Cancer SurvivorshipNCT07528963
KanSurvive 2.0: Testing Enhanced Models of Cancer Survivorship Care for Rural Cancer Survivors in Primary Care Practice
A study testing KanSurvive telementoring and education, Practice facilitation for quality improvement and Obesity management toolkit in people with Cancer Survivorship and Primary Care, run by University of Kansas Medical Center at 1 site in United States.
Trial summary
Rural cancer survivors experience a higher risk of negative health outcomes and require coordinated care to address the many effects of cancer and its treatment. Primary care providers recognize the importance of providing high-quality, evidence-based survivorship care and are well-positioned to meet survivor needs… Read more about this study
- Who is it for?
- Ages 18 to 75 yearsHealthy volunteers can take part
- Conditions the study is for
- Cancer Survivorship, Primary Care
- What is being tested?
- KanSurvive telementoring and education, Practice facilitation for quality improvement and Obesity management toolkit
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 16 participants
- Where
- 1 siteUnited States
- Study dates
- 30 Jun 2025to 30 Jun 2029
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 75 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Rural primary care practice (PCP) located within rural urban continuum codes (RUCC) 4-9 in Kansas
- PCPs must have multiple providers
- PCPs must have at least on medical assistant
- PCPs must have an employed medical scribe or be willing to consider employing a medical scribe using study compensation and practice revenue
- Cancer survivor data is eligible for extraction if the patient is a breast, prostate, lung, and/or colorectal cancer survivor and considered to have a "reasonable likelihood" of 24-month survival by a practice provider.
Who cannot join
- PCPs not located within RUCC 4-9 in Kansas
- PCPs without multiple providers
- PCPs without a medical assistant
- PCPs without a medical scribe or unwilling to consider employing one
- Cancer survivorship data is ineligible for extraction is the patient is <18 years of age or >75 years of age, is currently receiving hospice services, or has a history of cancer other than breast, prostate, lung, or colorectal.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site
University of Kansas Medical Center
Kansas City, Kansas, 66160
About this study
Rural cancer survivors experience a higher risk of negative health outcomes and require coordinated care to address the many effects of cancer and its treatment. Primary care providers recognize the importance of providing high-quality, evidence-based survivorship care and are well-positioned to meet survivor needs, however, these needs are often unmet due to limitations in knowledge, lack of resources, and administrative demands. Practical strategies are needed to help PCPs improve cancer survivorship care, and this proposal will test implementation strategies to optimize the adoption of evidence-based practices for cancer survivorship care in rural primary care settings.
Read the detailed description
Cancer survivors require long-term and coordinated care to address the physical, emotional, and psychosocial effects of cancer and its treatment. Rural cancer survivors are disproportionately affected by chronic illness and face a higher risk of negative health outcomes. Primary care providers (PCPs) recognize the importance of delivering evidence-based practice (EBP) cancer survivorship care and are well-positioned to provide comprehensive and coordinated care, however, the needs of cancer survivors are frequently unmet, and providers describe limitations in knowledge of risk-based surveillance, long-term effects of cancer treatment and their management, inadequate resources, and growing administrative demands as barriers to improving survivorship care. The overall goal of this project is to test the effectiveness of pragmatic strategies to promote high quality, evidence-based guideline concordant care for rural adult cancer survivors in primary care practice and utilizing tools from implementation science to gain a better understanding of the decision making and actions taken that facilitate or hinder implementation across multiple healthcare systems. To achieve this objective, we propose a three-arm cluster-randomized, multi-level intervention to provide education, tele-mentoring, and whether 1) virtual scribes filling the role as trained medical assistants, 2) a team-based approach, 3) or usual care produces more guideline concordant cancer survivorship care. The primary outcome is provider adherence to EBP cancer survivorship guidelines as measured using a previously developed composite scoring system that compares electronic health record (EHR) documented activity to National Comprehensive Cancer Network guidelines. The secondary outcome is to assess intervention sustainability of arm 1 and 2 activities at 12 and 24-months post implementation; measured as a function of virtual scribe or team-based actions to promote prior cancer diagnoses coding (ICD-10), use of EHR tools and health maintenance order sets and annual ordering of appropriate screenings for cancer survivors. Prior to implementation, formative evaluations will assess current systems of care and practice-level barriers and facilitators for the delivery of EBP cancer survivorship care and inform modifications to implementation strategies. Guided by the Normalization Process Theory, we will examine agentic factors (e.g., actions taken/decisions made by the practice) to modify modes of care management and delivery. The RE-AIM evaluation framework will be used to explore potential population-level impact and generalizability of the intervention in real-world clinical settings. The study will be conducted in 16 rural primary care practices in Kansas and was intentionally designed to bring care delivery changes into resource-limited practices and health systems. Results will add new evidence by informing pragmatic strategies to facilitate the adoption and delivery of EBP cancer survivorship in rural primary care.
