Multiple SclerosisMSNCT07538063
Nursing Students' Brain/MS Immersive Three-Dimensional Learning Activity
A study testing The immersive 360-degree educational video and The slideshow (PowerPoint) educational presentation in people with Multiple Sclerosis, run by Hunter College of City University of New York at 2 sites in United States.
Trial summary
This study compared two educational methods. Participants were assigned to participate in a 360-degree experience or a slideshow presentation. The 360-degree video group included a brain and MS program. The comparison group was given a slideshow presentation with the same information. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Multiple Sclerosis
- What is being tested?
- The immersive 360-degree educational video and The slideshow (PowerPoint) educational presentation
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 2 sitesUnited States
- Study dates
- 1 Jul 2020to 31 Dec 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Inclusion Criteria: 1) Adult nursing students ages 18 years and older. 2) All undergraduate nursing students from undergraduate programs at three nursing schools, Hunter College Bellehool of vue School of Nursing, Mount Sinai Phillips School of Nursing, Fairfield University Nursing School.
Exclusion Criteria: 1) Nursing students younger than 18 years old. 2) Nursing students from other nursing schools. 3) Graduate program nursing students.
Trial locations and contacts
2 sites in 1 country.
United States2 sites
Fairfield Univesity Nursing School
Fairfield, Connecticut, 06824
Hunter College
New York, New York, 10006
About this study
Official title: Interactive Educational Methods and Experiences in Nursing Students: A Pilot Study
This study compared two educational methods. Participants were assigned to participate in a 360-degree experience or a slideshow presentation. The 360-degree video group included a brain and MS program. The comparison group was given a slideshow presentation with the same information. Participants viewed the 360-degree program or the slideshow presentation only once. The online-based materials consisted of a demographic form (age, gender, race and ethnicity, and name of school), knowledge questionnaires, and an experiential learning scale. Pre-intervention, participants were asked about demographic information, whether they had previous experience with MS, the science classes they completed in high school and college, and their knowledge of the human brain and MS pathophysiology. At both pre- and post-intervention, participants completed the Multiple Sclerosis Magnetic Resonance Imaging Knowledge Questionnaire (MSMRIKQ) and the Multiple Sclerosis Knowledge Questionnaire (MSKQ). At post-intervention, participants completed a lesson experiential questionnaire about their experience viewing either the 360-degree video or the slideshow presentation. Permission to use the three instruments was obtained from their respective copyright holders.
Read the detailed description
This quasi-experimental study assigned participants to a 360-degree video or a slideshow presentation. Outcomes assessed using the MS Knowledge Questionnaire (MSKQ), the MS Magnetic Resonance Imaging Knowledge Questionnaire (MSMRIKQ), and a post-lesson experiential questionnaire. The theory of multimedia learning and interest theory guided this study in predicting learning outcomes. The objective of this study was to design and analyze the differences and/or similarities between two intervention programs based on two different teaching methods: a 360-degree video presentation versus a slideshow presentation. Participants were assigned to participate in a 360-degree experience or a slideshow presentation. The educational content of both programs consisted of lessons on how the brain and MS interact and interrelate via neurological network. The immersive activity, 360-degree group, included a virtual brain and MS program displayed on an interactive computer screen interface. The 360-degree video allowed learners to manipulate the viewing angle of the video to look around the environment. A 360-degree video on the brain and the pathophysiology of MS displayed on an e-learning platform enabled the students to self-learn through a procedure simulation with real time feedback. The slideshow presentation included 12 slides about the brain and MS with content identical to the content of the 360-degree program. Both programs took approximately 10-15 minutes for each student to complete. The Instruments used in this study included: the MSMRIKQ, the MSKQ and a learning experience tool. A systematic convenience sampling method was used based on the students cohorts databases of the nursing schools. The main analyses were general linear regression models testing the effects of group membership, along with age, sex, and whether a participant reported previous exposure to MS. One model was run for each of the three outcomes: total scores for feelings about the program, general MSKQ, and MSMRIKQ scores. All variables were standardized or coded as dummy (0/1) variables for these analyses.
