AzTrials
AzTrials

Educational ProblemsARTEDUNCT07489859

Nurse vs Physician Artery Cannulation

A study testing Radial artery catheterization done by nurse and Radial artery catheterization done by physician in people with Educational Problems and Catheterization, run by Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s..

Not yet recruiting

Opening soon. The study is approved but enrolment has not started yet. Sites may already take enquiries.

Official record
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Trial summary

This prospective controlled clinical trial evaluates the effectiveness and safety of radial artery cannulation using the Seldinger technique under ultrasound guidance when performed by two different operator groups: experienced physicians and trained registered nurses. Read more about this study

Who is it for?
Ages 18 years and older
What is being tested?
Radial artery catheterization done by nurse and Radial artery catheterization done by physician
Type of treatment
Surgery or procedure
Could I receive a placebo?
No, everyone receives an active treatment
How many people
560 participants
Where
No sites listed yet
Study dates
1 May 2026to 1 Aug 2028
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • No healthy volunteers
  • Adult, Older adult

Who may be able to join

  • Nurse with successful completion of the predefined radial artery catheterization educational module
  • Czech board certified anaesthesiologist with obtained competency for radial artery catheterization.

Who cannot join

  • Absence of competency for radial artery catheterization.

About this study

Official title: Nurse-performed Versus Physician-performed Radial Artery Cannulation: a Multicenter Randomized Non-inferiority Trial

This prospective controlled clinical trial evaluates the effectiveness and safety of radial artery cannulation using the Seldinger technique under ultrasound guidance when performed by two different operator groups: experienced physicians and trained registered nurses. The study aims to determine whether a structured, competency-based training program enables nurses without prior experience in arterial cannulation to achieve comparable outcomes to physicians in terms of first-attempt success rate, procedural efficiency, and complication rates.

Read the detailed description

This study is a prospective, controlled clinical trial designed to compare the performance of radial artery cannulation using the Seldinger technique under ultrasound guidance between two predefined operator groups: experienced physicians and trained registered nurses. The trial is conducted in tertiary-care hospital settings in accordance with the Declaration of Helsinki and Good Clinical Practice guidelines. 

Radial artery cannulation is a commonly performed invasive procedure used for continuous blood pressure monitoring and arterial blood sampling in perioperative and critical care settings. While traditionally performed by physicians, task-sharing strategies supported by structured training programs may expand procedural capacity while maintaining patient safety. 

In this study, physicians in the control group are board-certified anaesthesiologists or intensivists with established experience in arterial cannulation. The intervention group consists of registered nurses who have no prior experience with arterial cannulation but have successfully completed a structured, competency-based educational program. This program incorporates theoretical instruction, simulation-based training, and supervised clinical practice, based on principles of deliberate practice and mastery learning. 

All procedures are performed using a standardized Seldinger technique with ultrasound guidance and identical equipment, under uniform clinical conditions. Patient preparation, sterile technique, and procedural protocols are standardized across both groups. A supervising physician is immediately available during all procedures to ensure patient safety. 

The primary outcome is first-attempt success rate, defined as successful arterial cannulation following a single skin puncture with confirmation by arterial waveform. Secondary outcomes include total procedure time, overall success rate, number of attempts, and incidence of complications such as hematoma, catheter dysfunction, distal ischemia, and need for rescue intervention. 

The study aims to determine whether nurses trained through a structured educational program can achieve procedural outcomes comparable to experienced physicians. The findings may support the implementation of competency-based training pathways and task-sharing models in vascular access procedures, potentially improving healthcare efficiency while maintaining high standards of patient safety. 

Being tested
Radial artery catheterization done by nurse, Radial artery catheterization done by physician
Keywords
education, nurse competency, arterial catheterization, seldinger method, competency based education, simulation based medical education

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Radial artery catheterization done by nurseProcedure or surgery

    Cannulation of a radial artery using Seldinger method by nurse.

  • Radial artery catheterization done by physicianProcedure or surgery

    Cannulation of a radial artery using Seldinger method by physician.

Study groups in NCT07489859
Study groupRoleWhat they receive
NurseExperimentalCannulation of a radial artery is done by nurse.
Receives: Procedure: Radial artery catheterization done by nurse
PhysicianActive comparatorCannulation of a radial artery is done by physician.
Receives: Procedure: Radial artery catheterization done by physician

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. First successful attempt

    Number of first successful attempt

    Measured: From the first puncture of the patient's skin until the end of catheterization for maximum time of 20 minutes

Secondary outcomes (2)
  1. Time to complete catheterization

    Time from firs puncture of a patient's skin to complete successful catheter insertion.

    Measured: From the first puncture of the patient's skin until the end of catheterization for maximum time of 20 minutes

  2. Complication rate

    Number of complications related to radial artery catheterization.

    Measured: From the first puncture of the patient's skin until the extraction of the catheter for maximum time of 7 days

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted24 Mar 2026
  2. Study start1 May 2026 (estimated)
  3. Primary completion1 May 2027 (estimated)
  4. Study completion1 Aug 2028 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Other
Allocation
Randomised
Intervention model
Parallel groups
Masking
None (open label)
Enrolment
560 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT07489859
Sponsor's protocol ID
ARTEDU
Acronym
ARTEDU
Status last verified
Mar 2026
First submitted
18 Mar 2026
Last updated
31 Mar 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Yes

Questions about this trial

What is this clinical trial studying?

A study testing Radial artery catheterization done by nurse and Radial artery catheterization done by physician in people with Educational Problems and Catheterization, run by Masarykova Nemocnice v Usti nad Labem, Krajska Zdravotni a.s..

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: opening soon, as of the sponsor's last update on 31 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

First successful attempt (time frame: From the first puncture of the patient's skin until the end of catheterization for maximum time of 20 minutes). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Mar 2026.

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