Atelectasis, PostoperativeNCT07432477
Single-step vs Stepwise Lung Recruitment Maneuvers After Cardiopulmonary Bypass
A study testing Single Step Lung Recruitment Maneuver and Stepwise Lung Recruitment Maneuver in people with Atelectasis, Postoperative, run by Ondokuz Mayıs University at 1 site in Turkey (Türkiye).
Trial summary
This prospective randomized controlled trial aims to compare the hemodynamic and pulmonary effects of single-step and stepwise lung recruitment maneuvers in adult patients undergoing elective cardiac surgery with cardiopulmonary bypass. Read more about this study
- Who is it for?
- Ages 18 to 80 years
- Conditions the study is for
- Atelectasis, Postoperative
- What is being tested?
- Single Step Lung Recruitment Maneuver and Stepwise Lung Recruitment Maneuver
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 52 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Feb 2026to 1 May 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age 18-80 years
- ASA (American Society of Anesthesiologists) II-IV
- Patients undergoing elective cardiac surgery (coronary artery bypass grafting, mitral valve replacement, aortic valve replacement)
Who cannot join
- Emergency surgery
- Presence of perioperative arrhythmia
- <35% left ventricular ejection fraction
- >50 mmHg systolic pulmonary artery pressure
- Known chronic obstructive pulmonary disease or interstitial lung disease
- Pneumothorax
Show all 12Show fewer
- Mean arterial pressure <60 mmHg during recruitment maneuver
- New York Heart Association (NYHA) class III-IV heart failure
- Advanced cardiomyopathy or severe mitral regurgitation
- Cross-clamp time longer than 2 hours
- Requirement for high-dose inotropic or vasopressor support
- Patients who cannot be extubated after postoperative 24 hours
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Ondokuz Mayıs University, Faculty of Medicine
Samsun
Burhan Dost, MD, +903623121919, burhandost@hotmail.com
Hilal H Kandemir, MD, +903623121919, hhilal.kandemir@gmail.com
About this study
Official title: Comparison of Hemodynamic and Pulmonary Outcomes Between Single-Step and Stepwise Lung Recruitment Maneuvers After Cardiopulmonary Bypass: A Randomized Controlled Trial
This prospective randomized controlled trial aims to compare the hemodynamic and pulmonary effects of single-step and stepwise lung recruitment maneuvers in adult patients undergoing elective cardiac surgery with cardiopulmonary bypass. After separation from cardiopulmonary bypass, patients will be randomized to receive either a single-step sustained inflation recruitment maneuver or a stepwise incremental recruitment maneuver, both combined with 8 cmH₂O positive end-expiratory pressure. The primary outcome is the change in cardiac index before and after the recruitment maneuver. Secondary outcomes include lung ultrasound atelectasis score, and hemodynamic parameters.
Read the detailed description
Atelectasis frequently develops after cardiopulmonary bypass due to lung ischemia-reperfusion injury, inflammatory response, and mechanical factors related to cardiac surgery. Lung recruitment maneuvers are commonly used to improve lung aeration and oxygenation; however, increased intrathoracic pressure during recruitment may negatively affect venous return and cardiac output.
In this randomized controlled trial, adult patients undergoing elective open-heart surgery with cardiopulmonary bypass will be allocated to receive either a single-step sustained inflation recruitment maneuver or a stepwise incremental recruitment maneuver, both combined with 8 cmH₂O positive end-expiratory pressure after separation from cardiopulmonary bypass. Hemodynamic variables, particularly cardiac index, will be assessed before and after recruitment. Pulmonary effects will be evaluated using lung ultrasound atelectasis scoring and arterial blood gas analysis. The study aims to identify the recruitment strategy that provides optimal pulmonary benefits while preserving hemodynamic stability in this high-risk patient population.
- Conditions
- Atelectasis, Postoperative
- Being tested
- Single Step Lung Recruitment Maneuver, Stepwise Lung Recruitment Maneuver
- Keywords
- cardiopulmonary bypass, lung recruitment maneuver, atelectasis, cardiac surgery, cardiac index, hemodynamics, lung ultrasound, positive end-expiratory pressure
- Medical subject headings
- Pulmonary Atelectasis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Single Step Lung Recruitment ManeuverProcedure or surgery
A sustained inflation lung recruitment maneuver with an airway pressure of 30 cmH₂O applied for 30 seconds after separation from cardiopulmonary bypass, combined with 8 cmH₂O positive end-expiratory pressure.
