Chronic Ankle Instability, CAINCT07421492
Postural Control in Amateur Footballers With Chronic Ankle Instability
An observational study of Chronic Ankle Instability, CAI, run by Igdir University at 1 site in Turkey (Türkiye).
Trial summary
This study will investigate static and dynamic postural control characteristics in male amateur football players with chronic ankle instability (CAI) compared with football players without ankle instability. Read more about this study
- Who is it for?
- Ages 18 to 45 years, men only
- Conditions the study is for
- Chronic Ankle Instability, CAI
- What is being tested?
- Dynamic stabilization with Tecnobody D-Wall, Static Balance Test with Tecnobody D-Wall and Cumberland Ankle Instability Tool
- How many people
- 28 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Feb 2026to 15 Mar 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- Men only
- Adult
Study population: Male amateur football players competing in a regional league, including athletes with and without chronic ankle instability.
Who may be able to join
- Male amateur football players with at least 2 years of competitive participation and ≥5 years of regular sports activity
- Weekly football training volume of at least 3 hours
- For the CAI group: history of ≥1 significant lateral ankle sprain occurring ≥12 months before testing that caused pain, swelling, and temporary interruption of sports participation
- Presence of ≥2 episodes of giving-way or perceived ankle instability within the previous 6 months
- CAIT score ≤24 for classification as chronic ankle instability
- For the control group: no history of ankle sprain or perceived ankle instability and CAIT score ≥25
- Participants free from ankle pain and acute inflammation at the time of assessment
Who cannot join
- History of lower-extremity fracture or surgical intervention
- Musculoskeletal injury of the knee, hip, or spine within the last 3 months
- Diagnosed vestibular disorder or systemic balance impairment unrelated to the ankle
- Active ankle pain or acute inflammatory symptoms at the time of testing
- Any cardiovascular or systemic disease limiting safe participation in testing
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Static and Dynamic Postural Control in Amateur Footballers With Chronic Ankle Instability: A Machine-Learning-Based Injury Risk Profiling Approach
This study will investigate static and dynamic postural control characteristics in male amateur football players with chronic ankle instability (CAI) compared with football players without ankle instability. Participants will undergo standardized biomechanical assessments using a force-platform-based postural analysis system to quantify postural sway under eyes-open and eyes-closed conditions and to evaluate direction-specific limits of stability performance.
In addition to conventional between-group comparisons, objective balance and stabilization variables will be used to develop supervised machine-learning classification models. These models will examine whether athletes demonstrating CAI-like functional patterns can be identified based solely on biomechanical performance data, independent of self-reported instability questionnaires.
Read more
The results are expected to enhance understanding of neuromuscular control deficits associated with chronic ankle instability and to support the development of objective, performance-based assessment approaches for football players.
The aim of this study is to determine the differences in static and dynamic postural control between amateur football players with and without chronic ankle instability and to evaluate whether multidimensional biomechanical balance parameters can be used to objectively characterize CAI-related functional profiles using machine-learning-based analysis.
- Conditions
- Chronic Ankle Instability, CAI
- Being tested
- Dynamic stabilization with Tecnobody D-Wall, Static Balance Test with Tecnobody D-Wall, Cumberland Ankle Instability Tool
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Dynamic stabilization with Tecnobody D-WallOther
Participants will undergo a non-invasive dynamic balance assessment using a force-platform-based postural analysis system. While standing on the platform, they will intentionally shift their center of pressure toward visual targets in multiple directions to evaluate voluntary postural control within stability limits. The test records total stability performance and directional control (%), test duration (s), and trunk deviation (°), reflecting proprioception and ankle stabilization capacity.
Static Balance Test with Tecnobody D-WallOther
Participants will perform a static postural stability test on a force-platform while standing quietly in an upright position under eyes-open and eyes-closed conditions. The system will measure postural sway area (mm²) to quantify the ability to maintain balance with and without visual input. This assessment evaluates sensory integration and proprioceptive control associated with ankle stability.
Cumberland Ankle Instability ToolOther
The Cumberland Ankle Instability Tool is a validated self-reported questionnaire consisting of 9 items used to assess perceived ankle instability during daily and sport-related activities. It evaluates symptoms such as episodes of giving-way, pain, and functional control of the ankle, with total scores ranging from 0 to 30 (lower scores indicate greater instability). The CAIT is used as a screening questionnaire to classify participants according to the presence or absence of chronic ankle instability.
What is being measured
The primary outcome is the main question the study is designed to answer.
Limits of Stability Total Score (%) During Force-Platform Dynamic Postural Control Assessment at Baseline
Dynamic postural control will be evaluated using the limited stabilization (limits of stability) test performed on a force-platform-based postural analysis system. The total limits of stability score (%) reflects the participant's ability to voluntarily control the center of pressure within stability boundaries, with lower values indicating impaired neuromuscular ankle stabilization.
