Multiple SclerosisMSNCT07544303
Fatigue and Mental Well-Being in MS Patients(Multiple Sclerosis)
A study testing Quran recital in people with Multiple Sclerosis, run by Artvin Coruh University at 1 site in Turkey (Türkiye).
Trial summary
This study will be conducted to evaluate the effects of Quran recital on fatigue and mental well-being in patients with multiple sclerosis. Hypotheses: 1. Quran recital reduces fatigue in MS patients. 2. Quran recital increases mental well-being in MS patients. Read more about this study
- Who is it for?
- Ages 18 to 80 years
- Conditions the study is for
- Multiple Sclerosis
- What is being tested?
- Quran recital
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 52 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 9 Sep 2025to 15 May 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Having been diagnosed with Multiple Sclerosis at least 6 months ago
- Being between the ages of 18-80
- Agreeing to participate in the research
- Not having any obstacles to wearing headphones
- Not having any hearing problems
Who cannot join
- Those with major psychiatric disorders
- Those with any obstacle to communication
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Van Yüzüncü Yıl University Dursun Odabaş Medical Center
Van, 65200
Yavuz Üren, Asst. Prof
About this study
Official title: Evaluation of the Effect of Quran Recitation on Fatigue and Mental Well-Being in MS Patients: A Randomized Controlled Trial
This study will be conducted to evaluate the effects of Quran recital on fatigue and mental well-being in patients with multiple sclerosis.
Hypotheses:
- Quran recital reduces fatigue in MS patients.
- Quran recital increases mental well-being in MS patients. The patients will be called by the researcher to ask whether they continue this practice. The control group will continue their routine treatment and care and no additional intervention will be applied. The final test measurements will be made by meeting with the patients in the hospital at the end of the 4th week.
Read the detailed description
50 patients who meet the inclusion criteria and voluntarily agree to participate in the study will be determined. These patients will be informed about the study and their consent will be obtained. These patients will then be randomized into the Quran recital group and the control group. Personal and contact information of the patients will be recorded and pre-test forms will be applied. The Quran recital group will be asked to listen to the Quran for half an hour with an mp3 player given to them 3 days a week (Monday-Wednesday-Friday) between 21:00-22:00 and this practice will be continued for 4 weeks. The patients will be called by the researcher to ask whether they continue this practice. The control group will continue their routine treatment and care and no additional intervention will be applied. The final test measurements will be made by meeting with the patients in the hospital at the end of the 4th week.
- Conditions
- Multiple Sclerosis
- Being tested
- Quran recital
- Keywords
- multiple Sclerosis,, Quran,, fatigue,, mental well-being,
- Medical subject headings
- Multiple Sclerosis, Fatigue, Psychological Well-Being
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Quran recitalBehavioural
The Quran recital group will be asked to listen to the Quran (Surah Yasin) for half an hour with an mp3 player given to them between 21.00-22.00 three days a week (Monday-Wednesday-Friday) and they will be asked to continue this practice for 4 weeks.
| Study group | Role | What they receive |
|---|---|---|
| Experimental group | Experimental | The Quran recital group will be asked to listen to the Quran (Surah Yasin) for half an hour with an mp3 player given to them between 21:00-22:00 3 days a week (Monday-Wednesday-Friday) and they will be asked to continue this practice for 4 weeks. The patients will be called by the researcher to ask whether they continue this practice. The final test measurements will be made at the end of the 4th week by interviewing the patients at the hospital. Receives: Behavioral: Quran recital |
| Control group | No intervention | Personal and contact information about the patients will be recorded and pre-test forms will be applied. The control group will continue their routine treatment and care and no additional intervention will be applied. Post-test measurements will be made by meeting with the patients at the hospital at the end of the 4th week. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Fatigue Impact
The Fatigue Impact Scale (FIS)
Measured: 1 mount
Secondary outcomes (1)
Fatigue Severity Warwick-Edinburgh Mental Well-Being Scale
The Fatigue Severity Scale (FSS)
Measured: 1 mount
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 Apr 2026
- Study start9 Sep 2025
- Primary completion15 May 2026 (estimated)
- Study completion15 May 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Multiple SclerosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 52 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Artvin Coruh University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Sevgi DEMIR CAM, Artvin Coruh University
- Investigators
- Sevgi Demir Cam, Asst. Prof, Study chair, Artvin Çoruh University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07544303
- Sponsor's protocol ID
- MS-Kuran
- Acronym
- MS
- Status last verified
- Apr 2026
- First submitted
- 4 Jul 2025
- Last updated
- 22 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of the Effect of Quran Recitation on Fatigue and Mental Well-Being in MS Patients: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07544303
- Acronym / sponsor ID
- MS / MS-Kuran
- Conditions
- Multiple Sclerosis
- Keywords
- multiple Sclerosis,, Quran,, fatigue,, mental well-being,
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 52 participants (estimated)
- Lead sponsor
- Artvin Coruh UniversityUniversity, hospital or other
- Study start
- 9 Sep 2025 (actual)
- Primary completion
- 15 May 2026 (estimated)
- Study completion
- 15 May 2026 (estimated)
- First posted
- 22 Apr 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will be conducted to evaluate the effects of Quran recital on fatigue and mental well-being in patients with multiple sclerosis.
