Root Canal TherapyNCT07304869

Treatment Durations for Endodontic Procedures

An observational study of Root Canal Therapy, run by Uşak University at 1 site in Turkey (Türkiye).

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Trial summary

The aim of this observational study is to compare the treatment durations of different stages of routine root canal therapy performed on maxillary molar teeth using direct vision, magnification loupes, and a dental operating microscope. Read more about this study

Who is it for?: Ages 12 years and older
Conditions the study is for: Root Canal Therapy
How many people: 102 participants
Where: 1 siteTurkey (Türkiye)
Study dates: 1 Feb 2025to 31 Oct 2025
How long will I take part?: 1 Month
Phase: Observational
Are there results?: Yes, posted in the registrySummary in the doctors' view

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 12 years and older
All sexes
No healthy volunteers
Child, Adult, Older adult

Study population: Patients admitted to the Department of Endodontics, Faculty of Dentistry, Uşak University, who required root canal treatment of maxillary first molar teeth

Who may be able to join

Patients requiring root canal treatment of the maxillary first molar tooth

Who cannot join

Previous root canal treatment on the maxillary first molar tooth
Presence of fracture or crack in the maxillary first molar tooth
Lack of indication for completing treatment in a single session
Patient refusal to continue treatment during the procedure
Indication for extraction due to complications during treatment
Teeth indicated for fiber post restoration due to excessive material loss

Trial locations and contacts

1 site in 1 country.

Turkey (Türkiye)1 site

Uşak University Faculty of Dentistry, Department of Endodontics
Uşak, 64000

Other trials in Turkey (Türkiye)

About this study

Official title: Comparison of Treatment Durations for Endodontic Procedures on Maxillary Molar Teeth Using Different Magnification Techniques

The primary question the study seeks to answer is whether there is a significant difference in the duration of endodontic procedures performed under different magnification techniques.

Patients indicated for root canal treatment in their maxillary first molar teeth will receive standard root canal therapy in accordance with routine clinical protocols. The duration of each procedural step will be recorded and subsequently compared among the three magnification methods.

Read the detailed description

In this observational study, routine root canal treatment procedures will be performed in accordance with standard endodontic protocols on patients who applied to the Department of Endodontics, Faculty of Dentistry, Uşak University, and were indicated for root canal treatment on their maxillary first molar teeth.

The treatment procedures consist of seven main stages:
Preparation of the access cavity
Determination of the working length
Shaping of the root canals
Detection and shaping of the MB2 canal
Final irrigation and passive ultrasonic activation
Root canal filling

Application of the coronal restoration

All steps will be carried out according to standard clinical endodontic protocols under rubber dam isolation. The duration of each stage will be recorded individually.

Participants will be divided into three groups based on the magnification technique used during treatment:

Group 1: Treatments performed under direct vision

Group 2: Treatments performed using dental loupes

Group 3: Treatments performed using a dental operating microscope

All procedures in each group will follow the same standardized root canal treatment protocol, differing only in the magnification technique employed.

Conditions: Root Canal Therapy
Keywords: root canal treatment, Dental operating microscope, dental loupes, chair time, second mesiobuccal canal

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Study groups in NCT07304869
Study group	Role	What they receive
Patients treated under direct vision		Root canal treatment of maxillary first molar teeth performed without magnification, using direct visual inspection only.
Patients treated using dental loupes		Root canal treatment of maxillary first molar teeth performed using 5× magnification dental loupes.
Patients treated using a dental operating microscope		Root canal treatment of maxillary first molar teeth performed using a dental operating microscope at 8×-16× magnification.

What is being measured

The primary outcome is the main question the study is designed to answer.

Duration of Each Procedural Step in Endodontic Treatment
The duration (in seconds) of each of seven key procedural stages performed during routine root canal treatment on maxillary first molar teeth:
1. Access cavity preparation
2. Working length determination
3. Canal shaping
4. MB2 canal detection and shaping
5. Final irrigation and passive ultrasonic activation
6. Root canal obturation
7. Coronal Restoration
The duration of each stage was recorded separately. In addition, the sum of the durations of these seven stages was recorded as the total treatment time.
Each stage was timed separately for three groups (direct vision, dental loupes, and dental operating microscope) to compare the effect of different magnification techniques on working efficiency.
Measured: From the start of access cavity preparation to the completion of coronal restoration during a single treatment visit (approximately 35-120 minutes).

