Thumb InjuryNCT07388316
Functional Improvement and Fine Dexterity in Thumb Tendon Injuries
An observational study of Thumb Injury and Tendon Injuries, run by Pamukkale University at 1 site in Turkey (Türkiye).
Trial summary
Considering the thumb's contribution to fine dexterity and precision grip, this study aims to evaluate fine manual dexterity alongside functional outcomes following isolated thumb tendon injuries, and to examine the relationship between postoperative functional improvement and changes in fine manual dexterity. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Thumb Injury, Tendon Injuries
- What is being tested?
- Questionnaire and Physical Exam
- How many people
- 52 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 26 Feb 2026to 1 Mar 2027
- How long will I take part?
- 24 Weeks
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients with surgically repaired isolated thumb tendon injuries
Who may be able to join
- No history of neurological, orthopaedic, rheumatological, metabolic disease or surgery in the relevant extremity
Who cannot join
- Comorbid musculoskeletal-neurovascular injuries
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Pamukkale University
Denizli, 20170
Umut Eraslan, +905444126520, ueraslan@pau.edu.tr
About this study
Official title: Investigation of the Relationship Between Functional Improvement and Changes in Fine Manual Dexterity in Isolated Thumb Tendon Injuries
Considering the thumb's contribution to fine dexterity and precision grip, this study aims to evaluate fine manual dexterity alongside functional outcomes following isolated thumb tendon injuries, and to examine the relationship between postoperative functional improvement and changes in fine manual dexterity.
- Conditions
- Thumb Injury, Tendon Injuries
- Being tested
- Questionnaire and Physical Exam
- Keywords
- functional status, fine dexterity, thumb, tendon injury
- Medical subject headings
- Tendon Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Questionnaire and Physical ExamOther
Joint range of motion, fine manual dexterity, reaction time, and grip strength will be assessed, and the Michigan Hand Outcomes Questionnaire will be administered to the patients.
| Study group | Role | What they receive |
|---|---|---|
| Patients diagnosed with isolated thumb tendon injuries at the hand level, who underwent surgical tre | Not described Receives: Other: Questionnaire and Physical Exam |
What is being measured
The primary outcome is the main question the study is designed to answer.
Goniometric measurement
Joint mobility will be measured in degrees (°) using a universal goniometer. Active flexion and extension of the Metacarpophalangeal (MCP) and Interphalangeal (IP) joints will be recorded. Higher degrees indicate better joint mobility.
Measured: At postoperative 12th and 24th week
Gross and fine grip strength
Gross grip strength will be measured in kilograms (kg) using a Jamar Hand Dynamometer. Fine grip strength will be measured in kilograms (kg) using a Jamar Pinch gauge. Key pinch, tip-to-tip pinch, tripod pinch and pulp-to-pulp pinch strengths will be assessed. Patients will perform three maximum effort trials, and the mean value will be recorded. Higher values indicate greater strength.
Measured: At postoperative 12th and 24th week
Michigan Hand Outcomes Questionnaire
he questionnaire covers 6 domains: overall hand function, activities of daily living, pain, work performance, appearance, and satisfaction. Total scores range from 0 to 100. For the pain domain, higher scores indicate more pain; for all other domains, higher scores indicate better hand function.
Measured: At postoperative 12th and 24th week
The O'Connor Finger Dexterity Test
The unit of measure is the time in seconds required to complete the placement of pins in the board. Lower time values indicate better fine motor skill and manual dexterity.
Measured: At postoperative 12th and 24th week
The Nelson Hand Reaction Test
The participant's reaction is measured by the distance the ruler falls before being caught measured in centimeters.Lower values (shorter distance) indicate faster reaction speed and better neuromuscular coordination.
Measured: At postoperative 12th and 24th week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Feb 2026
- Study start26 Feb 2026 (estimated)
- Primary completion1 Mar 2027 (estimated)
- Study completion1 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Thumb InjuryStudies of the same condition, open and under way.
- More trials run by Pamukkale UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 52 participants (estimated)
- Target duration
- 24 Weeks
Sponsor and investigators
- Lead sponsor
- Pamukkale University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, UMUT ERASLAN, Pamukkale University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07388316
- Sponsor's protocol ID
- E-60116787-020-808746
- Status last verified
- Feb 2026
- First submitted
- 28 Jan 2026
- Last updated
- 6 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Starr HM, Snoddy M, Hammond KE, Seiler JG 3rd. Flexor tendon repair rehabilitation protocols: a systematic review. J Hand Surg Am. 2013 Sep;38(9):1712-7.e1-14. doi: 10.1016/j.jhsa.2013.06.025.
