Ischemic StrokeNCT07326410
Prevalence of Cerebral Large Vessel Occlusion Among Acute Ischemic Stroke Patients in Assiut University Hospitals
An observational study of Ischemic Stroke, run by Assiut University.
Trial summary
Prevalence of Large Vessel Occlusion among acute ischemic stroke patients in Assiut University hospitals 1. Study Objectives Primary Objective: To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals Secondary Objectives: To describe clinical and… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Ischemic Stroke
- How many people
- 300 participants
- Where
- No sites listed yet
- Study dates
- 1 Feb 2026to 1 Mar 2027
- How long will I take part?
- 2 Days
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Large Vessel Occlusion (LVO) defined as occlusion in: * Intracranial ICA * M1 or proximal M2 segments of MCA * Basilar artery ± Optional: A1 Clinical Data: * Demographics (age, sex) * Risk factors (HTN, DM, AF, CAD, smoking) * NIHSS on admission and discharge mRS on admission and discharge * Onset-to-door time * Imaging modality used Imaging Data: * Site of occlusion * ASPECTS (optional) * Collateral status (optional if available) Hospital Data: * Facility type (public vs private) * Door-to-CT and door-to-CTA times
Who may be able to join
- Adults (≥18 years)
- Diagnosed with acute ischemic stroke within 24 hours of symptom onset
- Underwent vascular imaging (CTA or MRA) on admission
Who cannot join
- Hemorrhagic stroke
- Stroke mimics
- Incomplete imaging data
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Prevalence of Large Vessel Occlusion among acute ischemic stroke patients in Assiut University hospitals
- Study Objectives Primary Objective:
Read more
- To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals Secondary Objectives:
- To describe clinical and radiological characteristics of LVO patients.
- To assess factors associated with LVO (age, sex, stroke severity, comorbidities).
- Study Design
- Type: single center, prospective observational cross-sectional study
- Duration: 12-month recruitment period
- Setting: Assiut university hospitals, stroke unit.
- Study Population
Inclusion Criteria:
- Adults (≥18 years)
- Diagnosed with acute ischemic stroke within 24 hours of symptom onset
- Underwent vascular imaging (CTA or MRA) on admission
Exclusion Criteria:
- Hemorrhagic stroke
- Stroke mimics
- Incomplete imaging data 4. Definitions
Large Vessel Occlusion (LVO) defined as occlusion in:
- Intracranial ICA
- M1 or proximal M2 segments of MCA
- Basilar artery ± Optional: A1 6. Data Collection
Clinical Data:
- Demographics (age, sex)
- Risk factors (HTN, DM, AF, CAD, smoking)
- NIHSS on admission and discharge mRS on admission and discharge
- Onset-to-door time
- Imaging modality used
Imaging Data:
- Site of occlusion
- ASPECTS (optional)
- Collateral status (optional if available)
Hospital Data:
- Facility type (public vs private)
- Door-to-CT and door-to-CTA times 8. Analysis Plan
- Primary: Prevalence of LVO = Number of LVO cases / Total AIS patients with vascular imaging
- Subgroup analysis: By age group, sex, region, NIHSS
- Secondary: Logistic regression to identify predictors of LVO
Read the detailed description
Prevalence of Large Vessel Occlusion among acute ischemic stroke patients in Assiut University hospitals
- Study Objectives Primary Objective:
- To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals Secondary Objectives:
- To describe clinical and radiological characteristics of LVO patients.
- To assess factors associated with LVO (age, sex, stroke severity, comorbidities).
- Study Design
- Type: single center, prospective observational cross-sectional study
- Duration: 12-month recruitment period
- Setting: Assiut university hospitals, stroke unit.
