Chronic Neck PainNCT07438548

Eye-cervical Re-education and Motor Control Training Program in Chronic Neck Pain

A study testing Eye-cervical Re-education Program and Standardized Physiotherapy Treatment in people with Chronic Neck Pain, run by Riphah International University at 1 site in Pakistan.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record

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Trial summary

The study was conducted to determine the comparative effects of an eye-cervical re-education and motor control training program on pain, range of motion and functional disability in chronic neck pain Read more about this study

Who is it for?: Ages 18 to 50 years
Conditions the study is for: Chronic Neck Pain
What is being tested?: Eye-cervical Re-education Program and Standardized Physiotherapy Treatment
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 52 participants
Where: 1 sitePakistan
Study dates: 13 Jan 2025to 31 Oct 2025
Phase: Interventional
Are there results?: None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 to 50 years
All sexes
No healthy volunteers
Adult

Who may be able to join

Neck pain for minimum 3 months
Pain intensity on NPRS between 4 to 7
Limited neck range of motion
Medical diagnosis (Grade-II Neck pain) as per classification by "Bone and Joint Decade 2000-2010"
Cervical discomfort resulting from repetitive motion or prolonged postures.

Who cannot join

History of neck trauma/Fracture/Surgery/ Whiplash Injury
Systemic illness, rheumatic conditions, inflammatory joint disease
Other spine pathologies Cervical myelopathy / Fibromyalgia / Multiple Sclerosis/ Cervical radiculopathy
Tumor symptoms like high temperature, shivering, night pain

Trial locations and contacts

1 site in 1 country.

Pakistan1 site

Rafiq Medical Center
Lahore, Punjab Province, 05412

Other trials in Pakistan

About this study

Official title: Comparative Effects of an Eye-cervical Re-education and Motor Control Training Program on Pain, Range of Motion and Functional Disability in Chronic Neck Pain

The study was conducted to determine the comparative effects of an eye-cervical re-education and motor control training program on pain, range of motion and functional disability in chronic neck pain

Conditions: Chronic Neck Pain
Being tested: Eye-cervical Re-education Program, Motor Control Training Program, Standardized Physiotherapy Treatment
Keywords: Chronic Neck Pain, Neck Ache, Eye-cervical Re-education, Motor Control Training Program, Functional Disability
Medical subject headings: Neck Pain

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Eye-cervical Re-education ProgramOther
Eye-cervical Re-education program was carried out consisting of 10 proprioceptive reprogramming intervention steps : Activation of eye muscles, Passive cervical mobilization with fixed gaze, Active cervical mobility with directed gaze , Global cervical motion exercise , Neck mobility with the trunk , Head reposition exercise (Active), Head reposition exercise (Passive), Free coordination exercise, Manual resistance coordination exercise and Oculo-cervical coordination with soft stimuli. All exercises were done ten times each. 24 sessions were conducted for 8 weeks, with 3 sessions scheduled every week.
Motor Control Training ProgramOther
Motor Control Training Program was performed in supine position. It consisted of four parts, which include the cranio-cervical flexor exercise; co-contraction of neck flexors and extensors; the cranio-cervical extensor exercise; and the scapular re-education exercises. An air-filled cuff was put behind the neck and the patient tried to make five progressive positions with an increase in ROM i.e. to make improvements in pressure of 22, 24, 26, 28 and eventually 30 mmHg on pressure gauge. All exercises were done ten times each. 24 sessions were conducted for 8 weeks, with 3 sessions scheduled every week.
Standardized Physiotherapy TreatmentOther
Electric Hot pack and TENS having (200 µs pulse-width, 1Hz frequency) were applied for 10 minutes.

Study groups in NCT07438548
Study group	Role	What they receive
Eye-cervical Re-education Program	Experimental	Not described Receives: Other: Eye-cervical Re-education Program; Other: Standardized Physiotherapy Treatment
Motor Control Training Program	Active comparator	Not described Receives: Other: Motor Control Training Program; Other: Standardized Physiotherapy Treatment

What is being measured

The primary outcome is the main question the study is designed to answer.

