Obesity & OverweightNCT07520929
Acute Sauna Session and Glucose Control
A study testing Infrared sauna session and Resting condition in people with Obesity & Overweight, run by University of Prince Edward Island at 1 site in Canada.
Trial summary
The goal of this clinical trial is to examine the effect of a single 40-minute sauna session on glucose control in individuals at risk for metabolic impairments. Research Questions: Can a single sauna session completed before a meal reduce the post-meal blood glucose response? Can a single sauna session improve… Read more about this study
- Who is it for?
- Ages 30 to 55 years
- Conditions the study is for
- Obesity & Overweight
- What is being tested?
- Infrared sauna session and Resting condition
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 15 participants
- Where
- 1 siteCanada
- Study dates
- 1 Dec 2025to 15 Apr 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 55 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Are 30-55 years old
- Have a body mass index of ≥ 27 kg/m2
- Have a waist size >102 cm (men) or >88 cm (women)
- Have access to transportation for the 2 experimental visits (e.g., car, public transit, or drop-off).
- Are cleared for participation based on the Physical Activity Readiness Questionnaire (PAR-Q+).
Who cannot join
- Take medications that affect blood sugar
- Exercise intensely 2+ times/week
- Have diabetes, heart issues, low blood sugar or pressure
- Are pregnant
- Regularly use saunas or other heat therapy 1+ times/week
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Canada1 site, 1 recruiting
- Recruiting
University of Prince Edward Island
Charlottetown, Prince Edward Island, C1A 4P3
Etienne Myette-Cote, PhD, 9026550756, emyette-cote@upei.ca
About this study
Official title: The Effects of an Acute Sauna Session on Glucose Control in Individuals at Risk for Metabolic Impairments
The goal of this clinical trial is to examine the effect of a single 40-minute sauna session on glucose control in individuals at risk for metabolic impairments.
Research Questions:
Read more
- Can a single sauna session completed before a meal reduce the post-meal blood glucose response?
- Can a single sauna session improve 24-hour glucose control?
Study Design:
Participants will complete two lab visits: one involving a sauna session and one placebo visit (resting condition). Researchers will compare the effects on glucose control using a continuous glucose monitor (CGM).
What Participants Will Do:
Attend a sauna familiarization session Have a CGM sensor placed on the upper arm Visit the lab twice (once for sauna, once for placebo) Consume three standardized meals at home after each session
Read the detailed description
At least 72 hours prior to the first trial, participants will complete a familiarization session consisting of two 20-minute infrared sauna exposures. The study employs a randomized crossover design, with each participant completing both experimental conditions-infrared sauna (two 20-minute sessions at 175°F / 79°C, separated by a 5-minute break) and seated rest (two 20-minute periods of quiet sitting, separated by a 5-minute break)-separated by at least 72 hours. On each trial day, participants will arrive at the laboratory at 7:50 a.m. after an overnight fast from 8:00 p.m., with water permitted throughout. Participants will wear a continuous glucose monitor (CGM) during both trial days. Baseline measurements of blood pressure, heart rate, and oral body temperature will be recorded, and food logs reviewed. Following the condition session, a sedentary recovery period will occur until 9:45 a.m., with repeated physiological measurements. Final measurements of blood pressure, heart rate, and oral body temperature will be collected prior to a standardized breakfast provided from 9:45 to 10:10 a.m. Participants will depart thereafter by car or public transportation and remain sedentary for the remainder of the day. Meals for the rest of the day, i.e., breakfast, lunch, dinner, and a bedtime snack, will be provided and identical across trial days. Participants will fast again from 9:00 p.m. until 9:00 a.m. the following morning.
- Conditions
- Obesity & Overweight
- Being tested
- Infrared sauna session, Resting condition
- Keywords
- sauna, heat-therapy, obesity, overweight, continuous glucose monitoring
- Medical subject headings
- Obesity, Overweight, Hyperthermia
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Infrared sauna sessionOther
Infrared sauna session (approximately 165°F; two 20-minute sessions separated by a 5-minute rest outside the sauna)
Resting conditionOther
Seated resting session (45 minutes outside the sauna)
| Study group | Role | What they receive |
|---|---|---|
| Sauna | Experimental | Infrared sauna session Receives: Other: Infrared sauna session |
| Resting control | Placebo comparator | Seated resting session Receives: Other: Resting condition |
What is being measured
The primary outcome is the main question the study is designed to answer.
