Clinical trials: Sarcopenia in Elderly
Gastrointestinal Cancers, Frailty
Longitudinal Geriatric Vulnerability, Chemotherapy Toxicity, and Functional Outcomes in Older Adults With Gastrointestinal Cancer
Older adults with gastrointestinal cancers may be more likely to experience side effects from chemotherapy and difficulties with everyday activities. These problems are not always explained by age alone.
- Conditions
- Gastrointestinal Cancers, Frailty, Sarcopenia in Elderly, Malnutrition Elderly
- Trial name
- VITAL-GI (NCT07184047)
- Testing
- Standard-of-Care Systemic Chemotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Ankara Etlik City Hospital
Cancer Abdomen, Elderly (People Aged 65 or More)
Functional Decline and Quality of Life After Gastrointestinal Cancer Surgery in Older Adults
This prospective cohort study will evaluate functional decline, health-related quality of life, and long-term oncological outcomes in adults aged 65 years and older undergoing curative-intent resective surgery for…
- Conditions
- Cancer Abdomen, Elderly (People Aged 65 or More), Quality of Life, Sarcopenia in Elderly
- Trial name
- NCT07412379
- Where
- Colombia
- Volunteers
- 590 people
- Sponsor
- Hospital Universitario Mayor Méderi
Sarcopenia in Elderly
The Effect of Adding Elastic Resistance Training in Routine Physical Exercise on Walking Speed of Elderly People With Sarcopenia in Griya Wreda Jambangan, Surabaya
The goal of this randomized clinical trial is to learn whether adding elastic resistance training (ERT) to routine physical exercise can improve walking speed in older adults aged 60 years or older with sarcopenia living at Griya…
- Trial name
- NCT07859969
- Testing
- Elastic Resistance Training, Routine Physical Exercise
- Where
- Indonesia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Dr. Soetomo General Hospital
Sarcopenia in Elderly
Blood Flow Restriction Training in Acute Geriatric Rehabilitation
Background: Older adults have a reduced ability to build and maintain muscle mass due to age-related changes in the muscular system.
- Trial name
- NCT07291765
- Testing
- Stationary Bike + Blood-Flow-Restriction, Acute geriatric rehabilitation + No additional Intervention
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- University Hospital, Bonn
Sarcopenia in Elderly, Hospital Associated Disability
Preventing Hospital Associated Disability in Older Patients: Individualized Nutrition and Exercise Strategy
Aproximately a third of persons older than 70 years lose physical function and ability to take care of themselves during a stay at a hospital. This is associated to an increased risk of readmission and mortality.
- Conditions
- Sarcopenia in Elderly, Hospital Associated Disability, Malnutrition Elderly, Physical Function
- Trial name
- PrevHAD RCT (NCT07373587)
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 360 people
- Sponsor
- Bispebjerg Hospital
Sarcopenia, Sarcopenia in Elderly
Effects of Aquatic Exercise in Older Adults With Sarcopenia:A Randomized Trial
Sarcopenia is a geriatric syndrome characterized by age-related loss of skeletal muscle mass, strength, and physical performance, leading to increased risk of falls, functional decline, and reduced quality of life.
- Trial name
- NCT07575958
- Testing
- Aquatic Exercise Program, Home Exercise Program
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Sarcopenia in Elderly
Tai Chi Exercise to Improve Quality of Life and Depression in Elderly With Sarcopenia
This study aims to evaluate the effects of Tai Chi exercise on quality of life and depressive symptoms in elderly with sarcopenia.
- Trial name
- NCT07831356
- Testing
- Tai Chi Exercise, Elderly exercise (senam lansia)
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Hasanuddin University
Sarcopenia in Elderly
RANK-ligand Inhibition to Combat Sarcopenia With Underlying Osteoporosis
The objective of this study was to conduct a randomized, double-blind, double-dummy active controlled trial to determine the efficacy of denosumab in treating sarcopenia with underlying osteoporosis.
- Trial name
- NCT06643780
- Testing
- Denosumab, Zolendronic Acid
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Sarcopenia in Elderly
Tai Chi Exercise to Improve Physical Capabilities in Elderly With Sarcopenia
This study aims to evaluate the effects of Tai Chi exercise on the physical performance of elderly individuals diagnosed with sarcopenia.
- Trial name
- NCT07826000
- Testing
- Tai Chi Exercise, Elderly Gymnastics (Senam Lansia) Exercise
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Hasanuddin University
Sarcopenia in Elderly
RANKL Inhibition to Combat Sarcopenia in Hip Fracture Patients
The objective of this study is to conduct a pragmatic, randomized, double-blind, active-controlled trial to assess the efficacy of receptor activator of nuclear factor-kB ligand (RANKL) inhibition in the treatment of sarcopenia…
- Trial name
- NCT07056478
- Testing
- Denosumab (Prolia), Zoledronic acide (Aclasta)
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong
Sarcopenia in Elderly, Osteoarthritis (OA)
Impact of Pre-operative Sarcopenia on Functional Recovery After Hip Arthroplasty in Older Adults
This single-centre, exploratory study at Montpellier University Hospital will investigate whether having low muscle mass and strength before hip-replacement surgery, a condition called sarcopenia, impact the return to everyday…
- Conditions
- Sarcopenia in Elderly, Osteoarthritis (OA), Hip Fracture Surgeries
- Trial name
- HIP-REGEN (NCT07429955)
- Testing
- Total hip replacement, Blood sampling, Muscle biopsies
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Aging, Muscle Atrophy or Weakness
C-Protein in Fatigue and Aging
This study is investigating changes to the proteins in skeletal muscle that contribute to reduced muscle size and muscle function that occurs with aging.
