Clinical trials: Mesh
Ileostomy - Stoma, Inflammatory Bowel Diseases
Stoma Closure and Reinforcement Trial ll
Hernia formation at sites of ostomy closure is a common complication. The investigator believes that using evidence based hernia repair techniques as a preventive measure during closure of ostomies will reduce the incidence of…
- Trial name
- SCAR-ll (NCT04916067)
- Testing
- Mesh Implantation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Umbilical Hernia
Visible vs. Non-Visible Mesh in Underlay Positon After Repair of Umbilical Hernias
The purpose of this study is to determine the exact position of a mesh which is placed in underlay position in umbilical hernia in vitro.
- Trial name
- NANEP (NCT03200405)
- Testing
- DynaMeshVisible, DynaMeshCICAT
- Where
- Germany
- Volunteers
- 31 people
- Sponsor
- Wuerzburg University Hospital
Postoperative Pain, Chronic Pain
Chronic Postoperative Pain After Laparoendoscopic Groin Hernia Repair
The study attempts to quantify the relative risks for chronic postoperative inguinal pain (CPIP) depending on different combinations of mesh and mesh fixation.
- Trial name
- NCT04838028
- Testing
- TEP, TAPP, Other or unspecified laparoendoscopic groin hernia repair
- Volunteers
- 15,360 people
- Sponsor
- Karolinska Institutet
Non-Alcoholic Fatty Liver Disease, Probiotics MeSH Descriptor Data 2018
Effects of Probiotic on Inflammation and Microbiota in Patients With NASH
Individuals with clinically identified non-alcoholic fatty liver disease will undergo baseline evaluation of IL-17 and other inflammatory markers as well as microbiome determination.
- Conditions
- Non-Alcoholic Fatty Liver Disease, Probiotics MeSH Descriptor Data 2018, Interleukin-17 MeSH Descriptor Data 2018
- Trial name
- NASHPro (NCT03511365)
- Testing
- Probiotic Formulation VSL#3
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Northwell Health
Stress Urinary Incontinence
Mesh-free Suture Urethropexy for Treating Stress Urinary Incontinence, Efficacy and Durability Trial
In this proposed study, the investigators aim to evaluate a modified suture urethropexy technique for the treatment of female stress urinary incontinence.
- Trial name
- NCT04881721
- Testing
- Urethropexy
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Aphakia, Postcataract
Yamani Technique Versus Proline Mesh for Intraocular Lens Scleral Fixation in Aphakia
The study aims to describe a new method of sulcus fixation of intraocular lenses (IOLs) using a prolene mesh and to compare its outcomes with Yamani technique.
- Trial name
- NCT06363448
- Testing
- Yamani Technique versus Prolene Mesh for Intraocular Lens Scleral Fixation in Aphakia
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Sohag University
Mastectomy; Lymphedema, Breast Cancer
Examining and Comparing the Temporal Changes and Results of Cosmetic, Quality of Life and Patient Satisfaction Achieved With Immediate and Delayed-immediate Implant-based Breast Reconstruction Procedures and Contralateral Symmetrization Techniques
This is a response-adaptive (RAR) prospective randomized study with a long-term follow-up and the aim of this clinical study is to measure with qualitative and quantitative indicators the changes in cosmetic results, quality of…
- Conditions
- Mastectomy; Lymphedema, Breast Cancer, Quality of Life
- Trial name
- NCT04356235
- Testing
- A: expander-silicone implant exchange and contralateral symmetrization with mastopexy and if needed with volume reduction, B: expander-silicone implant exchange with contralateral symmetrization with mastopexy and Ultrapro sling, C: expander-silicone implant exchange and contralateral symmetrization with mastopexy and silicone implant augmentation
- Where
- Hungary
- Volunteers
- 528 people, healthy volunteers welcome
- Sponsor
- National Institute of Oncology, Hungary
Incidence of Mesh Infection In Hernioplasty
Incidence Of Mesh Infection After Hernioplasty In Obstructed and Strangulated Hernia Using Proline Mesh and Sutures
The primary aim of this study is to detect incidence of mesh infection in cases presented with obstructed or strandulated hernia.A prospective controlled study will be carried out after obtaining written informed consent from all…
- Trial name
- NCT05775276
- Testing
- Proline mesh in hernioplasty
- Volunteers
- 60 people
- Sponsor
- Assiut University
Coronary Artery Disease, Myocardial Ischemia
The eSVS® Mesh Randomized Post-Market Study
The purpose of this study is to evaluate patency rates of the external Saphenous Vein Support (eSVS) Mesh Saphenous Vein Grafts (SVG) and Control SVG at 3-6 months and 24 months.
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Coronary Disease, Heart Diseases
- Trial name
- NCT01462721
- Testing
- eSVS® Mesh
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Kips Bay Medical, Inc.