- Conditions
- Multiple Sclerosis
- Being tested
- The immersive 360-degree educational video, The slideshow (PowerPoint) educational presentation
- Keywords
- Multiple Sclerosis, Interactive Educational Methods, Learning Experience, Nursing Students
- Medical subject headings
- Multiple Sclerosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
The immersive 360-degree educational videoOther
The immersive activity, 360-degree group, included a virtual brain and MS program displayed on an interactive computer screen interface. The 360-degree video allowed learners to manipulate the viewing angle of the video to look around the environment. A 360-degree video on the brain and the pathophysiology of MS displayed on an e-learning platform enabled the students to self-learn through a procedure simulation with real time feedback.
The slideshow (PowerPoint) educational presentationOther
The slideshow presentation included 12 slides about the brain and MS with content identical to the content of the 360-degree program. The educational content of the PowerPoint slideshow presentation consisted of lessons on how the brain and MS interact and interrelate via neurological network.
| Study group | Role | What they receive |
|---|---|---|
| Intervention group - 360-degree educational video | Experimental | The 360-degree video group included a brain and MS program. The immersive activity 360-degree group, included a virtual brain and MS program displayed on an interactive computer screen interface. The 360-degree video allowed learners to manipulate the viewing angle of the video to look around the environment. A 360-degree video on the brain and the pathophysiology of MS displayed on an e-learning platform enabled the students to self-learn through a procedure simulation with real time feedback. Receives: Other: The immersive 360-degree educational video |
| The slideshow presentation group | Active comparator | The slideshow presentation group viewed 12 slides about the brain and MS with content identical to the content of the 360-degree program. The educational content consisted of lessons on how the brain and MS interact and interrelate via neurological network. Receives: Other: The slideshow (PowerPoint) educational presentation |
What is being measured
The primary outcome is the main question the study is designed to answer.
Learning effectiveness of immersive 360-degree video versus a slideshow presentation
The learning effectiveness was evaluated by two instruments. Outcomes assessed using the MS Knowledge Questionnaire(MSKQ), the MS Magnetic Resonance Imaging Knowledge Questionnaire(MSMRIKQ). The MSMRIKQ is a 20-item questionnaire16 that assesses knowledge about MS and MRI. Face validity was established on all MSMRIKQ items.24 The Kuder-Richardson 20 (KR-20) reliability estimate for the entire scale was 0.58. The split-half reliability with Spearman-Brown correction for the total scale was 0.60.
The MSKQ measures basic knowledge of various MS information domains for both clinical and research uses. The Flesch-Kincaid English reading level is 4.8, indicating low reading difficulty. In creating the MSKQ, Giordano et al. (2009) found that the internal consistency was satisfactory (KR-20 = 0.76), and item-total correlations were above 0.30 for 80% of the items.
Measured: The outcomes assessed immediately after viewing the educational 360 degrees video or the PowerPoint slideshow presentation.
Secondary outcomes (1)
The emotional experience
The emotional experience was evaluated by the post-lesson experiential questionnaire. Feelings about each of the respective programs were measured with a set of 17 ad hoc, Likert-style items (scores from 1 to 7, 1=strongly disagree and 7=strongly agree), including a statement on effort and understanding (e.g., "I used a lot of mental effort in the lesson"), a statement on motivation (e.g., "I felt motivated to understand the material"), 4 statements on subject interest for the subject (e.g., "I am interested in learning more about this subject"), engagement with the lesson (e.g., "I felt that the lesson was engaging).26 This questionnaire also included 6 statements about affect during the lesson (e.g. "I felt happy during the lesson"). Some items were positively worded and others negatively worded; negatively phrased items were reverse-coded prior to analysis to ensure consistent interpretation of composite scores. The post-intervention also had an open-ended question for comments.