Numeric Pain Rating Scale
Numeric Pain Rating Scale is a subjective measure using which patient's rate their pain. It consists of 11 points, having an overall score ranging from 0 to 10, where: 0, 1 - 3, 4 - 6, 7 - 10 represents no pain, mild, moderate and the most severe pain respectively
Measured: From enrollment to the end of treatment at 8 weeks
Neck Disability Index in Urdu language
Neck pain disability index is used for the disability of the neck or the impact of neck pain on a person. It consists of 10 questions on pain intensity, personal care, lifting, reading, headaches, concentration, work, driving, sleeping and recreation. Performance in each item is described in 6 stages, from 0 to 5 points. The total of 0-4 points indicate no disability, 5-14 points indicate mild disability, 15-24 points indicate moderate disability, 25-34 points indicate severe disability and 35-50 points indicate complete disability
Measured: From enrollment to the end of treatment at 8 weeks
ROM Cervical spine (Flexion)
Changes in cervical spine flexion ROM at baseline and 8th week of intervention was measured using goniometer.
Measured: From enrollment to the end of treatment at 8 weeks
ROM Cervical Spine (Extension)
Changes in cervical spine extension ROM at baseline and 8th week of intervention was measured using goniometer.
Measured: From enrollment to the end of treatment at 8 weeks
ROM Cervical Spine (Lateral Flexion) Left Side
Changes in cervical spine lateral flexion on left side ROM at baseline and 8th week of intervention was measured using goniometer.
Measured: From enrollment to the end of treatment at 8 weeks
ROM Cervical Spine (Lateral Flexion) Right Side
Changes in cervical spine lateral flexion on right side ROM at baseline and 8th week of intervention was measured using goniometer.
Measured: From enrollment to the end of treatment at 8 weeks
ROM Cervical Spine (Rotation) Left Side
Changes in cervical spine rotation on left side ROM at baseline and 8th week of intervention was measured using goniometer.
Measured: From enrollment to the end of treatment at 8 weeks
ROM Cervical Spine (Rotation) Right Side
Changes in cervical spine rotation on right side ROM at baseline and 8th week of intervention was measured using goniometer.
Measured: From enrollment to the end of treatment at 8 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

13 Jan 202531 Oct 2025

First posted27 Feb 2026
Study start13 Jan 2025
Primary completion31 May 2025
Study completion31 Oct 2025

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Publications (10)Papers the sponsor has linked to this study.
Other trials for Chronic Neck PainStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Single blind
Who is masked: Outcomes assessor
Enrolment: 52 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT07438548
Sponsor's protocol ID: REC/RCR & AHS/24/01102
Status last verified: Feb 2026
First submitted: 23 Feb 2026
Last updated: 27 Feb 2026
Results posted: No
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Publications

