Clinical trials: Motoric Cognitive Risk Syndrome
Motoric Cognitive Risk Syndrome, Elderly (People Aged 65 or More)
Effect of Exergaming Program Versus Neuromuscular Exercise in Elderly People With Motor Cognitive Risk Syndrome
The primary aim of our study is to compare the effects of neuromuscular exercise training versus structured exergaming program on locomotor and cognitive functions in elderly individuals with Motor Cognitive Risk (MCR), which…
- Conditions
- Motoric Cognitive Risk Syndrome, Elderly (People Aged 65 or More), Geriatric Patient, Exergaming
- Trial name
- NCT07045259
- Testing
- The Neuromuscular Exercise Training program, Exergaming Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University - Cerrahpasa
Cognitive Impairment, Motoric Cognitive Risk Syndrome
Pre-FRONTal Brain STability, Key for Action Against Disability in AGing
Cognitive and mobility impairments are critical contributors to dementia and disability in older adults, and can be caused by neurodegenerative and neurovascular changes at the pre-frontal (PF) brain areas.
- Trial name
- FRONT STAGE (NCT04115215)
- Testing
- Physical exercise (PE), Transcranial current stimulation (tCS), Control
- Where
- 5 sites in Spain
- Volunteers
- 93 people
- Sponsor
- Parc Sanitari Pere Virgili
Motoric Cognitive Risk Syndrome, Cognitive-Motor Interaction
Laser-Based Map Tests in Motoric Cognitive Risk Syndrome
This study aims to evaluate the validity and reliability of neuroscience-based visual laser feedback map tests in individuals with Motoric Cognitive Risk Syndrome (MCRS).
- Conditions
- Motoric Cognitive Risk Syndrome, Cognitive-Motor Interaction, Sensorimotor Performance
- Trial name
- NCT07572942
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Balikesir University
Motoric Cognitive Risk Syndrome
Home Transcranial Direct-Current Stimulation for Motoric Cognitive Risk Syndrome
1. To examine the effect of a two-week tDCS intervention of 3 months of continued tDCS intervention versus 3 months of receiving a placebo treatment (dummy).
- Trial name
- HometDCS (NCT06581458)
- Testing
- tDCS
- Volunteers
- 64 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Depressive Disorder, Treatment-Resistant
Accelerated Bilateral Sequential Theta Burst Stimulation in Older Adults With Treatment-resistant Depression
The CogniTReaD study is a pilot clinical trial that will compare the effects of active accelerated bilateral sequential theta burst stimulation (absTBS) and sham or inactive treatment.
- Trial name
- CogniTReaD (NCT06323486)
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- Ontario Shores Centre for Mental Health Sciences
Cognitive-prefrailty, Prefrailty
The Cognitive-Prefrail Syndrome and Its Association With Adverse Health Outcomes
Lay Summary Older adults who are prefrail (an intermediate, potentially reversible stage between robustness and frailty) with early symptoms of cognitive impairment are a segment of the population that have hitherto remained…
- Conditions
- Cognitive-prefrailty, Prefrailty, Motoric Cognitive Risk Syndrome
- Trial name
- NCT04240028
- Testing
- Data Collection
- Where
- Canada
- Volunteers
- 1,741 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Motoric Cognitive Risk Syndrome
Motor-Cognitive Training for Motoric Cognitive Risk Syndrome
The goal of this clinical trial is to investigate if combined motor-cognitive training can improve motor and cognitive symptoms in older adults with motoric cognitive risk syndrome.
- Trial name
- VRTT for MCR (NCT07223905)
- Testing
- Virtual Reality Treadmill Training, Treadmill Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Kansas Medical Center
Frailty, Motoric Cognitive Risk Syndrome
Cognitive Prefrail and Frailty, and Motoric Cognitive Risk Syndrome: Prevalence and Association With Incident Adverse Health Events
We defined a new and early condition in the spectrum of cognitive frailty: the "cognitive-prefrailty" which is a combination of prefrailty stage and subjective cognitive impairment (SCI).
- Conditions
- Frailty, Motoric Cognitive Risk Syndrome, Cognitive-prefrailty
- Trial name
- NCT04275817
- Testing
- Data collection
- Where
- Canada
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Physical Activities, Motoric Cognitive Risk Syndrome
Effect of Episodic Future Thinking on Promoting Physical Activity Among Older Adults With Motoric Cognitive Risk Syndrome: A Randomized Controlled Trial
Motor Cognitive Risk (MCR), a pre-dementia state characterized by the coexistence of subjective cognitive decline (SCD) and slow gait speed, has a high prevalence among community-dwelling older adults in China and is associated…
- Trial name
- NCT07554027
- Testing
- Episodic Future Thinking, Brochure-Based Health Education
- Where
- China
- Volunteers
- 166 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Depression, Geriatrics
Motoric Cognitive Risk and Depression
The overall objective of the proposal is to examine the association between depression and the newly reported "motoric cognitive risk" (MCR) syndrome, which is a pre-dementia syndrome combining subjective cognitive complaint…
- Conditions
- Depression, Geriatrics, Neurocognitive Disorders
- Trial name
- NCT03679221
- Testing
- Data collection
- Where
- Canada
- Volunteers
- 30,000 people
- Sponsor
- Jewish General Hospital
Motoric Cognitive Risk Syndrome
Personalized Exercise Treatments for Older Veterans With Motoric Cognitive Risk Syndrome
This study will begin to evaluate personalized preventative dementia treatments for Veterans at risk for developing dementia. The investigators will target Veterans with Motoric Cognitive Risk syndrome (MCR), which is…
- Trial name
- NCT06451874
- Testing
- Functional Power Training (FPT), Music-Based Digital Therapy (MBDT), FPT + MBDT
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- VA Office of Research and Development
Cognition Disorders, Aged
Moderate-Intensity Aerobic Calisthenics for Rural Elderly With Motoric Cognitive Risk Syndrome
The aging of China's rural population is severe, with both the prevalence and mortality rates of dementia higher in rural areas than in urban areas.