- Conditions
- Cancer Survivorship, Primary Care
- Being tested
- KanSurvive telementoring and education, Practice facilitation for quality improvement, Obesity management toolkit, Survivorship Care Manual, Virtual scribe services
- Keywords
- cancer survivorship, primary care practice
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
KanSurvive telementoring and educationOther
Telementoring, education, and case-based learning covering evidence-based practice guidelines for breast, colorectal, lung, and prostate cancer survivorship.
Practice facilitation for quality improvementOther
Practice facilitation will be delivered to assist with quality improvement efforts using monthly Plan Do Study Act (PDSA) cycles.
Obesity management toolkitOther
The Enhanced Usual Care arm will receive a short, virtual training and toolkit on the management of obesity in primary care practice and how it relates to cancer survivorship.
Survivorship Care ManualOther
Printed and digital manuals will be distributed to each participating primary care practice to share with the cancer survivors they see in their clinic. The manual guides patients on how to engage more effectively with their PCP and oncology care team and reviews recommended follow-up, within a format of a "service manual" and written in lay language.
Virtual scribe servicesOther
Participating practices who opt-in to receive virtual scribe services.
| Study group | Role | What they receive |
|---|---|---|
| Virtual Scribe Medical Assistant | Active comparator | Virtual scribe medical assistants will engage in KanSurvive 2.0 Project ECHO education assist with clinical documentation, identifying cancer survivors, and scrubbing electronic health records to identify care gaps and opportunities for quality improvement with practice facilitation. Receives: Other: KanSurvive telementoring and education; Other: Practice facilitation for quality improvement; Other: Survivorship Care Manual; Other: Virtual scribe services |
| Team Based Care | Active comparator | Rural primary care practice teams will assist with clinical documentation, identifying cancer survivors, and reviewing electronic health records to identify care gaps and opportunities for quality improvement with practice facilitation. Receives: Other: KanSurvive telementoring and education; Other: Practice facilitation for quality improvement; Other: Survivorship Care Manual |
| Enhanced Usual Care | Placebo comparator | This attention control arm will engage in KanSurvive 2.0 Project ECHO education and receive an obesity management toolkit. Receives: Other: KanSurvive telementoring and education; Other: Obesity management toolkit; Other: Survivorship Care Manual |
What is being measured
The primary outcome is the main question the study is designed to answer.
Provider Adherence to Cancer Survivorship Guidelines Measured by EHR-Based Composite Adherence Score
The primary outcome is provider adherence to evidence-based cancer survivorship guidelines, measured using a composite score derived from electronic health record (EHR) data abstraction. The composite score assesses concordance between documented care and National Comprehensive Cancer Network (NCCN) survivorship guidelines across multiple domains (e.g., tumor surveillance, distress screening, BMI assessment, tobacco use screening, family history of cancer documentation, osteoporosis screening, and hereditary cancer risk assessment). Scores are calculated based on the proportion of eligible guideline-concordant care processes completed for each patient and aggregated at the clinic level.