- Study Population
Inclusion Criteria:
- Adults (≥18 years)
- Diagnosed with acute ischemic stroke within 24 hours of symptom onset
- Underwent vascular imaging (CTA or MRA) on admission
Exclusion Criteria:
- Hemorrhagic stroke
- Stroke mimics
- Incomplete imaging data 4. Definitions
Large Vessel Occlusion (LVO) defined as occlusion in:
- Intracranial ICA
- M1 or proximal M2 segments of MCA
- Basilar artery ± Optional: A1 6. Data Collection
Clinical Data:
- Demographics (age, sex)
- Risk factors (HTN, DM, AF, CAD, smoking)
- NIHSS on admission and discharge mRS on admission and discharge
- Onset-to-door time
- Imaging modality used
Imaging Data:
- Site of occlusion
- ASPECTS (optional)
- Collateral status (optional if available)
Hospital Data:
- Facility type (public vs private)
- Door-to-CT and door-to-CTA times 8. Analysis Plan
- Primary: Prevalence of LVO = Number of LVO cases / Total AIS patients with vascular imaging
- Subgroup analysis: By age group, sex, region, NIHSS
- Secondary: Logistic regression to identify predictors of LVO
- Conditions
- Ischemic Stroke
- Keywords
- Prevalence of cerebral Large Vessel Occlusion among acute ischemic stroke patients
- Medical subject headings
- Ischemic Stroke
What is being measured
The primary outcome is the main question the study is designed to answer.
To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals
Prevalence of LVO = Number of LVO cases / Total AIS patients with vascular imaging
Measured: 12 months
Secondary outcomes (1)
-To describe clinical and radiological characteristics of LVO patients. - To assess factors associated with LVO (age, sex, stroke severity, comorbidities).
Subgroup analysis: By age group, sex, region, NIHSS
Measured: 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Jan 2026
- Study start1 Feb 2026 (estimated)
- Primary completion1 Feb 2027 (estimated)
- Study completion1 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Ischemic StrokeStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 300 participants (estimated)
- Target duration
- 2 Days
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmad Tarek Aly Sayed, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07326410
- Sponsor's protocol ID
- Prevalence of Cerebral LVO
- Status last verified
- Sep 2025
- First submitted
- 8 Dec 2025
- Last updated
- 8 Jan 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Financial issues
Study at a glance
From the registry record, last updated by the sponsor on 8 Jan 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prevalence of Cerebral Large Vessel Occlusion Among Acute Ischemic Stroke Patients in Assiut University Hospitals
- ClinicalTrials.gov ID
- NCT07326410
- Acronym / sponsor ID
- Prevalence of Cerebral LVO
- Conditions
- Ischemic Stroke
- Keywords
- Prevalence of cerebral Large Vessel Occlusion among acute ischemic stroke patients
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 300 participants (estimated)
- Lead sponsor
- Assiut UniversityUniversity, hospital or other
- Study start
- 1 Feb 2026 (estimated)
- Primary completion
- 1 Feb 2027 (estimated)
- Study completion
- 1 Mar 2027 (estimated)
- First posted
- 8 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Prevalence of Large Vessel Occlusion among acute ischemic stroke patients in Assiut University hospitals
- Study Objectives Primary Objective:
- To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals Secondary Objectives:
- To describe clinical and radiological characteristics of LVO patients.
- To assess factors associated with LVO (age, sex, stroke severity, comorbidities).
- Study Design
- Type: single center, prospective observational cross-sectional study
- Duration: 12-month recruitment period
- Setting: Assiut university hospitals, stroke unit.
