Cerebro Vascular DiseaseNCT07493694
Clinico-radiological Correlations in Cerebro-VASCULAR Disease
An observational study of Cerebro Vascular Disease, run by IRCCS San Raffaele.
Trial summary
This observational retrospective and prospective registry aims to explore the relationships between clinical manifestations and radiological findings in cerebrovascular diseases. Read more about this study
- Who is it for?
- Ages 18 to 100 years
- Conditions the study is for
- Cerebro Vascular Disease
- How many people
- 1,143 participants
- Where
- No sites listed yet
- Study dates
- Apr 2026to Apr 2046
- How long will I take part?
- 20 Years
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 100 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: The registry will focus on adults aged 18 to 100 of both genders diagnosed with various cerebrovascular diseases based on clinical and imaging evaluations. Participants will be selected from a retrospective registry of patients who have undergone MRI or CT scans for clinical indications. In addition to the retrospective cohort, the registry will also include a prospective component, enrolling newly diagnosed patients who meet the same eligibility criteria.
Who may be able to join
- Age Range: 18-100 years old.
- Must have undergone a CT or MRI scan of the central nervous system (CNS) (for clinical reasons).
Who cannot join
- Alternative diagnosis to vascular pathology that explains clinical symptoms.
- MRI or CT non-diagnostic or non-evaluable MRI due to motion artifacts.
About this study
Official title: Clinico-radiological Correlations in Cerebro-VASCULAR Disease: Toward a BetteR understAndINg of Their Heterogeneous Manifestations in a Retrospective and Prospective Observational Registry
This observational retrospective and prospective registry aims to explore the relationships between clinical manifestations and radiological findings in cerebrovascular diseases. These conditions are characterized by heterogeneous radiological presentations and different etiologies, posing challenges for accurate diagnosis and effective treatment. Understanding these correlations is essential for advancing diagnostic accuracy and therapeutic strategies.
- Conditions
- Cerebro Vascular Disease
What is being measured
The primary outcome is the main question the study is designed to answer.
Proportion of patients with each key MRI/CT finding in cerebrovascular disease (lesion location, vessel involvement, hemorrhagic transformation)
Primary Outcome Measure:
Diagnostic imaging trends in cerebrovascular disease Description: Key imaging findings from first MRI/CT (e.g., lesion location, vessel involvement; %).
Measured: Baseline (at diagnosis), up to 20 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Mar 2026
- Study startApr 2026 (estimated)
- Primary completionApr 2046 (estimated)
- Study completionApr 2046 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cerebro Vascular DiseaseStudies of the same condition, open and under way.
- More trials run by IRCCS San RaffaeleThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Other
- Enrolment
- 1,143 participants (estimated)
- Target duration
- 20 Years
Sponsor and investigators
- Lead sponsor
- IRCCS San Raffaele
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Anna del Poggio, IRCCS San Raffaele
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07493694
- Sponsor's protocol ID
- VASCULAR-BRAIN
- Status last verified
- Mar 2026
- First submitted
- 5 Mar 2026
- Last updated
- 30 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 30 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Clinico-radiological Correlations in Cerebro-VASCULAR Disease: Toward a BetteR understAndINg of Their Heterogeneous Manifestations in a Retrospective and Prospective Observational Registry
- ClinicalTrials.gov ID
- NCT07493694
- Acronym / sponsor ID
- VASCULAR-BRAIN
- Conditions
- Cerebro Vascular Disease
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 1,143 participants (estimated)
- Lead sponsor
- IRCCS San RaffaeleUniversity, hospital or other
- Study start
- Apr 2026 (estimated)
- Primary completion
- Apr 2046 (estimated)
- Study completion
- Apr 2046 (estimated)
- First posted
- 25 Mar 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This observational retrospective and prospective registry aims to explore the relationships between clinical manifestations and radiological findings in cerebrovascular diseases. These conditions are characterized by heterogeneous radiological presentations and different etiologies, posing challenges for accurate diagnosis and effective treatment. Understanding these correlations is essential for advancing diagnostic accuracy and therapeutic strategies.
Study design
- Observational model
- Other
- Time perspective
- Other
- Target follow-up
- 20 Years
Who may qualify
- Ages
- 18 to 100 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- The registry will focus on adults aged 18 to 100 of both genders diagnosed with various cerebrovascular diseases based on clinical and imaging evaluations. Participants will be selected from a retrospective registry of patients who have undergone MRI or CT scans for clinical indications. In addition to the retrospective cohort, the registry will also include a prospective component, enrolling newly diagnosed patients who meet the same eligibility criteria.
Key inclusion criteria (2 listed)
- Age Range: 18-100 years old.
- Must have undergone a CT or MRI scan of the central nervous system (CNS) (for clinical reasons).
Key exclusion criteria (2 listed)
- Alternative diagnosis to vascular pathology that explains clinical symptoms.
- MRI or CT non-diagnostic or non-evaluable MRI due to motion artifacts.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Proportion of patients with each key MRI/CT finding in cerebrovascular disease (lesion location, vessel involvement, hemorrhagic transformation)
Time frame: Baseline (at diagnosis), up to 20 years
Primary Outcome Measure: Diagnostic imaging trends in cerebrovascular disease Description: Key imaging findings from first MRI/CT (e.g., lesion location, vessel involvement; %).
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Mar 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
An observational study of Cerebro Vascular Disease, run by IRCCS San Raffaele.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 30 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Proportion of patients with each key MRI/CT finding in cerebrovascular disease (lesion location, vessel involvement, hemorrhagic transformation) (time frame: Baseline (at diagnosis), up to 20 years). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Mar 2026.