Nursing EducationVR-CBS-ECGNCT07468942
Virtual Reality Versus Computer-Based Simulation in Electrocardiogram Education
A study testing Immersive Virtual Reality Simulation, Computer-Based Simulation and Traditional Laboratory Practice in people with Nursing Education, run by Koç University at 1 site in Turkey (Türkiye).
Trial summary
The goal of this clinical trial is to compare the effects of immersive virtual reality (VR) simulation and computer-based simulation (CBS) with traditional laboratory practice on electrocardiogram (ECG) knowledge, practical skills, and motivation in first-year undergraduate nursing students. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Nursing Education
- What is being tested?
- Immersive Virtual Reality Simulation, Computer-Based Simulation and Traditional Laboratory Practice
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 90 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Sep 2022to 1 Feb 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- First-year undergraduate nursing student enrollment
- Voluntary participation
- No prior ECG simulation training experience
- No visual impairment
Who cannot join
- Prior ECG simulation training experience
- Visual impairment
- Unwillingness to participate
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Virtual Reality Versus Computer-Based Simulation in Electrocardiogram Education: Effects on Nursing Students' Knowledge, Skills, and Motivation: A Randomized Controlled Trial
The goal of this clinical trial is to compare the effects of immersive virtual reality (VR) simulation and computer-based simulation (CBS) with traditional laboratory practice on electrocardiogram (ECG) knowledge, practical skills, and motivation in first-year undergraduate nursing students. The main questions it aims to answer are:
Does VR simulation improve ECG knowledge scores more than CBS and traditional laboratory practice? Does VR simulation improve ECG practical skill scores more than CBS and traditional laboratory practice? Does VR simulation improve learner motivation more than CBS and traditional laboratory practice?
Read more
Researchers will compare three groups - VR simulation, computer-based simulation, and traditional laboratory practice - to see which method is most effective for ECG education outcomes.
Participants will:
Attend a standardized 90-minute ECG lecture before the intervention Be randomly assigned to one of three groups: VR simulation, computer-based simulation, or traditional laboratory practice Complete a 90-minute educational intervention according to their assigned group Complete knowledge, skills, and motivation assessments before and one week after the intervention
Read the detailed description
This three-arm randomized controlled trial was conducted at Beykent University, Istanbul, Turkey. The study population consisted of first-year undergraduate nursing students. Inclusion criteria were: voluntary participation, first-year enrollment, no prior ECG simulation training, and no visual impairment.
Sample size was calculated using G*Power 3.1.9.4 based on a medium effect size (f=0.40), α=0.05, and 80% power, yielding a minimum of 66 participants (22 per group). To account for potential attrition, 90 students were enrolled and randomly allocated to three groups: immersive virtual reality (VR) simulation (n=30), computer-based simulation (CBS) (n=30), and traditional laboratory practice (n=30).
All participants completed baseline assessments and attended a standardized 90-minute ECG lecture delivered by the same instructor. One week later, participants were randomly assigned to their intervention groups. The VR group performed three-dimensional ECG scenarios using Oculus Quest 2 (128GB) all-in-one headsets with integrated touch controllers, enabling full immersion and hand-tracking interactions simulating real ECG procedural movements. The CBS group completed interactive ECG modules developed with technical support from computer engineering specialists, covering ECG physiology, rhythm recognition scenarios, and nursing care protocols. The control group practiced on manikins with verbal instruction. All interventions lasted 90 minutes. Post-intervention assessments were conducted one week after the intervention.
Outcomes were assessed using three instruments. The ECG Knowledge Test is a researcher-developed multiple-choice test measuring ECG physiology, rhythm recognition, and interpretation, with content validity established by six medical-surgical nursing faculty. The ECG Skills Checklist is a researcher-developed checklist covering patient preparation, electrode placement, device operation, and strip interpretation, validated by five faculty experts; steps were scored as unsuccessful (0), requires improvement (2.5), or successful (5 points). The Instructional Materials Motivation Survey (IMMS) is a 33-item, 5-point Likert scale based on the ARCS model (Attention, Relevance, Confidence, Satisfaction), adapted to Turkish by Dinçer and Doğanay (2016); total scores range from 33 to 165, with higher scores indicating greater motivation. Cronbach's alpha in this study was 0.956.