Stepwise Lung Recruitment ManeuverProcedure or surgery
A stepwise lung recruitment maneuver in which airway pressure is increased by 5 cmH₂O every 5 seconds up to 30 cmH₂O and then decreased in the same manner after separation from cardiopulmonary bypass, combined with 8 cmH₂O positive end-expiratory pressure.
| Study group | Role | What they receive |
|---|---|---|
| Grup Single Step | Active comparator | A single step lung recruitment maneuver for 30 seconds will be applied Receives: Procedure: Single Step Lung Recruitment Maneuver |
| Grup Stepwise | Active comparator | A stepwise recruitment maneuver will be applied. Receives: Procedure: Stepwise Lung Recruitment Maneuver |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in Cardiac Index
Difference in cardiac index measured before and after the lung recruitment maneuver.
Measured: Intraoperative period
Secondary outcomes (18)
The heart rate measurement
Heart rate will be recorded preoperatively; after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
The mean arterial pressure measurement
Mean arterial pressure will be recorded preoperatively; after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
Systemic vascular resistance index measurement
Systemic vascular resistance index will be recorded preoperatively; after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
Stroke volume variation
Dynamic hemodynamic parameters, including stroke volume variation (SVV, %), will be recorded as separate variables using invasive arterial waveform analysis. Measurements will be obtained after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
Arterial elastance
Dynamic hemodynamic parameters including arterial elastance (Ea, mmHg/mL), will be recorded as separate variables using invasive arterial waveform analysis. Measurements will be obtained after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
Contractility
Dynamic hemodynamic parameters, including cardiac contractility indices, will be recorded as separate variables using invasive arterial waveform analysis. Measurements will be obtained after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
Lung ultrasound atelectasis score
Change in lung ultrasound atelectasis score before and after the recruitment maneuver. Lung aeration was assessed using a 12-region quantitative lung ultrasound (LUS) score (0-36) based on the ESICM-ESPNIC consensus. Each region was graded 0-3 (0 = normal aeration; 1 = mild loss with B-lines/subpleural changes ≤50%; 2 = moderate loss with coalescent B-lines or small consolidation <2-2.5 cm; 3 = severe loss with large consolidation ≥2-2.5 cm). Higher scores indicated greater aeration loss.
Measured: Intraoperative period and postoperative day 1
Peak airway pressure
Peak airway pressure (Ppeak), measured in cmH₂O, will be recorded after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
Plateau pressure
plateau pressure (Pplat), measured in cmH₂O, will be recorded after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
Dynamic lung compliance
Dynamic lung compliance (Cdyn), expressed as mL/cmH₂O, will be recorded after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
Driving pressure
Driving pressure, calculated as plateau pressure minus positive end-expiratory pressure (Pplat - PEEP) and expressed in cmH₂O, will be recorded after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
Positive end-expiratory pressure
Positive end-expiratory pressure (PEEP), measured in cmH₂O, will be recorded after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
Arterial pH
Arterial pH (unitless) measured by arterial blood gas analysis will be recorded after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
Partial pressure of arterial oxygen
Partial pressure of arterial oxygen (PaO₂, mmHg) measured by arterial blood gas analysis will be recorded after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
Partial pressure of arterial carbon dioxide
Partial pressure of arterial carbon dioxide (PaCO₂, mmHg) measured by arterial blood gas analysis will be recorded after induction; immediately before the recruitment maneuver (RM); during RM at the point of maximum airway pressure; at the end of RM; 30 minutes after RM; at postoperative hour 1; and immediately after extubation.
Measured: Intraoperative period and postoperative day 1.
Serum lactate level
Change in serum lactate level measured perioperatively.
Measured: Intraoperative period and postoperative day 1
Extubation time
After the operation, the time until the patient is extubated will be recorded.
Measured: Postoperative day 1
Length of intensive care unit stay (ICU)
Time from ICU admission to ICU discharge.
