Knee OsteoarthritisNCT07568691
Comparing Whole-Body Vibration vs. Balance Board Exercise for Pain, Function, and Quality of Life in Obese Adults With Knee Osteoarthritis
A study testing Stochastic Resonance Therapy-Whole Body Vibration and Balance Board in people with Knee Osteoarthritis and Stochastic Resonance Therapy-Whole Body Vibration, run by Universitas Indonesia at 1 site in Indonesia.
Trial summary
Background: Osteoarthritis (OA) is a joint disease commonly found in the knee. Therapeutic exercise has been known as the most common therapy to treat OA, however, therapy only focuses on reducing symptoms, not on treatment of the disease which help reduce cost and improve long term quality of life. Read more about this study
- Who is it for?
- Ages 45 to 65 years
- Conditions the study is for
- Knee Osteoarthritis, Stochastic Resonance Therapy-Whole Body Vibration, Obesity
- What is being tested?
- Stochastic Resonance Therapy-Whole Body Vibration and Balance Board
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 44 participants
- Where
- 1 siteIndonesia
- Study dates
- 1 Mar 2023to 15 Oct 2023
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- 45-65 years old patient
- VAS score ranged from 4 - 6
- Diagnosed with knee OA KL Grade I - II based on American College of Rheumatology Classification
- Grade I obesity
- Understand Bahasa Indonesia
Who cannot join
- Used assistive devices or can't walk
- Diagnosed with other medical conditions or mentally unstable
- Diagnosed with advanced stage of osteoporosis
- Had history of knee surgery
- Were currently taking analgesic or anti-inflammatory medications
- Pregnant
- Unwilling to participate
Trial locations and contacts
1 site in 1 country.
Indonesia1 site
Universitas Indonesia, Cipto Mangunkusumo General Hospital
Jakarta Pusat, DKI Jakarta, 10430
About this study
Official title: Comparison of the Effectiveness of Balance Training Using Stochastic Resonance Therapy-Whole Body Vibration and Balanced Board in Obese Patients With Knee Osteoarthritis: A Randomized Controlled Trial
Background: Osteoarthritis (OA) is a joint disease commonly found in the knee. Therapeutic exercise has been known as the most common therapy to treat OA, however, therapy only focuses on reducing symptoms, not on treatment of the disease which help reduce cost and improve long term quality of life. Objective: This randomized controlled trial aim was to compare the effectiveness of Stochastic Resonance Therapy-Whole Body Vibration (SRT-WBV) vs. Balance Board (BB) training on knee pain, knee function and quality of life in obese patients with osteoarthritis. Design: Randomized controlled trial. Methods: Forty-four subjects diagnosed with Grade I-II Osteoarthritis Kellgren Lawrence and Grade I obesity were included, randomized to two treatment groups, the SRT-WBV (n=22) or BB (n=22) to complete a series of exercises over eight weeks. Evaluation using the following clinical outcomes: Visual Analog Scale (VAS), Timed Up and Go test (TUG), Single leg stance (SLS) test, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Short Form 12 Health Survey Questions (SF-12).
- Conditions
- Knee Osteoarthritis, Stochastic Resonance Therapy-Whole Body Vibration, Obesity, Balance Board
- Being tested
- Stochastic Resonance Therapy-Whole Body Vibration, Balance Board
- Keywords
- Osteoarthritis, Knee Pain, Stochastic Resonance Therapy-Whole Body Vibration, Balance Board, Therapeutic Exercise
- Medical subject headings
- Osteoarthritis, Knee, Obesity, Osteoarthritis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Stochastic Resonance Therapy-Whole Body VibrationDevice
Also called SRT-WBV
A total of 16 therapeutic exercise sessions were conducted during the intervention where 2 sessions were conducted every week, separated by at least one day. Specifically, subjects assigned to either group, with each session began with standardized warm-up exercises lasting approximately 5-10 minutes, followed by specific therapeutic exercises such as SRT-WBV and Balance Board.
