EpilepsyNCT07451093
Epileptiform Potential of Fully Immersive Virtual Reality
A study testing Virtual Reality Headset, display off and Virtual Reality Headset, Display only in people with Epilepsy and Seizure, run by Dartmouth-Hitchcock Medical Center at 1 site in United States.
Trial summary
The goal of this interventional study is to determine if the use of virtual reality headsets results in an increased risk of seizure in adolescent and adult individuals with epilepsy. Read more about this study
- Who is it for?
- Ages 13 years and older
- What is being tested?
- Virtual Reality Headset, display off and Virtual Reality Headset, Display only
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteUnited States
- Study dates
- Dec 2026to Jun 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 13 years and older
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Who may be able to join
- subjects with known or suspected diagnosis of epilepsy with interictal epileptiform discharges seen during current or prior EEG recording
- Age greater than or equal to 13 years
Who cannot join
- Age less than 13 years (infants, children)
- Pregnancy
- Incarceration
- Moderate-severe cognitive impairment
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, 03756
Jared E Quast, MD, 6033505104, jared.e.quast@hitchcock.org
Jared E Quast, MD
About this study
The goal of this interventional study is to determine if the use of virtual reality headsets results in an increased risk of seizure in adolescent and adult individuals with epilepsy. The main question it aims to answer are:
- does use of virtual reality headsets with hand controllers result in a higher risk of seizure compared to use of virtual reality headsets without hand controllers Participants will be asked to wear a virtual reality headset during continuous video EEG recording and EEG with be evaluated during three phases: with display turned off, with display turned on without hand controllers, and with display turned on with hand controllers.
- Being tested
- Virtual Reality Headset, display off, Virtual Reality Headset, Display only, Virtual Reality Headset, Display and Hand Control
- Keywords
- Epilepsy, Seizure, Virtual Reality, VR, Reflex epilepsy
- Medical subject headings
- Epilepsy, Seizures, Epilepsy, Reflex
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Virtual Reality Headset, display offOther
15 minutes of EEG recording with VR headset worn, display turned off. This will act as a baseline for intervention 2 and 3
Virtual Reality Headset, Display onlyOther
15 minutes of EEG recording with VR headset worn, display turned on without access to hand controls.
Virtual Reality Headset, Display and Hand ControlOther
15 minutes of EEG recording with VR headset worn, display turned on with access to hand controls
| Study group | Role | What they receive |
|---|---|---|
| Virtual Reality Arm | Experimental | Participants wear VR headset during video EEG recording for a total of 3 sessions, each lasting 15 minutes each. Receives: Other: Virtual Reality Headset, display off; Other: Virtual Reality Headset, Display only; Other: Virtual Reality Headset, Display and Hand Control |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in prevalence of interictal epileptiform discharges
Interictal epileptiform discharges are counted by two epilepsy trained neurologists. Number of discharges seen are compared between each intervention.
Measured: Three sessions, 15 minutes each
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 Mar 2026
- Study startDec 2026 (estimated)
- Primary completionJun 2027 (estimated)
- Study completionJun 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for EpilepsyStudies of the same condition, open and under way.
- More trials run by Dartmouth-Hitchcock Medical CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Jared.E.Quast, Dartmouth-Hitchcock Medical Center
- Investigators
- Jared E Quast, MD, Principal investigator, Dartmouth-Hitchcock Medical Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07451093
- Sponsor's protocol ID
- 02002874
- Status last verified
- Apr 2026
- First submitted
- 12 Feb 2026
- Last updated
- 27 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 27 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Epileptiform Potential of Fully Immersive Virtual Reality
- ClinicalTrials.gov ID
- NCT07451093
- Acronym / sponsor ID
- 02002874
- Keywords
- Epilepsy, Seizure, Virtual Reality, VR, Reflex epilepsy
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Dartmouth-Hitchcock Medical CenterUniversity, hospital or other
- Study start
- Dec 2026 (estimated)
- Primary completion
- Jun 2027 (estimated)
- Study completion
- Jun 2027 (estimated)
- First posted
- 5 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this interventional study is to determine if the use of virtual reality headsets results in an increased risk of seizure in adolescent and adult individuals with epilepsy. The main question it aims to answer are:
- does use of virtual reality headsets with hand controllers result in a higher risk of seizure compared to use of virtual reality headsets without hand controllers Participants will be asked to wear a virtual reality headset during continuous video EEG recording and EEG with be evaluated during three phases: with display turned off, with display turned on without hand controllers, and with display turned on with hand controllers.
Study design
- Primary purpose
- Supportive care
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Virtual Reality Arm | Experimental | Other: Virtual Reality Headset, display off, Other: Virtual Reality Headset, Display only, Other: Virtual Reality Headset, Display and Hand ControlParticipants wear VR headset during video EEG recording for a total of 3 sessions, each lasting 15 minutes each. |
Who may qualify
- Ages
- 13 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (2 listed)
- subjects with known or suspected diagnosis of epilepsy with interictal epileptiform discharges seen during current or prior EEG recording
- Age greater than or equal to 13 years
Key exclusion criteria (4 listed)
- Age less than 13 years (infants, children)
- Pregnancy
- Incarceration
- Moderate-severe cognitive impairment
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Virtual Reality Headset, display off15 minutes of EEG recording with VR headset worn, display turned off. This will act as a baseline for intervention 2 and 3 | Other | Virtual Reality Arm |
| Virtual Reality Headset, Display only15 minutes of EEG recording with VR headset worn, display turned on without access to hand controls. | Other | Virtual Reality Arm |
| Virtual Reality Headset, Display and Hand Control15 minutes of EEG recording with VR headset worn, display turned on with access to hand controls | Other | Virtual Reality Arm |
Primary outcome
Change in prevalence of interictal epileptiform discharges
Time frame: Three sessions, 15 minutes each
Interictal epileptiform discharges are counted by two epilepsy trained neurologists. Number of discharges seen are compared between each intervention.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Aug 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Jared E Quast, MD principal investigator
Dartmouth-Hitchcock Medical Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Virtual Reality Headset, display off and Virtual Reality Headset, Display only in people with Epilepsy and Seizure, run by Dartmouth-Hitchcock Medical Center at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 27 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Jared E Quast, MD (6033505104, jared.e.quast@hitchcock.org), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in prevalence of interictal epileptiform discharges (time frame: Three sessions, 15 minutes each). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Aug 2026; AzTrials last refreshed its copy on 1 Nov 2026.