Motoric Cognitive Risk SyndromeNCT07572942
Laser-Based Map Tests in Motoric Cognitive Risk Syndrome
An observational study of Motoric Cognitive Risk Syndrome and Cognitive-Motor Interaction, run by Balikesir University at 1 site in Turkey (Türkiye).
Trial summary
This study aims to evaluate the validity and reliability of neuroscience-based visual laser feedback map tests in individuals with Motoric Cognitive Risk Syndrome (MCRS). The developed assessment protocol integrates visuospatial processing, reaction time, and upper extremity motor control within a single task. Read more about this study
- Who is it for?
- Ages 65 years and older
- Conditions the study is for
- Motoric Cognitive Risk Syndrome, Cognitive-Motor Interaction, Sensorimotor Performance
- How many people
- 35 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Apr 2026to 15 Jul 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- No healthy volunteers
- Older adult
Study population: Community-dwelling older adults aged 65 years and above diagnosed with Motoric Cognitive Risk Syndrome will be recruited from the Tazelenme University Coordination Unit in Balıkesir, Turkey. The study population represents individuals at risk of cognitive decline but without diagnosed dementia, enabling the evaluation of early-stage cognitive-motor interaction.
Who may be able to join
- Aged ≥65 years Diagnosis of Motoric Cognitive Risk Syndrome (subjective cognitive complaint + slow gait) Living independently in the community Able to understand and perform test procedures
Who cannot join
- Diagnosed dementia Severe psychiatric disorders Advanced visual impairments (e.g., macular degeneration, severe cataract) Neurological disorders affecting motor control Severe tremor or ataxia interfering with task performance
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Balikesir University
Balıkesir, Bigadiç
Ebru Tekin, +90 266 614 69 11, ebrutekin123@gmail.com
About this study
Official title: Validity and Reliability of Neuroscience-Based Visual Laser Feedback Map Tests in Individuals With Motoric Cognitive Risk Syndrome
This study aims to evaluate the validity and reliability of neuroscience-based visual laser feedback map tests in individuals with Motoric Cognitive Risk Syndrome (MCRS). The developed assessment protocol integrates visuospatial processing, reaction time, and upper extremity motor control within a single task. Construct validity will be examined through correlations with reaction time and proprioception measurements, and test-retest reliability will be assessed to determine measurement consistency.
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Motoric Cognitive Risk Syndrome Group | Community-dwelling older adults aged 65 years and above diagnosed with Motoric Cognitive Risk Syndrome (MCRS) will be included. Participants will undergo neuroscience-based visual-laser feedback map tests along with reaction time and proprioception assessments under standardized conditions. No therapeutic intervention will be applied. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Visual-laser feedback map test performance
Performance parameters including completion time (seconds), reaction time (milliseconds), movement accuracy, and total performance score obtained from the figure-of-eight tracing and directional target tracking tasks.
Measured: Baseline
Secondary outcomes (4)
Reaction time
Reaction time will be assessed using the Light Trainer system. The response time to visual stimuli will be recorded in milliseconds.
Measured: Baseline
Shoulder proprioception
Shoulder joint position sense will be assessed using the joint repositioning test. Absolute error will be recorded in degrees.
Measured: Baseline
Test-retest reliability
Test-retest reliability of the visual-laser feedback map tests will be evaluated using the Intraclass Correlation Coefficient (ICC).
Measured: Baseline and 7-day follow-up
Measurement error
Measurement error will be calculated using the Standard Error of Measurement (SEM) and Minimal Detectable Change (MDC).
Measured: Baseline and 7-day follow-up
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 May 2026
- Study start15 Apr 2026
- Primary completion28 Apr 2026
- Study completion15 Jul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (6)Papers the sponsor has linked to this study.
- Other trials for Motoric Cognitive Risk SyndromeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 35 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Balikesir University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ebru Tekin, Balikesir University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07572942
- Sponsor's protocol ID
- 2026/47
- Status last verified
- May 2026
- First submitted
- 1 May 2026
- Last updated
- 7 May 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Pinzón-Ríos, I. D., & Moreno-Collazos, J. E. (2020). Neural aging, brain plasticity and exercise: Advances from a physiotherapy perspective. Archivos de Medicina (Manizales), 20(1), 188-202.
Koo TK, Li MY. A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research. J Chiropr Med. 2016 Jun;15(2):155-63. doi: 10.1016/j.jcm.2016.02.012. Epub 2016 Mar 31.
PubMed 27330520Shadmehr R, Krakauer JW. A computational neuroanatomy for motor control. Exp Brain Res. 2008 Mar;185(3):359-81. doi: 10.1007/s00221-008-1280-5. Epub 2008 Feb 5.
PubMed 18251019Moinuddin A, Goel A, Sethi Y. The Role of Augmented Feedback on Motor Learning: A Systematic Review. Cureus. 2021 Nov 18;13(11):e19695. doi: 10.7759/cureus.19695. eCollection 2021 Nov.
PubMed 34976475Clark DJ. Automaticity of walking: functional significance, mechanisms, measurement and rehabilitation strategies. Front Hum Neurosci. 2015 May 5;9:246. doi: 10.3389/fnhum.2015.00246. eCollection 2015.