Balance BoardDevice
The balance board intervention used different durations as its intensity, such as 7.5 minutes, 10 minutes, 12.5 minutes, and 15 minutes continuously without resting period. The intensity of exercise was progressively increased every 2 weeks until completion of the program.
| Study group | Role | What they receive |
|---|---|---|
| Stochastic Resonance Therapy-Whole Body Vibration | Active comparator | Subjects assigned to the SRT-WBV group were required to stand on the footboard of the SRT-WBV (SR Therapiesysteme GmbH \& Co. Lifescience KG, Berlin) device with shoulder width stance, and knees bent at 30 degrees, facing forward. The trim settings progressed from weak (45 seconds with 8 repetitions), to mild (55 seconds with 8 repetitions), average (60 seconds with 6 repetitions), and strong (60 seconds with 6 repetitions), with intensity increased at two-week intervals. Each repetition was separated by a resting period that had the same duration as the trim settings (weak: 45 seconds, mild: 55 seconds, average and strong: 60 seconds). Receives: Device: Stochastic Resonance Therapy-Whole Body Vibration |
| Balance Board | Active comparator | Subjects were required to stand on the balance board with knees bent at 30 degrees and both hands placed on the chest with eyes opened. The balance board intervention used different durations as its intensity, such as 7.5 minutes, 10 minutes, 12.5 minutes, and 15 minutes continuously without resting period. The intensity of exercise was progressively increased every 2 weeks until completion of the program. Receives: Device: Balance Board |
What is being measured
The primary outcome is the main question the study is designed to answer.
Knee function (WOMAC Total Score)
Knee function was assessed using the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) questionnaire where pain score, stiffness, and physical function were evaluated on a scale of 0-4, with higher scores indicating worse pain, stiffness, and functional limitations. The questionnaire contains 24 items and the WOMAC Osteoarthritis Index scores were then derived from the sum of the scores for the three subscales It was administered at the beginning and completion of the intervention, as well as every 4 weeks during the intervention.
Measured: 8 weeks
Timed Up and Go Test (Balance)
Balance and mobility will be assessed using the Timed Up and Go Test. The time (in seconds) taken to stand up from a chair, walk 3 meters, turn, return, and sit down will be recorded.
Measured: 8 weeks
Straight Leg Raise Test
Balance/flexibility will be assessed using the Straight Leg Raise test. The maximum angle (in degrees) achieved during leg elevation will be recorded.
Measured: 8 weeks
Knee Pain (VAS Score)
Knee pain will be measured using the Visual Analog Scale ranging from 0 to 10, with higher scores indicating greater pain. Participants will rate their pain at rest while seated.
Measured: 8 weeks
Secondary outcomes (1)
Quality of Life (SF-12 Score)
Quality of life will be assessed using the SF-12. Scores will be calculated according to standard scoring procedures.
Measured: 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted6 May 2026
- Study start1 Mar 2023
- Primary completion30 Sep 2023
- Study completion15 Oct 2023
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Knee OsteoarthritisStudies of the same condition, open and under way.
- More trials run by Universitas IndonesiaThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 44 participants (actual)
Sponsor and investigators
- Lead sponsor
- Universitas Indonesia
- Sponsor type
- University, hospital or other
- Collaborators
- Terramed Physio & Rehab, National Sports Institute Malaysia
- Responsible party
- Principal investigator, Tirza Z Tamin, Universitas Indonesia
- Investigators
- Tirza Z Tamin, MD, Principal investigator, Universitas Indonesia
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07568691
- Sponsor's protocol ID
- SRTKneeOsteoarthritis
- Status last verified
- Apr 2026
- First submitted
- 21 Apr 2026
- Last updated
- 6 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 6 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of the Effectiveness of Balance Training Using Stochastic Resonance Therapy-Whole Body Vibration and Balanced Board in Obese Patients With Knee Osteoarthritis: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT07568691
- Acronym / sponsor ID
- SRTKneeOsteoarthritis
- Conditions
- Knee Osteoarthritis, Stochastic Resonance Therapy-Whole Body Vibration, Obesity, Balance Board
- Keywords
- Osteoarthritis, Knee Pain, Stochastic Resonance Therapy-Whole Body Vibration, Balance Board, Therapeutic Exercise
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 44 participants (actual)
- Lead sponsor
- Universitas IndonesiaUniversity, hospital or other
- Collaborators
- Terramed Physio & Rehab, National Sports Institute Malaysia
- Study start
- 1 Mar 2023 (actual)
- Primary completion
- 30 Sep 2023 (actual)
- Study completion
- 15 Oct 2023 (actual)
- First posted
- 6 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Background: Osteoarthritis (OA) is a joint disease commonly found in the knee. Therapeutic exercise has been known as the most common therapy to treat OA, however, therapy only focuses on reducing symptoms, not on treatment of the disease which help reduce cost and improve long term quality of life. Objective: This randomized controlled trial aim was to compare the effectiveness of Stochastic Resonance Therapy-Whole Body Vibration (SRT-WBV) vs. Balance Board (BB) training on knee pain, knee function and quality of life in obese patients with osteoarthritis. Design: Randomized controlled trial. Methods: Forty-four subjects diagnosed with Grade I-II Osteoarthritis Kellgren Lawrence and Grade I obesity were included, randomized to two treatment groups, the SRT-WBV (n=22) or BB (n=22) to complete a series of exercises over eight weeks. Evaluation using the following clinical outcomes: Visual Analog Scale (VAS), Timed Up and Go test (TUG), Single leg stance (SLS) test, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and Short Form 12 Health Survey Questions (SF-12).