Agrawal M, Borkar P. Journal of Population Therapeutics & Clinical Pharmacology. 2010.
Aal NMA, Elkeblawy MA, Amine RAM. Effectiveness of eye-cervical re-education versus motor imagery therapy on chronic neck pain: A randomized controlled trial. Sport TK: revista euroamericana de ciencias del deporte. 2024(13):6.
Bhende R, Shinde S, Jain P. Effect of Integrated Postural Training in Individuals with TextNeck Syndrome. J Kinesiol Exerc Sci. 2024;108:1-18.
Mendes Fernandes T, Mendez-Sanchez R, Puente-Gonzalez AS, Martin-Vallejo FJ, Falla D, Vila-Cha C. A randomized controlled trial on the effects of "Global Postural Re-education" versus neck specific exercise on pain, disability, postural control, and neuromuscular features in women with chronic non-specific neck pain. Eur J Phys Rehabil Med. 2023 Feb;59(1):42-53. doi: 10.23736/S1973-9087.22.07554-2. Epub 2023 Jan 4.
PubMed 36598342
Canli K, Demirkiran G, Can F. The efficiency of tactile discrimination training and oculomotor exercises in people with chronic neck pain: a randomized controlled trial. BMC Musculoskelet Disord. 2025 May 27;26(1):519. doi: 10.1186/s12891-025-08755-0.
PubMed 40420069
Goudarzi L, Ghomashchi H, Vahedi M, Kahlaee AH. Investigating the Effect of Addition of Cervical Proprioceptive Training to Conventional Physiotherapy on Visual, Vestibular and Proprioceptive Dependency of Postural Control in Patients with Chronic Non-Specific Neck Pain: A Randomized Controlled Clinical Trial. Arch Bone Jt Surg. 2024;12(1):36-50. doi: 10.22038/ABJS.2023.74763.3462.
PubMed 38318308
Majcen Rosker Z, Vodicar M, Kristjansson E. Relationship between Cervicocephalic Kinesthetic Sensibility Measured during Dynamic Unpredictable Head Movements and Eye Movement Control or Postural Balance in Neck Pain Patients. Int J Environ Res Public Health. 2022 Jul 9;19(14):8405. doi: 10.3390/ijerph19148405.
PubMed 35886255
Gumuscu BH, Kisa EP, Kara Kaya B, Muammer R. Comparison of three different exercise trainings in patients with chronic neck pain: a randomized controlled study. Korean J Pain. 2023 Apr 1;36(2):242-252. doi: 10.3344/kjp.22371. Epub 2023 Mar 21.
PubMed 36941087
Perez-Cabezas V, Ruiz-Molinero C, Jimenez-Rejano JJ, Chamorro-Moriana G, Gonzalez-Medina G, Chillon-Martinez R. Effectiveness of an Eye-Cervical Re-Education Program in Chronic Neck Pain: A Randomized Clinical Trial. Evid Based Complement Alternat Med. 2020 Feb 26;2020:2760413. doi: 10.1155/2020/2760413. eCollection 2020.
PubMed 32184889
Suvarnnato T, Puntumetakul R, Uthaikhup S, Boucaut R. Effect of specific deep cervical muscle exercises on functional disability, pain intensity, craniovertebral angle, and neck-muscle strength in chronic mechanical neck pain: a randomized controlled trial. J Pain Res. 2019 Mar 7;12:915-925. doi: 10.2147/JPR.S190125. eCollection 2019.
PubMed 30881101

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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Chronic Neck Pain With Mobility Deficits, Chronic Neck Pain With Mobility Deficits (> 3 Months)
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Effects of Instrument-Assisted Soft Tissue Mobilization Versus Post Facilitation Stretch Technique in Chronic Neck Pain
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All Chronic Neck Pain trials

Study at a glance

From the registry record, last updated by the sponsor on 27 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Comparative Effects of an Eye-cervical Re-education and Motor Control Training Program on Pain, Range of Motion and Functional Disability in Chronic Neck Pain
ClinicalTrials.gov ID: NCT07438548
Acronym / sponsor ID: REC/RCR & AHS/24/01102
Conditions: Chronic Neck Pain
Keywords: Chronic Neck Pain, Neck Ache, Eye-cervical Re-education, Motor Control Training Program, Functional Disability
Study type: Interventional
Recruitment status: Completed
Enrolment: 52 participants (actual)
Lead sponsor: Riphah International UniversityUniversity, hospital or other
Study start: 13 Jan 2025 (actual)
Primary completion: 31 May 2025 (actual)
Study completion: 31 Oct 2025 (actual)
First posted: 27 Feb 2026 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

The study was conducted to determine the comparative effects of an eye-cervical re-education and motor control training program on pain, range of motion and functional disability in chronic neck pain

Study design

Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Single blind (outcomes assessor)
Number of arms: 2

Arm	Type	Receives
Eye-cervical Re-education Program	Experimental	Other: Eye-cervical Re-education Program, Other: Standardized Physiotherapy Treatment
Motor Control Training Program	Active comparator	Other: Motor Control Training Program, Other: Standardized Physiotherapy Treatment

Who may qualify

Ages: 18 to 50 years
Sex: All
Healthy volunteers: Not accepted
Age groups: Adult

Key inclusion criteria (5 listed)

Neck pain for minimum 3 months
Pain intensity on NPRS between 4 to 7
Limited neck range of motion
Medical diagnosis (Grade-II Neck pain) as per classification by "Bone and Joint Decade 2000-2010"
Cervical discomfort resulting from repetitive motion or prolonged postures.

