Motoric Cognitive Risk SyndromeNCT07572968
Dual-Task Effects on Gait and Balance in MCRS
An observational study of Motoric Cognitive Risk Syndrome and Dual-Task Performance, run by Balikesir University at 1 site in Turkey (Türkiye).
Trial summary
This study aims to investigate the effects of cognitive load on gait and balance performance in individuals with Motoric Cognitive Risk Syndrome (MCRS). Participants will perform Timed Up and Go (TUG) and tandem walking tests under single-task and dual-task conditions. Read more about this study
- Who is it for?
- Ages 65 years and older
- Conditions the study is for
- Motoric Cognitive Risk Syndrome, Dual-Task Performance, Gait
- What is being tested?
- Assessment Protocol
- How many people
- 35 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 15 Apr 2026to 15 Jul 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- No healthy volunteers
- Older adult
Study population: Community-dwelling older adults aged 65 years and above diagnosed with Motoric Cognitive Risk Syndrome in Balıkesir, Turkey.
Who may be able to join
- Age ≥ 65 years Subjective cognitive complaints Slow gait speed No dementia diagnosis
Who cannot join
- Severe visual/hearing impairment Neurological diseases (stroke, Parkinson) Acute orthopedic conditions affecting walking
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Balikesir University
Balıkesir, Bigadiç
Ebru Tekin, Lecturer, +90 266 614 69 11, ebrutekin123@gmail.com
About this study
Official title: Effects of Cognitive Load on Gait and Balance Performance in Individuals With Motoric Cognitive Risk Syndrome: A Dual-Task Analysis
This study aims to investigate the effects of cognitive load on gait and balance performance in individuals with Motoric Cognitive Risk Syndrome (MCRS). Participants will perform Timed Up and Go (TUG) and tandem walking tests under single-task and dual-task conditions. The study evaluates cognitive-motor interference and dual-task cost to better understand early markers of cognitive decline and fall risk.
- Conditions
- Motoric Cognitive Risk Syndrome, Dual-Task Performance, Gait, Balance
- Being tested
- Assessment Protocol
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Assessment ProtocolOther
Participants will undergo standardized Timed Up and Go (TUG) and tandem walking assessments under single-task and dual-task conditions. Cognitive dual-task conditions will include serial subtraction while performing the motor task. No therapeutic intervention, exercise training, or treatment will be applied.
| Study group | Role | What they receive |
|---|---|---|
| Motoric Cognitive Risk Syndrome Group | Community-dwelling older adults aged 65 years and above diagnosed with Motoric Cognitive Risk Syndrome will be included. Participants will perform Timed Up and Go (TUG) and tandem walking tests under single-task and dual-task conditions. No intervention will be applied. Receives: Other: Assessment Protocol |
What is being measured
The primary outcome is the main question the study is designed to answer.
Timed Up and Go (TUG) performance
Functional mobility will be assessed using the Timed Up and Go (TUG) test. Participants will stand up from a standard chair (approximately 46 cm), walk 3 meters, turn around a marker, return, and sit down. Performance time will be recorded in seconds under three conditions:
single-task (baseline), physical dual-task (carrying a cup of water), and cognitive dual-task (serial subtraction task).
Measured: Baseline (single session assessment)
Secondary outcomes (4)
Tandem walking test performance
Static and dynamic balance will be assessed using tandem walking. Participants will walk in a heel-to-toe position under two conditions:
single-task, cognitive dual-task (serial subtraction). Performance time will be recorded in seconds.
Measured: Baseline
Dual-task cost (%)
Dual-task cost will be calculated to quantify the decline in performance under dual-task conditions compared to single-task performance. It will be expressed as a percentage using standard formulas for both TUG and tandem tests.
Measured: Baseline
Gait speed
Walking speed will be derived from the TUG test and expressed in meters per second (m/s) under single and dual-task conditions.
Measured: Baseline
Cognitive-motor interference
Performance deterioration during dual-task conditions will be evaluated to assess cognitive-motor interference effects in individuals with Motoric Cognitive Risk Syndrome.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 May 2026
- Study start15 Apr 2026
- Primary completion28 Apr 2026
- Study completion15 Jul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for Motoric Cognitive Risk SyndromeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 35 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Balikesir University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ebru Tekin, Balikesir University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07572968
- Sponsor's protocol ID
- 2026/49
- Status last verified
- May 2026
- First submitted
- 1 May 2026
- Last updated
- 7 May 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Sekhon, H., Allali, G., & Beauchet, O. (2022). Dual-task cost of gait in Motoric Cognitive Risk Syndrome: A cross-sectional study. Frontiers in Aging Neuroscience, 14, 843575.
Montero-Odasso, M., Almeida, Q. J., Burhan, A. M., Camicioli, R., Doyon, J., Fraser, S., et al. (2020). Gait and cognition: The dual-task approach as a window into the aging brain. The Journals of Gerontology Series A, 75(11), 2157-2165.
Beauchet, O., Sekhon, H., Launay, C. P., Chabot, J., & Allali, G. (2022). Gait variability and Motoric Cognitive Risk Syndrome: A systematic review. Frontiers in Aging Neuroscience, 14, 856004.
Beauchet, O., Allali, G., Sekhon, H., Verghese, J., Guilain, S., Steinmetz, J. P., & Launay, C. P. (2021). Motoric Cognitive Risk Syndrome and incident dementia: Results from a comparative meta-analysis. Journal of the American Medical Directors Association, 22(8), 1642-1649.
