Vital Pulp Therapy in Primary TeethNCT07333872
Evaluation of Pulpotomy, Partial Pulpotomy, and Direct Pulp Capping Using Mineral Trioxide Aggregate.
A study testing pulp capping with MTA in people with Vital Pulp Therapy in Primary Teeth, run by Delta University for Science and Technology at 1 site in Egypt.
Trial summary
A comparative evaluation for three vital pulp therapy techniques in primary molars using the same material (MTA) Read more about this study
- Who is it for?
- Ages 4 to 7 years
- Conditions the study is for
- Vital Pulp Therapy in Primary Teeth
- What is being tested?
- pulp capping with MTA
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 96 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jun 2025to 9 Jun 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 4 to 7 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- articipants were cooperative children (4-7 years) with no systemic diseases or relevant allergies. Eligible teeth were restorable primary second molars with deep carious lesions and a diagnosis of reversible pulpitis,
Who cannot join
- spontaneous pain, edema, fistula, pathological mobility, or percussion sensitivity.
Trial locations and contacts
1 site in 1 country.
Egypt1 site
Delta university for science and technology
Gamasa, Dakahlia Governorate, 35516
About this study
Official title: Evaluation of Pulpotomy, Partial Pulpotomy, and Direct Pulp Capping Using Mineral Trioxide Aggregate in Primary Molars. A Randomized Clinical Trial.
A comparative evaluation for three vital pulp therapy techniques in primary molars using the same material (MTA)
- Conditions
- Vital Pulp Therapy in Primary Teeth
- Being tested
- pulp capping with MTA
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
pulp capping with MTAProcedure or surgery
Capping of the pulp tissue with a biocompatible material (MTA)
| Study group | Role | What they receive |
|---|---|---|
| Direct pulp capping | Experimental | Technique of vital pulp therapy to cap pin point exposure Receives: Procedure: pulp capping with MTA |
| Partial pulpotomy | Experimental | Technique of vital pulp therapy to cap widened pulp exposure Receives: Procedure: pulp capping with MTA |
| Pulpotomy | Experimental | Technique of vital pulp therapy of capping radicular pulp after removal of coronal pulp Receives: Procedure: pulp capping with MTA |
What is being measured
The primary outcome is the main question the study is designed to answer.
Spontaneous pain
numeric rating scale (presence or abscence of pain) 0 is best result 10 is the worst
Measured: 12 months
Radiolucency of the periapical or furcation area
measuring tool is x-ray
Measured: Follow up for 12 months
Secondary outcomes (5)
Presence or absence of fistula
Visual inspection
Measured: 12 months
Pathological mobility
Graded clinical by applying pressure by end of mirror
Measured: 12 months
Sensitivity on percussion
Methods of tapping on surface in clinical examination
Measured: 12 months
Widening of personal ligament space
Measuring tool is xray
Measured: 12 months
Internal or e ternal resorption
Measuring tool is xray
Measured: 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Jan 2026
- Study start1 Jun 2025
- Primary completion31 May 2026
- Study completion9 Jun 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Vital Pulp Therapy in Primary TeethStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 96 participants (actual)
Sponsor and investigators
- Lead sponsor
- Delta University for Science and Technology
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07333872
- Sponsor's protocol ID
- DU:025052113
- Status last verified
- May 2025
- First submitted
- 1 Jan 2026
- Last updated
- 19 Oct 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of Pulpotomy, Partial Pulpotomy, and Direct Pulp Capping Using Mineral Trioxide Aggregate in Primary Molars. A Randomized Clinical Trial.
- ClinicalTrials.gov ID
- NCT07333872
- Acronym / sponsor ID
- DU:025052113
- Conditions
- Vital Pulp Therapy in Primary Teeth
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 96 participants (actual)
- Lead sponsor
- Delta University for Science and TechnologyUniversity, hospital or other
- Study start
- 1 Jun 2025 (actual)
- Primary completion
- 31 May 2026 (actual)
- Study completion
- 9 Jun 2026 (actual)
- First posted
- 12 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
A comparative evaluation for three vital pulp therapy techniques in primary molars using the same material (MTA)
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Direct pulp capping | Experimental | Procedure: pulp capping with MTATechnique of vital pulp therapy to cap pin point exposure |
| Partial pulpotomy | Experimental | Procedure: pulp capping with MTATechnique of vital pulp therapy to cap widened pulp exposure |
| Pulpotomy | Experimental | Procedure: pulp capping with MTATechnique of vital pulp therapy of capping radicular pulp after removal of coronal pulp |
Who may qualify
- Ages
- 4 to 7 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (1 listed)
- articipants were cooperative children (4-7 years) with no systemic diseases or relevant allergies. Eligible teeth were restorable primary second molars with deep carious lesions and a diagnosis of reversible pulpitis,
Key exclusion criteria (1 listed)
- spontaneous pain, edema, fistula, pathological mobility, or percussion sensitivity.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| pulp capping with MTACapping of the pulp tissue with a biocompatible material (MTA) | Procedure or surgery | Direct pulp capping, Partial pulpotomy, Pulpotomy |
Primary outcome
Spontaneous pain
Time frame: 12 months
numeric rating scale (presence or abscence of pain) 0 is best result 10 is the worst
Radiolucency of the periapical or furcation area
Time frame: Follow up for 12 months
measuring tool is x-ray
5 secondary outcomes
Presence or absence of fistula
Time frame: 12 months
Pathological mobility
Time frame: 12 months
Sensitivity on percussion
Time frame: 12 months
Widening of personal ligament space
Time frame: 12 months
Internal or e ternal resorption
Time frame: 12 months
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Oct 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing pulp capping with MTA in people with Vital Pulp Therapy in Primary Teeth, run by Delta University for Science and Technology at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 19 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Spontaneous pain (time frame: 12 months). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Oct 2026.