Measured: Assessed at baseline, 6, 12, and 24 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Apr 2026
- Study start30 Jun 2025
- Primary completion1 Aug 2028 (estimated)
- Study completion30 Jun 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Cancer SurvivorshipStudies of the same condition, open and under way.
- More trials run by University of Kansas Medical CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- 8 rural primary care practices will be randomized to the Virtual Scribe Medical Assistant arm, 4 rural primary care practices will be randomized to the Team-Based Care arm, and 4 rural primary care practices will be randomized to the Enhanced Usual Care control arm.
- Masking
- None (open label)
- Enrolment
- 16 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Kansas Medical Center
- Sponsor type
- University, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Responsible party
- Sponsor
- Investigators
- Allen K Greiner, MD, MPH, Principal investigator, University of Kansas Medical Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07528963
- Sponsor's protocol ID
- STUDY00160108
- Other IDs
- U01CA290664
- Status last verified
- Jun 2026
- First submitted
- 15 Apr 2025
- Last updated
- 18 Jun 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Research resources generated within this project will be explicitly developed in an effort to improve cancer survivorship outcomes in rural primary care practice. We will develop a strategic plan with the KU Cancer Center and NCI to widely disseminate any product, intellectual property, or data to promote scientific activity and health promotion work that will be of assistance to similar patient populations. As such, we will work to fully share these materials and items with qualified individuals across the greater scientific community and with rural practices, providers and community members. All program materials and data generated within the overall study will be shared to the fullest extent possible. De-identified data from this project will be preserved and shared in a public repository to validate and replicate research findings described in the Aims.
Study at a glance
From the registry record, last updated by the sponsor on 18 Jun 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- KanSurvive 2.0: Testing Enhanced Models of Cancer Survivorship Care for Rural Cancer Survivors in Primary Care Practice
- ClinicalTrials.gov ID
- NCT07528963
- Acronym / sponsor ID
- STUDY00160108
- Conditions
- Cancer Survivorship, Primary Care
- Keywords
- cancer survivorship, primary care practice
- Study type
- Interventional
- Recruitment status
- Enrolling by invitation
- Enrolment
- 16 participants (estimated)
- Lead sponsor
- University of Kansas Medical CenterUniversity, hospital or other
- Collaborators
- National Cancer Institute (NCI)
- Study start
- 30 Jun 2025 (actual)
- Primary completion
- 1 Aug 2028 (estimated)
- Study completion
- 30 Jun 2029 (estimated)
- First posted
- 14 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Rural cancer survivors experience a higher risk of negative health outcomes and require coordinated care to address the many effects of cancer and its treatment. Primary care providers recognize the importance of providing high-quality, evidence-based survivorship care and are well-positioned to meet survivor needs, however, these needs are often unmet due to limitations in knowledge, lack of resources, and administrative demands. Practical strategies are needed to help PCPs improve cancer survivorship care, and this proposal will test implementation strategies to optimize the adoption of evidence-based practices for cancer survivorship care in rural primary care settings.
