Parkinson's Disease (PD)NCT07484451
Effects Of Strategy Training And PNF On Balance, Gait, And Independence In Parkinson's Disease
A study testing PNF Technique and Strategy Training in people with Parkinson's Disease (PD), run by Riphah International University at 2 sites in Pakistan.
Trial summary
This randomized controlled trial aims to compare the effects of Strategy Training and Proprioceptive Neuromuscular Facilitation (PNF) on balance, gait, and functional independence in patients with Parkinson's disease. Parkinson's disease leads to impaired motor function, reduced balance, and decreased independence. Read more about this study
- Who is it for?
- Ages 40 to 80 years
- Conditions the study is for
- Parkinson's Disease (PD)
- What is being tested?
- PNF Technique and Strategy Training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 42 participants
- Where
- 2 sitesPakistan
- Study dates
- Mar 2026to May 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Inclusion Criteria:Diagnosed with Parkinson's Disease. Aged 40 to 80 years UPDRS level should be 2 and score will be 20-60 Able to walk independently or with minimal assistance Cognitively able to follow instructions
Exclusion Criteria:Severe comorbidities (e.g., cardiovascular, neurological) Recent surgery (within the last 6 months) Recent changes in Parkinson's medication Currently participating in other clinical trials Uncontrolled symptoms of Parkinson's Disease (e.g., severe tremors) Contraindications to rehabilitation treatment Resting systolic blood pressure>160mmHgor<100mmHg and resting diastolic pressure>100mmHg<6mmHg
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Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan2 sites
Global hospital and dialysis center Lahore
Lahore, Punjab Province, 54000
Hafiza Amna Adil, MSPT-NM, +923281324377, amnaadil406pap@gmail.com
Majid medical complex Lahore
Lahore, Punjab Province, 54000
Hafiza Amna Adil, +923281324377, amnaadil406pap@gmail.com
About this study
Official title: Effects of Strategy Training Versus Proprioceptive Neuromuscular Facilitation Technique on Balance, Gait, and Functional Independence in Patients With Parkinson's Disease
This randomized controlled trial aims to compare the effects of Strategy Training and Proprioceptive Neuromuscular Facilitation (PNF) on balance, gait, and functional independence in patients with Parkinson's disease. Parkinson's disease leads to impaired motor function, reduced balance, and decreased independence. Physiotherapy interventions such as strategy-based training and PNF may help improve mobility and functional performance. Participants will be randomly assigned to two groups: one receiving Strategy Training and the other receiving PNF intervention. Outcome measures including balance tests, gait assessment, and functional independence scales will be evaluated before and after treatment. The study aims to determine which intervention is more effective in improving functional outcomes in Parkinson's disease patients.
- Conditions
- Parkinson's Disease (PD)
- Being tested
- PNF Technique, Strategy Training
- Keywords
- Parkinson's disease, PNF, strategy-based training, ADLs
- Medical subject headings
- Parkinson Disease
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
PNF TechniqueOther
Participants will undergo PNF techniques targeting the muscles involved in balance and gait. This may include diagonal patterns, facilitation techniques, and proprioceptive neuromuscular facilitation holds.
Strategy TrainingOther
Strategy Training Group Participants will receive training in specific cognitive strategies to improve balance and gait. This will include visual cues, verbal instructions, and mental rehearsal techniques.
| Study group | Role | What they receive |
|---|---|---|
| Group A: PNF Technique | Experimental | Participants will undergo PNF techniques targeting the muscles involved in balance and gait. This may include diagonal patterns, facilitation techniques, and proprioceptive neuromuscular facilitation holds. Receives: Other: PNF Technique |
| Group B: Strategy training | Experimental | Strategy Training Group Participants will receive training in specific cognitive strategies to improve balance and gait. This will include visual cues, verbal instructions, and mental rehearsal techniques. Receives: Other: Strategy Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
10-Meter Walk Test (10MWT)
The 10-Meter Walk Test (10MWT) is an effective instrument that is applied to determine the walking speed and functional mobility in different populations.
Measured: 6 weeks
Tandem Stance Test
Tandem Stance Test is one of the essential clinical tests of balance and postural stability particularly among older adults. It involves getting a person to stand on their heels to toes and this is used to determine people who are at risk of falling.
Measured: 6 weeks
Pastor Test (Shoulder Tug)
Pastor Test (Shoulder Tug test) is a test used to determine the shoulder stability (especially the anterior shoulder instability). In the test, the examiner pulls the patient using his arm as he keeps the shoulder constant to reveal too much movement or pain.
Measured: 6 weeks
30 sec Chair Test
30 sec Chair Test; A popular test for assessing lower body strength, balance, and functional mobility especially in older adults is the chair test. It gauges a person's capacity to carry out daily tasks on their own by timing how long it takes them to get up from a sitting position and sit down again.
Measured: 6 weeks
Retropulsion Test
Retropulsion Test is a clinical examination, which is mainly applied to determine the postural stability and balance in a person, particularly the people with Parkinson disease. In this test, the examiner smoothly pulls the shoulders of the patient in the standing position where the patient stands in a relaxed position, and the examiner sees whether the patient can balance or not.