Incremental 2-hour postprandial glucose area under the curve (Breakfast)
2-hour postprandial incremental AUC of CGM glucose above baseline, measured after the standardized breakfast consumed 45 minutes following the sauna or resting (control) session.
Measured: 2 hours
Secondary outcomes (11)
2-hour postprandial glucose area under the curve (Breakfast)
2-hour postprandial AUC of CGM glucose above baseline, measured after the standardized breakfast consumed 45 minutes following the sauna or resting (control) session.
Measured: 2 hours
Incremental 2-hour postprandial glucose area under the curve (Lunch)
Incremental 2-hour postprandial AUC of CGM glucose above baseline, measured after the standardized lunch consumed 225 minutes following the sauna or resting (control) session.
Measured: 2 hours
Incremental 2-hour postprandial glucose area under the curve (Dinner)
Incremental 2-hour postprandial AUC of CGM glucose above baseline, measured after the standardized lunch consumed 435 minutes following the sauna or resting (control) session.
Measured: 2 hours
Incremental 2-hour postprandial glucose area under the curve (Bedtime snack)
Incremental 2-hour postprandial AUC of CGM glucose above baseline, measured after the standardized lunch consumed 645 minutes following the sauna or resting (control) session.
Measured: 2 hours
Average incremental 2-hour postprandial glucose area under the curve (4 meals)
Average incremental 2-hour postprandial CGM glucose AUC above baseline, measured after each standardized meal consumed following the sauna or resting (control) session. The incremental AUC for all four meals will be summed and divided by four to calculate the average incremental postprandial response.
Measured: 2 hours
Time below range
Total time (minutes) during which CGM glucose values remained below 3.9 mmol/L over the 24-hour period following the sauna or resting (control) session.
Measured: 24 hours
Time above range
Total time (minutes) during which CGM glucose values remained above 7.8 mmol/L over the 24-hour period following the sauna or resting (control) session.
Measured: 24 hours
Time in range
Total time (minutes) during which CGM glucose values remained between 3.9 and 7.8 mmol/L over the 24-hour period following the sauna or resting (control) session.
Measured: 24 hours
Session-induced delta glucose
Change in CGM glucose during the 45-minute sauna or resting (control) session, calculated as the difference between post-session and pre-session values (Δ = post - pre).
Measured: 45 minutes
Fasting glucose
CGM glucose representing fasting levels the morning after the sauna or resting (control) session, computed as the mean glucose over the 15 minutes preceding the standardized breakfast.
Measured: 15 minutes
Daily mean glucose
CGM glucose average over the 24h period following the sauna or resting (control session).
Measured: 24 hours
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Apr 2026
- Study start1 Dec 2025
- Primary completion15 Dec 2026 (estimated)
- Study completion15 Apr 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Obesity & OverweightStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Single group
- Model description
- Randomized controlled trial (pilot study)
- Masking
- None (open label)
- Enrolment
- 15 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Prince Edward Island
- Sponsor type
- University, hospital or other
- Collaborators
- DexCom, Inc.
- Responsible party
- Sponsor
- Investigators
- Etienne Myette-Cote, Principal investigator, University of Prince Edward Island
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07520929
- Sponsor's protocol ID
- UPrinceEdwardIsland
- Status last verified
- Apr 2026
- First submitted
- 2 Apr 2026
- Last updated
- 9 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 9 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of an Acute Sauna Session on Glucose Control in Individuals at Risk for Metabolic Impairments
- ClinicalTrials.gov ID
- NCT07520929
- Acronym / sponsor ID
- UPrinceEdwardIsland
- Conditions
- Obesity & Overweight
- Keywords
- sauna, heat-therapy, obesity, overweight, continuous glucose monitoring
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 15 participants (estimated)
- Lead sponsor
- University of Prince Edward IslandUniversity, hospital or other
- Collaborators
- DexCom, Inc.
- Study start
- 1 Dec 2025 (actual)
- Primary completion
- 15 Dec 2026 (estimated)
- Study completion
- 15 Apr 2027 (estimated)
- First posted
- 9 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to examine the effect of a single 40-minute sauna session on glucose control in individuals at risk for metabolic impairments.
Research Questions:
- Can a single sauna session completed before a meal reduce the post-meal blood glucose response?
