Open BiteNCT07567105
Stability of Orthodontic Treatment of Anterior Open-bite
An observational study of Open Bite, run by University of Helsinki at 1 site in Finland.
Trial summary
The study aims to explore how an open bite malocclusion affects daily life of an individual, is its orthodontic treatment effective, and what kind of burden of care the treatment has caused. Read more about this study
- Who is it for?
- Any age
- Conditions the study is for
- Open Bite
- How many people
- 80 participants
- Where
- 1 siteFinland
- Study dates
- 1 Dec 2025to 30 Jul 2030
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Volunteers recruited based on diagnosis code
Who may be able to join
- Clinical diagnosis of anterior open bite malocclusion, past or present
Who cannot join
- No malocclusion
- craniofacial genetic anomaly
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Finland1 site, 1 recruiting
- Recruiting
Vantaa and Kerava Wellbeing Services County
Vantaa
Heidi Arponen, heidi.arponen@vakehyva.fi, heidi.arponen@vakehyva.fi
About this study
Official title: Orthodontic Correction of Anterior Open-bite, Treatment Outcome Stability and Impact of Anterior Open Bite Malocclusion
The study aims to explore how an open bite malocclusion affects daily life of an individual, is its orthodontic treatment effective, and what kind of burden of care the treatment has caused.
- Conditions
- Open Bite
- Keywords
- Anterior open bite
- Medical subject headings
- Open Bite
What is being measured
The primary outcome is the main question the study is designed to answer.
Overbite
Vertical overbite
Measured: through study completion, an average of 1 year
Secondary outcomes (3)
Occlusal contacts
Number of occluding teeth
Measured: through study completion, an average of 1 year
Treatment time
Duration of received orthodontic treatment
Measured: Perioperative/Periprocedural
TMD
Temporomandibular joint dysfunction
Measured: through study completion, an average of 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted5 May 2026
- Study start1 Dec 2025
- Primary completion31 Dec 2029 (estimated)
- Study completion30 Jul 2030 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Open BiteStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Cross-sectional
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Helsinki
- Sponsor type
- University, hospital or other
- Collaborators
- Vantaa and Keravan Wellbeing Services County
- Responsible party
- Principal investigator, Heidi Arponen, University of Helsinki
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07567105
- Sponsor's protocol ID
- HUS/7152/2025
- Status last verified
- Apr 2026
- First submitted
- 14 Jan 2026
- Last updated
- 5 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 5 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Orthodontic Correction of Anterior Open-bite, Treatment Outcome Stability and Impact of Anterior Open Bite Malocclusion
- ClinicalTrials.gov ID
- NCT07567105
- Acronym / sponsor ID
- HUS/7152/2025
- Conditions
- Open Bite
- Keywords
- Anterior open bite
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- University of HelsinkiUniversity, hospital or other
- Collaborators
- Vantaa and Keravan Wellbeing Services County
- Study start
- 1 Dec 2025 (actual)
- Primary completion
- 31 Dec 2029 (estimated)
- Study completion
- 30 Jul 2030 (estimated)
- First posted
- 5 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The study aims to explore how an open bite malocclusion affects daily life of an individual, is its orthodontic treatment effective, and what kind of burden of care the treatment has caused.
Study design
- Observational model
- Cohort
- Time perspective
- Cross-sectional
Who may qualify
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Volunteers recruited based on diagnosis code
Key inclusion criteria (1 listed)
- Clinical diagnosis of anterior open bite malocclusion, past or present
Key exclusion criteria (2 listed)
- No malocclusion
- craniofacial genetic anomaly
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Overbite
Time frame: through study completion, an average of 1 year
Vertical overbite
3 secondary outcomes
Occlusal contacts
Time frame: through study completion, an average of 1 year
Treatment time
Time frame: Perioperative/Periprocedural
TMD
Time frame: through study completion, an average of 1 year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 May 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Open Bite, run by University of Helsinki at 1 site in Finland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 5 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Finland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Heidi Arponen, PhD (heidi.arponen@vakehyva.fi, heidi.arponen@vakehyva.fi), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Overbite (time frame: through study completion, an average of 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 May 2026.