Secondary outcomes (1)

Presence of MB2 Canal According to Magnification Technique
The presence or absence of a second mesiobuccal (MB2) canal in maxillary first molar teeth will be recorded for each magnification group (direct vision, dental loupes, and dental operating microscope). The association between the magnification method and MB2 canal detection will be evaluated using the Chi-square test (Monte Carlo simulation).
Measured: Baseline (at the time of canal orifice identification)

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

1 Feb 202531 Oct 2025

First posted26 Dec 2025
Study start1 Feb 2025
Primary completion31 Oct 2025
Study completion31 Oct 2025

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
Publications (2)Papers the sponsor has linked to this study.
Other trials for Root Canal TherapyStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Observational
Observational model: Other
Time perspective: Cross-sectional
Enrolment: 102 participants (actual)
Target duration: 1 Month

IDs, dates and publications

ClinicalTrials.gov ID: NCT07304869
Sponsor's protocol ID: 558-558-07
Status last verified: Jul 2026
First submitted: 26 Nov 2025
Last updated: 24 Aug 2026
Results posted: Yes, on ClinicalTrials.gov
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No: The individual participant data collected in this study will not be shared with other researchers. Data will be used only for academic purposes within the scope of the thesis and institutional ethics approval.

Publications

Buhrley LJ, Barrows MJ, BeGole EA, Wenckus CS. Effect of magnification on locating the MB2 canal in maxillary molars. J Endod. 2002 Apr;28(4):324-7. doi: 10.1097/00004770-200204000-00016.
PubMed 12043874
Wong AW, Zhu X, Zhang S, Li SK, Zhang C, Chu CH. Treatment time for non-surgical endodontic therapy with or without a magnifying loupe. BMC Oral Health. 2015 Mar 20;15:40. doi: 10.1186/s12903-015-0025-7.
PubMed 25887978

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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All Root Canal Therapy trials

Study at a glance

From the registry record, last updated by the sponsor on 24 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Comparison of Treatment Durations for Endodontic Procedures on Maxillary Molar Teeth Using Different Magnification Techniques
ClinicalTrials.gov ID: NCT07304869
Acronym / sponsor ID: 558-558-07
Conditions: Root Canal Therapy
Keywords: root canal treatment, Dental operating microscope, dental loupes, chair time, second mesiobuccal canal
Study type: Observational
Recruitment status: Completed
Enrolment: 102 participants (actual)
Lead sponsor: Uşak UniversityUniversity, hospital or other
Study start: 1 Feb 2025 (actual)
Primary completion: 31 Oct 2025 (actual)
Study completion: 31 Oct 2025 (actual)
First posted: 26 Dec 2025 (actual)
Results: Posted 24 Aug 2026

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

The primary question the study seeks to answer is whether there is a significant difference in the duration of endodontic procedures performed under different magnification techniques.

Detailed description

The treatment procedures consist of seven main stages:
Preparation of the access cavity
Determination of the working length
Shaping of the root canals
Detection and shaping of the MB2 canal
Final irrigation and passive ultrasonic activation
Root canal filling

Application of the coronal restoration

All steps will be carried out according to standard clinical endodontic protocols under rubber dam isolation. The duration of each stage will be recorded individually.

Participants will be divided into three groups based on the magnification technique used during treatment:

Group 1: Treatments performed under direct vision

Group 2: Treatments performed using dental loupes

Group 3: Treatments performed using a dental operating microscope

All procedures in each group will follow the same standardized root canal treatment protocol, differing only in the magnification technique employed.

Study design

Observational model: Other
Time perspective: Cross-sectional
Target follow-up: 1 Month
Number of arms: 3

Arm	Type	Receives
Patients treated under direct vision	–	–Root canal treatment of maxillary first molar teeth performed without magnification, using direct visual inspection only.
Patients treated using dental loupes	–	–Root canal treatment of maxillary first molar teeth performed using 5× magnification dental loupes.
Patients treated using a dental operating microscope	–	–Root canal treatment of maxillary first molar teeth performed using a dental operating microscope at 8×-16× magnification.

Who may qualify

Ages: 12 years and older
Sex: All
Healthy volunteers: Not accepted
Age groups: Child, Adult, Older adult
Study population: Patients admitted to the Department of Endodontics, Faculty of Dentistry, Uşak University, who required root canal treatment of maxillary first molar teeth

Key inclusion criteria (1 listed)

Patients requiring root canal treatment of the maxillary first molar tooth

Key exclusion criteria (6 listed)

Previous root canal treatment on the maxillary first molar tooth
Presence of fracture or crack in the maxillary first molar tooth
Lack of indication for completing treatment in a single session
Patient refusal to continue treatment during the procedure
Indication for extraction due to complications during treatment

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Primary outcome

Duration of Each Procedural Step in Endodontic Treatment
Time frame: From the start of access cavity preparation to the completion of coronal restoration during a single treatment visit (approximately 35-120 minutes).
The duration (in seconds) of each of seven key procedural stages performed during routine root canal treatment on maxillary first molar teeth: 1. Access cavity preparation 2. Working length determination 3. Canal shaping 4. MB2 canal detection and shaping 5. Final irrigation and passive ultrasonic activation 6. Root canal obturation 7. Coronal Restoration The duration of each stage was recorded separately. In addition, the sum of the durations of these seven stages was recorded as the total treatment time. Each stage was timed separately for three groups (direct vision, dental loupes, and dental operating microscope) to compare the effect of different magnification techniques on working efficiency.

