Nursing EducationNCT07488390
Escape Room Simulation vs Case-Based Learning for Vital Sign Measurement in Nursing Students
A study testing Escape Room Simulation and Case-Based Learning in people with Nursing Education and Vital Signs, run by Acibadem University at 1 site in Turkey (Türkiye).
Trial summary
This study compares two teaching methods for helping first-year nursing students learn how to select the correct anatomical site for vital sign measurement in different clinical conditions. Students will be randomly assigned to one of two groups: an escape room simulation group or a case-based learning group. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Nursing Education, Vital Signs, Simulation Based Learning
- What is being tested?
- Escape Room Simulation and Case-Based Learning
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 45 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Jan 2026to 30 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Enrolled as a first-year nursing student in the "Health Assessment" course at Acibadem Mehmet Ali Aydinlar University in the 2025-2026 academic year
- Having attended the vital signs lecture and laboratory session
- Not having graduated from a vocational health high school
- Willing to participate voluntarily
Who cannot join
- Incomplete data collection forms
- Absence from the post-test measurement (T2)
- Voluntary withdrawal from the study
Trial locations and contacts
1 site in 1 country.
Turkey (Türkiye)1 site
Acibadem Mehmet Ali Aydinlar University
Istanbul, Kayışdağı Caddesi, 34752
About this study
Official title: Selecting the Correct Anatomical Site for Vital Sign Measurement in Different Clinical Conditions: A Mixed-Methods Study Based on Escape Room Simulation Experience
This study compares two teaching methods for helping first-year nursing students learn how to select the correct anatomical site for vital sign measurement in different clinical conditions. Students will be randomly assigned to one of two groups: an escape room simulation group or a case-based learning group. Both groups will receive the same clinical content. Knowledge levels and anxiety will be measured before and after the intervention. Students in the escape room group will also complete scales measuring their gaming experience and satisfaction with learning. Additionally, focus group interviews will be conducted with escape room participants to explore their learning experiences in depth. The study uses a sequential explanatory mixed-methods design.
Read the detailed description
This sequential explanatory mixed-methods study aims to compare the effects of an escape room simulation and case-based learning on first-year nursing students' knowledge and anxiety regarding the selection of the correct anatomical site for vital sign measurement across different clinical conditions.
The study will be conducted at Acibadem Mehmet Ali Aydinlar University, Department of Nursing and the CASE Advanced Simulation and Education Center during the 2025-2026 academic year fall semester.
Eligible participants are first-year nursing students enrolled in the "Health Assessment" course (N≈101). Participants will be randomly assigned using a computer-generated random number table to either the intervention group (escape room simulation) or the control group (case-based learning). Both groups will work through identical clinical case content involving conditions such as post-mastectomy status, arteriovenous fistula, hemiplegia, oxygen therapy, obesity, and nail polish presence.
In the intervention group, students will solve clinical scenarios through an escape room format in teams of 4-5, followed by a 30-minute structured debriefing session. In the control group, students will discuss the same cases in educator-guided sessions lasting 30-35 minutes.
Data will be collected using a Descriptive Characteristics Form, a Knowledge Test (10-item multiple choice, pre- and post-test), the Gameful Experience Scale (GAMEX), the Student Satisfaction and Self-Confidence in Learning Scale, and the State-Trait Anxiety Inventory (STAI). Qualitative data will be collected via semi-structured focus group interviews with escape room participants and analyzed using content analysis.
Sample size was calculated using G*Power 3.1 (α=0.05, power=0.80, Cohen's d=0.60), indicating a minimum of 45 participants per group (total n=90). The study will be conducted in accordance with the CONSORT guidelines and ethical principles of the Declaration of Helsinki.
- Conditions
- Nursing Education, Vital Signs, Simulation Based Learning
- Being tested
- Escape Room Simulation, Case-Based Learning
- Keywords
- escape room, nursing student, vital signs, simulation based learning experience
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Escape Room SimulationBehavioural
A vital sign-themed escape room simulation in which students work in teams to solve clinical scenarios requiring selection of the correct anatomical measurement site. Followed by structured debriefing.