- Study Population
Inclusion Criteria:
- Adults (≥18 years)
- Diagnosed with acute ischemic stroke within 24 hours of symptom onset
- Underwent vascular imaging (CTA or MRA) on admission
Exclusion Criteria:
- Hemorrhagic stroke
- Stroke mimics
- Incomplete imaging data 4. Definitions
Large Vessel Occlusion (LVO) defined as occlusion in:
- Intracranial ICA
- M1 or proximal M2 segments of MCA
- Basilar artery ± Optional: A1 6. Data Collection
Clinical Data:
- Demographics (age, sex)
- Risk factors (HTN, DM, AF, CAD, smoking)
- NIHSS on admission and discharge mRS on admission and discharge
- Onset-to-door time
- Imaging modality used
Imaging Data:
- Site of occlusion
- ASPECTS (optional)
- Collateral status (optional if available)
Hospital Data:
- Facility type (public vs private)
- Door-to-CT and door-to-CTA times 8. Analysis Plan
- Primary: Prevalence of LVO = Number of LVO cases / Total AIS patients with vascular imaging
- Subgroup analysis: By age group, sex, region, NIHSS
- Secondary: Logistic regression to identify predictors of LVO
Detailed description
Prevalence of Large Vessel Occlusion among acute ischemic stroke patients in Assiut University hospitals
- Study Objectives Primary Objective:
- To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals Secondary Objectives:
- To describe clinical and radiological characteristics of LVO patients.
- To assess factors associated with LVO (age, sex, stroke severity, comorbidities).
- Study Design
- Type: single center, prospective observational cross-sectional study
- Duration: 12-month recruitment period
- Setting: Assiut university hospitals, stroke unit.
- Study Population
Inclusion Criteria:
- Adults (≥18 years)
- Diagnosed with acute ischemic stroke within 24 hours of symptom onset
- Underwent vascular imaging (CTA or MRA) on admission
Exclusion Criteria:
- Hemorrhagic stroke
- Stroke mimics
- Incomplete imaging data 4. Definitions
Large Vessel Occlusion (LVO) defined as occlusion in:
- Intracranial ICA
- M1 or proximal M2 segments of MCA
- Basilar artery ± Optional: A1 6. Data Collection
Clinical Data:
- Demographics (age, sex)
- Risk factors (HTN, DM, AF, CAD, smoking)
- NIHSS on admission and discharge mRS on admission and discharge
- Onset-to-door time
- Imaging modality used
Imaging Data:
- Site of occlusion
- ASPECTS (optional)
- Collateral status (optional if available)
Hospital Data:
- Facility type (public vs private)
- Door-to-CT and door-to-CTA times 8. Analysis Plan
- Primary: Prevalence of LVO = Number of LVO cases / Total AIS patients with vascular imaging
- Subgroup analysis: By age group, sex, region, NIHSS
- Secondary: Logistic regression to identify predictors of LVO
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Target follow-up
- 2 Days
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Large Vessel Occlusion (LVO) defined as occlusion in: * Intracranial ICA * M1 or proximal M2 segments of MCA * Basilar artery ± Optional: A1 Clinical Data: * Demographics (age, sex) * Risk factors (HTN, DM, AF, CAD, smoking) * NIHSS on admission and discharge mRS on admission and discharge * Onset-to-door time * Imaging modality used Imaging Data: * Site of occlusion * ASPECTS (optional) * Collateral status (optional if available) Hospital Data: * Facility type (public vs private) * Door-to-CT and door-to-CTA times
Key inclusion criteria (3 listed)
- Adults (≥18 years)
- Diagnosed with acute ischemic stroke within 24 hours of symptom onset
- Underwent vascular imaging (CTA or MRA) on admission
Key exclusion criteria (3 listed)
- Hemorrhagic stroke
- Stroke mimics
- Incomplete imaging data
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals
Time frame: 12 months
Prevalence of LVO = Number of LVO cases / Total AIS patients with vascular imaging
1 secondary outcome
-To describe clinical and radiological characteristics of LVO patients. - To assess factors associated with LVO (age, sex, stroke severity, comorbidities).
Time frame: 12 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Jan 2026.
- Prevalence of cerebral Large Vessel Occlusion among acute ischemic strokeLink provided by the sponsor.
- Individual participant dataSharing planned: No. Financial issues
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
An observational study of Ischemic Stroke, run by Assiut University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 8 Jan 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ahmed Nasr Professor of neurology, Professor (+201009949677, d_ahmednasr@yahoo.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
To determine the prevalence of LVO among acute ischemic stroke (AIS) patients presenting to Assiut University hospitals (time frame: 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Jan 2026.