Adolescent Idiopathic Scoliosis (AIS)TPSA-SNCT07408843
Correlation Between Trunk Postural Changes by Mobile Application and Radiological Findings in Adolescent Idiopathic Scoliotic Females
An observational study of Adolescent Idiopathic Scoliosis (AIS), run by Beni-Suef University at 1 site in Egypt.
Trial summary
This observational study aims to examine the relationship between trunk postural changes measured using a mobile application (Biotonix Posture Assistant) and spinal curvature assessed by radiographic Cobb angle in adolescent females with idiopathic scoliosis. Read more about this study
- Who is it for?
- Ages 14 to 17 years, women only
- Conditions the study is for
- Adolescent Idiopathic Scoliosis (AIS)
- How many people
- 30 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Sep 2024to 30 Aug 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 14 to 17 years
- Women only
- No healthy volunteers
- Child
Study population: Female adolescents aged 14-17 years Diagnosed with adolescent idiopathic scoliosis
Who may be able to join
- Female adolescents aged 14-17 years
- Diagnosed with adolescent idiopathic scoliosis
- Cobb angle between 40° and 60°
- Ability to stand independently for posture assessment
Who cannot join
- Congenital scoliosis
- Neuromuscular scoliosis
- Previous spinal surgery
- Leg length discrepancy greater than 2 cm
- Any musculoskeletal disorder affecting posture
- Any neurological disorder affecting posture
- Thyroid disease
Trial locations and contacts
1 site in 1 country.
About this study
This observational study aims to examine the relationship between trunk postural changes measured using a mobile application (Biotonix Posture Assistant) and spinal curvature assessed by radiographic Cobb angle in adolescent females with idiopathic scoliosis. Thirty girls aged 14 to 17 years with moderate scoliosis will undergo a single posture assessment using the mobile application and a standard spinal X-ray. The study seeks to determine whether mobile-based postural measurements can reliably reflect radiological findings, offering a non-invasive and radiation-free option for screening and monitoring spinal posture in adolescents with scoliosis.
Read the detailed description
Detailed Description
Adolescent idiopathic scoliosis is a common spinal deformity that typically develops during the adolescent growth period and predominantly affects females. Accurate assessment of spinal curvature is essential for clinical decision-making and follow-up; however, repeated radiographic evaluation exposes patients to ionizing radiation. Therefore, non-invasive assessment tools are increasingly needed.
This observational cross-sectional study aims to investigate the relationship between trunk postural deviations measured using the Biotonix Posture Assistant mobile application and radiographic Cobb angle measurements in adolescent females diagnosed with idiopathic scoliosis. Thirty female participants aged 14 to 17 years with moderate scoliosis (Cobb angle between 40° and 60°) will be recruited.
Each participant will undergo a single postural assessment using the mobile application to measure trunk rotation and translation along the X and Y axes while standing in a standardized position. Standard posteroanterior spinal radiographs will be used to determine Cobb angles as part of routine clinical evaluation. No therapeutic intervention will be applied as part of this study.
Statistical analysis will include correlation and regression methods to explore the association between postural parameters obtained from the mobile application and radiographic findings. The results of this study are expected to support the clinical utility of mobile-based posture assessment as a complementary, non-radiographic tool for screening and monitoring spinal deformities in adolescents
- Conditions
- Adolescent Idiopathic Scoliosis (AIS)
- Keywords
- spinal assessment., mobile application, Cobb angle, Biotonix, Adolescent idiopathic scoliosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Adolescent Idiopathic Scoliosis Group | This group includes female adolescents aged 14 to 17 years diagnosed with moderate adolescent idiopathic scoliosis (Cobb angle 40°-60°). Participants undergo a single assessment of trunk posture using a mobile application (Biotonix Posture Assistant) and standard posteroanterior spinal radiography as part of routine clinical evaluation. No therapeutic or experimental intervention is applied in this study |
What is being measured
The primary outcome is the main question the study is designed to answer.
Correlation between BPA-derived trunk postural parameters and radiographic Cobb angle
Measured: baseline assessment at study enrollment
Secondary outcomes (1)
Correlation between trunk rotation (X and Y axes) and Cobb angle Correlation between trunk translation (X and Y axes) and Cobb angle Predictive value of BPA parameters for Cobb angle estimation
Measured: baseline assessment at study enrollment
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Feb 2026
- Study start1 Sep 2024
- Primary completion30 Aug 2025
- Study completion30 Aug 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Adolescent Idiopathic Scoliosis (AIS)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Beni-Suef University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Abd El-Hamied Ibrahim El-Sayed Mohammad El-Sherbini, Beni-Suef University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07408843
- Sponsor's protocol ID
- IRB0001P4233-41.
