Post-intensive Care SyndromeNCT07371741
PICS Clinic Attendance and Recovery Engagement (PICS-CARE)
An observational study of Post-intensive Care Syndrome, run by Charite University, Berlin, Germany at 1 site in Germany.
Trial summary
To identify relevant factors influencing attendance at appointments at the PICS outpatient clinic after intensive care treatment in order to derive targeted measures to increase the participation rate or send more targeted invitations. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Post-intensive Care Syndrome
- How many people
- 2,500 participants
- Where
- 1 siteGermany
- Study dates
- 10 Feb 2026to Feb 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Intensive Care unit patients, who were invited for follow-up care by the PICS outpatient clinic of the Department of Anesthesiology and Intensive Care Medicine (CCM/CVK)
Who may be able to join
- Patients who, between January 1, 2021, and December 31, 2025:
- were invited for follow-up care by the PICS outpatient clinic of the Department of Anesthesiology and Intensive Care Medicine (CCM/CVK)
- were ≥18 years old at the time of the appointment.
Who cannot join
- none
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Germany1 site, 1 recruiting
- Recruiting
Department of Anesthesiology and Intensive Care Medicine (CCM/CVK), Charité - Universitätsmedizin Berlin
Berlin, 13353
Claudia Spies, MD. Prof., +49 30 450 55 11 02, claudia.spies@charite.de
Claudia Spies, MD, Prof.
About this study
To identify relevant factors influencing attendance at appointments at the PICS outpatient clinic after intensive care treatment in order to derive targeted measures to increase the participation rate or send more targeted invitations.
Read the detailed description
This retrospective study examines which factors influence patient attendance at structured follow-up appointments after intensive care treatment in the PICS outpatient clinic at Charité. The focus is on analyzing demographic, clinical, and care-related factors that influence actual participation in follow-up care after intensive care treatment.
- Conditions
- Post-intensive Care Syndrome
- Medical subject headings
- postintensive care syndrome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Intensive care unit patients | Intensive care unit patients, which are invited in the post-intensive care outpatient clinic |
What is being measured
The primary outcome is the main question the study is designed to answer.
Follow-up appointment
Participation in the first scheduled follow-up appointment at the post-intensive care syndrome (PICS) outpatient clinic (binary: attended vs. did not attend) is measured by medical record review.
Measured: 01.01.2021- 31.12.2025
Secondary outcomes (9)
Cancellation of a scheduled follow-up appointment.
Cancellation of a scheduled follow-up appointment is measured by medical record review.
Measured: 01.01.2021- 31.12.2025
Reasons for canceling a scheduled appointment.
Reasons for canceling a scheduled appointment is measured by medical record review.
Measured: 01.01.2021- 31.12.2025
Failure to attend a scheduled follow-up appointment.
Failure to attend a scheduled follow-up appointment is measured by medical record review.
Measured: 01.01.2021- 31.12.2025
Death after discharge from the intensive care unit until the first follow-up appointment.
Death after discharge from the intensive care unit until the first follow-up appointment is measured by medical record review.
Measured: 01.01.2021- 31.12.2025
Death between the first and second follow-up appointments.
Death between the first and second follow-up appointments is measured by medical record review.
Measured: 01.01.2021- 31.12.2025
Scheduling a second follow-up appointment after initial presentation at the outpatient clinic.
Scheduling a second follow-up appointment after initial presentation at the outpatient clinic is measured by medical record review.
Measured: 01.01.2021- 31.12.2025
Attendance at the second scheduled follow-up appointment after initial presentation at the outpatient clinic.
Attendance at the second scheduled follow-up appointment after initial presentation at the outpatient clinic is measured by medical record review.
Measured: 01.01.2021- 31.12.2025
Scheduling a third follow-up appointment after initial presentation at the outpatient clinic.
Scheduling a third follow-up appointment after initial presentation at the outpatient clinic is is measured by medical record review.
Measured: 01.01.2021- 31.12.2025
Attendance at the third scheduled follow-up appointment after initial presentation at the outpatient clinic.
Attendance at the third scheduled follow-up appointment after initial presentation at the outpatient clinic is measured by medical record review.