Measured: The emotional experience was completed immediately after the intervention.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Apr 2026
- Study start1 Jul 2020
- Primary completion31 Dec 2024
- Study completion31 Dec 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Multiple SclerosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Model description
- This is a longitudian quasi-experimental educational study. This study assigned participants to a 360-degree educational video or a slideshow presentation about the brain and multiple sclerosis to undergraduate students from three universities, Hunter College Nursing School, Mount Sinai Phillips School of Nursing, and Fairfield University. Outcomes assessed using the MS Knowledge Questionnaire (MSKQ), the MS Magnetic Resonance Imaging Knowledge Questionnaire( MSMRIKQ), and a post-lesson experiential questionnaire. The theory of multimedia learning and interest theory guided this study in predicting learning outcomes.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 50 participants (actual)
Sponsor and investigators
- Lead sponsor
- Hunter College of City University of New York
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Aliza Bitton Ben-Zacharia, Hunter College of City University of New York
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07538063
- Sponsor's protocol ID
- 2020-0377
- Acronym
- MS
- Status last verified
- Apr 2026
- First submitted
- 12 Apr 2026
- Last updated
- 20 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Data plan and data collection including instruments will be shared with others.
Study at a glance
From the registry record, last updated by the sponsor on 20 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Interactive Educational Methods and Experiences in Nursing Students: A Pilot Study
- ClinicalTrials.gov ID
- NCT07538063
- Acronym / sponsor ID
- MS / 2020-0377
- Conditions
- Multiple Sclerosis
- Keywords
- Multiple Sclerosis, Interactive Educational Methods, Learning Experience, Nursing Students
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 50 participants (actual)
- Lead sponsor
- Hunter College of City University of New YorkUniversity, hospital or other
- Study start
- 1 Jul 2020 (actual)
- Primary completion
- 31 Dec 2024 (actual)
- Study completion
- 31 Dec 2026 (estimated)
- First posted
- 20 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study compared two educational methods. Participants were assigned to participate in a 360-degree experience or a slideshow presentation. The 360-degree video group included a brain and MS program. The comparison group was given a slideshow presentation with the same information. Participants viewed the 360-degree program or the slideshow presentation only once. The online-based materials consisted of a demographic form (age, gender, race and ethnicity, and name of school), knowledge questionnaires, and an experiential learning scale. Pre-intervention, participants were asked about demographic information, whether they had previous experience with MS, the science classes they completed in high school and college, and their knowledge of the human brain and MS pathophysiology. At both pre- and post-intervention, participants completed the Multiple Sclerosis Magnetic Resonance Imaging Knowledge Questionnaire (MSMRIKQ) and the Multiple Sclerosis Knowledge Questionnaire (MSKQ). At post-intervention, participants completed a lesson experiential questionnaire about their experience viewing either the 360-degree video or the slideshow presentation. Permission to use the three instruments was obtained from their respective copyright holders.
Detailed description
This quasi-experimental study assigned participants to a 360-degree video or a slideshow presentation. Outcomes assessed using the MS Knowledge Questionnaire (MSKQ), the MS Magnetic Resonance Imaging Knowledge Questionnaire (MSMRIKQ), and a post-lesson experiential questionnaire. The theory of multimedia learning and interest theory guided this study in predicting learning outcomes. The objective of this study was to design and analyze the differences and/or similarities between two intervention programs based on two different teaching methods: a 360-degree video presentation versus a slideshow presentation. Participants were assigned to participate in a 360-degree experience or a slideshow presentation. The educational content of both programs consisted of lessons on how the brain and MS interact and interrelate via neurological network. The immersive activity, 360-degree group, included a virtual brain and MS program displayed on an interactive computer screen interface. The 360-degree video allowed learners to manipulate the viewing angle of the video to look around the environment. A 360-degree video on the brain and the pathophysiology of MS displayed on an e-learning platform enabled the students to self-learn through a procedure simulation with real time feedback. The slideshow presentation included 12 slides about the brain and MS with content identical to the content of the 360-degree program. Both programs took approximately 10-15 minutes for each student to complete. The Instruments used in this study included: the MSMRIKQ, the MSKQ and a learning experience tool. A systematic convenience sampling method was used based on the students cohorts databases of the nursing schools. The main analyses were general linear regression models testing the effects of group membership, along with age, sex, and whether a participant reported previous exposure to MS. One model was run for each of the three outcomes: total scores for feelings about the program, general MSKQ, and MSMRIKQ scores. All variables were standardized or coded as dummy (0/1) variables for these analyses.
