Oral DiseaseNCT07433374
COMPARISON OF THE EFFICIENCY OF MANUAL SINGLE HEADED AND TRIPLE HEADED TOOTHBRUSHES IN REMOVING DENTAL PLAQUE AND USER EXPERIENCE
A study testing triple headed manual toothbrush and manual single headed toothbrush in people with Oral Disease, run by Dow University of Health Sciences at 1 site in Pakistan.
Trial summary
Background: Poor oral hygiene can be the result of negligence or because people cannot take care of their own oral hygiene due to limited dexterity. Dental plaque results in dental decay and periodontal disease over time. Read more about this study
- Who is it for?
- Ages 21 to 25 yearsHealthy volunteers can take part
- Conditions the study is for
- Oral Disease
- What is being tested?
- triple headed manual toothbrush and manual single headed toothbrush
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 sitePakistan
- Study dates
- 4 Feb 2026to 13 Feb 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 21 to 25 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Accept healthy individuals
- Age group 21-25 years.
- Both males and females.
- Individuals with no active dental or systemic diseases.
- Consenting participants or guardians providing consent for minors
Who cannot join
- 1. Non-consenting individuals or guardians.
- 2. Those with active oral infections or systemic conditions affecting oral health.
- 3. Participants with a recent professional dental cleaning (within 3 months).
- 4. Use of orthodontic appliances or prosthetics that may interfere with toothbrushing performance.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: COMPARISON OF THE EFFICIENCY OF MANUAL AND ELECTRIC TOOTHBRUSHES IN REMOVING DENTAL PLAQUE AND USER EXPERIENCE
Background: Poor oral hygiene can be the result of negligence or because people cannot take care of their own oral hygiene due to limited dexterity. Dental plaque results in dental decay and periodontal disease over time. The importance of good oral hygiene can not be underestimated, not only for maintaining good oral health but also for maintaining general health. The most widespread means of controlling plaque at home is the toothbrush. Toothbrushes are designed in a way so as to remove plaque more efficiently.
Objective: To compare the efficiency of different toothbrushes in removing dental plaque Methodology: This Randomized control study will be carried out at Different schools in Karachi, Pakistan. The duration of this study will be 6 months. In this study, the participants will be recruited using a simple random sampling method. A minimum sample size of 20 was chosen. The participants in this study were invited and included based on the following criteria: Age group 15-50 years. Both males and females. Individuals with no active dental or systemic diseases. Consenting participants or guardians providing consent for minors. The participants were excluded based on non-consenting individuals or guardians. Those with active oral infections or systemic conditions affecting oral health. Participants with a recent professional dental cleaning (within 3 months). Use of orthodontic appliances or prosthetics that may interfere with toothbrushing performance.
- Conditions
- Oral Disease
- Being tested
- triple headed manual toothbrush, manual single headed toothbrush
- Medical subject headings
- Mouth Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
triple headed manual toothbrushDevice
triple -headed manual toothbrush for adults
manual single headed toothbrushDevice
manual sigle headed toothbrush
| Study group | Role | What they receive |
|---|---|---|
| single headed brush | Active comparator | Not described Receives: Device: manual single headed toothbrush |
| triple headed brush | Experimental | Not described Receives: Device: triple headed manual toothbrush |
What is being measured
The primary outcome is the main question the study is designed to answer.
decrease in dental plaque and gingival scores
Scores reduction from pre to post. Mean plaque scores of between 0.1 - 0.5 will be considered normal, and the more the scores indicatea worst case
Measured: 1 month
Secondary outcomes (1)
decrease in gingival scores
Scores reduction from pre to post, the more the scores, the worst is the case, 0.1-0.5 mean gingival scores will be considered normal
Measured: 1 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Feb 2026
- Study start4 Feb 2026
- Primary completion12 Feb 2026
- Study completion13 Feb 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Oral DiseaseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Dow University of Health Sciences
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Maria Moin, Dow University of Health Sciences
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07433374
- Sponsor's protocol ID
- Dow UHS2
- Status last verified
- Feb 2026
- First submitted
- 17 Feb 2026
- Last updated
- 25 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 25 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- COMPARISON OF THE EFFICIENCY OF MANUAL AND ELECTRIC TOOTHBRUSHES IN REMOVING DENTAL PLAQUE AND USER EXPERIENCE
- ClinicalTrials.gov ID
- NCT07433374
- Acronym / sponsor ID
- Dow UHS2
- Conditions
- Oral Disease
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Dow University of Health SciencesUniversity, hospital or other
- Study start
- 4 Feb 2026 (actual)
- Primary completion
- 12 Feb 2026 (actual)
- Study completion
- 13 Feb 2026 (actual)
- First posted
- 25 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Background: Poor oral hygiene can be the result of negligence or because people cannot take care of their own oral hygiene due to limited dexterity. Dental plaque results in dental decay and periodontal disease over time. The importance of good oral hygiene can not be underestimated, not only for maintaining good oral health but also for maintaining general health. The most widespread means of controlling plaque at home is the toothbrush. Toothbrushes are designed in a way so as to remove plaque more efficiently.