Postoperative Complications
TAPP Inguinal Hernia Repair With Self-fixating Parietex™ ProGrip™ Mesh
The objective of this retrospective study is to evaluate the postoperative clinical outcomes at discharge, 1 month and 12 months, associated with the use of Parietex™ ProGrip™ in Laparoscopic Transabdominal preperitoneal inguinal…
- Trial name
- NCT01481376
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Medtronic - MITG
Surgical Wound Dehiscence, Cutis Laxa
Use of 2-octyl-cyanoacrylate Together With a Self-adhering Mesh
The investigators prospectively studied the results of wound closure after abdominoplasty with randomized use of PrineoTM and conventional suturing to assess the possible difference in outcome between these two methods.Follow-up…
- Conditions
- Surgical Wound Dehiscence, Cutis Laxa, Wound of Skin
- Trial name
- NCT01658163
- Volunteers
- 2 people
- Sponsor
- Medical University of Graz
Wound With Foreign Body (With or Without Infection)
Frequency of Surgical Site Infection in Abdominal Hernia With Gentamycin Spray on Mesh Versus no Spray
Patient diagnosed with Para umbilical hernia, umbilical hernia, epigastric will be selected for the study. Sampling technique will be systematic with every 2nd patient being exposed to Gentamycin spray during mesh repair. .
- Trial name
- NCT04164524
- Testing
- Gentamycin
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Dow University of Health Sciences
Ventral Hernia
Bariatric SUrgery With Mesh REpair of Ventral Hernia: a Randomized Controlled Trial
The primary objective of the study is to demonstrate that hernia recurrence (VH) repair with non absorbable mesh concomitant to Bariatric Surgery (BS) decreases the risk of VH, with or without surgical repair, during the first…
- Trial name
- BeSURE (NCT05488288)
- Testing
- Mesh repair, Suture repair
- Where
- France
- Volunteers
- 354 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Rectovaginal Fistula, Crohn Disease
Treatment of Rectovaginal Crohn's Fistula by Combination of TAAM Injection and Biological Plug Placement
Interventional, prospective, randomized, controlled, double blind, parallel groups, nonprofit, single center trial
- Trial name
- LIPOPLUG (NCT06813768)
- Testing
- Microfractured adipose tissue injection and plug placement
- Where
- Italy
- Volunteers
- 3 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Incisional Hernia After Midline Laparotomy, Quality of Life (QOL)
NoPro - Norwegian Hernia Prophylaxis Study
A multicenter randomized controlled trial comparing midline laparotomy closures using the small-bite suture technique alone to those using the small-bite suture technique with an additional onlay prophylactic polypropylene mesh.
- Conditions
- Incisional Hernia After Midline Laparotomy, Quality of Life (QOL), Burst Abdomen, Surgical Site Infections
- Trial name
- NoPro (NCT06858020)
- Testing
- Prophylactic polypropylene onlay mesh
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Sykehuset Innlandet HF
Bilateral Inguinal Hernia
Laparoscopic Versus Open Mesh Repair of Bilateral Primary Inguinal Hernia
The best approach for simultaneous repair of bilateral inguinal hernia is controversial. The aim of this study is to compare the outcomes after laparoscopic versus open mesh repair of bilateral primary inguinal hernia
- Trial name
- NCT04437784
- Testing
- Laparoscopic Trans-Abdominal Pre-Peritoneal, Open pre-peritoneal repair, Bilateral Lichtenstein repair
- Volunteers
- 180 people
- Sponsor
- Alexandria University
Ventral Hernia
Prospective Clinical Observational Cohort Study to Evaluate the Use of a Tissue Separating Mesh (Proceed®) in Laparoscopic Ventral Hernia Repair
1. General: antibiotic prophylaxis: cefazoline (Cefacidal™) 2 gram iv administered 30 minutes before surgery 2. Laparoscopic surgery at least 5 cm overlap (mesh diameter should exceed hernia size by at least 10 cm) with or…
- Trial name
- NCT00572962
- Testing
- use of a tissue separating mesh (Proceed®) in Laparoscopic Ventral hernia repair
- Where
- Belgium
- Volunteers
- 210 people
- Sponsor
- University Hospital, Ghent
Cancer, Therapy-Related
Proton Therapy Medical Registry
Clínica Universidad de Navarra Proton Therapy Unit is establishing a registry to capture the full radiation dosimetry delivered to the patient, baseline clinical data, and disease, toxicity and quality of life outcomes.
- Trial name
- NCT05151952
- Testing
- Other: Registry
- Where
- 2 sites in Spain
- Volunteers
- 6,000 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Pelvic Organ Prolapse
Pelvic Floor Repair Systems for Prolapse Repair
1. This is a prospective, multi-center, post market study, which will be conducted under a common protocol. 2. The primary objective of the study is to evaluate long-term efficacy of the AMS Pelvic Floor Repair System devices for…
- Trial name
- PROPEL (NCT00638235)
- Testing
- AMS Apogee™ with IntePro, AMS Apogee™ with Intexen LP, AMS Perigee™ with IntePro
- Where
- 28 sites in United States, Belgium and 5 more
- Volunteers
- 725 people
- Sponsor
- ASTORA Women's Health
Breast Cancer
Breast Reconstruction With Acellular Dermal Matrix in the Setting of Breast Cancer Treatment
To evaluate breast reconstruction with implants using biological mesh (Strattice™) in the setting of breast cancer treatment.
- Trial name
- NCT02061527
- Testing
- Reconstruction with ADM., Skin or nipple sparing mastectomy, Reconstruction with implant
- Where
- 5 sites in Sweden, United Kingdom
- Volunteers
- 135 people
- Sponsor
- Karolinska University Hospital