Detailed description
Cancer survivors require long-term and coordinated care to address the physical, emotional, and psychosocial effects of cancer and its treatment. Rural cancer survivors are disproportionately affected by chronic illness and face a higher risk of negative health outcomes. Primary care providers (PCPs) recognize the importance of delivering evidence-based practice (EBP) cancer survivorship care and are well-positioned to provide comprehensive and coordinated care, however, the needs of cancer survivors are frequently unmet, and providers describe limitations in knowledge of risk-based surveillance, long-term effects of cancer treatment and their management, inadequate resources, and growing administrative demands as barriers to improving survivorship care. The overall goal of this project is to test the effectiveness of pragmatic strategies to promote high quality, evidence-based guideline concordant care for rural adult cancer survivors in primary care practice and utilizing tools from implementation science to gain a better understanding of the decision making and actions taken that facilitate or hinder implementation across multiple healthcare systems. To achieve this objective, we propose a three-arm cluster-randomized, multi-level intervention to provide education, tele-mentoring, and whether 1) virtual scribes filling the role as trained medical assistants, 2) a team-based approach, 3) or usual care produces more guideline concordant cancer survivorship care. The primary outcome is provider adherence to EBP cancer survivorship guidelines as measured using a previously developed composite scoring system that compares electronic health record (EHR) documented activity to National Comprehensive Cancer Network guidelines. The secondary outcome is to assess intervention sustainability of arm 1 and 2 activities at 12 and 24-months post implementation; measured as a function of virtual scribe or team-based actions to promote prior cancer diagnoses coding (ICD-10), use of EHR tools and health maintenance order sets and annual ordering of appropriate screenings for cancer survivors. Prior to implementation, formative evaluations will assess current systems of care and practice-level barriers and facilitators for the delivery of EBP cancer survivorship care and inform modifications to implementation strategies. Guided by the Normalization Process Theory, we will examine agentic factors (e.g., actions taken/decisions made by the practice) to modify modes of care management and delivery. The RE-AIM evaluation framework will be used to explore potential population-level impact and generalizability of the intervention in real-world clinical settings. The study will be conducted in 16 rural primary care practices in Kansas and was intentionally designed to bring care delivery changes into resource-limited practices and health systems. Results will add new evidence by informing pragmatic strategies to facilitate the adoption and delivery of EBP cancer survivorship in rural primary care.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
- Model description
- 8 rural primary care practices will be randomized to the Virtual Scribe Medical Assistant arm, 4 rural primary care practices will be randomized to the Team-Based Care arm, and 4 rural primary care practices will be randomized to the Enhanced Usual Care control arm.
| Arm | Type | Receives |
|---|---|---|
| Virtual Scribe Medical Assistant | Active comparator | Other: KanSurvive telementoring and education, Other: Practice facilitation for quality improvement, Other: Survivorship Care Manual, Other: Virtual scribe servicesVirtual scribe medical assistants will engage in KanSurvive 2.0 Project ECHO education assist with clinical documentation, identifying cancer survivors, and scrubbing electronic health records to identify care gaps and opportunities for quality improvement with practice facilitation. |
| Team Based Care | Active comparator | Other: KanSurvive telementoring and education, Other: Practice facilitation for quality improvement, Other: Survivorship Care ManualRural primary care practice teams will assist with clinical documentation, identifying cancer survivors, and reviewing electronic health records to identify care gaps and opportunities for quality improvement with practice facilitation. |
| Enhanced Usual Care | Placebo comparator | Other: KanSurvive telementoring and education, Other: Obesity management toolkit, Other: Survivorship Care ManualThis attention control arm will engage in KanSurvive 2.0 Project ECHO education and receive an obesity management toolkit. |
Who may qualify
- Ages
- 18 to 75 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Rural primary care practice (PCP) located within rural urban continuum codes (RUCC) 4-9 in Kansas
- PCPs must have multiple providers
- PCPs must have at least on medical assistant
- PCPs must have an employed medical scribe or be willing to consider employing a medical scribe using study compensation and practice revenue
- Cancer survivor data is eligible for extraction if the patient is a breast, prostate, lung, and/or colorectal cancer survivor and considered to have a "reasonable likelihood" of 24-month survival by a practice provider.
