Clinical trials: Cigarette Smoking-Related Carcinoma
Cigarette Smoking-Related Carcinoma
PK/PD of Vaping THC-containing Liquids vs. Smoked Cannabis
We will conduct a randomized, within-subjects clinical study to compare short-term pharmacokinetic (PK) and pharmacodynamic (PD) effects of Δ9-tetrahydrocannabinol (THC) vaping liquids vs.
- Trial name
- NCT06055231
- Testing
- Vape device, Joint, Marijuana via vape device
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Cigarette Smoking-Related Carcinoma
Electronic Cigarette Use During Pregnancy
Aim 1: To compare the overall toxicant exposure in pregnant women who use electronic cigarettes (e-cigs, vapor, e-liquid, e-juice, vape, vaping devices) compared to women who smoke conventional cigarettes. Aim 2.
- Trial name
- NCT03480373
- Where
- 6 sites in United States
- Volunteers
- 182 people
- Sponsor
- UConn Health
Cigarette Smoking-Related Carcinoma
Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers
This phase II trial tests whether broccoli seed and sprout extract works to break down cancer causing substances of tobacco in heavy smokers. Smokers are at increased risk for developing lung, head and neck, and other cancers.
- Trial name
- NCT05121051
- Testing
- Biospecimen Collection, Broccoli Sprout/Broccoli Seed Extract Supplement, Questionnaire Administration
- Where
- 3 sites in United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Cigarette Smoking-Related Carcinoma
Impact of E-cigarette Use on the Body
This study examines how electronic (e)-cigarette use impacts the body, by studying both users and non-users of e-cigarettes. Early evidence indicates that e-cig users experience adverse health effects.
- Trial name
- NCT04972513
- Testing
- Biospecimen Collection, Nitric Oxide Breath Test, Oscillometry
- Where
- United States
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma
EQQUAL-NM for the Promotion of Smoking Cessation in Sexual and Gender Minority Young Adults in New Mexico
This clinical trial assesses the acceptability and efficacy of Empowered, Queer, Quitting, and Living--New Mexico (EQQUAL-NM), a smoking cessation intervention for sexual and gender minority young adults in New Mexico.
- Trial name
- NCT06386432
- Testing
- Smartphone App-delivered Smoking Cessation Intervention, Health Promotion and Education, Biospecimen Collection
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Cigarette Smoking-Related Carcinoma
Gender Differences in Switching From Smoking Regular Cigarettes to E-Cigarettes
This early phase I trial studies potential differences between men and women when switching from the use of combustible cigarettes to the National Institute on Drug Abuse's Standard Research E-Cigarette (SREC).
- Trial name
- NCT03856515
- Testing
- Nicotine Replacement, Questionnaire Administration, Electronic Cigarette
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Tobacco-Related Carcinoma
Nicotine and Tobacco Message Framing to Change Smoking Behavior in Diverse Groups of Young Adult Smokers
This clinical trial evaluates the effect of message framing on smoking behaviors among lesbian, gay, bisexual, transgender, queer (LGBTQ+) young adults who use nicotine and/or tobacco.
- Trial name
- NCT06644664
- Testing
- Health Education, Interview, Smoking Cessation Intervention
- Where
- United States
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma
Oral Nicotine Pouches Versus Nicotine Replacement Therapy to Reduce Cigarette Use for Smokers in Rural Appalachia
This clinical trial compares the use of oral nicotine pouches to nicotine replacement therapy, consisting of nicotine patches and lozenges, to reduce cigarette use in smokers living in rural Appalachia.
- Trial name
- ARISE (NCT06763536)
- Testing
- Carbon Monoxide Measurement, Nicotine Lozenge, Oral Nicotine Pouch
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma
Sensory Tests of Cigarettes for Identification of Flavors in Current Daily Smoking Adults
This clinical trial tests how well current daily smoking adults can identify flavors of cigarettes. Menthol cigarettes account for 31 percent of cigarettes sold in the United States.
- Trial name
- NCT06816459
- Testing
- Cigarette smell test, Cigarette Taste Test, Study questionnaires
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Cigarette Smoking-Related Carcinoma
Text Message and Mail Delivery of Tailored Educational Materials to Improve Access to Resources for Smoking Cessation of Menthol Tobacco Cigarettes
This clinical trial compares the impact of receiving educational materials containing relevant content about risks from smoking menthol cigarettes which include links to the New York (NY) Smoke-Free website by text message or…
- Trial name
- NCT07857681
- Testing
- Educational Intervention, Internet-Based Intervention, Smartphone Application-based Intervention
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Roswell Park Cancer Institute
Cigarette Smoking-Related Carcinoma
Appeal of Nicotine Pouches Versus Cigarettes in the Ohio Appalachia Population
This clinical trial estimates the abuse liability of nicotine pouches with varying nicotine concentrations relative to cigarette smoking in Appalachian, Ohio and Ohio smokers.