Allali, G., Aybek, S., Launay, C. P., Adam, S., Azizy, M., & Beauchet, O. (2023). Cognitive-gait interference in pre-dementia syndromes: A systematic review. Journal of Alzheimer's Disease, 92(1), 15-28.
Study at a glance
From the registry record, last updated by the sponsor on 7 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Cognitive Load on Gait and Balance Performance in Individuals With Motoric Cognitive Risk Syndrome: A Dual-Task Analysis
- ClinicalTrials.gov ID
- NCT07572968
- Acronym / sponsor ID
- 2026/49
- Conditions
- Motoric Cognitive Risk Syndrome, Dual-Task Performance, Gait, Balance
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 35 participants (estimated)
- Lead sponsor
- Balikesir UniversityUniversity, hospital or other
- Study start
- 15 Apr 2026 (actual)
- Primary completion
- 28 Apr 2026 (actual)
- Study completion
- 15 Jul 2026 (estimated)
- First posted
- 7 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to investigate the effects of cognitive load on gait and balance performance in individuals with Motoric Cognitive Risk Syndrome (MCRS). Participants will perform Timed Up and Go (TUG) and tandem walking tests under single-task and dual-task conditions. The study evaluates cognitive-motor interference and dual-task cost to better understand early markers of cognitive decline and fall risk.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Motoric Cognitive Risk Syndrome Group | – | Other: Assessment ProtocolCommunity-dwelling older adults aged 65 years and above diagnosed with Motoric Cognitive Risk Syndrome will be included. Participants will perform Timed Up and Go (TUG) and tandem walking tests under single-task and dual-task conditions. No intervention will be applied. |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
- Study population
- Community-dwelling older adults aged 65 years and above diagnosed with Motoric Cognitive Risk Syndrome in Balıkesir, Turkey.
Key inclusion criteria (1 listed)
- Age ≥ 65 years Subjective cognitive complaints Slow gait speed No dementia diagnosis
Key exclusion criteria (1 listed)
- Severe visual/hearing impairment Neurological diseases (stroke, Parkinson) Acute orthopedic conditions affecting walking
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Assessment ProtocolParticipants will undergo standardized Timed Up and Go (TUG) and tandem walking assessments under single-task and dual-task conditions. Cognitive dual-task conditions will include serial subtraction while performing the motor task. No therapeutic intervention, exercise training, or treatment will be applied. | Other | Motoric Cognitive Risk Syndrome Group |
Primary outcome
Timed Up and Go (TUG) performance
Time frame: Baseline (single session assessment)
Functional mobility will be assessed using the Timed Up and Go (TUG) test. Participants will stand up from a standard chair (approximately 46 cm), walk 3 meters, turn around a marker, return, and sit down. Performance time will be recorded in seconds under three conditions: single-task (baseline), physical dual-task (carrying a cup of water), and cognitive dual-task (serial subtraction task).
4 secondary outcomes
Tandem walking test performance
Time frame: Baseline
Dual-task cost (%)
Time frame: Baseline
Gait speed
Time frame: Baseline
Cognitive-motor interference
Time frame: Baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 May 2026.
- BackgroundSekhon, H., Allali, G., & Beauchet, O. (2022). Dual-task cost of gait in Motoric Cognitive Risk Syndrome: A cross-sectional study. Frontiers in Aging Neuroscience, 14, 843575.
- BackgroundMontero-Odasso, M., Almeida, Q. J., Burhan, A. M., Camicioli, R., Doyon, J., Fraser, S., et al. (2020). Gait and cognition: The dual-task approach as a window into the aging brain. The Journals of Gerontology Series A, 75(11), 2157-2165.
- BackgroundBeauchet, O., Sekhon, H., Launay, C. P., Chabot, J., & Allali, G. (2022). Gait variability and Motoric Cognitive Risk Syndrome: A systematic review. Frontiers in Aging Neuroscience, 14, 856004.
- BackgroundBeauchet, O., Allali, G., Sekhon, H., Verghese, J., Guilain, S., Steinmetz, J. P., & Launay, C. P. (2021). Motoric Cognitive Risk Syndrome and incident dementia: Results from a comparative meta-analysis. Journal of the American Medical Directors Association, 22(8), 1642-1649.
- BackgroundAllali, G., Aybek, S., Launay, C. P., Adam, S., Azizy, M., & Beauchet, O. (2023). Cognitive-gait interference in pre-dementia syndromes: A systematic review. Journal of Alzheimer's Disease, 92(1), 15-28.
- Individual participant dataSharing planned: No
Related trials for Motoric Cognitive Risk Syndrome
Recruiting
Motor-Cognitive Training for Motoric Cognitive Risk Syndrome
Motoric Cognitive Risk Syndrome
Recruiting
Effect of Exergaming Program Versus Neuromuscular Exercise in Elderly People With Motor Cognitive Risk Syndrome
Motoric Cognitive Risk Syndrome, Elderly (People Aged 65 or More)
Recruiting
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
Alzheimer Disease and Related Dementias, Cognition
Recruiting
Personalized Exercise Treatments for Older Veterans With Motoric Cognitive Risk Syndrome
Motoric Cognitive Risk Syndrome
Not yet recruiting
Moderate-Intensity Aerobic Calisthenics for Rural Elderly With Motoric Cognitive Risk Syndrome
Cognition Disorders, Aged
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Motoric Cognitive Risk Syndrome and Dual-Task Performance, run by Balikesir University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 7 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ebru Tekin, Lecturer (+90 266 614 69 11, ebrutekin123@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Timed Up and Go (TUG) performance (time frame: Baseline (single session assessment)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07572968, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 May 2026.