Kidney StoneNCT07421843
Short Interval Versus Long Interval Repeated Extracorporeal Shockwave Lithotripsy (ESWL) for 8-15 mm Renal Stones.
A study testing Extracorporeal shockwave lithotripsy (ESWL) in people with Kidney Stone, run by Region Skane at 2 sites in Sweden.
Trial summary
Extracorporeal shockwave lithotripsy (ESWL) is one way to treat renal stones. In this clinical trial our goal is to evaluate if two ESWL the same week is equal good and safe to two ESWL 3 weeks regarding renal stones 8-15 mm. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Kidney Stone
- What is being tested?
- Extracorporeal shockwave lithotripsy (ESWL)
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 600 participants
- Where
- 2 sitesSweden
- Study dates
- 4 Oct 2022to 1 Apr 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Inclusion Criteria: All patients with a renal stone 8-15 mm who are planned for intervention -
Exclusion Criteria: Those who decline to participate, those who are put under guardianship or is less than 18 years old.
-
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Sweden2 sites
Department of Urology
Helsingborg
Department of Urology, KI Huddinge
Stockholm
About this study
Official title: Double Extracorporeal Shockwave Lithotripsy for Renal Stones.
Extracorporeal shockwave lithotripsy (ESWL) is one way to treat renal stones. In this clinical trial our goal is to evaluate if two ESWL the same week is equal good and safe to two ESWL 3 weeks regarding renal stones 8-15 mm.
Read the detailed description
All patients with a renal stone 8-15 mm are asked to participate. If they give consent they are randomized to ESWL with an interval of 2 days or 3 weeks. Data regarding age, gender, stone size, Hounsfield unit, skin to stone distance, urine culture, results from the follow up CT and need for auxillary interventions are extraced from the medical records.
- Conditions
- Kidney Stone
- Being tested
- Extracorporeal shockwave lithotripsy (ESWL)
- Medical subject headings
- Kidney Calculi
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Extracorporeal shockwave lithotripsy (ESWL)Procedure or surgery
ESWL, two treatments with an interval of two days or three weeks.
| Study group | Role | What they receive |
|---|---|---|
| ESWL, two days | Active comparator | Not described Receives: Procedure: Extracorporeal shockwave lithotripsy (ESWL) |
| ESWL, three weeks | Active comparator | Not described Receives: Procedure: Extracorporeal shockwave lithotripsy (ESWL) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Time to stone free status
Number of days from the day the treatment starts until the end of follow up.
Measured: From enrollment until closure
Complications
Are there any differences in complications
Measured: From enrollment until closure
Number of participants considered stone free at follow up
Number of participants who are stone free at the follow up after two ESWL. Stone status will be assessed with computer tomography.
Measured: From enrollment until closure.
Secondary outcomes (1)
Participant´s experiences
Participant´s experiences, quality of life questionnaire. Most questions were structured as yes/ no items or included three to four predefined response options.
Measured: From enrollment until closure
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Feb 2026
- Study start4 Oct 2022
- Primary completion1 Apr 2026 (estimated)
- Study completion1 Apr 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Kidney StoneStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Randomisation to ESWL with an interval of two days and with an interval of three weeks.
- Masking
- None (open label)
- Enrolment
- 600 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Region Skane
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Magnus Wagenius, MD, PhD, Principal investigator, University of Lund
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07421843
- Sponsor's protocol ID
- 2022-00035-01
- Status last verified
- Jan 2026
- First submitted
- 20 Jan 2026
- Last updated
- 19 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Double Extracorporeal Shockwave Lithotripsy for Renal Stones.
- ClinicalTrials.gov ID
- NCT07421843
- Acronym / sponsor ID
- 2022-00035-01
- Conditions
- Kidney Stone
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 600 participants (estimated)
- Lead sponsor
- Region SkaneUniversity, hospital or other
- Study start
- 4 Oct 2022 (actual)
- Primary completion
- 1 Apr 2026 (estimated)
- Study completion
- 1 Apr 2026 (estimated)
- First posted
- 19 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Extracorporeal shockwave lithotripsy (ESWL) is one way to treat renal stones. In this clinical trial our goal is to evaluate if two ESWL the same week is equal good and safe to two ESWL 3 weeks regarding renal stones 8-15 mm.
Detailed description
All patients with a renal stone 8-15 mm are asked to participate. If they give consent they are randomized to ESWL with an interval of 2 days or 3 weeks. Data regarding age, gender, stone size, Hounsfield unit, skin to stone distance, urine culture, results from the follow up CT and need for auxillary interventions are extraced from the medical records.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Randomisation to ESWL with an interval of two days and with an interval of three weeks.
| Arm | Type | Receives |
|---|---|---|
| ESWL, two days | Active comparator | Procedure: Extracorporeal shockwave lithotripsy (ESWL) |
| ESWL, three weeks | Active comparator | Procedure: Extracorporeal shockwave lithotripsy (ESWL) |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Extracorporeal shockwave lithotripsy (ESWL)ESWL, two treatments with an interval of two days or three weeks. | Procedure or surgery | ESWL, three weeks, ESWL, two days |
Primary outcome
Time to stone free status
Time frame: From enrollment until closure
Number of days from the day the treatment starts until the end of follow up.
Complications
Time frame: From enrollment until closure
Are there any differences in complications
Number of participants considered stone free at follow up
Time frame: From enrollment until closure.
Number of participants who are stone free at the follow up after two ESWL. Stone status will be assessed with computer tomography.
1 secondary outcome
Participant´s experiences
Time frame: From enrollment until closure
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Feb 2026.
- Individual participant dataSharing planned: No
Related trials for Kidney Stone
Recruiting
Randomized Controlled Trial of Miniaturized Percutaneous Nephrolithotomy With Vacuum-Assisted Access Sheaths Versus Conventional Sheaths for Treatment of Nephrolithiasis
Kidney Stone
Not yet recruitingObservational study
Novel Antimicrobial Solution to Prevent Infections
Kidney Stone, Infection
Not yet recruiting
DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones
Kidney Stones, Nephrolithiasis
RecruitingPhase 3
Trial to Assess the Efficacy of EMPAgliflozin and Personalized Dietary Counseling for Kidney STONE Prevention
Kidney Stone, Nephrolithiasis
RecruitingObservational study
Renal Stone Treatment Global Registry
Urolithiasis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Magnus Wagenius, MD, PhD principal investigator
University of Lund
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Extracorporeal shockwave lithotripsy (ESWL) in people with Kidney Stone, run by Region Skane at 2 sites in Sweden.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 19 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Sweden. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Time to stone free status (time frame: From enrollment until closure). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Feb 2026.