Key exclusion criteria (4 listed)

History of neck trauma/Fracture/Surgery/ Whiplash Injury
Systemic illness, rheumatic conditions, inflammatory joint disease
Other spine pathologies Cervical myelopathy / Fibromyalgia / Multiple Sclerosis/ Cervical radiculopathy
Tumor symptoms like high temperature, shivering, night pain

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Eye-cervical Re-education ProgramEye-cervical Re-education program was carried out consisting of 10 proprioceptive reprogramming intervention steps : Activation of eye muscles, Passive cervical mobilization with fixed gaze, Active cervical mobility with directed gaze , Global cervical motion exercise , Neck mobility with the trunk , Head reposition exercise (Active), Head reposition exercise (Passive), Free coordination exercise, Manual resistance coordination exercise and Oculo-cervical coordination with soft stimuli. All exercises were done ten times each. 24 sessions were conducted for 8 weeks, with 3 sessions scheduled every week.	Other	Eye-cervical Re-education Program
Motor Control Training ProgramMotor Control Training Program was performed in supine position. It consisted of four parts, which include the cranio-cervical flexor exercise; co-contraction of neck flexors and extensors; the cranio-cervical extensor exercise; and the scapular re-education exercises. An air-filled cuff was put behind the neck and the patient tried to make five progressive positions with an increase in ROM i.e. to make improvements in pressure of 22, 24, 26, 28 and eventually 30 mmHg on pressure gauge. All exercises were done ten times each. 24 sessions were conducted for 8 weeks, with 3 sessions scheduled every week.	Other	Motor Control Training Program
Standardized Physiotherapy TreatmentElectric Hot pack and TENS having (200 µs pulse-width, 1Hz frequency) were applied for 10 minutes.	Other	Eye-cervical Re-education Program, Motor Control Training Program

Primary outcome

Numeric Pain Rating Scale
Time frame: From enrollment to the end of treatment at 8 weeks
Numeric Pain Rating Scale is a subjective measure using which patient's rate their pain. It consists of 11 points, having an overall score ranging from 0 to 10, where: 0, 1 - 3, 4 - 6, 7 - 10 represents no pain, mild, moderate and the most severe pain respectively
Neck Disability Index in Urdu language
Time frame: From enrollment to the end of treatment at 8 weeks
Neck pain disability index is used for the disability of the neck or the impact of neck pain on a person. It consists of 10 questions on pain intensity, personal care, lifting, reading, headaches, concentration, work, driving, sleeping and recreation. Performance in each item is described in 6 stages, from 0 to 5 points. The total of 0-4 points indicate no disability, 5-14 points indicate mild disability, 15-24 points indicate moderate disability, 25-34 points indicate severe disability and 35-50 points indicate complete disability
ROM Cervical spine (Flexion)
Time frame: From enrollment to the end of treatment at 8 weeks
Changes in cervical spine flexion ROM at baseline and 8th week of intervention was measured using goniometer.
ROM Cervical Spine (Extension)
Time frame: From enrollment to the end of treatment at 8 weeks
Changes in cervical spine extension ROM at baseline and 8th week of intervention was measured using goniometer.
ROM Cervical Spine (Lateral Flexion) Left Side
Time frame: From enrollment to the end of treatment at 8 weeks
Changes in cervical spine lateral flexion on left side ROM at baseline and 8th week of intervention was measured using goniometer.
ROM Cervical Spine (Lateral Flexion) Right Side
Time frame: From enrollment to the end of treatment at 8 weeks
Changes in cervical spine lateral flexion on right side ROM at baseline and 8th week of intervention was measured using goniometer.
ROM Cervical Spine (Rotation) Left Side
Time frame: From enrollment to the end of treatment at 8 weeks
Changes in cervical spine rotation on left side ROM at baseline and 8th week of intervention was measured using goniometer.
ROM Cervical Spine (Rotation) Right Side
Time frame: From enrollment to the end of treatment at 8 weeks
Changes in cervical spine rotation on right side ROM at baseline and 8th week of intervention was measured using goniometer.

