HealthyNCT07419750
Relationship Between Muscle Strength and Balance
An observational study of Healthy and Chronic Ankle Instability, CAI, run by Biruni University at 1 site in Turkey (Türkiye).
Trial summary
This study aims to examine the relationship between lower extremity muscle strength and balance and to compare these parameters between healthy individuals and individuals with lower extremity injuries. Read more about this study
- Who is it for?
- Ages 18 to 40 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy, Chronic Ankle Instability, CAI, Anterior Cruciate Ligament Injury
- How many people
- 72 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 4 Aug 2025to 2 Mar 2026
- How long will I take part?
- 2 Days
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- Healthy volunteers accepted
- Adult
Study population: The study population will consist of adults aged 18-40 years, including individuals with a unilateral anterior cruciate ligament injury, individuals with chronic ankle instability, and healthy controls. Participants with lower extremity injuries will have a confirmed diagnosis within the past 6 to 18 months. All participants will be able to speak, read, and understand Turkish and will voluntarily consent to participate in the study.
Who may be able to join
- Anterior Cruciate Ligament (ACL) Injury Group:
- Aged between 18 and 40 years
- Diagnosed with a unilateral ACL injury 6 to 18 months prior to participation
- Diagnosis confirmed by magnetic resonance imaging (MRI)
- Ability to speak, read, and understand Turkish
- Willingness to participate voluntarily in the study
Show all 18Show fewer
- Chronic Ankle Instability (CAI) Group:
- Aged between 18 and 40 years
- Diagnosed with chronic ankle instability due to recurrent ankle sprains 6 to 18 months prior to participation
- History of at least two ankle sprains
- Ongoing symptoms of functional ankle instability (e.g., episodes of giving way, feelings of instability)
- Ability to speak, read, and understand Turkish
- Willingness to participate voluntarily in the study
- Healthy Control Group:
- Aged between 18 and 40 years
- No history of lower extremity injury or orthopedic diagnosis
- Ability to speak, read, and understand Turkish
- Willingness to participate voluntarily in the study
Who cannot join
- Presence of neurological, vestibular, or visual disorders that may affect balance
- History of other orthopedic diseases or trauma
- Presence of musculoskeletal disorders or cardiovascular comorbidities
- History of physiotherapy, rehabilitation, or surgical intervention within the past 6 months
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Relationship Between Muscle Strength and Balance: A Comparison Between Healthy Individuals and Those With Lower Extremity Injuries
This study aims to examine the relationship between lower extremity muscle strength and balance and to compare these parameters between healthy individuals and individuals with lower extremity injuries.
- Conditions
- Healthy, Chronic Ankle Instability, CAI, Anterior Cruciate Ligament Injury, Muscle Strengh, Balance
- Medical subject headings
- Anterior Cruciate Ligament Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Healthy Controls | Not described | |
| ACL Injury Group | Not described | |
| CAI Group | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
Dynamic Postural Control-ALFA Stabilometric Platform
Dynamic balance performance will be assessed using the ALFA Stabilometric Platform. The device software calculates an overall dynamic balance performance score based on center of pressure. Higher scores indicating better dynamic postural control performance.
Measured: Baseline
Secondary outcomes (5)
Static Balance Performance
Static balance performance will be assessed using a single-leg stance test under eyes-open and eyes-closed conditions. Participants will stand barefoot on one leg with hands on the hips, and the duration of maintaining balance will be recorded in seconds. Higher scores indicate better static balance performance.
Measured: Baseline
Isokinetic Muscle Strength
Isokinetic muscle strength will be assessed using an isokinetic dynamometer. Peak torque values of the knee extensor (quadriceps) and flexor (hamstrings), as well as ankle plantar flexor and dorsiflexor muscle groups, will be recorded.
Measured: Baseline
Isokinetic Muscle Endurance
Isokinetic muscle endurance will be assessed using an isokinetic dynamometer. Endurance-related parameters of the knee extensor (quadriceps) and flexor (hamstrings), as well as ankle plantar flexor and dorsiflexor muscle groups, will be recorded during repeated contractions.
Measured: Baseline
Pain Intensity
Pain intensity during activity will be assessed using the Visual Analog Scale (VAS). The scale ranges from 0 to 10, where 0 indicates no pain and 10 indicates the worst imaginable pain. Higher scores indicate greater pain intensity.
Measured: Baseline
Kinesiophobia
Fear of movement will be assessed using the Tampa Scale for Kinesiophobia. The total score ranges from 17 to 68, with higher scores indicating greater fear of movement.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Feb 2026
- Study start4 Aug 2025
- Primary completion2 Feb 2026
- Study completion2 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HealthyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 72 participants (actual)
- Target duration
- 2 Days
Sponsor and investigators
- Lead sponsor
- Biruni University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Begum Kara Kaya, Biruni University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07419750
- Sponsor's protocol ID
- 19.12
- Status last verified
- Jul 2025
- First submitted
- 19 Dec 2025
- Last updated
- 6 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Relationship Between Muscle Strength and Balance: A Comparison Between Healthy Individuals and Those With Lower Extremity Injuries
- ClinicalTrials.gov ID
- NCT07419750
- Acronym / sponsor ID
- 19.12
- Conditions
- Healthy, Chronic Ankle Instability, CAI, Anterior Cruciate Ligament Injury, Muscle Strengh, Balance
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 72 participants (actual)
- Lead sponsor
- Biruni UniversityUniversity, hospital or other
- Study start
- 4 Aug 2025 (actual)
- Primary completion
- 2 Feb 2026 (actual)
- Study completion
- 2 Mar 2026 (actual)
- First posted
- 19 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to examine the relationship between lower extremity muscle strength and balance and to compare these parameters between healthy individuals and individuals with lower extremity injuries.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Target follow-up
- 2 Days
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Healthy Controls | – | – |
| ACL Injury Group | – | – |
| CAI Group | – | – |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
- Study population
- The study population will consist of adults aged 18-40 years, including individuals with a unilateral anterior cruciate ligament injury, individuals with chronic ankle instability, and healthy controls. Participants with lower extremity injuries will have a confirmed diagnosis within the past 6 to 18 months. All participants will be able to speak, read, and understand Turkish and will voluntarily consent to participate in the study.
Key inclusion criteria (18 listed)
- Aged between 18 and 40 years
- Diagnosed with a unilateral ACL injury 6 to 18 months prior to participation
- Diagnosis confirmed by magnetic resonance imaging (MRI)
- Ability to speak, read, and understand Turkish
- Willingness to participate voluntarily in the study
Key exclusion criteria (4 listed)
- Presence of neurological, vestibular, or visual disorders that may affect balance
- History of other orthopedic diseases or trauma
- Presence of musculoskeletal disorders or cardiovascular comorbidities
- History of physiotherapy, rehabilitation, or surgical intervention within the past 6 months
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Dynamic Postural Control-ALFA Stabilometric Platform
Time frame: Baseline
Dynamic balance performance will be assessed using the ALFA Stabilometric Platform. The device software calculates an overall dynamic balance performance score based on center of pressure. Higher scores indicating better dynamic postural control performance.
5 secondary outcomes
Static Balance Performance
Time frame: Baseline
Isokinetic Muscle Strength
Time frame: Baseline
Isokinetic Muscle Endurance
Time frame: Baseline
Pain Intensity
Time frame: Baseline
Kinesiophobia
Time frame: Baseline
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Healthy and Chronic Ankle Instability, CAI, run by Biruni University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 18 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Dynamic Postural Control-ALFA Stabilometric Platform (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Aug 2026.