- Conditions
- Aging, Muscle Atrophy or Weakness, Sarcopenia in Elderly, Sarcopenia
- Trial name
- NCT05926219
- Testing
- Fatiguing Exercise
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Oregon
Sarcopenia, Sarcopenia in Elderly
The Effect of Volunteer-Engaged Lifestyle Optimisation Via ICOPE on Sarcopenia in Older Adults (VELO-S)
Sarcopenia prevention and management are highly prioritised goals in the Healthy Ageing agenda. The study aims to: 1) evaluate the effects of the digital-enhanced, volunteer-engaged collaborative care pathway to improve…
- Conditions
- Sarcopenia, Sarcopenia in Elderly, Fall Prevention in Healthy Aging, Frailty Syndrome
- Trial name
- NCT07345832
- Testing
- Volunteer-Engaged Lifestyle Optimisation via ICOPE for Sarcopenia program (VELO-S), Attention control
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Sarcopenia in Elderly
Feasibility of Egg White Pudding Supplementation for Individuals in Personal Care Home Centres Needing Dietary Supplementation
This trial is an open-label randomized controlled parallel arm feasibility trial. 54 residents in care homes receiving nutrition supplementation (minimum 40% of each sex, ≥ 50 years of age).
- Trial name
- NCT07805993
- Testing
- Egg White Pudding, Nestle Resource
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Seven Oaks Hospital Chronic Disease Innovation Centre
Aging, Sarcopenia
Effects of a Buriti Supplement on Body Composition and Function in Older Adults
Aging is a natural process commonly associated with loss of muscle mass, reduced flexibility, and impaired balance, directly affecting the quality of life of older adults.
- Conditions
- Aging, Sarcopenia, Malnutrition Elderly
- Trial name
- NCT07716839
- Testing
- Nutricer® Supplementation, Tai Chi Chuan program
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Frailty, Sarcopenia
Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery
The goal of this observational study is to learn if simple tests for frailty and muscle strength can help predict which older adults (age 65 and older) are at higher risk for problems after major abdominal surgery.
- Conditions
- Frailty, Sarcopenia, Sarcopenia in Elderly, Muscle Strength
- Trial name
- NCT06988176
- Testing
- Frailty assessment, nutrition assessment, cognition assessment, muscle strength testing
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of North Carolina, Chapel Hill
Fatigue, Lactate
Lactate Kinetics After Multimodal Exercise and Adjunctive Virtual Reality Exercise in Hospitalized Geriatric Patients
The goal of this clinical trial is to determine whether adding virtual reality exercise to conventional multimodal exercise affects exercise-related lactate kinetics, functional status, frailty, sarcopenia risk, perceived…
- Conditions
- Fatigue, Lactate, Frailty, Sarcopenia in Elderly
- Trial name
- NCT07149272
- Testing
- Virtual Reality Exercise (VRE) using VRAGMENT software
- Where
- Indonesia
- Volunteers
- 153 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Sarcopenia in Elderly
Feasibility of Pre-Conditioning FRT in Sarcopenia
This study aims to assess whether a short, structured exercise programme is suitable and acceptable for older adults with early-stage muscle weakness (known as probable sarcopenia).
- Trial name
- NCT07756762
- Testing
- Pre-Conditioning Functional Resistance Exercise Program
- Volunteers
- 30 people
- Sponsor
- University of Hull
Sarcopenia in Elderly, Chronic Heart Failure
Effects of Resistance Training on Sarcopenia in Older Patients With Chronic Heart Failure
The goal of study is to evaluate the effects of an eight-week machine-based resistance training program on managing sarcopenia in older outpatients with chronic heart failure (HF) at Military Hospital 175.
- Trial name
- NCT06785168
- Testing
- Machine-based Resistance Training
- Where
- 2 sites in Vietnam
- Volunteers
- 146 people
- Sponsor
- Kieu Dang Phuong Nguyen
Sarcopenia in Elderly, Sarcopenia
A Study of AMC6156 in People With Sarcopenia
This clinical trial aims to find out whether AMC6156 can improve physical function and is safe in older adults with sarcopenia. Participants will take AMC6156 or a placebo daily for 12 weeks, and their movement, strength, and…
- Trial name
- NCT07072195
- Testing
- AMC6156 0.1mg, AMC6156 0.3mg, AMC6156 1.0mg
- Where
- 4 sites in South Korea
- Volunteers
- 80 people
- Sponsor
- Animuscure Inc.