Case-Based LearningBehavioural
Educator-guided group discussion of identical clinical cases involving vital sign measurement site selection under various clinical conditions.
| Study group | Role | What they receive |
|---|---|---|
| Escape Room Simulation Group | Experimental | First-year nursing students assigned to this group will participate in an escape room simulation in teams of 4-5 students. They will solve clinical scenarios related to vital sign measurement site selection. The session lasts approximately 15 minutes, followed by a 30-minute structured debriefing. Receives: Behavioral: Escape Room Simulation |
| Case-Based Learning Group | Active comparator | Students assigned to this group will discuss the same clinical cases in educator-guided case-based learning sessions lasting 30-35 minutes. The instructor will facilitate discussion using guiding questions. Receives: Behavioral: Case-Based Learning |
What is being measured
The primary outcome is the main question the study is designed to answer.
Knowledge Test Score
A 10-item multiple choice test assessing students' ability to select the correct anatomical site for vital sign measurement in different clinical conditions. Each correct answer scores 1 point (total: 0-10).
Measured: Baseline (pre-intervention) and immediately after intervention (approximately 1 hour)
Secondary outcomes (1)
State Anxiety Level
Measured with the State-Trait Anxiety Inventory (STAI) State Anxiety subscale (20 items, score range 20-80).
Measured: Baseline and immediately after intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Mar 2026
- Study start1 Jan 2026
- Primary completion30 Mar 2026 (estimated)
- Study completion30 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Nursing EducationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Two parallel groups: intervention group receiving escape room simulation and control group receiving case-based learning. Both groups work through identical clinical case content simultaneously but with different instructional strategies.
- Masking
- None (open label)
- Enrolment
- 45 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Acibadem University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07488390
- Sponsor's protocol ID
- ATADEK-2025-16/620
- Status last verified
- Jan 2026
- First submitted
- 18 Mar 2026
- Last updated
- 23 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data will not be shared in order to protect the privacy and confidentiality of student participants, in accordance with the ethical principles outlined in the study protocol.
Publications
Rafi A, Habibi A, Kalantarion M. Traditional medical education under siege: the revolutionary integration of virtual reality and gamification in medical escape rooms. BMC Med Educ. 2025 Jul 1;25(1):898. doi: 10.1186/s12909-025-07367-5.
PubMed 40598049Ghiamikeshtgar N, Ghaljaei F, Ghaljeh M, Taherizade B, Mahmoodi N, Sharifi S. The effect of escape room clinical evaluation method on satisfaction, learning, and preparedness to practice as interns of nursing students: A quasi-experimental quantitative study. J Educ Health Promot. 2024 Jul 11;13:225. doi: 10.4103/jehp.jehp_711_23. eCollection 2024.
PubMed 39297109
Study at a glance
From the registry record, last updated by the sponsor on 23 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Selecting the Correct Anatomical Site for Vital Sign Measurement in Different Clinical Conditions: A Mixed-Methods Study Based on Escape Room Simulation Experience
- ClinicalTrials.gov ID
- NCT07488390
- Acronym / sponsor ID
- ATADEK-2025-16/620
- Conditions
- Nursing Education, Vital Signs, Simulation Based Learning
- Keywords
- escape room, nursing student, vital signs, simulation based learning experience
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 45 participants (estimated)
- Lead sponsor
- Acibadem UniversityUniversity, hospital or other
- Study start
- 1 Jan 2026 (actual)
- Primary completion
- 30 Mar 2026 (estimated)
- Study completion
- 30 Dec 2026 (estimated)
- First posted
- 23 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study compares two teaching methods for helping first-year nursing students learn how to select the correct anatomical site for vital sign measurement in different clinical conditions. Students will be randomly assigned to one of two groups: an escape room simulation group or a case-based learning group. Both groups will receive the same clinical content. Knowledge levels and anxiety will be measured before and after the intervention. Students in the escape room group will also complete scales measuring their gaming experience and satisfaction with learning. Additionally, focus group interviews will be conducted with escape room participants to explore their learning experiences in depth. The study uses a sequential explanatory mixed-methods design.
Detailed description
This sequential explanatory mixed-methods study aims to compare the effects of an escape room simulation and case-based learning on first-year nursing students' knowledge and anxiety regarding the selection of the correct anatomical site for vital sign measurement across different clinical conditions.
The study will be conducted at Acibadem Mehmet Ali Aydinlar University, Department of Nursing and the CASE Advanced Simulation and Education Center during the 2025-2026 academic year fall semester.