Study design
- Primary purpose
- Other
- Allocation
- Non-randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- This is a longitudian quasi-experimental educational study. This study assigned participants to a 360-degree educational video or a slideshow presentation about the brain and multiple sclerosis to undergraduate students from three universities, Hunter College Nursing School, Mount Sinai Phillips School of Nursing, and Fairfield University. Outcomes assessed using the MS Knowledge Questionnaire (MSKQ), the MS Magnetic Resonance Imaging Knowledge Questionnaire( MSMRIKQ), and a post-lesson experiential questionnaire. The theory of multimedia learning and interest theory guided this study in predicting learning outcomes.
| Arm | Type | Receives |
|---|---|---|
| Intervention group - 360-degree educational video | Experimental | Other: The immersive 360-degree educational videoThe 360-degree video group included a brain and MS program. The immersive activity 360-degree group, included a virtual brain and MS program displayed on an interactive computer screen interface. The 360-degree video allowed learners to manipulate the viewing angle of the video to look around the environment. A 360-degree video on the brain and the pathophysiology of MS displayed on an e-learning platform enabled the students to self-learn through a procedure simulation with real time feedback. |
| The slideshow presentation group | Active comparator | Other: The slideshow (PowerPoint) educational presentationThe slideshow presentation group viewed 12 slides about the brain and MS with content identical to the content of the 360-degree program. The educational content consisted of lessons on how the brain and MS interact and interrelate via neurological network. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| The immersive 360-degree educational videoThe immersive activity, 360-degree group, included a virtual brain and MS program displayed on an interactive computer screen interface. The 360-degree video allowed learners to manipulate the viewing angle of the video to look around the environment. A 360-degree video on the brain and the pathophysiology of MS displayed on an e-learning platform enabled the students to self-learn through a procedure simulation with real time feedback. | Other | Intervention group - 360-degree educational video |
| The slideshow (PowerPoint) educational presentationThe slideshow presentation included 12 slides about the brain and MS with content identical to the content of the 360-degree program. The educational content of the PowerPoint slideshow presentation consisted of lessons on how the brain and MS interact and interrelate via neurological network. | Other | The slideshow presentation group |
Primary outcome
Learning effectiveness of immersive 360-degree video versus a slideshow presentation
Time frame: The outcomes assessed immediately after viewing the educational 360 degrees video or the PowerPoint slideshow presentation.
The learning effectiveness was evaluated by two instruments. Outcomes assessed using the MS Knowledge Questionnaire(MSKQ), the MS Magnetic Resonance Imaging Knowledge Questionnaire(MSMRIKQ). The MSMRIKQ is a 20-item questionnaire16 that assesses knowledge about MS and MRI. Face validity was established on all MSMRIKQ items.24 The Kuder-Richardson 20 (KR-20) reliability estimate for the entire scale was 0.58. The split-half reliability with Spearman-Brown correction for the total scale was 0.60. The MSKQ measures basic knowledge of various MS information domains for both clinical and research uses. The Flesch-Kincaid English reading level is 4.8, indicating low reading difficulty. In creating the MSKQ, Giordano et al. (2009) found that the internal consistency was satisfactory (KR-20 = 0.76), and item-total correlations were above 0.30 for 80% of the items.
1 secondary outcome
The emotional experience
Time frame: The emotional experience was completed immediately after the intervention.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 Apr 2026.
- Poster presentation at ENRS 2025Link provided by the sponsor.
- Individual participant dataSharing planned: Yes. Data plan and data collection including instruments will be shared with others.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing The immersive 360-degree educational video and The slideshow (PowerPoint) educational presentation in people with Multiple Sclerosis, run by Hunter College of City University of New York at 2 sites in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 20 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Learning effectiveness of immersive 360-degree video versus a slideshow presentation (time frame: The outcomes assessed immediately after viewing the educational 360 degrees video or the PowerPoint slideshow presentation.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 Apr 2026.