Objective: To compare the efficiency of different toothbrushes in removing dental plaque Methodology: This Randomized control study will be carried out at Different schools in Karachi, Pakistan. The duration of this study will be 6 months. In this study, the participants will be recruited using a simple random sampling method. A minimum sample size of 20 was chosen. The participants in this study were invited and included based on the following criteria: Age group 15-50 years. Both males and females. Individuals with no active dental or systemic diseases. Consenting participants or guardians providing consent for minors. The participants were excluded based on non-consenting individuals or guardians. Those with active oral infections or systemic conditions affecting oral health. Participants with a recent professional dental cleaning (within 3 months). Use of orthodontic appliances or prosthetics that may interfere with toothbrushing performance.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| single headed brush | Active comparator | Device: manual single headed toothbrush |
| triple headed brush | Experimental | Device: triple headed manual toothbrush |
Who may qualify
- Ages
- 21 to 25 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Accept healthy individuals
- Age group 21-25 years.
- Both males and females.
- Individuals with no active dental or systemic diseases.
- Consenting participants or guardians providing consent for minors
Key exclusion criteria (4 listed)
- 1. Non-consenting individuals or guardians.
- 2. Those with active oral infections or systemic conditions affecting oral health.
- 3. Participants with a recent professional dental cleaning (within 3 months).
- 4. Use of orthodontic appliances or prosthetics that may interfere with toothbrushing performance.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| triple headed manual toothbrushtriple -headed manual toothbrush for adults | Device | triple headed brush |
| manual single headed toothbrushmanual sigle headed toothbrush | Device | single headed brush |
Primary outcome
decrease in dental plaque and gingival scores
Time frame: 1 month
Scores reduction from pre to post. Mean plaque scores of between 0.1 - 0.5 will be considered normal, and the more the scores indicatea worst case
1 secondary outcome
decrease in gingival scores
Time frame: 1 month
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Feb 2026.
- Individual participant dataSharing planned: No
Related trials for Oral Disease
RecruitingPhase 1/2
Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)
Solid Tumor, Non-Small Cell Lung Cancer
Active, not recruitingPhase 4
Effects of Sequential Therapy With Mexidol® (Intravenous) and Mexidol® FORTE 250 (Oral) on Functional Brain Activity Assessed by Functional Magnetic Resonance Imaging and Biochemical Parameters in Patients With Chronic Cerebral Ischemia: A Comparison of Patients With and Without Metabolic Disorders
Metabolic Abnormalities, Obesity & Overweight
Active, not recruiting
Effect of Probiotics on Insulin Sensitivity in Overweight and Obese Pregnancy
Obesity & Overweight, Gestational Diabetes Mellitus (GDM)
Not yet recruitingPhase 2
Effectiveness of Oxitard Gel Versus Physiotherapeutic and Pharmacological Interventions in Alleviating Oral Submucous Fibrosis: A Phase-II Randomized Control Trial
Oral and Maxillofacial Conditions
Not yet recruitingPhase 1
R-2487 in Patients With Sjogren's Syndrome (SjD)
Sjogren's Syndrome, Sjögren
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing triple headed manual toothbrush and manual single headed toothbrush in people with Oral Disease, run by Dow University of Health Sciences at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 25 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
decrease in dental plaque and gingival scores (time frame: 1 month). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Feb 2026.