- Trial name
- NCT07658469
- Testing
- moderate-intensity aerobic exercise, Routine Care
- Where
- China
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Fujian Provincial Hospital
Cognition Disorders in Old Age, Dementia
The "Motoric Cognitive Risk" Syndrome in the Quebec Population
The overall objective of the proposal is to examine the epidemiology of the newly reported "motoric cognitive risk" (MCR) syndrome, which is a pre-dementia syndrome combining subjective cognitive complaint (i.e.; memory…
- Trial name
- NCT03633253
- Testing
- Summarize of participants' characteristics using means and standard deviations or frequencies and percentages
- Where
- Canada
- Volunteers
- 1,741 people, healthy volunteers welcome
- Sponsor
- Jewish General Hospital
Motoric Cognitive Risk Syndrome, Gait
Figure-of-8 Walk Test in Individuals With Motoric Cognitive Risk Syndrome
This observational study aims to investigate the validity and reliability of the Figure-of-8 Walk Test (8FWT) in individuals with Motoric Cognitive Risk Syndrome (MCRS).
- Conditions
- Motoric Cognitive Risk Syndrome, Gait, Balance
- Trial name
- 8FWT-MCR (NCT07586553)
- Testing
- Assessment Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Balikesir University
Disability Physical, Disabilities Mental
Combined Motor and Cognitive Training for Older Adults With Motoric Cognitive Risk Syndrome (CMC-training)
To investigate the effects of a combined motor-cognitive intervention on the improvement of motor as well as cognitive function in community residents.
- Conditions
- Disability Physical, Disabilities Mental, Age Problem
- Trial name
- NCT06542601
- Testing
- Motor cognitive intervention
- Where
- China
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Motoric Cognitive Risk Syndrome, Aging Disorder
MCR Syndrome in Quebec : Results From NuAge Study
The overall objective of the proposal is to examine the epidemiology of the newly reported "motoric cognitive risk" (MCR) syndrome, which is a pre-dementia syndrome combining subjective cognitive complaint (i.e.; memory…
- Trial name
- NCT05046275
- Testing
- Data analysis
- Where
- Canada
- Volunteers
- 1,741 people
- Sponsor
- Centre integre universitaire de sante et de services sociaux du Centre-Sud-de-l'Île-de-Montréal
Motoric Cognitive Risk Syndrome, Dual-Task Performance
Dual-Task Effects on Gait and Balance in MCRS
This study aims to investigate the effects of cognitive load on gait and balance performance in individuals with Motoric Cognitive Risk Syndrome (MCRS).
- Conditions
- Motoric Cognitive Risk Syndrome, Dual-Task Performance, Gait, Balance
- Trial name
- NCT07572968
- Testing
- Assessment Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Balikesir University
Cognition Disorders in Old Age, Cardiovascular Diseases
The "Motoric Cognitive Risk" Syndrome in the Canadian Population
Cognition and locomotion are two human abilities controlled by the brain. Their decline is highly prevalent with aging, and is greater than the simple sum of their respective prevalence, suggesting a complex age-related interplay…
- Conditions
- Cognition Disorders in Old Age, Cardiovascular Diseases, Dementia
- Trial name
- MCR-CardioV (NCT03679026)
- Testing
- Summarize of participants' characteristics using means and standard deviations or frequencies and percentages
- Where
- Canada
- Volunteers
- 1,461 people
- Sponsor
- Jewish General Hospital
Alzheimer Disease and Related Dementias, Cognition
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function…
- Conditions
- Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
- Trial name
- TDCS4MCR (NCT06821568)
- Testing
- Personalized Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States, Israel
- Volunteers
- 128 people
- Sponsor
- Hebrew SeniorLife
Motoric Cognitive Risk Syndrome, Mild Cognitive Impairment
Ginkgo Leaf Extract and Armillariella Mellea Powder Oral Solution for the Treatment of Motoric Cognitive Risk Syndrome
This is a multi-centre, randomised, double blind, placebo controlled study on participants with Motoric Cognitive Risk Syndrome to evaluate the efficacy and safety of Ginkgo Leaf Extract and Armillariella Mellea Powder Oral…
- Conditions
- Motoric Cognitive Risk Syndrome, Mild Cognitive Impairment, Aging, Locomotive Syndrome
- Trial name
- NCT04492241
- Testing
- Ginkgo Leaf Extract and Armillariella Mellea Powder Oral Solution, Simulation of Ginkgo Leaf Extract and Armillariella Mellea Powder Oral Solution
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Beijing Tiantan Hospital