Random allocation was conducted by an independent researcher not involved in data collection or intervention delivery, using a computer-generated random number sequence via www.random.org. Allocation concealment was maintained through sealed, sequentially numbered envelopes opened only after baseline assessments were recorded. Due to the nature of educational simulation interventions, blinding of participants and instructors was not feasible; however, the researcher responsible for baseline data collection was blinded to the randomization sequence before allocation.
Data were analyzed using IBM SPSS (v22.0). Normality was assessed via skewness, kurtosis, and the Shapiro-Wilk test. Between-group differences were examined using one-way ANOVA with post hoc Tukey tests. Within-group changes were assessed using repeated-measures ANOVA. ANCOVA was conducted with age and sex as covariates to account for baseline demographic imbalances. Partial eta-squared (η²) was used to index effect size. Significance was set at p<0.05.
- Conditions
- Nursing Education
- Being tested
- Immersive Virtual Reality Simulation, Computer-Based Simulation, Traditional Laboratory Practice
- Keywords
- Electrocardiogram, Nursing students, virtual reality, nursing education, simulation, Computer-Based Simulation
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Immersive Virtual Reality SimulationBehavioural
Participants wore an Oculus Quest 2 (128GB) all-in-one VR headset with integrated touch controllers for a 90-minute session. Unlike screen-based approaches, this intervention provided full sensory immersion and hand-tracking interactions, enabling participants to physically simulate ECG procedures - including patient preparation, electrode placement, device operation, and rhythm strip interpretation - within a three-dimensional virtual clinical environment. The embodied, sensorimotor engagement distinguishes this intervention from both computer-based and traditional modalities.
Computer-Based SimulationBehavioural
ECG training program on standard computer screens. The program was developed by the research team with technical support from computer engineering specialists and covered ECG physiology modules, rhythm recognition scenarios, and nursing care protocols. Content validity was established by three medical-surgical nursing faculty. Unlike immersive VR, this intervention provides visual interactivity without kinesthetic or sensorimotor engagement. Unlike traditional practice, it offers structured digital feedback and repeated scenario exposure.
Traditional Laboratory PracticeBehavioural
manikin-based ECG skills session with verbal instruction delivered by the same instructor across all control group participants, following the standard nursing skills laboratory curriculum. This intervention represents the conventional teaching approach without digital simulation, interactive feedback loops, or immersive technology, serving as the active control condition.
| Study group | Role | What they receive |
|---|---|---|
| Virtual Reality Simulation | Experimental | Participants used an Oculus Quest 2 all-in-one headset with integrated touch controllers to perform three-dimensional ECG scenarios in an immersive virtual environment. The intervention simulated real ECG procedural movements, including patient preparation, electrode placement, and device operation. Receives: Behavioral: Immersive Virtual Reality Simulation |
| Computer-Based Simulation | Experimental | Participants completed interactive ECG training modules on computer screens. The program covered ECG physiology, rhythm recognition scenarios, and nursing care protocols, developed with technical support from computer engineering specialists and validated by three medical-surgical nursing faculty. Receives: Behavioral: Computer-Based Simulation |
| Traditional Laboratory Practice | Other | Participants practiced ECG skills on manikins with verbal instruction from the same instructor, following the standard laboratory curriculum. Receives: Behavioral: Traditional Laboratory Practice |
What is being measured
The primary outcome is the main question the study is designed to answer.
ECG Knowledge Score
Measured using a researcher-developed multiple-choice ECG Knowledge Test covering ECG physiology, rhythm recognition, and interpretation. Scores range from 0 to 100, with higher scores indicating greater knowledge.
Measured: two week after intervention
Secondary outcomes (1)
ECG Practical Skill Score
Measured using a researcher-developed ECG Skills Checklist covering patient preparation, electrode placement, device operation, and strip interpretation. Steps scored as unsuccessful (0), requires improvement (2.5), or successful (5 points).
Measured: Two week after intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Mar 2026
- Study start1 Sep 2022
- Primary completion1 Dec 2022
- Study completion1 Feb 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Nursing EducationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Three parallel arms with no crossover: VR simulation, computer-based simulation, and traditional laboratory practice.