- Other IDs
- IRB0001P4233-41.
- Acronym
- TPSA-S
- Status last verified
- Feb 2026
- First submitted
- 30 Jan 2026
- Last updated
- 13 Feb 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 13 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Correlation Between Trunk Postural Changes by Mobile Application and Radiological Findings in Adolescent Idiopathic Scoliotic Females
- ClinicalTrials.gov ID
- NCT07408843
- Acronym / sponsor ID
- TPSA-S / IRB0001P4233-41.
- Conditions
- Adolescent Idiopathic Scoliosis (AIS)
- Keywords
- spinal assessment., mobile application, Cobb angle, Biotonix, Adolescent idiopathic scoliosis
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Beni-Suef UniversityUniversity, hospital or other
- Study start
- 1 Sep 2024 (actual)
- Primary completion
- 30 Aug 2025 (actual)
- Study completion
- 30 Aug 2025 (actual)
- First posted
- 13 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This observational study aims to examine the relationship between trunk postural changes measured using a mobile application (Biotonix Posture Assistant) and spinal curvature assessed by radiographic Cobb angle in adolescent females with idiopathic scoliosis. Thirty girls aged 14 to 17 years with moderate scoliosis will undergo a single posture assessment using the mobile application and a standard spinal X-ray. The study seeks to determine whether mobile-based postural measurements can reliably reflect radiological findings, offering a non-invasive and radiation-free option for screening and monitoring spinal posture in adolescents with scoliosis.
Detailed description
Detailed Description
Adolescent idiopathic scoliosis is a common spinal deformity that typically develops during the adolescent growth period and predominantly affects females. Accurate assessment of spinal curvature is essential for clinical decision-making and follow-up; however, repeated radiographic evaluation exposes patients to ionizing radiation. Therefore, non-invasive assessment tools are increasingly needed.
This observational cross-sectional study aims to investigate the relationship between trunk postural deviations measured using the Biotonix Posture Assistant mobile application and radiographic Cobb angle measurements in adolescent females diagnosed with idiopathic scoliosis. Thirty female participants aged 14 to 17 years with moderate scoliosis (Cobb angle between 40° and 60°) will be recruited.
Each participant will undergo a single postural assessment using the mobile application to measure trunk rotation and translation along the X and Y axes while standing in a standardized position. Standard posteroanterior spinal radiographs will be used to determine Cobb angles as part of routine clinical evaluation. No therapeutic intervention will be applied as part of this study.
Statistical analysis will include correlation and regression methods to explore the association between postural parameters obtained from the mobile application and radiographic findings. The results of this study are expected to support the clinical utility of mobile-based posture assessment as a complementary, non-radiographic tool for screening and monitoring spinal deformities in adolescents
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Adolescent Idiopathic Scoliosis Group | – | –This group includes female adolescents aged 14 to 17 years diagnosed with moderate adolescent idiopathic scoliosis (Cobb angle 40°-60°). Participants undergo a single assessment of trunk posture using a mobile application (Biotonix Posture Assistant) and standard posteroanterior spinal radiography as part of routine clinical evaluation. No therapeutic or experimental intervention is applied in this study |
Who may qualify
- Ages
- 14 to 17 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Child
- Study population
- Female adolescents aged 14-17 years Diagnosed with adolescent idiopathic scoliosis
Key inclusion criteria (4 listed)
- Female adolescents aged 14-17 years
- Diagnosed with adolescent idiopathic scoliosis
- Cobb angle between 40° and 60°
- Ability to stand independently for posture assessment
Key exclusion criteria (7 listed)
- Congenital scoliosis
- Neuromuscular scoliosis
- Previous spinal surgery
- Leg length discrepancy greater than 2 cm
- Any musculoskeletal disorder affecting posture
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Correlation between BPA-derived trunk postural parameters and radiographic Cobb angle
Time frame: baseline assessment at study enrollment
1 secondary outcome
Correlation between trunk rotation (X and Y axes) and Cobb angle Correlation between trunk translation (X and Y axes) and Cobb angle Predictive value of BPA parameters for Cobb angle estimation
Time frame: baseline assessment at study enrollment
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Feb 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Adolescent Idiopathic Scoliosis (AIS), run by Beni-Suef University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 13 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Correlation between BPA-derived trunk postural parameters and radiographic Cobb angle (time frame: baseline assessment at study enrollment). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Feb 2026.