Cigarette Smoking-Related CarcinomaNCT07439471
Understanding Tobacco and Cannabis Co-Use Practices: Initiation, Escalation, and Maintenance
An observational study of Cigarette Smoking-Related Carcinoma, run by Roswell Park Cancer Institute at 1 site in United States.
Trial summary
This study evaluates histories among cannabis and tobacco co-users of their initiation, escalation, and maintenance of the co-use behavior. Read more about this study
- Who is it for?
- Ages 18 to 30 years
- Conditions the study is for
- Cigarette Smoking-Related Carcinoma
- What is being tested?
- Non-Interventional Study
- How many people
- 40 participants
- Where
- 1 siteUnited States
- Study dates
- 28 Sep 2026to Mar 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- All sexes
- No healthy volunteers
- Adult
Study population: Adult cannabis users who also use cigarettes or nicotine vaping products.
Who may be able to join
- * Adults aged 18 to 30 years old.
- Currently living in the Roswell Park catchment area.
- Able to speak, read, and write in English.
- Currently consuming cannabis at least weekly.
- Group 1: currently using cigarettes daily and not using nicotine vaping products more than one day per week.
- Group 2: currently using nicotine vaping products daily and not using cigarettes more than one day per week.
Who cannot join
- * Unwilling or unable to follow protocol requirements.
- Individuals under the age of 18 or over 30.
- Individuals not meeting product consumption criteria for inclusion items 3 and 4.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Roswell Park Cancer Institute
Buffalo, New York, 14263
Connor Martin, 716-845-3295, Connor.Martin@roswellpark.org
Connor Martin
About this study
This study evaluates histories among cannabis and tobacco co-users of their initiation, escalation, and maintenance of the co-use behavior.
Read the detailed description
PRIMARY OBJECTIVE:
- To generate detailed thematic analysis of structured interviews to provide insights into individual historical factors, social contextual factors, and product-level factors that contribute to the co-use of nicotine/tobacco and cannabis products.
OUTLINE: This is an observational study.
Participants complete an interview and survey on study.
- Conditions
- Cigarette Smoking-Related Carcinoma
- Being tested
- Non-Interventional Study
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Non-Interventional StudyOther
Also called Non-Interventional Observational Study, Noninterventional (Observational) Study
Non-interventional study
| Study group | Role | What they receive |
|---|---|---|
| Observational | Participants complete an interview and survey on study. Receives: Other: Non-Interventional Study |
What is being measured
The primary outcome is the main question the study is designed to answer.
thematic analysis of individual narratives on nicotine and cannabis
Structured interview sessions
Measured: Reported at baseline
Secondary outcomes (3)
Insight into the Social contexts of use and co-use of nictotine and cannabis
Structured interview session on escalation of use
Measured: reported at baseline
Insight into Current practices of tobacco/cannabis use
Structured interview session on maintenance of use
Measured: reported at baseline
Insights into factors that contribute to the co-use of nicotine/tobacco and cannabis products
Structured interview sessions on history of use
Measured: reported at baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Feb 2026
- Study start28 Sep 2026 (estimated)
- Primary completionMar 2027 (estimated)
- Study completionMar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cigarette Smoking-Related CarcinomaStudies of the same condition, open and under way.
- More trials run by Roswell Park Cancer InstituteThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Roswell Park Cancer Institute
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Connor Martin, Principal investigator, Roswell Park Cancer Institute
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07439471
- Sponsor's protocol ID
- I-4794825
- Other IDs
- NCI-2026-00804, I-4794825
- Status last verified
- Aug 2026
- First submitted
- 12 Feb 2026
- Last updated
- 17 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Understanding Tobacco and Cannabis Co-Use Practices: Initiation, Escalation, and Maintenance
- ClinicalTrials.gov ID
- NCT07439471
- Acronym / sponsor ID
- I-4794825
- Conditions
- Cigarette Smoking-Related Carcinoma
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Roswell Park Cancer InstituteUniversity, hospital or other
- Study start
- 28 Sep 2026 (estimated)
- Primary completion
- Mar 2027 (estimated)
- Study completion
- Mar 2027 (estimated)
- First posted
- 27 Feb 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study evaluates histories among cannabis and tobacco co-users of their initiation, escalation, and maintenance of the co-use behavior.
Detailed description
PRIMARY OBJECTIVE:
- To generate detailed thematic analysis of structured interviews to provide insights into individual historical factors, social contextual factors, and product-level factors that contribute to the co-use of nicotine/tobacco and cannabis products.
OUTLINE: This is an observational study.
Participants complete an interview and survey on study.
Study design
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Observational | – | Other: Non-Interventional StudyParticipants complete an interview and survey on study. |
Who may qualify
- Ages
- 18 to 30 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
- Study population
- Adult cannabis users who also use cigarettes or nicotine vaping products.
Key inclusion criteria (6 listed)
- * Adults aged 18 to 30 years old.
Key exclusion criteria (3 listed)
- * Unwilling or unable to follow protocol requirements.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Non-Interventional StudyAlso: Non-Interventional Observational Study, Noninterventional (Observational) StudyNon-interventional study | Other | Observational |
Primary outcome
thematic analysis of individual narratives on nicotine and cannabis
Time frame: Reported at baseline
Structured interview sessions
3 secondary outcomes
Insight into the Social contexts of use and co-use of nictotine and cannabis
Time frame: reported at baseline
Insight into Current practices of tobacco/cannabis use
Time frame: reported at baseline
Insights into factors that contribute to the co-use of nicotine/tobacco and cannabis products
Time frame: reported at baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Aug 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Connor Martin principal investigator
Roswell Park Cancer Institute
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Cigarette Smoking-Related Carcinoma, run by Roswell Park Cancer Institute at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
thematic analysis of individual narratives on nicotine and cannabis (time frame: Reported at baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Aug 2026.