Hypotheses:
- Quran recital reduces fatigue in MS patients.
- Quran recital increases mental well-being in MS patients. The patients will be called by the researcher to ask whether they continue this practice. The control group will continue their routine treatment and care and no additional intervention will be applied. The final test measurements will be made by meeting with the patients in the hospital at the end of the 4th week.
Detailed description
50 patients who meet the inclusion criteria and voluntarily agree to participate in the study will be determined. These patients will be informed about the study and their consent will be obtained. These patients will then be randomized into the Quran recital group and the control group. Personal and contact information of the patients will be recorded and pre-test forms will be applied. The Quran recital group will be asked to listen to the Quran for half an hour with an mp3 player given to them 3 days a week (Monday-Wednesday-Friday) between 21:00-22:00 and this practice will be continued for 4 weeks. The patients will be called by the researcher to ask whether they continue this practice. The control group will continue their routine treatment and care and no additional intervention will be applied. The final test measurements will be made by meeting with the patients in the hospital at the end of the 4th week.
Study design
- Primary purpose
- Supportive care
- Allocation
- Randomised
- Intervention model
- Single group
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Experimental group | Experimental | Behavioral: Quran recitalThe Quran recital group will be asked to listen to the Quran (Surah Yasin) for half an hour with an mp3 player given to them between 21:00-22:00 3 days a week (Monday-Wednesday-Friday) and they will be asked to continue this practice for 4 weeks. The patients will be called by the researcher to ask whether they continue this practice. The final test measurements will be made at the end of the 4th week by interviewing the patients at the hospital. |
| Control group | No intervention | –Personal and contact information about the patients will be recorded and pre-test forms will be applied. The control group will continue their routine treatment and care and no additional intervention will be applied. Post-test measurements will be made by meeting with the patients at the hospital at the end of the 4th week. |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Having been diagnosed with Multiple Sclerosis at least 6 months ago
- Being between the ages of 18-80
- Agreeing to participate in the research
- Not having any obstacles to wearing headphones
- Not having any hearing problems
Key exclusion criteria (2 listed)
- Those with major psychiatric disorders
- Those with any obstacle to communication
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Quran recitalThe Quran recital group will be asked to listen to the Quran (Surah Yasin) for half an hour with an mp3 player given to them between 21.00-22.00 three days a week (Monday-Wednesday-Friday) and they will be asked to continue this practice for 4 weeks. | Behavioural | Experimental group |
Primary outcome
Fatigue Impact
Time frame: 1 mount
The Fatigue Impact Scale (FIS)
1 secondary outcome
Fatigue Severity Warwick-Edinburgh Mental Well-Being Scale
Time frame: 1 mount
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Apr 2026.
- Individual participant dataSharing planned: No
Related trials for Multiple Sclerosis
RecruitingPhase 4
Individualised Cryoneurolysis to Treat Pain in the Context of Spasticity in the Upper and Lower Extremities
Centreal Neurological Condition, Acquired Brain Injury (Including Stroke)
Active, not recruiting
Myrosinase Bioactivated Gglucoraphanin for the Treatment of Neurodegenerative Diseases (GRA-MYR-ND)
PARKINSON DISEASE (Disorder), Multiple Sclerosis (MS) - Relapsing-remitting
RecruitingPhase 2
Targeting Agonists of Glucagon-like Peptide-1 Receptor for Multiple Sclerosis
Multiple Sclerosis
Not yet recruitingPhase 1
A Study of Subcutaneously Administered RO7845860 in Participants With Relapsing Multiple Sclerosis
Relapsing Multiple Sclerosis
Recruiting
Virtual Reality Versus Mental Practice On Balance And Gait In Patients With Multiple Sclerosis
Multiple Sclerosis
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Sevgi Demir Cam, Asst. Prof study chair
Artvin Çoruh University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Quran recital in people with Multiple Sclerosis, run by Artvin Coruh University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 22 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact SEVGİ DEMİR ÇAM, Asst. Prof (905073468284, sevgidemir91@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Fatigue Impact (time frame: 1 mount). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Apr 2026; AzTrials last refreshed its copy on 6 Nov 2026.