Results and safety

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 27 Feb 2026.
BackgroundAgrawal M, Borkar P. Journal of Population Therapeutics & Clinical Pharmacology. 2010.
BackgroundAal NMA, Elkeblawy MA, Amine RAM. Effectiveness of eye-cervical re-education versus motor imagery therapy on chronic neck pain: A randomized controlled trial. Sport TK: revista euroamericana de ciencias del deporte. 2024(13):6.
BackgroundBhende R, Shinde S, Jain P. Effect of Integrated Postural Training in Individuals with TextNeck Syndrome. J Kinesiol Exerc Sci. 2024;108:1-18.
Background: PubMed 36598342Mendes Fernandes T, Mendez-Sanchez R, Puente-Gonzalez AS, Martin-Vallejo FJ, Falla D, Vila-Cha C. A randomized controlled trial on the effects of "Global Postural Re-education" versus neck specific exercise on pain, disability, postural control, and neuromuscular features in women with chronic non-specific neck pain. Eur J Phys Rehabil Med. 2023 Feb;59(1):42-53. doi: 10.23736/S1973-9087.22.07554-2. Epub 2023 Jan 4.
Background: PubMed 40420069Canli K, Demirkiran G, Can F. The efficiency of tactile discrimination training and oculomotor exercises in people with chronic neck pain: a randomized controlled trial. BMC Musculoskelet Disord. 2025 May 27;26(1):519. doi: 10.1186/s12891-025-08755-0.
Background: PubMed 38318308Goudarzi L, Ghomashchi H, Vahedi M, Kahlaee AH. Investigating the Effect of Addition of Cervical Proprioceptive Training to Conventional Physiotherapy on Visual, Vestibular and Proprioceptive Dependency of Postural Control in Patients with Chronic Non-Specific Neck Pain: A Randomized Controlled Clinical Trial. Arch Bone Jt Surg. 2024;12(1):36-50. doi: 10.22038/ABJS.2023.74763.3462.
Background: PubMed 35886255Majcen Rosker Z, Vodicar M, Kristjansson E. Relationship between Cervicocephalic Kinesthetic Sensibility Measured during Dynamic Unpredictable Head Movements and Eye Movement Control or Postural Balance in Neck Pain Patients. Int J Environ Res Public Health. 2022 Jul 9;19(14):8405. doi: 10.3390/ijerph19148405.
Background: PubMed 36941087Gumuscu BH, Kisa EP, Kara Kaya B, Muammer R. Comparison of three different exercise trainings in patients with chronic neck pain: a randomized controlled study. Korean J Pain. 2023 Apr 1;36(2):242-252. doi: 10.3344/kjp.22371. Epub 2023 Mar 21.
Background: PubMed 32184889Perez-Cabezas V, Ruiz-Molinero C, Jimenez-Rejano JJ, Chamorro-Moriana G, Gonzalez-Medina G, Chillon-Martinez R. Effectiveness of an Eye-Cervical Re-Education Program in Chronic Neck Pain: A Randomized Clinical Trial. Evid Based Complement Alternat Med. 2020 Feb 26;2020:2760413. doi: 10.1155/2020/2760413. eCollection 2020.
Background: PubMed 30881101Suvarnnato T, Puntumetakul R, Uthaikhup S, Boucaut R. Effect of specific deep cervical muscle exercises on functional disability, pain intensity, craniovertebral angle, and neck-muscle strength in chronic mechanical neck pain: a randomized controlled trial. J Pain Res. 2019 Mar 7;12:915-925. doi: 10.2147/JPR.S190125. eCollection 2019.
Individual participant dataSharing planned: No

Related trials for Chronic Neck Pain

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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Ali Raza, MS principal investigator

Riphah International University

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing Eye-cervical Re-education Program and Standardized Physiotherapy Treatment in people with Chronic Neck Pain, run by Riphah International University at 1 site in Pakistan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 27 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Numeric Pain Rating Scale (time frame: From enrollment to the end of treatment at 8 weeks). The study lists 8 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT07438548, which also lists 10 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Feb 2026.