MeshNCT07386067
Mesh Design for Open Inguinal Hernia
A study testing new mesh design for inguinal hernia in people with Mesh and Inguinal Hernia, run by Zagazig University at 1 site in Egypt.
Trial summary
Inguinal hernia repair is the most common operation performed by general surgeons worldwide, surgical repair is the only established definitive treatment for inguinal hernia with multiple variable described approaches, Since Lichtenstein and his colleagues pronounced the use of mesh in tension-free inguinal hernia… Read more about this study
- Who is it for?
- Ages 18 years and older, men only
- Conditions the study is for
- Mesh, Inguinal Hernia
- What is being tested?
- new mesh design for inguinal hernia
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 100 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Jan 2025to 1 Jan 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- Men only
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- • males older than 18 years old with primary inguinal hernia.
Who cannot join
- females patients with bleeding tendency.
- Complicated inguinal hernia.
- Huge inguinoscrotal hernia
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Mesh Design for Open Inguinal Hernia Repair: Superior Outcomes and Fewer Complications
Inguinal hernia repair is the most common operation performed by general surgeons worldwide, surgical repair is the only established definitive treatment for inguinal hernia with multiple variable described approaches, Since Lichtenstein and his colleagues pronounced the use of mesh in tension-free inguinal hernia repair, the open Lichtenstein mesh repair of inguinal hernia became a standard of care for inguinal hernia repair due to easiness of performance with low recurrence rates (1, 2, 3).
In the past many different factors have been identified to reduce chronic postoperative inguinal pain CPIP, Sophisticated studies suggested that mechanical mesh fixation should be avoided, and proper knowledge of inguinal nerves is essential (4-9).
Read more
Surgeons must consider patient characteristics and mesh properties when selecting a mesh for hernia treatment. Mechanical compatibility between meshes and abdominal wall layers is crucial for avoiding complications. Lightweight, monofilament meshes with large pores and minimal surface area are ideal; however, the surgeon should never forget that the way the mesh is positioned as important as the type of mesh used. Despite the new materials available, surgical skill still has a major role in preventing hernia post-operative complications and recurrence. Future research will continue to focus on the surgical techniques and biomaterials to achieve the best outcomes (10).
Our method uses a smaller single mesh that covers all weaknesses in the inguinal canal and is covered with a fibro-cremasteric sheath to prevent the prosthesis from coming into touch with neural processes. This method is applicable to all cases of primary inguinal hernia.
- Conditions
- Mesh, Inguinal Hernia
- Being tested
- new mesh design for inguinal hernia
- Medical subject headings
- Hernia, Inguinal
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
new mesh design for inguinal herniaProcedure or surgery
the new mesh design is cut to fit the posterior wall of the inguinal canal
| Study group | Role | What they receive |
|---|---|---|
| hernia arm represent patients with inguinal hernia | Experimental | the new mesh desined to fit the posterior wall of inguinal canal Receives: Procedure: new mesh design for inguinal hernia |
What is being measured
The primary outcome is the main question the study is designed to answer.
hernia recurrence
The rate of return of the hernia in the same location.
Measured: 6 months following the operation
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted4 Feb 2026
- Study start1 Jan 2025
- Primary completion1 Jan 2026
- Study completion1 Jan 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for MeshStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 100 participants (actual)
Sponsor and investigators
- Lead sponsor
- Zagazig University
- Sponsor type
- Other government
- Responsible party
- Principal investigator, Yasser Ali Orban, Zagazig University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07386067
- Sponsor's protocol ID
- Mesh Design
- Status last verified
- Jan 2026
- First submitted
- 27 Jan 2026
- Last updated
- 4 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Mesh Design for Open Inguinal Hernia Repair: Superior Outcomes and Fewer Complications
- ClinicalTrials.gov ID
- NCT07386067
- Acronym / sponsor ID
- Mesh Design
- Conditions
- Mesh, Inguinal Hernia
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 100 participants (actual)
- Lead sponsor
- Zagazig UniversityOther government
- Study start
- 1 Jan 2025 (actual)
- Primary completion
- 1 Jan 2026 (actual)
- Study completion
- 1 Jan 2026 (actual)
- First posted
- 4 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Inguinal hernia repair is the most common operation performed by general surgeons worldwide, surgical repair is the only established definitive treatment for inguinal hernia with multiple variable described approaches, Since Lichtenstein and his colleagues pronounced the use of mesh in tension-free inguinal hernia repair, the open Lichtenstein mesh repair of inguinal hernia became a standard of care for inguinal hernia repair due to easiness of performance with low recurrence rates (1, 2, 3).
In the past many different factors have been identified to reduce chronic postoperative inguinal pain CPIP, Sophisticated studies suggested that mechanical mesh fixation should be avoided, and proper knowledge of inguinal nerves is essential (4-9).
Surgeons must consider patient characteristics and mesh properties when selecting a mesh for hernia treatment. Mechanical compatibility between meshes and abdominal wall layers is crucial for avoiding complications. Lightweight, monofilament meshes with large pores and minimal surface area are ideal; however, the surgeon should never forget that the way the mesh is positioned as important as the type of mesh used. Despite the new materials available, surgical skill still has a major role in preventing hernia post-operative complications and recurrence. Future research will continue to focus on the surgical techniques and biomaterials to achieve the best outcomes (10).
Our method uses a smaller single mesh that covers all weaknesses in the inguinal canal and is covered with a fibro-cremasteric sheath to prevent the prosthesis from coming into touch with neural processes. This method is applicable to all cases of primary inguinal hernia.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| hernia arm represent patients with inguinal hernia | Experimental | Procedure: new mesh design for inguinal herniathe new mesh desined to fit the posterior wall of inguinal canal |
Who may qualify
- Ages
- 18 years and older
- Sex
- Male only
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- • males older than 18 years old with primary inguinal hernia.
Key exclusion criteria (3 listed)
- females patients with bleeding tendency.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| new mesh design for inguinal herniathe new mesh design is cut to fit the posterior wall of the inguinal canal | Procedure or surgery | hernia arm represent patients with inguinal hernia |
Primary outcome
hernia recurrence
Time frame: 6 months following the operation
The rate of return of the hernia in the same location.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Feb 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing new mesh design for inguinal hernia in people with Mesh and Inguinal Hernia, run by Zagazig University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 4 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
hernia recurrence (time frame: 6 months following the operation). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Feb 2026.