Knee OsteoarthritisNCT07482410
Combined Effects of Feldenkrais Exercises and Active Release Exercises in Patients With Knee Osteoarthritis.
A study testing Active release and feldenkrais exercises along with standard physical therapy. in people with Knee Osteoarthritis and Disability, run by Riphah International University at 1 site in Pakistan.
Trial summary
Knee osteoarthritis is similarly to the arthritis of the hip which is due to the degeneration of the cartilagre due to wear and tear forces on the knee joint. The aim of the study is to investigate the combined effects of active release and feldenkrais exercises on pain, range of motion and functional disability of… Read more about this study
- Who is it for?
- Ages 40 to 60 years
- Conditions the study is for
- Knee Osteoarthritis, Disability, Pain
- What is being tested?
- Active release and feldenkrais exercises along with standard physical therapy.
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 sitePakistan
- Study dates
- 15 Feb 2025to 15 Mar 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Both genders with age between 40-60 with knee osteoarthritis.
- BMI 25-29.9
- Knee pain 3-7 on NPRS
- 10-degree decrease in knee flexion range
Who cannot join
- Patient who used any corticosteroid injection during last six months.
- Patients who had any joint infection.
- Previous knee surgery.
- Grade 4/ advanced knee osteoarthritis
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Combined Effects of Feldenkrais Exercises and Active Release Exercises on Pain, Range of Motion and Functional Disability in Patients With Knee Osteoarthritis
Knee osteoarthritis is similarly to the arthritis of the hip which is due to the degeneration of the cartilagre due to wear and tear forces on the knee joint. The aim of the study is to investigate the combined effects of active release and feldenkrais exercises on pain, range of motion and functional disability of patients with knee osteoarthritis.
Read the detailed description
The study will be randomized control trial and will be conducted in associated hospitals of Riphah International University and physiotherapy department of Naseer Hospital. Non-probability consecutive sampling technique will be used. Sample size of age group 40 to 65 will be selected. Patients will be assigned into two group named experimental group and control group respectively. Experimental group will receive active release technique and feldenkrais exercises along with standard physical therapy protocol including mulligan mobilization. On the other hand, control group will receive standard physical therapy protocol including mulligan mobilization alone. Outcomes of pain will be measured by using Numeric Pain Rating Scale (NPRS), Range of Motion will be measured by using Universal Goniometer (UG) and Functional disability will be measured by using Western Ontario and McMaster Universities of Arthritis (WOMAC) Osteoarthritis Index. Informed consent will be taken. Subjects will be selected on the basis of inclusion and exclusion criteria and will be randomly divide into two groups experimental and control group respectively. Data analysis will be done by using SPSS version 28.
- Conditions
- Knee Osteoarthritis, Disability, Pain, Range of Motion
- Being tested
- Active release and feldenkrais exercises along with standard physical therapy.
- Keywords
- Knee Osteoarthritis, Active release technique, Feldenkrais exercise, disability, Pain, range of motion
- Medical subject headings
- Osteoarthritis, Knee, Pain
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Active release and feldenkrais exercises along with standard physical therapy.Other
Patients will receive active release and feldenkrais exercises for 3 sessions per week for the total of 6 weeks each exercise 10 repetitions and 2 sets.
| Study group | Role | What they receive |
|---|---|---|
| Active release and feldenkrais exercises along with standard physical therapy. | Active comparator | Patients will receive active release and feldenkrais exercises along with standard physical therapy treatment.
Standardized Physiotherapy treatment:
* Hot pack for 10 minutes and
* TENS for 10 minutes
* Hamstring stretching
* Quadriceps strengthening
* Squat release exercises Receives: Other: Active release and feldenkrais exercises along with standard physical therapy. |
| Active release exercises and standard physical therapy treatment. | Other | Patients will receive active release exercises and standard physical therapy treatment.
Standardized Physiotherapy treatment:
* Hot pack for 10 minutes and
* TENS for 10 minutes
* Hamstring stretching
* Quadriceps strengthening
* Squat release exercises Receives: Other: Active release and feldenkrais exercises along with standard physical therapy. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Numerical Pain Rating Scale (NPRS)
Patient level of pain will be assessed using this scale. This scale ranges from 0 to 10. 0 indicates "no pain" and 10 indicates "worst pain". NPRS have shown high test-retest reliability (r = 0.96 and 0.95, respectively).
Measured: 8 weeks
Universal Goniometer (UG)
The range of motion will be measured using universal goniometer that has an inter-rater reliability (ICC2, 2 = 0.79 to 0.92) for knee osteoarthritis.