Measured: The time from admission to the ICU to the time of discharge to the hospital ward; during the hospital stay, an average of 7 days
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Feb 2026
- Study start15 Feb 2026
- Primary completion1 Feb 2027 (estimated)
- Study completion1 May 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for Atelectasis, PostoperativeStudies of the same condition, open and under way.
- More trials run by Ondokuz Mayıs UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomized in a 1:1 ratio to receive either a single-step sustained inflation lung recruitment maneuver or a stepwise incremental lung recruitment maneuver after separation from cardiopulmonary bypass.
- Masking
- Quadruple blind
- Who is masked
- Participant, Care provider, Investigator, Outcomes assessor
- Enrolment
- 52 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Ondokuz Mayıs University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, BURHAN DOST, Ondokuz Mayıs University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07432477
- Sponsor's protocol ID
- LRMCPB000
- Status last verified
- Jun 2026
- First submitted
- 26 Jan 2026
- Last updated
- 1 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Longo S, Siri J, Acosta C, Palencia A, Echegaray A, Chiotti I, Parisi A, Ricci L, Natal M, Suarez-Sipmann F, Tusman G. Lung recruitment improves right ventricular performance after cardiopulmonary bypass: A randomised controlled trial. Eur J Anaesthesiol. 2017 Feb;34(2):66-74. doi: 10.1097/EJA.0000000000000559.
PubMed 27861261Celebi S, Koner O, Menda F, Korkut K, Suzer K, Cakar N. The pulmonary and hemodynamic effects of two different recruitment maneuvers after cardiac surgery. Anesth Analg. 2007 Feb;104(2):384-90. doi: 10.1213/01.ane.0000252967.33414.44.
PubMed 17242096Myatra SN. Hemodynamic effects of alveolar recruitment maneuvres in the operating room: Proceed with caution. J Anaesthesiol Clin Pharmacol. 2019 Oct-Dec;35(4):431-433. doi: 10.4103/joacp.JOACP_223_19. No abstract available.
PubMed 31920224Nielsen J, Ostergaard M, Kjaergaard J, Tingleff J, Berthelsen PG, Nygard E, Larsson A. Lung recruitment maneuver depresses central hemodynamics in patients following cardiac surgery. Intensive Care Med. 2005 Sep;31(9):1189-94. doi: 10.1007/s00134-005-2732-z. Epub 2005 Aug 12.
PubMed 16096751Mongodi S, Cortegiani A, Alonso-Ojembarrena A, Biasucci DG, Bos LDJ, Bouhemad B, Cantinotti M, Ciuca I, Corradi F, Girard M, Gregorio-Hernandez R, Gualano MR, Mojoli F, Ntoumenopoulos G, Pisani L, Raimondi F, Rodriguez-Fanjul J, Savoia M, Smit MR, Tuinman PR, Zieleskiewicz L, De Luca D. ESICM-ESPNIC international expert consensus on quantitative lung ultrasound in intensive care. Intensive Care Med. 2025 Jun;51(6):1022-1049. doi: 10.1007/s00134-025-07932-y. Epub 2025 May 12.
PubMed 40353867
Study at a glance
From the registry record, last updated by the sponsor on 1 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Hemodynamic and Pulmonary Outcomes Between Single-Step and Stepwise Lung Recruitment Maneuvers After Cardiopulmonary Bypass: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07432477
- Acronym / sponsor ID
- LRMCPB000
- Conditions
- Atelectasis, Postoperative
- Keywords
- cardiopulmonary bypass, lung recruitment maneuver, atelectasis, cardiac surgery, cardiac index, hemodynamics, lung ultrasound, positive end-expiratory pressure
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 52 participants (estimated)
- Lead sponsor
- Ondokuz Mayıs UniversityUniversity, hospital or other
- Study start
- 15 Feb 2026 (actual)
- Primary completion
- 1 Feb 2027 (estimated)
- Study completion
- 1 May 2027 (estimated)
- First posted
- 25 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This prospective randomized controlled trial aims to compare the hemodynamic and pulmonary effects of single-step and stepwise lung recruitment maneuvers in adult patients undergoing elective cardiac surgery with cardiopulmonary bypass. After separation from cardiopulmonary bypass, patients will be randomized to receive either a single-step sustained inflation recruitment maneuver or a stepwise incremental recruitment maneuver, both combined with 8 cmH₂O positive end-expiratory pressure. The primary outcome is the change in cardiac index before and after the recruitment maneuver. Secondary outcomes include lung ultrasound atelectasis score, and hemodynamic parameters.