- Masking
- None (open label)
- Enrolment
- 90 participants (actual)
Sponsor and investigators
- Lead sponsor
- Koç University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Meryem Ayvaz, Koç University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07468942
- Sponsor's protocol ID
- E-10420511-050-15749
- Acronym
- VR-CBS-ECG
- Status last verified
- Mar 2026
- First submitted
- 9 Mar 2026
- Last updated
- 16 Mar 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 16 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Virtual Reality Versus Computer-Based Simulation in Electrocardiogram Education: Effects on Nursing Students' Knowledge, Skills, and Motivation: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07468942
- Acronym / sponsor ID
- VR-CBS-ECG / E-10420511-050-15749
- Conditions
- Nursing Education
- Keywords
- Electrocardiogram, Nursing students, virtual reality, nursing education, simulation, Computer-Based Simulation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 90 participants (actual)
- Lead sponsor
- Koç UniversityUniversity, hospital or other
- Study start
- 1 Sep 2022 (actual)
- Primary completion
- 1 Dec 2022 (actual)
- Study completion
- 1 Feb 2023 (actual)
- First posted
- 13 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to compare the effects of immersive virtual reality (VR) simulation and computer-based simulation (CBS) with traditional laboratory practice on electrocardiogram (ECG) knowledge, practical skills, and motivation in first-year undergraduate nursing students. The main questions it aims to answer are:
Does VR simulation improve ECG knowledge scores more than CBS and traditional laboratory practice? Does VR simulation improve ECG practical skill scores more than CBS and traditional laboratory practice? Does VR simulation improve learner motivation more than CBS and traditional laboratory practice?
Researchers will compare three groups - VR simulation, computer-based simulation, and traditional laboratory practice - to see which method is most effective for ECG education outcomes.
Participants will:
Attend a standardized 90-minute ECG lecture before the intervention Be randomly assigned to one of three groups: VR simulation, computer-based simulation, or traditional laboratory practice Complete a 90-minute educational intervention according to their assigned group Complete knowledge, skills, and motivation assessments before and one week after the intervention
Detailed description
This three-arm randomized controlled trial was conducted at Beykent University, Istanbul, Turkey. The study population consisted of first-year undergraduate nursing students. Inclusion criteria were: voluntary participation, first-year enrollment, no prior ECG simulation training, and no visual impairment.
Sample size was calculated using G*Power 3.1.9.4 based on a medium effect size (f=0.40), α=0.05, and 80% power, yielding a minimum of 66 participants (22 per group). To account for potential attrition, 90 students were enrolled and randomly allocated to three groups: immersive virtual reality (VR) simulation (n=30), computer-based simulation (CBS) (n=30), and traditional laboratory practice (n=30).
All participants completed baseline assessments and attended a standardized 90-minute ECG lecture delivered by the same instructor. One week later, participants were randomly assigned to their intervention groups. The VR group performed three-dimensional ECG scenarios using Oculus Quest 2 (128GB) all-in-one headsets with integrated touch controllers, enabling full immersion and hand-tracking interactions simulating real ECG procedural movements. The CBS group completed interactive ECG modules developed with technical support from computer engineering specialists, covering ECG physiology, rhythm recognition scenarios, and nursing care protocols. The control group practiced on manikins with verbal instruction. All interventions lasted 90 minutes. Post-intervention assessments were conducted one week after the intervention.
Outcomes were assessed using three instruments. The ECG Knowledge Test is a researcher-developed multiple-choice test measuring ECG physiology, rhythm recognition, and interpretation, with content validity established by six medical-surgical nursing faculty. The ECG Skills Checklist is a researcher-developed checklist covering patient preparation, electrode placement, device operation, and strip interpretation, validated by five faculty experts; steps were scored as unsuccessful (0), requires improvement (2.5), or successful (5 points). The Instructional Materials Motivation Survey (IMMS) is a 33-item, 5-point Likert scale based on the ARCS model (Attention, Relevance, Confidence, Satisfaction), adapted to Turkish by Dinçer and Doğanay (2016); total scores range from 33 to 165, with higher scores indicating greater motivation. Cronbach's alpha in this study was 0.956.