Measured: 6 weeks
Unified Parkinson's Disease Rating Scale (UPDRS)
Unified Parkinson Disease Rating Scale (UPDRS) as one of the important assessment instruments in the study of Parkinson disease and its clinical application. (UPDRS) scale is a comprehensive tool, employed to assess treatment issues related to the treatment of the Parkinson disease, the daily life activities as well as the motor and non-motor symptoms.
Measured: 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Mar 2026
- Study startMar 2026 (estimated)
- Primary completionMay 2026 (estimated)
- Study completionMay 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Parkinson's Disease (PD)Studies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 42 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Arnab Altaf, MS-PT, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07484451
- Sponsor's protocol ID
- REC/RCR&AHS/B43-098
- Status last verified
- Mar 2026
- First submitted
- 16 Mar 2026
- Last updated
- 20 Mar 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Strategy Training Versus Proprioceptive Neuromuscular Facilitation Technique on Balance, Gait, and Functional Independence in Patients With Parkinson's Disease
- ClinicalTrials.gov ID
- NCT07484451
- Acronym / sponsor ID
- REC/RCR&AHS/B43-098
- Conditions
- Parkinson's Disease (PD)
- Keywords
- Parkinson's disease, PNF, strategy-based training, ADLs
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 42 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- Mar 2026 (estimated)
- Primary completion
- May 2026 (estimated)
- Study completion
- May 2026 (estimated)
- First posted
- 20 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial aims to compare the effects of Strategy Training and Proprioceptive Neuromuscular Facilitation (PNF) on balance, gait, and functional independence in patients with Parkinson's disease. Parkinson's disease leads to impaired motor function, reduced balance, and decreased independence. Physiotherapy interventions such as strategy-based training and PNF may help improve mobility and functional performance. Participants will be randomly assigned to two groups: one receiving Strategy Training and the other receiving PNF intervention. Outcome measures including balance tests, gait assessment, and functional independence scales will be evaluated before and after treatment. The study aims to determine which intervention is more effective in improving functional outcomes in Parkinson's disease patients.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group A: PNF Technique | Experimental | Other: PNF TechniqueParticipants will undergo PNF techniques targeting the muscles involved in balance and gait. This may include diagonal patterns, facilitation techniques, and proprioceptive neuromuscular facilitation holds. |
| Group B: Strategy training | Experimental | Other: Strategy TrainingStrategy Training Group Participants will receive training in specific cognitive strategies to improve balance and gait. This will include visual cues, verbal instructions, and mental rehearsal techniques. |
Who may qualify
- Ages
- 40 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| PNF TechniqueParticipants will undergo PNF techniques targeting the muscles involved in balance and gait. This may include diagonal patterns, facilitation techniques, and proprioceptive neuromuscular facilitation holds. | Other | Group A: PNF Technique |
| Strategy TrainingStrategy Training Group Participants will receive training in specific cognitive strategies to improve balance and gait. This will include visual cues, verbal instructions, and mental rehearsal techniques. | Other | Group B: Strategy training |
Primary outcome
10-Meter Walk Test (10MWT)
Time frame: 6 weeks
The 10-Meter Walk Test (10MWT) is an effective instrument that is applied to determine the walking speed and functional mobility in different populations.
Tandem Stance Test
Time frame: 6 weeks
Tandem Stance Test is one of the essential clinical tests of balance and postural stability particularly among older adults. It involves getting a person to stand on their heels to toes and this is used to determine people who are at risk of falling.
Pastor Test (Shoulder Tug)
Time frame: 6 weeks
Pastor Test (Shoulder Tug test) is a test used to determine the shoulder stability (especially the anterior shoulder instability). In the test, the examiner pulls the patient using his arm as he keeps the shoulder constant to reveal too much movement or pain.
30 sec Chair Test
Time frame: 6 weeks
30 sec Chair Test; A popular test for assessing lower body strength, balance, and functional mobility especially in older adults is the chair test. It gauges a person's capacity to carry out daily tasks on their own by timing how long it takes them to get up from a sitting position and sit down again.
Retropulsion Test
Time frame: 6 weeks
Retropulsion Test is a clinical examination, which is mainly applied to determine the postural stability and balance in a person, particularly the people with Parkinson disease. In this test, the examiner smoothly pulls the shoulders of the patient in the standing position where the patient stands in a relaxed position, and the examiner sees whether the patient can balance or not.
Unified Parkinson's Disease Rating Scale (UPDRS)
Time frame: 6 weeks
Unified Parkinson Disease Rating Scale (UPDRS) as one of the important assessment instruments in the study of Parkinson disease and its clinical application. (UPDRS) scale is a comprehensive tool, employed to assess treatment issues related to the treatment of the Parkinson disease, the daily life activities as well as the motor and non-motor symptoms.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Mar 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Arnab Altaf, MS-PT principal investigator
Riphah International University
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing PNF Technique and Strategy Training in people with Parkinson's Disease (PD), run by Riphah International University at 2 sites in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 20 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Arnab Altaf, MS-PT (+923064585776, arnab.altaf@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
10-Meter Walk Test (10MWT) (time frame: 6 weeks). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Mar 2026.