Eligible participants are first-year nursing students enrolled in the "Health Assessment" course (N≈101). Participants will be randomly assigned using a computer-generated random number table to either the intervention group (escape room simulation) or the control group (case-based learning). Both groups will work through identical clinical case content involving conditions such as post-mastectomy status, arteriovenous fistula, hemiplegia, oxygen therapy, obesity, and nail polish presence.
In the intervention group, students will solve clinical scenarios through an escape room format in teams of 4-5, followed by a 30-minute structured debriefing session. In the control group, students will discuss the same cases in educator-guided sessions lasting 30-35 minutes.
Data will be collected using a Descriptive Characteristics Form, a Knowledge Test (10-item multiple choice, pre- and post-test), the Gameful Experience Scale (GAMEX), the Student Satisfaction and Self-Confidence in Learning Scale, and the State-Trait Anxiety Inventory (STAI). Qualitative data will be collected via semi-structured focus group interviews with escape room participants and analyzed using content analysis.
Sample size was calculated using G*Power 3.1 (α=0.05, power=0.80, Cohen's d=0.60), indicating a minimum of 45 participants per group (total n=90). The study will be conducted in accordance with the CONSORT guidelines and ethical principles of the Declaration of Helsinki.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Two parallel groups: intervention group receiving escape room simulation and control group receiving case-based learning. Both groups work through identical clinical case content simultaneously but with different instructional strategies.
| Arm | Type | Receives |
|---|---|---|
| Escape Room Simulation Group | Experimental | Behavioral: Escape Room SimulationFirst-year nursing students assigned to this group will participate in an escape room simulation in teams of 4-5 students. They will solve clinical scenarios related to vital sign measurement site selection. The session lasts approximately 15 minutes, followed by a 30-minute structured debriefing. |
| Case-Based Learning Group | Active comparator | Behavioral: Case-Based LearningStudents assigned to this group will discuss the same clinical cases in educator-guided case-based learning sessions lasting 30-35 minutes. The instructor will facilitate discussion using guiding questions. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Enrolled as a first-year nursing student in the "Health Assessment" course at Acibadem Mehmet Ali Aydinlar University in the 2025-2026 academic year
- Having attended the vital signs lecture and laboratory session
- Not having graduated from a vocational health high school
- Willing to participate voluntarily
Key exclusion criteria (3 listed)
- Incomplete data collection forms
- Absence from the post-test measurement (T2)
- Voluntary withdrawal from the study
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Escape Room SimulationA vital sign-themed escape room simulation in which students work in teams to solve clinical scenarios requiring selection of the correct anatomical measurement site. Followed by structured debriefing. | Behavioural | Escape Room Simulation Group |
| Case-Based LearningEducator-guided group discussion of identical clinical cases involving vital sign measurement site selection under various clinical conditions. | Behavioural | Case-Based Learning Group |
Primary outcome
Knowledge Test Score
Time frame: Baseline (pre-intervention) and immediately after intervention (approximately 1 hour)
A 10-item multiple choice test assessing students' ability to select the correct anatomical site for vital sign measurement in different clinical conditions. Each correct answer scores 1 point (total: 0-10).
1 secondary outcome
State Anxiety Level
Time frame: Baseline and immediately after intervention
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Mar 2026.
- Background: PubMed 40598049Rafi A, Habibi A, Kalantarion M. Traditional medical education under siege: the revolutionary integration of virtual reality and gamification in medical escape rooms. BMC Med Educ. 2025 Jul 1;25(1):898. doi: 10.1186/s12909-025-07367-5.
- Background: PubMed 39297109Ghiamikeshtgar N, Ghaljaei F, Ghaljeh M, Taherizade B, Mahmoodi N, Sharifi S. The effect of escape room clinical evaluation method on satisfaction, learning, and preparedness to practice as interns of nursing students: A quasi-experimental quantitative study. J Educ Health Promot. 2024 Jul 11;13:225. doi: 10.4103/jehp.jehp_711_23. eCollection 2024.
- Individual participant dataSharing planned: No. Individual participant data will not be shared in order to protect the privacy and confidentiality of student participants, in accordance with the ethical principles outlined in the study protocol.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Escape Room Simulation and Case-Based Learning in people with Nursing Education and Vital Signs, run by Acibadem University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 23 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Knowledge Test Score (time frame: Baseline (pre-intervention) and immediately after intervention (approximately 1 hour)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07488390, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Mar 2026.