Detailed description
Atelectasis frequently develops after cardiopulmonary bypass due to lung ischemia-reperfusion injury, inflammatory response, and mechanical factors related to cardiac surgery. Lung recruitment maneuvers are commonly used to improve lung aeration and oxygenation; however, increased intrathoracic pressure during recruitment may negatively affect venous return and cardiac output.
In this randomized controlled trial, adult patients undergoing elective open-heart surgery with cardiopulmonary bypass will be allocated to receive either a single-step sustained inflation recruitment maneuver or a stepwise incremental recruitment maneuver, both combined with 8 cmH₂O positive end-expiratory pressure after separation from cardiopulmonary bypass. Hemodynamic variables, particularly cardiac index, will be assessed before and after recruitment. Pulmonary effects will be evaluated using lung ultrasound atelectasis scoring and arterial blood gas analysis. The study aims to identify the recruitment strategy that provides optimal pulmonary benefits while preserving hemodynamic stability in this high-risk patient population.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Quadruple blind (participant, care provider, investigator, outcomes assessor)
- Number of arms
- 2
- Model description
- Participants will be randomized in a 1:1 ratio to receive either a single-step sustained inflation lung recruitment maneuver or a stepwise incremental lung recruitment maneuver after separation from cardiopulmonary bypass.
| Arm | Type | Receives |
|---|---|---|
| Grup Single Step | Active comparator | Procedure: Single Step Lung Recruitment ManeuverA single step lung recruitment maneuver for 30 seconds will be applied |
| Grup Stepwise | Active comparator | Procedure: Stepwise Lung Recruitment ManeuverA stepwise recruitment maneuver will be applied. |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Age 18-80 years
- ASA (American Society of Anesthesiologists) II-IV
- Patients undergoing elective cardiac surgery (coronary artery bypass grafting, mitral valve replacement, aortic valve replacement)
Key exclusion criteria (12 listed)
- Emergency surgery
- Presence of perioperative arrhythmia
- <35% left ventricular ejection fraction
- >50 mmHg systolic pulmonary artery pressure
- Known chronic obstructive pulmonary disease or interstitial lung disease
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Single Step Lung Recruitment ManeuverA sustained inflation lung recruitment maneuver with an airway pressure of 30 cmH₂O applied for 30 seconds after separation from cardiopulmonary bypass, combined with 8 cmH₂O positive end-expiratory pressure. | Procedure or surgery | Grup Single Step |
| Stepwise Lung Recruitment ManeuverA stepwise lung recruitment maneuver in which airway pressure is increased by 5 cmH₂O every 5 seconds up to 30 cmH₂O and then decreased in the same manner after separation from cardiopulmonary bypass, combined with 8 cmH₂O positive end-expiratory pressure. | Procedure or surgery | Grup Stepwise |
Primary outcome
Change in Cardiac Index
Time frame: Intraoperative period
Difference in cardiac index measured before and after the lung recruitment maneuver.
18 secondary outcomes
The heart rate measurement
Time frame: Intraoperative period and postoperative day 1.
The mean arterial pressure measurement
Time frame: Intraoperative period and postoperative day 1.
Systemic vascular resistance index measurement
Time frame: Intraoperative period and postoperative day 1.
Stroke volume variation
Time frame: Intraoperative period and postoperative day 1.
Arterial elastance
Time frame: Intraoperative period and postoperative day 1.
Contractility
Time frame: Intraoperative period and postoperative day 1.
Lung ultrasound atelectasis score
Time frame: Intraoperative period and postoperative day 1
Peak airway pressure
Time frame: Intraoperative period and postoperative day 1.
Plateau pressure
Time frame: Intraoperative period and postoperative day 1.
Dynamic lung compliance
Time frame: Intraoperative period and postoperative day 1.