Random allocation was conducted by an independent researcher not involved in data collection or intervention delivery, using a computer-generated random number sequence via www.random.org. Allocation concealment was maintained through sealed, sequentially numbered envelopes opened only after baseline assessments were recorded. Due to the nature of educational simulation interventions, blinding of participants and instructors was not feasible; however, the researcher responsible for baseline data collection was blinded to the randomization sequence before allocation.
Data were analyzed using IBM SPSS (v22.0). Normality was assessed via skewness, kurtosis, and the Shapiro-Wilk test. Between-group differences were examined using one-way ANOVA with post hoc Tukey tests. Within-group changes were assessed using repeated-measures ANOVA. ANCOVA was conducted with age and sex as covariates to account for baseline demographic imbalances. Partial eta-squared (η²) was used to index effect size. Significance was set at p<0.05.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
- Model description
- Three parallel arms with no crossover: VR simulation, computer-based simulation, and traditional laboratory practice.
| Arm | Type | Receives |
|---|---|---|
| Virtual Reality Simulation | Experimental | Behavioral: Immersive Virtual Reality SimulationParticipants used an Oculus Quest 2 all-in-one headset with integrated touch controllers to perform three-dimensional ECG scenarios in an immersive virtual environment. The intervention simulated real ECG procedural movements, including patient preparation, electrode placement, and device operation. |
| Computer-Based Simulation | Experimental | Behavioral: Computer-Based SimulationParticipants completed interactive ECG training modules on computer screens. The program covered ECG physiology, rhythm recognition scenarios, and nursing care protocols, developed with technical support from computer engineering specialists and validated by three medical-surgical nursing faculty. |
| Traditional Laboratory Practice | Other | Behavioral: Traditional Laboratory PracticeParticipants practiced ECG skills on manikins with verbal instruction from the same instructor, following the standard laboratory curriculum. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- First-year undergraduate nursing student enrollment
- Voluntary participation
- No prior ECG simulation training experience
- No visual impairment
Key exclusion criteria (3 listed)
- Prior ECG simulation training experience
- Visual impairment
- Unwillingness to participate
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Immersive Virtual Reality SimulationParticipants wore an Oculus Quest 2 (128GB) all-in-one VR headset with integrated touch controllers for a 90-minute session. Unlike screen-based approaches, this intervention provided full sensory immersion and hand-tracking interactions, enabling participants to physically simulate ECG procedures - including patient preparation, electrode placement, device operation, and rhythm strip interpretation - within a three-dimensional virtual clinical environment. The embodied, sensorimotor engagement distinguishes this intervention from both computer-based and traditional modalities. | Behavioural | Virtual Reality Simulation |
| Computer-Based SimulationECG training program on standard computer screens. The program was developed by the research team with technical support from computer engineering specialists and covered ECG physiology modules, rhythm recognition scenarios, and nursing care protocols. Content validity was established by three medical-surgical nursing faculty. Unlike immersive VR, this intervention provides visual interactivity without kinesthetic or sensorimotor engagement. Unlike traditional practice, it offers structured digital feedback and repeated scenario exposure. | Behavioural | Computer-Based Simulation |
| Traditional Laboratory Practicemanikin-based ECG skills session with verbal instruction delivered by the same instructor across all control group participants, following the standard nursing skills laboratory curriculum. This intervention represents the conventional teaching approach without digital simulation, interactive feedback loops, or immersive technology, serving as the active control condition. | Behavioural | Traditional Laboratory Practice |
Primary outcome
ECG Knowledge Score
Time frame: two week after intervention
Measured using a researcher-developed multiple-choice ECG Knowledge Test covering ECG physiology, rhythm recognition, and interpretation. Scores range from 0 to 100, with higher scores indicating greater knowledge.
1 secondary outcome
ECG Practical Skill Score
Time frame: Two week after intervention
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Mar 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Immersive Virtual Reality Simulation, Computer-Based Simulation and Traditional Laboratory Practice in people with Nursing Education, run by Koç University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
ECG Knowledge Score (time frame: two week after intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Mar 2026.