Pulpitis - IrreversibleDTNVNCT07297836
Professional Practices Regarding Treatment of Non-vital Primary Teeth Among Dental Surgeons in France
An observational study of Pulpitis - Irreversible and Pulp Necrosis, run by University Hospital, Strasbourg, France at 1 site in France.
Trial summary
When faced with primary teeth affected by irreversible pulpitis or pulp necrosis, extraction is often the preferred option for practitioners, although validated alternatives exist, notably pulpectomy, which has high success rates when performed correctly. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Pulpitis - Irreversible, Pulp Necrosis, Apical Periodontitis
- How many people
- 100 participants
- Where
- 1 siteFrance
- Study dates
- 7 Nov 2025to 7 Nov 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Dentist treating children
Who may be able to join
- Being a dentist treating children
Who cannot join
- Being a dentist treating children
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
Service de Médecine et Chirurgie Bucco-dentaires - CHU de Strasbourg - France
Strasbourg, 67091
François CLAUSS, DDS, PhD, 33 3 88 11 69 39, françois.clauss@chru-strasbourg.fr
Nhat Minh DO, DDS, 33 3 88 11 69 39, nhatminh.do@chru-strasbourg.fr
About this study
Official title: Description of Professional Practices Regarding Treatment of Non-vital Primary Teeth Among Dental Surgeons in France
When faced with primary teeth affected by irreversible pulpitis or pulp necrosis, extraction is often the preferred option for practitioners, although validated alternatives exist, notably pulpectomy, which has high success rates when performed correctly. Recommended by the American Academy of Pediatric Dentistry, this technique relies on rigorous disinfection and the use of materials adapted to natural exfoliation. Lesion sterilization tissue repair (LSTR), although more controversial due to the use of topical antibiotics, can also be considered in certain clinical situations. However, data on French practices in this area are very limited, hence the need to evaluate practitioners' treatment choices, their potential reservations, and the criteria guiding their decisions.
- Conditions
- Pulpitis - Irreversible, Pulp Necrosis, Apical Periodontitis
- Keywords
- Pulpectomy, Pulp necrosis, Primary teeth, Non-vital primary teeth, Irreversible pulpitis, Natural exfoliation, Lesion Sterilization, Tissue Repair, Topical antibiotics, Pulpitis - Irreversible, Apical Periodontitis
- Medical subject headings
- Dental Pulp Necrosis, Periapical Periodontitis
What is being measured
The primary outcome is the main question the study is designed to answer.
Description of professional practices regarding the treatment of non-vital primary teeth by dentists in France
There is no evaluation to be carried out in this study; It is just a matter of collecting and analyzing the professional practices of dental surgeons who treat children.
The professional practices of dentists are collected through an anonymous questionnaire.
Measured: Up to 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Dec 2025
- Study start7 Nov 2025
- Primary completionNov 2026 (estimated)
- Study completion7 Nov 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Pulpitis - IrreversibleStudies of the same condition, open and under way.
- More trials run by University Hospital, Strasbourg, FranceThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Prospective
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Hospital, Strasbourg, France
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07297836
- Sponsor's protocol ID
- 9765
- Acronym
- DTNV
- Status last verified
- Dec 2025
- First submitted
- 2 Dec 2025
- Last updated
- 3 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 3 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Description of Professional Practices Regarding Treatment of Non-vital Primary Teeth Among Dental Surgeons in France
- ClinicalTrials.gov ID
- NCT07297836
- Acronym / sponsor ID
- DTNV / 9765
- Conditions
- Pulpitis - Irreversible, Pulp Necrosis, Apical Periodontitis
- Keywords
- Pulpectomy, Pulp necrosis, Primary teeth, Non-vital primary teeth, Irreversible pulpitis, Natural exfoliation, Lesion Sterilization, Tissue Repair
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- University Hospital, Strasbourg, FranceUniversity, hospital or other
- Study start
- 7 Nov 2025 (actual)
- Primary completion
- Nov 2026 (estimated)
- Study completion
- 7 Nov 2026 (estimated)
- First posted
- 22 Dec 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
When faced with primary teeth affected by irreversible pulpitis or pulp necrosis, extraction is often the preferred option for practitioners, although validated alternatives exist, notably pulpectomy, which has high success rates when performed correctly. Recommended by the American Academy of Pediatric Dentistry, this technique relies on rigorous disinfection and the use of materials adapted to natural exfoliation. Lesion sterilization tissue repair (LSTR), although more controversial due to the use of topical antibiotics, can also be considered in certain clinical situations. However, data on French practices in this area are very limited, hence the need to evaluate practitioners' treatment choices, their potential reservations, and the criteria guiding their decisions.
Study design
- Observational model
- Case only
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Dentist treating children
Key inclusion criteria (1 listed)
- Being a dentist treating children
Key exclusion criteria (1 listed)
- Being a dentist treating children
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Description of professional practices regarding the treatment of non-vital primary teeth by dentists in France
Time frame: Up to 1 year
There is no evaluation to be carried out in this study; It is just a matter of collecting and analyzing the professional practices of dental surgeons who treat children. The professional practices of dentists are collected through an anonymous questionnaire.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Mar 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Pulpitis - Irreversible and Pulp Necrosis, run by University Hospital, Strasbourg, France at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 3 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact François CLAUSS, DDS, PhD (33 3 88 11 69 39, françois.clauss@chru-strasbourg.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Description of professional practices regarding the treatment of non-vital primary teeth by dentists in France (time frame: Up to 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Mar 2026.