinaldehyde cream improves the appearance of aging skin in women aged 30 to 60 years.
- Trial name
- NCT07510165
- Testing
- Stabilized retinaldehyde 0.1%, Stabilized retinaldehyde 0.05%
- Where
- Poland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Facial Aging, Wrinkles
Effect of Single Facial Acupuncture on Dermal Structure and Appearance Satisfaction
This study aims to investigate the effects of a single session of facial rejuvenation acupuncture on skin structure and personal satisfaction with facial appearance.
- Conditions
- Facial Aging, Wrinkles, Skin Aging
- Trial name
- FRA (NCT07664280)
- Testing
- Facial Rejuvenation Acupuncture (FRA)
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Far Eastern Memorial Hospital
Skin Quality, Lips Quality
Evaluation of the Effects of an Oral Supplementation Containing Hyaluronic Acid
This is a single center, double-blind, randomized, placebo-controlled study, performed on two parallel groups. A total of 130 adult female subjects meeting specific inclusion/exclusion criteria will be included in order to have…
- Conditions
- Skin Quality, Lips Quality, Persistence of the Effect
- Trial name
- NCT06774742
- Testing
- HAFS Supplementation
- Where
- France
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- TS Biotech - Shandong Tiansheng Biotechnology Co., Ltd
Brow Ptosis, Skin Aging
Single-Session Microfocused Ultrasound, AbobotulinumtoxinA and Temporal Hyaluronic Acid Filler for Non-Surgical Brow Lifting
This observational study describes the results of a routine aesthetic treatment for mild to moderate eyebrow drooping (brow ptosis).
- Conditions
- Brow Ptosis, Skin Aging, Facial Aging
- Trial name
- NCT07894822
- Testing
- Microfocused ultrasound with visualization, AbobotulinumtoxinA, Hyaluronic acid filler
- Where
- Russia
- Volunteers
- 36 people
- Sponsor
- Estelab Clinic