- Trial name
- NCT05236894
- Testing
- Cigarette Smoking, Nicotine Oral Pouch, Questionnaire Administration
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma
Smoking Cessation Intervention Development for Homeless Youth
This trial develops a contextually tailored and optimized smoking cessation intervention and studies smoking motivations and motivations to quit smoking in homeless youth.
- Trial name
- NCT06754215
- Testing
- Focus Group, Interview, Smoking Cessation Intervention
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma
Website Smoking Cessation Intervention for the Promotion of Smoking Cessation in Low-Income Veterans
This phase I trial studies how well a new electronic (e)-health smoking cessation program (called Vet Flexiquit) works in promoting smoking cessation in low-income veterans who may or may not be ready to quit smoking.
- Trial name
- NCT04502524
- Testing
- Smoking Cessation Intervention (New website), Smoking Cessation Intervention (Standard of care website), Health Education
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Cigarette Smoking-Related Carcinoma
Evaluating the Episodic Future Thinking Intervention for Reducing Cigarette Consumption in Cigarette Smokers
This clinical trial evaluates the effectiveness of active episodic future thinking (EFT) stimuli for reducing cigarette consumption in cigarette smokers.
- Trial name
- NCT05825001
- Testing
- Smoking Cessation Intervention, Smoking Cessation Intervention (control), Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Roswell Park Cancer Institute
Cigarette Smoking-Related Carcinoma
A Digital Smoking Cessation Intervention for Helping American Indians and Alaska Natives Quit Smoking, IndigeQuit Trial
This clinical trial compares a new smoking cessation smartphone application (app) (IndigeQuit) to an existing smarphone app (National Cancer Institute [NCI] QuitGuide) for helping American Indians and Alaska Natives (AI/ANs) quit…
- Trial name
- NCT06145763
- Testing
- Biospecimen Collection, Smoking Cessation Intervention, Survey Administration
- Where
- United States
- Volunteers
- 776 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Cigarette Smoking-Related Carcinoma
A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior
This clinical trial compares the use of tobacco flavored electronic cigarettes (ECs) vs. non-tobacco flavored ECs vs. nicotine replacement therapy (patches and lozenges) on smoking behavior in current cigarette smokers.
- Trial name
- NCT06260683
- Testing
- Nicotine Replacement, Questionnaire Administration, Vaping
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma
A Smartphone Application (QuitBot) for the Improvement of Smoking Cessation Among American Indians and Alaska Natives, NAITIVE Trial
This clinical trial develops a chatbot smartphone application (app), QuitBot, and text messaging to help American Indians (AI) and Alaska Natives (AN) to quit smoking commercial tobacco (smoking cessation), and evaluates two…
- Trial name
- NCT06697496
- Testing
- QuitBot Smoking Cessation Chatbot Program, QuitBot Smoking Cessation Text Messaging Program, Survey Administration
- Where
- United States
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Cigarette Smoking-Related Carcinoma
Avatar-Led Digital Therapeutic for Aiding Smoking Cessation in Sexual and Gender Minority Young Adults
This trial assesses the acceptability and preliminary efficacy of Empowered, Queer, Quitting, and Living (EQQUAL) smoking-cessation intervention for sexual and gender minority young adult smokers.
- Trial name
- NCT05847673
- Testing
- Online Smoking Cessation Intervention, Questionnaire Administration, Health Promotion and Education
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Cigarette Smoking-Related Carcinoma
Evaluating the Effect of Nicotine on Eye Movements and Related Behaviors in Electronic Cigarette Users, NICS-EYES Trial
This clinical trial evaluates the effect of nicotine on eye movements and related behaviors in people who use electronic (e)-cigarettes. Nicotine is an addictive, poisonous chemical found in tobacco.
- Trial name
- NCT07604246
- Testing
- Avoidance, Biospecimen Collection, Cigarette Smoking
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Cigarette Smoking-Related Carcinoma
Free-Base Nicotine or Nicotine Salt e-Liquids in Current E-Cigarette Smokers, PeloPET Study
This clinical trial studies the effect of free-base compared with nicotine salt based e-liquids on electronic cigarette (EC) puffing behavior, abuse liability, and deposition and absorption of nicotine in the respiratory tract…
- Trial name
- NCT05455086
- Testing
- Cigarette Smoking, Computed Tomography, Positron Emission Tomography
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Ohio State University Comprehensive Cancer Center