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Stochastic Resonance Therapy-Whole Body Vibration | Active comparator | Device: Stochastic Resonance Therapy-Whole Body VibrationSubjects assigned to the SRT-WBV group were required to stand on the footboard of the SRT-WBV (SR Therapiesysteme GmbH \& Co. Lifescience KG, Berlin) device with shoulder width stance, and knees bent at 30 degrees, facing forward. The trim settings progressed from weak (45 seconds with 8 repetitions), to mild (55 seconds with 8 repetitions), average (60 seconds with 6 repetitions), and strong (60 seconds with 6 repetitions), with intensity increased at two-week intervals. Each repetition was separated by a resting period that had the same duration as the trim settings (weak: 45 seconds, mild: 55 seconds, average and strong: 60 seconds). |
| Balance Board | Active comparator | Device: Balance BoardSubjects were required to stand on the balance board with knees bent at 30 degrees and both hands placed on the chest with eyes opened. The balance board intervention used different durations as its intensity, such as 7.5 minutes, 10 minutes, 12.5 minutes, and 15 minutes continuously without resting period. The intensity of exercise was progressively increased every 2 weeks until completion of the program. |
Who may qualify
- Ages
- 45 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- 45-65 years old patient
- VAS score ranged from 4 - 6
- Diagnosed with knee OA KL Grade I - II based on American College of Rheumatology Classification
- Grade I obesity
- Understand Bahasa Indonesia
Key exclusion criteria (7 listed)
- Used assistive devices or can't walk
- Diagnosed with other medical conditions or mentally unstable
- Diagnosed with advanced stage of osteoporosis
- Had history of knee surgery
- Were currently taking analgesic or anti-inflammatory medications
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Stochastic Resonance Therapy-Whole Body VibrationAlso: SRT-WBVA total of 16 therapeutic exercise sessions were conducted during the intervention where 2 sessions were conducted every week, separated by at least one day. Specifically, subjects assigned to either group, with each session began with standardized warm-up exercises lasting approximately 5-10 minutes, followed by specific therapeutic exercises such as SRT-WBV and Balance Board. | Device | Stochastic Resonance Therapy-Whole Body Vibration |
| Balance BoardThe balance board intervention used different durations as its intensity, such as 7.5 minutes, 10 minutes, 12.5 minutes, and 15 minutes continuously without resting period. The intensity of exercise was progressively increased every 2 weeks until completion of the program. | Device | Balance Board |
Primary outcome
Knee function (WOMAC Total Score)
Time frame: 8 weeks
Knee function was assessed using the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) questionnaire where pain score, stiffness, and physical function were evaluated on a scale of 0-4, with higher scores indicating worse pain, stiffness, and functional limitations. The questionnaire contains 24 items and the WOMAC Osteoarthritis Index scores were then derived from the sum of the scores for the three subscales It was administered at the beginning and completion of the intervention, as well as every 4 weeks during the intervention.
Timed Up and Go Test (Balance)
Time frame: 8 weeks
Balance and mobility will be assessed using the Timed Up and Go Test. The time (in seconds) taken to stand up from a chair, walk 3 meters, turn, return, and sit down will be recorded.
Straight Leg Raise Test
Time frame: 8 weeks
Balance/flexibility will be assessed using the Straight Leg Raise test. The maximum angle (in degrees) achieved during leg elevation will be recorded.
Knee Pain (VAS Score)
Time frame: 8 weeks
Knee pain will be measured using the Visual Analog Scale ranging from 0 to 10, with higher scores indicating greater pain. Participants will rate their pain at rest while seated.
1 secondary outcome
Quality of Life (SF-12 Score)
Time frame: 8 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 May 2026.
- Individual participant dataSharing planned: No
Related trials for Knee Osteoarthritis
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The Feasibility of a Virtual/Home-based OA Treatment Program in Older Adults With OA and Multimorbidity
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Tirza Z Tamin, MD principal investigator
Universitas Indonesia
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Stochastic Resonance Therapy-Whole Body Vibration and Balance Board in people with Knee Osteoarthritis and Stochastic Resonance Therapy-Whole Body Vibration, run by Universitas Indonesia at 1 site in Indonesia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Indonesia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Knee function (WOMAC Total Score) (time frame: 8 weeks). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 May 2026.