PubMed 23981421Caron Y. The real role of thumb in the overall function of hand. Sci Insights. 2025;47(3):1963-6.
Study at a glance
From the registry record, last updated by the sponsor on 6 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Relationship Between Functional Improvement and Changes in Fine Manual Dexterity in Isolated Thumb Tendon Injuries
- ClinicalTrials.gov ID
- NCT07388316
- Acronym / sponsor ID
- E-60116787-020-808746
- Conditions
- Thumb Injury, Tendon Injuries
- Keywords
- functional status, fine dexterity, thumb, tendon injury
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 52 participants (estimated)
- Lead sponsor
- Pamukkale UniversityUniversity, hospital or other
- Study start
- 26 Feb 2026 (estimated)
- Primary completion
- 1 Mar 2027 (estimated)
- Study completion
- 1 Mar 2027 (estimated)
- First posted
- 5 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Considering the thumb's contribution to fine dexterity and precision grip, this study aims to evaluate fine manual dexterity alongside functional outcomes following isolated thumb tendon injuries, and to examine the relationship between postoperative functional improvement and changes in fine manual dexterity.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 24 Weeks
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Patients diagnosed with isolated thumb tendon injuries at the hand level, who underwent surgical tre | – | Other: Questionnaire and Physical Exam |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- Patients with surgically repaired isolated thumb tendon injuries
Key inclusion criteria (1 listed)
- No history of neurological, orthopaedic, rheumatological, metabolic disease or surgery in the relevant extremity
Key exclusion criteria (1 listed)
- Comorbid musculoskeletal-neurovascular injuries
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Questionnaire and Physical ExamJoint range of motion, fine manual dexterity, reaction time, and grip strength will be assessed, and the Michigan Hand Outcomes Questionnaire will be administered to the patients. | Other | Patients diagnosed with isolated thumb tendon injuries at the hand level, who underwent surgical tre |
Primary outcome
Goniometric measurement
Time frame: At postoperative 12th and 24th week
Joint mobility will be measured in degrees (°) using a universal goniometer. Active flexion and extension of the Metacarpophalangeal (MCP) and Interphalangeal (IP) joints will be recorded. Higher degrees indicate better joint mobility.
Gross and fine grip strength
Time frame: At postoperative 12th and 24th week
Gross grip strength will be measured in kilograms (kg) using a Jamar Hand Dynamometer. Fine grip strength will be measured in kilograms (kg) using a Jamar Pinch gauge. Key pinch, tip-to-tip pinch, tripod pinch and pulp-to-pulp pinch strengths will be assessed. Patients will perform three maximum effort trials, and the mean value will be recorded. Higher values indicate greater strength.
Michigan Hand Outcomes Questionnaire
Time frame: At postoperative 12th and 24th week
he questionnaire covers 6 domains: overall hand function, activities of daily living, pain, work performance, appearance, and satisfaction. Total scores range from 0 to 100. For the pain domain, higher scores indicate more pain; for all other domains, higher scores indicate better hand function.
The O'Connor Finger Dexterity Test
Time frame: At postoperative 12th and 24th week
The unit of measure is the time in seconds required to complete the placement of pins in the board. Lower time values indicate better fine motor skill and manual dexterity.
The Nelson Hand Reaction Test
Time frame: At postoperative 12th and 24th week
The participant's reaction is measured by the distance the ruler falls before being caught measured in centimeters.Lower values (shorter distance) indicate faster reaction speed and better neuromuscular coordination.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Feb 2026.
- Background: PubMed 23981421Starr HM, Snoddy M, Hammond KE, Seiler JG 3rd. Flexor tendon repair rehabilitation protocols: a systematic review. J Hand Surg Am. 2013 Sep;38(9):1712-7.e1-14. doi: 10.1016/j.jhsa.2013.06.025.
- BackgroundCaron Y. The real role of thumb in the overall function of hand. Sci Insights. 2025;47(3):1963-6.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Thumb Injury and Tendon Injuries, run by Pamukkale University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 6 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Umut Eraslan (+905444126520, ueraslan@pau.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Goniometric measurement (time frame: At postoperative 12th and 24th week). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07388316, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Feb 2026.