Measured: 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Mar 2026
- Study start15 Feb 2025
- Primary completion15 Mar 2026 (estimated)
- Study completion15 Mar 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Knee OsteoarthritisStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants received active release technique and feldenkrais exercises along with standard physical therapy and mulligan mobilization.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Faiza Taufiq, MSPT, Principal investigator, Riphah International UniversityFaiza Taufiq, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07482410
- Sponsor's protocol ID
- S24C14G30036
- Status last verified
- Mar 2026
- First submitted
- 23 Feb 2026
- Last updated
- 19 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 19 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Combined Effects of Feldenkrais Exercises and Active Release Exercises on Pain, Range of Motion and Functional Disability in Patients With Knee Osteoarthritis
- ClinicalTrials.gov ID
- NCT07482410
- Acronym / sponsor ID
- S24C14G30036
- Conditions
- Knee Osteoarthritis, Disability, Pain, Range of Motion
- Keywords
- Knee Osteoarthritis, Active release technique, Feldenkrais exercise, disability, Pain, range of motion
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 15 Feb 2025 (actual)
- Primary completion
- 15 Mar 2026 (estimated)
- Study completion
- 15 Mar 2026 (estimated)
- First posted
- 19 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Knee osteoarthritis is similarly to the arthritis of the hip which is due to the degeneration of the cartilagre due to wear and tear forces on the knee joint. The aim of the study is to investigate the combined effects of active release and feldenkrais exercises on pain, range of motion and functional disability of patients with knee osteoarthritis.
Detailed description
The study will be randomized control trial and will be conducted in associated hospitals of Riphah International University and physiotherapy department of Naseer Hospital. Non-probability consecutive sampling technique will be used. Sample size of age group 40 to 65 will be selected. Patients will be assigned into two group named experimental group and control group respectively. Experimental group will receive active release technique and feldenkrais exercises along with standard physical therapy protocol including mulligan mobilization. On the other hand, control group will receive standard physical therapy protocol including mulligan mobilization alone. Outcomes of pain will be measured by using Numeric Pain Rating Scale (NPRS), Range of Motion will be measured by using Universal Goniometer (UG) and Functional disability will be measured by using Western Ontario and McMaster Universities of Arthritis (WOMAC) Osteoarthritis Index. Informed consent will be taken. Subjects will be selected on the basis of inclusion and exclusion criteria and will be randomly divide into two groups experimental and control group respectively. Data analysis will be done by using SPSS version 28.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- Participants received active release technique and feldenkrais exercises along with standard physical therapy and mulligan mobilization.
| Arm | Type | Receives |
|---|---|---|
| Active release and feldenkrais exercises along with standard physical therapy. | Active comparator | Other: Active release and feldenkrais exercises along with standard physical therapy.Patients will receive active release and feldenkrais exercises along with standard physical therapy treatment. Standardized Physiotherapy treatment: * Hot pack for 10 minutes and * TENS for 10 minutes * Hamstring stretching * Quadriceps strengthening * Squat release exercises |
| Active release exercises and standard physical therapy treatment. | Other | Other: Active release and feldenkrais exercises along with standard physical therapy.Patients will receive active release exercises and standard physical therapy treatment. Standardized Physiotherapy treatment: * Hot pack for 10 minutes and * TENS for 10 minutes * Hamstring stretching * Quadriceps strengthening * Squat release exercises |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- Both genders with age between 40-60 with knee osteoarthritis.
- BMI 25-29.9
- Knee pain 3-7 on NPRS
- 10-degree decrease in knee flexion range
Key exclusion criteria (4 listed)
- Patient who used any corticosteroid injection during last six months.
- Patients who had any joint infection.
- Previous knee surgery.
- Grade 4/ advanced knee osteoarthritis
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Active release and feldenkrais exercises along with standard physical therapy.Patients will receive active release and feldenkrais exercises for 3 sessions per week for the total of 6 weeks each exercise 10 repetitions and 2 sets. | Other | Active release and feldenkrais exercises along with standard physical therapy., Active release exercises and standard physical therapy treatment. |
Primary outcome
Numerical Pain Rating Scale (NPRS)
Time frame: 8 weeks
Patient level of pain will be assessed using this scale. This scale ranges from 0 to 10. 0 indicates "no pain" and 10 indicates "worst pain". NPRS have shown high test-retest reliability (r = 0.96 and 0.95, respectively).
Universal Goniometer (UG)
Time frame: 8 weeks
The range of motion will be measured using universal goniometer that has an inter-rater reliability (ICC2, 2 = 0.79 to 0.92) for knee osteoarthritis.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Mar 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Faiza Taufiq, MSPT principal investigator
Riphah International University
Faiza Taufiq principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Active release and feldenkrais exercises along with standard physical therapy. in people with Knee Osteoarthritis and Disability, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 19 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Numerical Pain Rating Scale (NPRS) (time frame: 8 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Mar 2026.