Measured: Baseline (single laboratory assessment session)
Secondary outcomes (1)
Postural Sway Area (mm²) During Static Balance Assessment With Eyes Open and Eyes Closed at Baseline
Measured: Baseline (single laboratory assessment session)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Feb 2026
- Study start1 Feb 2026
- Primary completion28 Feb 2026 (estimated)
- Study completion15 Mar 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Chronic Ankle Instability, CAIStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 28 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Igdir University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Erkan Güven, Igdir University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07421492
- Sponsor's protocol ID
- 02.01.2026 - 2026/1
- Status last verified
- Feb 2026
- First submitted
- 12 Feb 2026
- Last updated
- 19 Feb 2026
- Results posted
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Static and Dynamic Postural Control in Amateur Footballers With Chronic Ankle Instability: A Machine-Learning-Based Injury Risk Profiling Approach
- ClinicalTrials.gov ID
- NCT07421492
- Acronym / sponsor ID
- 02.01.2026 - 2026/1
- Conditions
- Chronic Ankle Instability, CAI
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 28 participants (estimated)
- Lead sponsor
- Igdir UniversityUniversity, hospital or other
- Study start
- 1 Feb 2026 (actual)
- Primary completion
- 28 Feb 2026 (estimated)
- Study completion
- 15 Mar 2026 (estimated)
- First posted
- 19 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will investigate static and dynamic postural control characteristics in male amateur football players with chronic ankle instability (CAI) compared with football players without ankle instability. Participants will undergo standardized biomechanical assessments using a force-platform-based postural analysis system to quantify postural sway under eyes-open and eyes-closed conditions and to evaluate direction-specific limits of stability performance.
In addition to conventional between-group comparisons, objective balance and stabilization variables will be used to develop supervised machine-learning classification models. These models will examine whether athletes demonstrating CAI-like functional patterns can be identified based solely on biomechanical performance data, independent of self-reported instability questionnaires.
The results are expected to enhance understanding of neuromuscular control deficits associated with chronic ankle instability and to support the development of objective, performance-based assessment approaches for football players.
The aim of this study is to determine the differences in static and dynamic postural control between amateur football players with and without chronic ankle instability and to evaluate whether multidimensional biomechanical balance parameters can be used to objectively characterize CAI-related functional profiles using machine-learning-based analysis.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 to 45 years
- Sex
- Male only
- Age groups
- Adult
- Study population
- Male amateur football players competing in a regional league, including athletes with and without chronic ankle instability.
Key inclusion criteria (7 listed)
- Male amateur football players with at least 2 years of competitive participation and ≥5 years of regular sports activity
- Weekly football training volume of at least 3 hours
- For the CAI group: history of ≥1 significant lateral ankle sprain occurring ≥12 months before testing that caused pain, swelling, and temporary interruption of sports participation
- Presence of ≥2 episodes of giving-way or perceived ankle instability within the previous 6 months
- CAIT score ≤24 for classification as chronic ankle instability
Key exclusion criteria (5 listed)
- History of lower-extremity fracture or surgical intervention
- Musculoskeletal injury of the knee, hip, or spine within the last 3 months
- Diagnosed vestibular disorder or systemic balance impairment unrelated to the ankle
- Active ankle pain or acute inflammatory symptoms at the time of testing
- Any cardiovascular or systemic disease limiting safe participation in testing
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Dynamic stabilization with Tecnobody D-WallParticipants will undergo a non-invasive dynamic balance assessment using a force-platform-based postural analysis system. While standing on the platform, they will intentionally shift their center of pressure toward visual targets in multiple directions to evaluate voluntary postural control within stability limits. The test records total stability performance and directional control (%), test duration (s), and trunk deviation (°), reflecting proprioception and ankle stabilization capacity. | Other | – |
| Static Balance Test with Tecnobody D-WallParticipants will perform a static postural stability test on a force-platform while standing quietly in an upright position under eyes-open and eyes-closed conditions. The system will measure postural sway area (mm²) to quantify the ability to maintain balance with and without visual input. This assessment evaluates sensory integration and proprioceptive control associated with ankle stability. | Other | – |
| Cumberland Ankle Instability ToolThe Cumberland Ankle Instability Tool is a validated self-reported questionnaire consisting of 9 items used to assess perceived ankle instability during daily and sport-related activities. It evaluates symptoms such as episodes of giving-way, pain, and functional control of the ankle, with total scores ranging from 0 to 30 (lower scores indicate greater instability). The CAIT is used as a screening questionnaire to classify participants according to the presence or absence of chronic ankle instability. | Other | – |
Primary outcome
Limits of Stability Total Score (%) During Force-Platform Dynamic Postural Control Assessment at Baseline
Time frame: Baseline (single laboratory assessment session)
Dynamic postural control will be evaluated using the limited stabilization (limits of stability) test performed on a force-platform-based postural analysis system. The total limits of stability score (%) reflects the participant's ability to voluntarily control the center of pressure within stability boundaries, with lower values indicating impaired neuromuscular ankle stabilization.
1 secondary outcome
Postural Sway Area (mm²) During Static Balance Assessment With Eyes Open and Eyes Closed at Baseline
Time frame: Baseline (single laboratory assessment session)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Feb 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Chronic Ankle Instability, CAI, run by Igdir University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 19 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Limits of Stability Total Score (%) During Force-Platform Dynamic Postural Control Assessment at Baseline (time frame: Baseline (single laboratory assessment session)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Feb 2026.