Sarcopenia in ElderlyNCT07315789
Effects of a Strength Training Programme in Institutionalized Older Adults With Sarcopenia.
A study testing High-intensity interval strength training: therapeutic exercise programme. in people with Sarcopenia in Elderly and Institutionalized Older Adults, run by University of Extremadura at 1 site in Spain.
Trial summary
Sarcopenia is one of the main problems in the elderly population. The concept of disease has evolved, as have its treatment strategies. Among these is high-intensity interval training (HIIT). Read more about this study
- Who is it for?
- Ages 60 years and older
- Conditions the study is for
- Sarcopenia in Elderly, Institutionalized Older Adults, HIIT
- What is being tested?
- High-intensity interval strength training: therapeutic exercise programme.
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 164 participants
- Where
- 1 siteSpain
- Study dates
- 1 Feb 2022to 15 Dec 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 60 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- older adults who have been institutionalized for at least one year
- older adults who are institutionalized with clinical suspicion of sarcopenia according to the Sarc-F questionnaire and muscle strength criteria
- older adults residing in the community of Extremadura.
Who cannot join
- present cognitive impairment (score <24 Mini-Mental State Examination)
- primary, serious, or chronic diseases that could explain the decrease in muscle strength and the other diagnostic variables of the participants
- diseases or physical disorders that hinder the assessment of the participants; -use of drugs that may affect muscle strength and mass.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of a High-intensity Interval Strength Training Programme in Institutionalized Older Adults With Sarcopenia: a Randomized Clinical Trial.
Sarcopenia is one of the main problems in the elderly population. The concept of disease has evolved, as have its treatment strategies. Among these is high-intensity interval training (HIIT). This approach has been little studied in older adults with sarcopenia, especially in institutionalized older adults in nursing homes. So this will be the objective of the study. A randomised clinical trial is being conducted to analyse how these diagnostic criteria for sarcopenia evolve after the application of HIIT compared to a control group.
- Conditions
- Sarcopenia in Elderly, Institutionalized Older Adults, HIIT
- Being tested
- High-intensity interval strength training: therapeutic exercise programme.
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
High-intensity interval strength training: therapeutic exercise programme.Other
A 12-week high-intensity interval strenght training (HIITs) programme is developed with basic exercises adapted to the living environment of older people. Progress in the exercises over the twelve weeks is measured using the maximum weight that can be lifted in one repetition (1-RM), maximum heart rate (MHR) and the Borg scale.
| Study group | Role | What they receive |
|---|---|---|
| This group includes institutionalized older adults aged 60 and over for treatment. | Experimental | Not described Receives: Other: High-intensity interval strength training: therapeutic exercise programme. |
| This group includes institutionalized older adults aged 60 and over. | No intervention | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Hand grip strenght
The researchers used the JAMAR dynamometer
Measured: Thrice at the baseline: at the start, at 8 weeks and at 12 weeks.
Secondary outcomes (3)
Muscular mass / appendicular skeletal mass (ASM)
The researchers used bioimpedance analysis with Tanita MC780-S MA Multifrequency.
Measured: Thrice at the baseline: at the start, at 8 weeks and at 12 weeks.
Physical performance
The researchers used the scale: "Short Physical Performance Battery" (SPPB).
Measured: Thrice at the baseline: at the start, at 8 weeks and at 12 weeks.
Physical performance 2
The researchers used the test: "Timed Up and Go" (TUG).
Measured: Thrice at the baseline: at the start, at 8 weeks and at 12 weeks.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted2 Jan 2026
- Study start1 Feb 2022
- Primary completion15 Dec 2025
- Study completion15 Dec 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Sarcopenia in ElderlyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 164 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Extremadura
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Jesús Zapata Linares, University of Extremadura
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07315789
- Sponsor's protocol ID
- 02
- Status last verified
- Mar 2026
- First submitted
- 10 Dec 2025
- Last updated
- 17 Mar 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of a High-intensity Interval Strength Training Programme in Institutionalized Older Adults With Sarcopenia: a Randomized Clinical Trial.
- ClinicalTrials.gov ID
- NCT07315789
- Acronym / sponsor ID
- 02
- Conditions
- Sarcopenia in Elderly, Institutionalized Older Adults, HIIT
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 164 participants (actual)
- Lead sponsor
- University of ExtremaduraUniversity, hospital or other
- Study start
- 1 Feb 2022 (actual)
- Primary completion
- 15 Dec 2025 (actual)
- Study completion
- 15 Dec 2025 (actual)
- First posted
- 2 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Sarcopenia is one of the main problems in the elderly population. The concept of disease has evolved, as have its treatment strategies. Among these is high-intensity interval training (HIIT). This approach has been little studied in older adults with sarcopenia, especially in institutionalized older adults in nursing homes. So this will be the objective of the study. A randomised clinical trial is being conducted to analyse how these diagnostic criteria for sarcopenia evolve after the application of HIIT compared to a control group.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| This group includes institutionalized older adults aged 60 and over for treatment. | Experimental | Other: High-intensity interval strength training: therapeutic exercise programme. |
| This group includes institutionalized older adults aged 60 and over. | No intervention | – |
Who may qualify
- Ages
- 60 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- older adults who have been institutionalized for at least one year
- older adults who are institutionalized with clinical suspicion of sarcopenia according to the Sarc-F questionnaire and muscle strength criteria
- older adults residing in the community of Extremadura.
Key exclusion criteria (3 listed)
- present cognitive impairment (score <24 Mini-Mental State Examination)
- primary, serious, or chronic diseases that could explain the decrease in muscle strength and the other diagnostic variables of the participants
- diseases or physical disorders that hinder the assessment of the participants; -use of drugs that may affect muscle strength and mass.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| High-intensity interval strength training: therapeutic exercise programme.A 12-week high-intensity interval strenght training (HIITs) programme is developed with basic exercises adapted to the living environment of older people. Progress in the exercises over the twelve weeks is measured using the maximum weight that can be lifted in one repetition (1-RM), maximum heart rate (MHR) and the Borg scale. | Other | This group includes institutionalized older adults aged 60 and over for treatment. |
Primary outcome
Hand grip strenght
Time frame: Thrice at the baseline: at the start, at 8 weeks and at 12 weeks.
The researchers used the JAMAR dynamometer
3 secondary outcomes
Muscular mass / appendicular skeletal mass (ASM)
Time frame: Thrice at the baseline: at the start, at 8 weeks and at 12 weeks.
Physical performance
Time frame: Thrice at the baseline: at the start, at 8 weeks and at 12 weeks.
Physical performance 2
Time frame: Thrice at the baseline: at the start, at 8 weeks and at 12 weeks.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Mar 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing High-intensity interval strength training: therapeutic exercise programme. in people with Sarcopenia in Elderly and Institutionalized Older Adults, run by University of Extremadura at 1 site in Spain.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 17 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Spain. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Hand grip strenght (time frame: Thrice at the baseline: at the start, at 8 weeks and at 12 weeks.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Mar 2026.