- Can a single sauna session improve 24-hour glucose control?
Study Design:
Participants will complete two lab visits: one involving a sauna session and one placebo visit (resting condition). Researchers will compare the effects on glucose control using a continuous glucose monitor (CGM).
What Participants Will Do:
Attend a sauna familiarization session Have a CGM sensor placed on the upper arm Visit the lab twice (once for sauna, once for placebo) Consume three standardized meals at home after each session
Detailed description
At least 72 hours prior to the first trial, participants will complete a familiarization session consisting of two 20-minute infrared sauna exposures. The study employs a randomized crossover design, with each participant completing both experimental conditions-infrared sauna (two 20-minute sessions at 175°F / 79°C, separated by a 5-minute break) and seated rest (two 20-minute periods of quiet sitting, separated by a 5-minute break)-separated by at least 72 hours. On each trial day, participants will arrive at the laboratory at 7:50 a.m. after an overnight fast from 8:00 p.m., with water permitted throughout. Participants will wear a continuous glucose monitor (CGM) during both trial days. Baseline measurements of blood pressure, heart rate, and oral body temperature will be recorded, and food logs reviewed. Following the condition session, a sedentary recovery period will occur until 9:45 a.m., with repeated physiological measurements. Final measurements of blood pressure, heart rate, and oral body temperature will be collected prior to a standardized breakfast provided from 9:45 to 10:10 a.m. Participants will depart thereafter by car or public transportation and remain sedentary for the remainder of the day. Meals for the rest of the day, i.e., breakfast, lunch, dinner, and a bedtime snack, will be provided and identical across trial days. Participants will fast again from 9:00 p.m. until 9:00 a.m. the following morning.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- Randomized controlled trial (pilot study)
| Arm | Type | Receives |
|---|---|---|
| Sauna | Experimental | Other: Infrared sauna sessionInfrared sauna session |
| Resting control | Placebo comparator | Other: Resting conditionSeated resting session |
Who may qualify
- Ages
- 30 to 55 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Are 30-55 years old
- Have a body mass index of ≥ 27 kg/m2
- Have a waist size >102 cm (men) or >88 cm (women)
- Have access to transportation for the 2 experimental visits (e.g., car, public transit, or drop-off).
- Are cleared for participation based on the Physical Activity Readiness Questionnaire (PAR-Q+).
Key exclusion criteria (5 listed)
- Take medications that affect blood sugar
- Exercise intensely 2+ times/week
- Have diabetes, heart issues, low blood sugar or pressure
- Are pregnant
- Regularly use saunas or other heat therapy 1+ times/week
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Infrared sauna sessionInfrared sauna session (approximately 165°F; two 20-minute sessions separated by a 5-minute rest outside the sauna) | Other | Sauna |
| Resting conditionSeated resting session (45 minutes outside the sauna) | Other | Resting control |
Primary outcome
Incremental 2-hour postprandial glucose area under the curve (Breakfast)
Time frame: 2 hours
2-hour postprandial incremental AUC of CGM glucose above baseline, measured after the standardized breakfast consumed 45 minutes following the sauna or resting (control) session.
11 secondary outcomes
2-hour postprandial glucose area under the curve (Breakfast)
Time frame: 2 hours
Incremental 2-hour postprandial glucose area under the curve (Lunch)
Time frame: 2 hours
Incremental 2-hour postprandial glucose area under the curve (Dinner)
Time frame: 2 hours
Incremental 2-hour postprandial glucose area under the curve (Bedtime snack)
Time frame: 2 hours
Average incremental 2-hour postprandial glucose area under the curve (4 meals)
Time frame: 2 hours
Time below range
Time frame: 24 hours
Time above range
Time frame: 24 hours
Time in range
Time frame: 24 hours
Session-induced delta glucose
Time frame: 45 minutes
Fasting glucose
Time frame: 15 minutes
Daily mean glucose
Time frame: 24 hours
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Apr 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Etienne Myette-Cote principal investigator
University of Prince Edward Island
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Infrared sauna session and Resting condition in people with Obesity & Overweight, run by University of Prince Edward Island at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 9 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Etienne Myette-Cote, PhD (9025660756, emyette-cote@upei.ca), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Incremental 2-hour postprandial glucose area under the curve (Breakfast) (time frame: 2 hours). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Apr 2026.