Key exclusion criteria (5 listed)
- PCPs not located within RUCC 4-9 in Kansas
- PCPs without multiple providers
- PCPs without a medical assistant
- PCPs without a medical scribe or unwilling to consider employing one
- Cancer survivorship data is ineligible for extraction is the patient is <18 years of age or >75 years of age, is currently receiving hospice services, or has a history of cancer other than breast, prostate, lung, or colorectal.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| KanSurvive telementoring and educationTelementoring, education, and case-based learning covering evidence-based practice guidelines for breast, colorectal, lung, and prostate cancer survivorship. | Other | Enhanced Usual Care, Team Based Care, Virtual Scribe Medical Assistant |
| Practice facilitation for quality improvementPractice facilitation will be delivered to assist with quality improvement efforts using monthly Plan Do Study Act (PDSA) cycles. | Other | Team Based Care, Virtual Scribe Medical Assistant |
| Obesity management toolkitThe Enhanced Usual Care arm will receive a short, virtual training and toolkit on the management of obesity in primary care practice and how it relates to cancer survivorship. | Other | Enhanced Usual Care |
| Survivorship Care ManualPrinted and digital manuals will be distributed to each participating primary care practice to share with the cancer survivors they see in their clinic. The manual guides patients on how to engage more effectively with their PCP and oncology care team and reviews recommended follow-up, within a format of a "service manual" and written in lay language. | Other | Enhanced Usual Care, Team Based Care, Virtual Scribe Medical Assistant |
| Virtual scribe servicesParticipating practices who opt-in to receive virtual scribe services. | Other | Virtual Scribe Medical Assistant |
Primary outcome
Provider Adherence to Cancer Survivorship Guidelines Measured by EHR-Based Composite Adherence Score
Time frame: Assessed at baseline, 6, 12, and 24 months
The primary outcome is provider adherence to evidence-based cancer survivorship guidelines, measured using a composite score derived from electronic health record (EHR) data abstraction. The composite score assesses concordance between documented care and National Comprehensive Cancer Network (NCCN) survivorship guidelines across multiple domains (e.g., tumor surveillance, distress screening, BMI assessment, tobacco use screening, family history of cancer documentation, osteoporosis screening, and hereditary cancer risk assessment). Scores are calculated based on the proportion of eligible guideline-concordant care processes completed for each patient and aggregated at the clinic level.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Jun 2026.
- Individual participant dataSharing planned: Yes. Research resources generated within this project will be explicitly developed in an effort to improve cancer survivorship outcomes in rural primary care practice. We will develop a strategic plan with the KU Cancer Center and NCI to widely disseminate any product, intellectual property, or data to promote scientific activity and health promotion work that will be of assistance to similar patient populations. As such, we will work to fully share these materials and items with qualified individuals across the greater scientific community and with rural practices, providers and community members. All program materials and data generated within the overall study will be shared to the fullest extent possible. De-identified data from this project will be preserved and shared in a public repository to validate and replicate research findings described in the Aims.
Related trials for Cancer Survivorship
Recruiting
Study of a Support Program for Quality of Life in Chinese Cancer Patients and Survivors
Cancer, Survivorship
Not yet recruiting
Patient-reported Outcomes-driven Supportive Care Navigation Among Hispanic/Latinx Cancer Patients
Cancer
Not yet recruitingPhase 2
Obesity Treatment With Phentermine-Topiramate ER in AYA Surviving Leukemia and Lymphoma
Acute Lymphoblastic Leukemia in Remission, Hodgkin Lymphoma in Remission
RecruitingPhase 1
Study of Preoperative Radiation Therapy in Participants With Resectable Recurrent Abdominal Adrenocortical Carcinoma
Adrenocortical Carcinoma (ACC), Recurrent Adrenocortical Carcinoma (ACC)
Recruiting
Facial Expression Awareness Training to Understand and Recognize Emotions
Survivors of Pediatric Brain Tumors, Pediatric Cancer
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Allen K Greiner, MD, MPH principal investigator
University of Kansas Medical Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing KanSurvive telementoring and education, Practice facilitation for quality improvement and Obesity management toolkit in people with Cancer Survivorship and Primary Care, run by University of Kansas Medical Center at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: enrolling by invitation, as of the sponsor's last update on 18 Jun 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Provider Adherence to Cancer Survivorship Guidelines Measured by EHR-Based Composite Adherence Score (time frame: Assessed at baseline, 6, 12, and 24 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Jun 2026.