PubMed 25999838Seidler RD, Bernard JA, Burutolu TB, Fling BW, Gordon MT, Gwin JT, Kwak Y, Lipps DB. Motor control and aging: links to age-related brain structural, functional, and biochemical effects. Neurosci Biobehav Rev. 2010 Apr;34(5):721-33. doi: 10.1016/j.neubiorev.2009.10.005. Epub 2009 Oct 20.
PubMed 19850077
Study at a glance
From the registry record, last updated by the sponsor on 7 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Validity and Reliability of Neuroscience-Based Visual Laser Feedback Map Tests in Individuals With Motoric Cognitive Risk Syndrome
- ClinicalTrials.gov ID
- NCT07572942
- Acronym / sponsor ID
- 2026/47
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 35 participants (estimated)
- Lead sponsor
- Balikesir UniversityUniversity, hospital or other
- Study start
- 15 Apr 2026 (actual)
- Primary completion
- 28 Apr 2026 (actual)
- Study completion
- 15 Jul 2026 (estimated)
- First posted
- 7 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate the validity and reliability of neuroscience-based visual laser feedback map tests in individuals with Motoric Cognitive Risk Syndrome (MCRS). The developed assessment protocol integrates visuospatial processing, reaction time, and upper extremity motor control within a single task. Construct validity will be examined through correlations with reaction time and proprioception measurements, and test-retest reliability will be assessed to determine measurement consistency.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Motoric Cognitive Risk Syndrome Group | – | –Community-dwelling older adults aged 65 years and above diagnosed with Motoric Cognitive Risk Syndrome (MCRS) will be included. Participants will undergo neuroscience-based visual-laser feedback map tests along with reaction time and proprioception assessments under standardized conditions. No therapeutic intervention will be applied. |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
- Study population
- Community-dwelling older adults aged 65 years and above diagnosed with Motoric Cognitive Risk Syndrome will be recruited from the Tazelenme University Coordination Unit in Balıkesir, Turkey. The study population represents individuals at risk of cognitive decline but without diagnosed dementia, enabling the evaluation of early-stage cognitive-motor interaction.
Key inclusion criteria (1 listed)
- Aged ≥65 years Diagnosis of Motoric Cognitive Risk Syndrome (subjective cognitive complaint + slow gait) Living independently in the community Able to understand and perform test procedures
Key exclusion criteria (1 listed)
- Diagnosed dementia Severe psychiatric disorders Advanced visual impairments (e.g., macular degeneration, severe cataract) Neurological disorders affecting motor control Severe tremor or ataxia interfering with task performance
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Visual-laser feedback map test performance
Time frame: Baseline
Performance parameters including completion time (seconds), reaction time (milliseconds), movement accuracy, and total performance score obtained from the figure-of-eight tracing and directional target tracking tasks.
4 secondary outcomes
Reaction time
Time frame: Baseline
Shoulder proprioception
Time frame: Baseline
Test-retest reliability
Time frame: Baseline and 7-day follow-up
Measurement error
Time frame: Baseline and 7-day follow-up
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 May 2026.
- BackgroundPinzón-Ríos, I. D., & Moreno-Collazos, J. E. (2020). Neural aging, brain plasticity and exercise: Advances from a physiotherapy perspective. Archivos de Medicina (Manizales), 20(1), 188-202.
- Background: PubMed 27330520Koo TK, Li MY. A Guideline of Selecting and Reporting Intraclass Correlation Coefficients for Reliability Research. J Chiropr Med. 2016 Jun;15(2):155-63. doi: 10.1016/j.jcm.2016.02.012. Epub 2016 Mar 31.
- Background: PubMed 18251019Shadmehr R, Krakauer JW. A computational neuroanatomy for motor control. Exp Brain Res. 2008 Mar;185(3):359-81. doi: 10.1007/s00221-008-1280-5. Epub 2008 Feb 5.
- Background: PubMed 34976475Moinuddin A, Goel A, Sethi Y. The Role of Augmented Feedback on Motor Learning: A Systematic Review. Cureus. 2021 Nov 18;13(11):e19695. doi: 10.7759/cureus.19695. eCollection 2021 Nov.
- Background: PubMed 25999838Clark DJ. Automaticity of walking: functional significance, mechanisms, measurement and rehabilitation strategies. Front Hum Neurosci. 2015 May 5;9:246. doi: 10.3389/fnhum.2015.00246. eCollection 2015.
- Background: PubMed 19850077Seidler RD, Bernard JA, Burutolu TB, Fling BW, Gordon MT, Gwin JT, Kwak Y, Lipps DB. Motor control and aging: links to age-related brain structural, functional, and biochemical effects. Neurosci Biobehav Rev. 2010 Apr;34(5):721-33. doi: 10.1016/j.neubiorev.2009.10.005. Epub 2009 Oct 20.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Motoric Cognitive Risk Syndrome and Cognitive-Motor Interaction, run by Balikesir University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 7 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ebru Tekin, Lecturer (+90 266 614 69 11, ebrutekin123@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Visual-laser feedback map test performance (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07572942, which also lists 6 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 May 2026.