Driving pressure
Time frame: Intraoperative period and postoperative day 1.
Positive end-expiratory pressure
Time frame: Intraoperative period and postoperative day 1.
Arterial pH
Time frame: Intraoperative period and postoperative day 1.
Partial pressure of arterial oxygen
Time frame: Intraoperative period and postoperative day 1.
Partial pressure of arterial carbon dioxide
Time frame: Intraoperative period and postoperative day 1.
Serum lactate level
Time frame: Intraoperative period and postoperative day 1
Extubation time
Time frame: Postoperative day 1
Length of intensive care unit stay (ICU)
Time frame: The time from admission to the ICU to the time of discharge to the hospital ward; during the hospital stay, an average of 7 days
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Jul 2026.
- Background: PubMed 27861261Longo S, Siri J, Acosta C, Palencia A, Echegaray A, Chiotti I, Parisi A, Ricci L, Natal M, Suarez-Sipmann F, Tusman G. Lung recruitment improves right ventricular performance after cardiopulmonary bypass: A randomised controlled trial. Eur J Anaesthesiol. 2017 Feb;34(2):66-74. doi: 10.1097/EJA.0000000000000559.
- Background: PubMed 17242096Celebi S, Koner O, Menda F, Korkut K, Suzer K, Cakar N. The pulmonary and hemodynamic effects of two different recruitment maneuvers after cardiac surgery. Anesth Analg. 2007 Feb;104(2):384-90. doi: 10.1213/01.ane.0000252967.33414.44.
- Background: PubMed 31920224Myatra SN. Hemodynamic effects of alveolar recruitment maneuvres in the operating room: Proceed with caution. J Anaesthesiol Clin Pharmacol. 2019 Oct-Dec;35(4):431-433. doi: 10.4103/joacp.JOACP_223_19. No abstract available.
- Background: PubMed 16096751Nielsen J, Ostergaard M, Kjaergaard J, Tingleff J, Berthelsen PG, Nygard E, Larsson A. Lung recruitment maneuver depresses central hemodynamics in patients following cardiac surgery. Intensive Care Med. 2005 Sep;31(9):1189-94. doi: 10.1007/s00134-005-2732-z. Epub 2005 Aug 12.
- Background: PubMed 40353867Mongodi S, Cortegiani A, Alonso-Ojembarrena A, Biasucci DG, Bos LDJ, Bouhemad B, Cantinotti M, Ciuca I, Corradi F, Girard M, Gregorio-Hernandez R, Gualano MR, Mojoli F, Ntoumenopoulos G, Pisani L, Raimondi F, Rodriguez-Fanjul J, Savoia M, Smit MR, Tuinman PR, Zieleskiewicz L, De Luca D. ESICM-ESPNIC international expert consensus on quantitative lung ultrasound in intensive care. Intensive Care Med. 2025 Jun;51(6):1022-1049. doi: 10.1007/s00134-025-07932-y. Epub 2025 May 12.
Related trials for Atelectasis, Postoperative
Active, not recruiting
Stepwise PEEP vs Sustained Inflation in Bariatric Surgery Patients
Recruitment, Bariatric Surgery Candidate
Not yet recruiting
Bedside Assessment of Right Ventricular Output Lying in Prone Or Supine
Right Ventricular Function, Prone Position
Not yet recruiting
Brief Bronchial Suction for Lung Collapse During Uniportal VATS
Lung Collapse, One-lung Ventilation
Enrolling by invitation
Evaluation of the Effectiveness of Lung-Protective Ventilation in Patients Undergoing Laparoscopic Gastrectomy
Postoperative Pulmonary Complications (PPCs), Atelectasis
Not yet recruiting
Flow-Controlled vs. Pressure-Controlled Ventilation in CABG: Effects on Lung Aeration and Diaphragm Function
Coronary Artery Disease, Postoperative Pulmonary Complications
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Single Step Lung Recruitment Maneuver and Stepwise Lung Recruitment Maneuver in people with Atelectasis, Postoperative, run by Ondokuz Mayıs University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 1 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Burhan Dost, MD (+903623121919, burhandost@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in Cardiac Index (time frame: Intraoperative period). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07432477, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Jul 2026.