1 secondary outcome

Presence of MB2 Canal According to Magnification Technique
Time frame: Baseline (at the time of canal orifice identification)

Results and safety

Results posted to the registry on 24 Aug 2026, as reported by the sponsor. Figures are copied from the record, not re-analysed. Full results on ClinicalTrials.gov.

Participant flow

Group	Started	Completed
Direct Vision	34	34
Dental Loupe	34	34
Dental Operating Microscope	34	34

Primary outcome: Duration of Each Procedural Step in Endodontic Treatment

Time frame: From the start of access cavity preparation to the completion of coronal restoration during a single treatment visit (approximately 35-120 minutes).. Median (Inter-Quartile Range). Unit: seconds

Measure	Patients Treated Under Direct Vision n = 34	Patients Treated Using Dental Loupes n = 34	Patients Treated Using a Dental Operating Microscope n = 34
1. Access cavity preparation	186 (93 to 417)	287 (131 to 572)	489.5 (302 to 1157)
2. Working length determination	152 (63 to 682)	259 (112 to 662)	240 (132 to 648)
3. Canal shaping	483 (235 to 900)	570 (259 to 1500)	606.5 (393 to 1153)
4. MB2 canal detection and shaping	311 (202 to 780)	483.5 (240 to 954)	546 (313 to 1200)
5. Final irrigation and passive ultrasonic activation	590.5 (350 to 840)	644.5 (507 to 1047)	720 (583 to 1080)
6. Root canal obturation	420 (103 to 600)	580 (345 to 1200)	618.5 (415 to 1500)
7. Coronal Restoration	601.5 (360 to 1980)	900 (418 to 3300)	1394 (396 to 3000)
Total treatment time	2767.5 (2037 to 4830)	3912.5 (2716 to 7080)	4751 (3633 to 6840)

Patients Treated Under Direct Vision vs Patients Treated Using Dental Loupes vs Patients Treated Using a Dental Operating Microscope: p <0.001, Kruskal-Wallis

1 secondary outcome is reported in the full results.

Adverse events

Time frame: From the start of access cavity preparation to the completion of coronal restoration during a single treatment visit (approximately 35-120 minutes). Other adverse events reported at 0% frequency or more

Group	Serious adverse events	Other adverse events	Deaths
Patients Treated Under Direct Vision	0 of 34 (0%)	0 of 34 (0%)	0 of 34
Patients Treated Using Dental Loupes	0 of 34 (0%)	0 of 34 (0%)	0 of 34
Patients Treated Using a Dental Operating Microscope	0 of 34 (0%)	0 of 34 (0%)	0 of 34

Limitations and caveats (from the sponsor): Several limitations of this study should be considered. All procedures were performed by a single operator, and the operator's limited experience with the dental operating microscope may have contributed to longer procedure times, particularly in the microscope group. Procedure time is influenced by multiple factors, including clinical conditions, tooth anatomy, operator-related variables, and patient-related factors, which may limit the generalizability of the findings.

Loading the posted results from ClinicalTrials.gov…

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 24 Aug 2026.
Posted resultsParticipant flow, baseline, all outcome measures and adverse events.
Background: PubMed 12043874Buhrley LJ, Barrows MJ, BeGole EA, Wenckus CS. Effect of magnification on locating the MB2 canal in maxillary molars. J Endod. 2002 Apr;28(4):324-7. doi: 10.1097/00004770-200204000-00016.
Background: PubMed 25887978Wong AW, Zhu X, Zhang S, Li SK, Zhang C, Chu CH. Treatment time for non-surgical endodontic therapy with or without a magnifying loupe. BMC Oral Health. 2015 Mar 20;15:40. doi: 10.1186/s12903-015-0025-7.
Individual participant dataSharing planned: No. The individual participant data collected in this study will not be shared with other researchers. Data will be used only for academic purposes within the scope of the thesis and institutional ethics approval.

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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Oğuz Tavşan, Assistant Professor principal investigator

Uşak University Faculty of Dentistry, Department of Endodontics

Tuğçe N Çağlar, Research Assistant study director

Uşak University Faculty of Dentistry, Department of Endodontics

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

An observational study of Root Canal Therapy, run by Uşak University at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 24 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

Yes. Results are posted in the registry (first posted 24 Aug 2026). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Duration of Each Procedural Step in Endodontic Treatment (time frame: From the start of access cavity preparation to the completion of coronal restoration during a single treatment visit (approximately 35-120 minutes).). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07304869, which also lists 2 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Aug 2026.