SleepNCT07489417
Impact of Sleep Restriction on Blood Pressure Reactivity
A study testing Sleep Restriction in people with Sleep and Blood Pressure, run by University of Missouri-Columbia at 1 site in United States.
Trial summary
The purpose of the research study is to examine the effects of shortened sleep on blood pressure. Read more about this study
- Who is it for?
- Ages 18 to 45 yearsHealthy volunteers can take part
- Conditions the study is for
- Sleep, Blood Pressure
- What is being tested?
- Sleep Restriction
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 45 participants
- Where
- 1 siteUnited States
- Study dates
- 4 Mar 2026to Aug 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 45 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy adult men and women
- 18-45 years of age
- BMI < 25 kg/m² (normal weight group) or ≥ 30 kg/m² (obesity group)
- Non-pregnant, non-breastfeeding, and non-nicotine users
- Self-reported history of normal sleep duration (7-9 hours/night) and bedtime prior to midnight
- Premenopausal
Who cannot join
- No acute or chronic conditions
- Taking no medications known to affect sleep, autonomic, metabolic, or cardiovascular function
- Self-reported history of irregular sleep
- Self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, history of alcoholism or substance abuse, major cardiovascular event or surgical procedure within the past three months, or hypertension
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
University of Missouri
Columbia, Missouri, 65211
Jacqueline Limberg, 573-882-2544, limberglab@missouri.edu
Jacqueline Limberg
About this study
The purpose of the research study is to examine the effects of shortened sleep on blood pressure.
- Conditions
- Sleep, Blood Pressure
- Being tested
- Sleep Restriction
- Keywords
- Sleep, Blood pressure
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Sleep RestrictionBehavioural
You will be asked to shorten your sleep to four hours.
| Study group | Role | What they receive |
|---|---|---|
| Sleep Restriction | Experimental | You will be asked to shorten your sleep to four hours. Receives: Behavioral: Sleep Restriction |
| Normal Sleep | No intervention | You will be asked to sleep for 7-9 hours. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Mean Blood Pressure
Mean Blood pressure
Measured: Baseline and during the last 1-minute of stress
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Mar 2026
- Study start4 Mar 2026
- Primary completionAug 2027 (estimated)
- Study completionAug 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for SleepStudies of the same condition, open and under way.
- More trials run by University of Missouri-ColumbiaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Non-randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 45 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Missouri-Columbia
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Jacqueline K Limberg, PhD, University of Missouri-Columbia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07489417
- Sponsor's protocol ID
- 2132616
- Status last verified
- Mar 2026
- First submitted
- 15 Mar 2026
- Last updated
- 28 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 28 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Impact of Sleep Restriction on Blood Pressure Reactivity
- ClinicalTrials.gov ID
- NCT07489417
- Acronym / sponsor ID
- 2132616
- Conditions
- Sleep, Blood Pressure
- Keywords
- Sleep, Blood pressure
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 45 participants (estimated)
- Lead sponsor
- University of Missouri-ColumbiaUniversity, hospital or other
- Study start
- 4 Mar 2026 (actual)
- Primary completion
- Aug 2027 (estimated)
- Study completion
- Aug 2027 (estimated)
- First posted
- 24 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of the research study is to examine the effects of shortened sleep on blood pressure.
Study design
- Primary purpose
- Basic science
- Allocation
- Non-randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Sleep Restriction | Experimental | Behavioral: Sleep RestrictionYou will be asked to shorten your sleep to four hours. |
| Normal Sleep | No intervention | –You will be asked to sleep for 7-9 hours. |
Who may qualify
- Ages
- 18 to 45 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (6 listed)
- Healthy adult men and women
- 18-45 years of age
- BMI < 25 kg/m² (normal weight group) or ≥ 30 kg/m² (obesity group)
- Non-pregnant, non-breastfeeding, and non-nicotine users
- Self-reported history of normal sleep duration (7-9 hours/night) and bedtime prior to midnight
Key exclusion criteria (4 listed)
- No acute or chronic conditions
- Taking no medications known to affect sleep, autonomic, metabolic, or cardiovascular function
- Self-reported history of irregular sleep
- Self-reported history of hepatic, renal, pulmonary, cardiovascular, or neurological disease, stroke or neurovascular disease, bleeding/clotting disorders, sleep apnea or other sleep disorders, diabetes, history of alcoholism or substance abuse, major cardiovascular event or surgical procedure within the past three months, or hypertension
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Sleep RestrictionYou will be asked to shorten your sleep to four hours. | Behavioural | Sleep Restriction |
Primary outcome
Mean Blood Pressure
Time frame: Baseline and during the last 1-minute of stress
Mean Blood pressure
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Jul 2026.
- Individual participant dataSharing planned: Undecided
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Healthy Adult Participants
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Sleep Restriction in people with Sleep and Blood Pressure, run by University of Missouri-Columbia at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 28 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Jacqueline Limberg (1-573-882-2544, limberglab@missouri.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mean Blood Pressure (time frame: Baseline and during the last 1-minute of stress). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Jul 2026.