Measured: 01.01.2021- 31.12.2025
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Jan 2026
- Study start10 Feb 2026
- Primary completionFeb 2027 (estimated)
- Study completionFeb 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Post-intensive Care SyndromeStudies of the same condition, open and under way.
- More trials run by Charite University, Berlin, GermanyThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 2,500 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Charite University, Berlin, Germany
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Claudia Spies, Charite University, Berlin, Germany
- Investigators
- Claudia Spies, MD, Prof., Study director, Charite University, Berlin, Germany
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07371741
- Sponsor's protocol ID
- PICS-CARE
- Status last verified
- Feb 2026
- First submitted
- 19 Jan 2026
- Last updated
- 12 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 12 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- PICS Clinic Attendance and Recovery Engagement (PICS-CARE)
- ClinicalTrials.gov ID
- NCT07371741
- Acronym / sponsor ID
- PICS-CARE
- Conditions
- Post-intensive Care Syndrome
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 2,500 participants (estimated)
- Lead sponsor
- Charite University, Berlin, GermanyUniversity, hospital or other
- Study start
- 10 Feb 2026 (actual)
- Primary completion
- Feb 2027 (estimated)
- Study completion
- Feb 2027 (estimated)
- First posted
- 28 Jan 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To identify relevant factors influencing attendance at appointments at the PICS outpatient clinic after intensive care treatment in order to derive targeted measures to increase the participation rate or send more targeted invitations.
Detailed description
This retrospective study examines which factors influence patient attendance at structured follow-up appointments after intensive care treatment in the PICS outpatient clinic at Charité. The focus is on analyzing demographic, clinical, and care-related factors that influence actual participation in follow-up care after intensive care treatment.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Intensive care unit patients | – | –Intensive care unit patients, which are invited in the post-intensive care outpatient clinic |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Intensive Care unit patients, who were invited for follow-up care by the PICS outpatient clinic of the Department of Anesthesiology and Intensive Care Medicine (CCM/CVK)
Key inclusion criteria (3 listed)
- Patients who, between January 1, 2021, and December 31, 2025:
- were invited for follow-up care by the PICS outpatient clinic of the Department of Anesthesiology and Intensive Care Medicine (CCM/CVK)
- were ≥18 years old at the time of the appointment.
Key exclusion criteria (1 listed)
- none
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Follow-up appointment
Time frame: 01.01.2021- 31.12.2025
Participation in the first scheduled follow-up appointment at the post-intensive care syndrome (PICS) outpatient clinic (binary: attended vs. did not attend) is measured by medical record review.
9 secondary outcomes
Cancellation of a scheduled follow-up appointment.
Time frame: 01.01.2021- 31.12.2025
Reasons for canceling a scheduled appointment.
Time frame: 01.01.2021- 31.12.2025
Failure to attend a scheduled follow-up appointment.
Time frame: 01.01.2021- 31.12.2025
Death after discharge from the intensive care unit until the first follow-up appointment.
Time frame: 01.01.2021- 31.12.2025
Death between the first and second follow-up appointments.
Time frame: 01.01.2021- 31.12.2025
Scheduling a second follow-up appointment after initial presentation at the outpatient clinic.
Time frame: 01.01.2021- 31.12.2025
Attendance at the second scheduled follow-up appointment after initial presentation at the outpatient clinic.
Time frame: 01.01.2021- 31.12.2025
Scheduling a third follow-up appointment after initial presentation at the outpatient clinic.
Time frame: 01.01.2021- 31.12.2025
Attendance at the third scheduled follow-up appointment after initial presentation at the outpatient clinic.
Time frame: 01.01.2021- 31.12.2025
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Feb 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Claudia Spies, MD, Prof. study director
Charite University, Berlin, Germany
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Post-intensive Care Syndrome, run by Charite University, Berlin, Germany at 1 site in Germany.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 12 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Germany. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Claudia Spies, MD, Prof. (+49 30 450 551102, claudia.spies@charite.de), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Follow-up appointment (time frame: 01.01.2021- 31.12.2025). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Feb 2026.