Ulnar NerveNCT07515911
Comparison of Ultrasound and Anatomic Landmark Techniques of the Ulnar and Posterior Tibial Nerves
An observational study of Ulnar Nerve, run by Mayo Clinic at 1 site in United States.
Trial summary
The purpose of this study is to determine whether placement of stimulating electrodes over the ulnar nerve is important for proper delivery of current leading to stimulation of intrinsic hand muscles. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Ulnar Nerve
- What is being tested?
- Hand measurements and Foot/ankle measurements
- How many people
- 40 participants
- Where
- 1 siteUnited States
- Study dates
- 2 Sep 2026to Jan 2027
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Mayo Clinic employees who meet inclusion/exclusion criteria
Who may be able to join
- English speaking
Who cannot join
- History of ulnar neuropathy or ulnar nerve or wrist surgery (i.e. carpal tunnel)
- Upper extremity edema
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Mayo Clinic
Jacksonville, Florida, 32224
Ally R. Sapin, MS, 904-956-3328
J. Ross Renew, MD
About this study
The purpose of this study is to determine whether placement of stimulating electrodes over the ulnar nerve is important for proper delivery of current leading to stimulation of intrinsic hand muscles.
Read the detailed description
Placement of stimulating electrodes over the ulnar nerve is important for proper delivery of current leading to stimulation of intrinsic hand muscles. Accuracy may be improved with a better description of the precise location of the ulnar nerve. There may be a simple fraction of the wrist width that can be utilized to assist the busy practitioner with accurate placement of the stimulating electrodes over the ulnar nerve. It is expected that the ulnar groove, when easily identified, will be an accurate estimate (within 10% of total wrist width) of the ulnar nerve location.
- Conditions
- Ulnar Nerve
- Being tested
- Hand measurements, Foot/ankle measurements
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Hand measurementsOther
Ulnar right:
- Width of wrist
- Distance from radial side to middle of ulnar groove
- Photo of ulnar groove
- Grade ability to identify: easy, moderate-difficult, unable
- Ultrasound measurements
Ulnar left:
- Width of wrist
- Distance from radial side to middle of ulnar groove
- Photo of ulnar groove
- Grade ability to identify: easy, moderate-difficult, unable
- Ultrasound measurements
Foot/ankle measurementsOther
Posterior tibial right:
- Distance between prominence of medial malleolus and mid-Achilles tendon
- Distance artery point of maximal pulsation to posterior border of medial malleolus
- Distance artery point of maximal pulsation to medial border of Achilles tendon
- Photo taken after palpating posterior tibial artery
- Grade ability to identify: easy, moderate-difficult, unable
- Ultrasound measurements
Posterior tibial left:
- Distance between prominence of medial malleolus and mid-Achilles tendon
- Distance artery point of maximal pulsation to posterior border of medial malleolus
- Distance artery point of maximal pulsation to medial border of Achilles tendon
- Photo taken after palpating posterior tibial artery
- Grade ability to identify: easy, moderate-difficult, unable
- Ultrasound measurements
| Study group | Role | What they receive |
|---|---|---|
| Volunteers | Employee volunteers will have hand measurements obtained to help identify location of ulnar nerve. Receives: Other: Hand measurements; Other: Foot/ankle measurements |
What is being measured
The primary outcome is the main question the study is designed to answer.
Wrist width
Width of wrist will be measured with calipers and reported in inches
Measured: Baseline
Reliability of wrist width to locate ulnar nerve
Total number of times that the ulnar nerve, as identified with ultrasound, falls between 5-15% of the wrist width distance as measured from the ulnar side of the wrist
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 Apr 2026
- Study start2 Sep 2026
- Primary completionJan 2027 (estimated)
- Study completionJan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Ulnar NerveStudies of the same condition, open and under way.
- More trials run by Mayo ClinicThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Other
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Mayo Clinic
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, J. Ross Renew, M.D., Mayo Clinic
- Investigators
- J. Ross Renew, MD, Principal investigator, Mayo Clinic
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07515911
- Sponsor's protocol ID
- 25-013952
- Status last verified
- Sep 2026
- First submitted
- 31 Mar 2026
- Last updated
- 17 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 17 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Ultrasound and Anatomic Landmark Techniques of the Ulnar and Posterior Tibial Nerves
- ClinicalTrials.gov ID
- NCT07515911
- Acronym / sponsor ID
- 25-013952
- Conditions
- Ulnar Nerve
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- Mayo ClinicUniversity, hospital or other
- Study start
- 2 Sep 2026 (actual)
- Primary completion
- Jan 2027 (estimated)
- Study completion
- Jan 2027 (estimated)
- First posted
- 7 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to determine whether placement of stimulating electrodes over the ulnar nerve is important for proper delivery of current leading to stimulation of intrinsic hand muscles.
Detailed description
Placement of stimulating electrodes over the ulnar nerve is important for proper delivery of current leading to stimulation of intrinsic hand muscles. Accuracy may be improved with a better description of the precise location of the ulnar nerve. There may be a simple fraction of the wrist width that can be utilized to assist the busy practitioner with accurate placement of the stimulating electrodes over the ulnar nerve. It is expected that the ulnar groove, when easily identified, will be an accurate estimate (within 10% of total wrist width) of the ulnar nerve location.
Study design
- Observational model
- Other
- Time perspective
- Other
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Volunteers | – | Other: Hand measurements, Other: Foot/ankle measurementsEmployee volunteers will have hand measurements obtained to help identify location of ulnar nerve. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Mayo Clinic employees who meet inclusion/exclusion criteria
Key inclusion criteria (1 listed)
- English speaking
Key exclusion criteria (2 listed)
- History of ulnar neuropathy or ulnar nerve or wrist surgery (i.e. carpal tunnel)
- Upper extremity edema
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Hand measurementsUlnar right: * Width of wrist * Distance from radial side to middle of ulnar groove * Photo of ulnar groove o Grade ability to identify: easy, moderate-difficult, unable * Ultrasound measurements Ulnar left: * Width of wrist * Distance from radial side to middle of ulnar groove * Photo of ulnar groove o Grade ability to identify: easy, moderate-difficult, unable * Ultrasound measurements | Other | Volunteers |
| Foot/ankle measurementsPosterior tibial right: * Distance between prominence of medial malleolus and mid-Achilles tendon * Distance artery point of maximal pulsation to posterior border of medial malleolus * Distance artery point of maximal pulsation to medial border of Achilles tendon * Photo taken after palpating posterior tibial artery o Grade ability to identify: easy, moderate-difficult, unable * Ultrasound measurements Posterior tibial left: * Distance between prominence of medial malleolus and mid-Achilles tendon * Distance artery point of maximal pulsation to posterior border of medial malleolus * Distance artery point of maximal pulsation to medial border of Achilles tendon * Photo taken after palpating posterior tibial artery o Grade ability to identify: easy, moderate-difficult, unable * Ultrasound measurements | Other | Volunteers |
Primary outcome
Wrist width
Time frame: Baseline
Width of wrist will be measured with calipers and reported in inches
Reliability of wrist width to locate ulnar nerve
Time frame: Baseline
Total number of times that the ulnar nerve, as identified with ultrasound, falls between 5-15% of the wrist width distance as measured from the ulnar side of the wrist
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
J. Ross Renew, MD principal investigator
Mayo Clinic
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Ulnar Nerve, run by Mayo Clinic at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ally R. Sapin, MS (904-956-3328, sapin.alyssa@mayo.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Wrist width (time frame: Baseline). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Sep 2026.