Benign Paroxysmal Positional VertigoNCT07576088
Multimodal Physiotherapy for Balance and Vertigo in BPPV Patients
A study testing Multimodal Physiotherapy and Epley Maneuver in people with Benign Paroxysmal Positional Vertigo and Vertigo, run by Riphah International University at 1 site in Pakistan.
Trial summary
This study aims to evaluate the effects of a multimodal physiotherapy approach on balance, vertigo, fear of falling, and quality of life in patients with benign paroxysmal positional vertigo (BPPV). Read more about this study
- Who is it for?
- Ages 22 to 79 years
- Conditions the study is for
- Benign Paroxysmal Positional Vertigo, Vertigo, Balance Disorder
- What is being tested?
- Multimodal Physiotherapy and Epley Maneuver
- Type of treatment
- Surgery or procedure, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 46 participants
- Where
- 1 sitePakistan
- Study dates
- 5 Jun 2025to 6 Aug 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 22 to 79 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age group between (22-79). Both the genders Male and Female were included. Diagnosed with posterior canal benign paroxysmal positional vertigo (PC-BPPV) confirmed by a positive Dix-Hall pike maneuver.
- Onset of symptoms within the past 3 months. Dynamic Balance impairment by DGI > 21. All patients had history of at least two or more attacks of BPPV over 6 months.
Who cannot join
- Patients with a history of cervical spine injuries. Patients taking anti-vertigo medication. Patients with a previous diagnosis of Meniere's disease, migraine, or vestibular neuritis Patients with a previous history of neurological diseases. Cases with bilateral involvement. Absence of systemic diseases without medical control and absence of functional limitations that impede independent walking.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effects of Multimodal Physiotherapy Approach on Balance, Vertigo, Fear of Fall, and Quality of Life in Patients With Benign Paroxysmal Positional Vertigo
This study aims to evaluate the effects of a multimodal physiotherapy approach on balance, vertigo, fear of falling, and quality of life in patients with benign paroxysmal positional vertigo (BPPV). BPPV is a common vestibular disorder that causes dizziness and balance problems, leading to an increased risk of falls and reduced quality of life. In this randomized controlled trial, participants will be assigned to two groups: one receiving a multimodal physiotherapy program including patient education, Epley maneuver, and balance training, and the other receiving standard Epley maneuver treatment. The intervention will be conducted over four weeks. Outcomes will be assessed using standardized tools for balance, vertigo, fear of falling, and quality of life. The study aims to determine whether a combined physiotherapy approach provides better outcomes than standard treatment alone.
Read the detailed description
Benign paroxysmal positional vertigo (BPPV) is one of the most common vestibular disorders, characterized by brief episodes of vertigo triggered by changes in head position. It significantly affects balance, mobility, and quality of life, and increases the risk of falls, especially in older adults. Although repositioning maneuvers such as the Epley maneuver are considered the standard treatment, many patients continue to experience residual dizziness, imbalance, and fear of falling.
A multimodal physiotherapy approach that combines patient education, vestibular rehabilitation, and balance training may provide a more comprehensive strategy to address these residual impairments. This approach targets both the vestibular and functional components of recovery, potentially improving overall patient outcomes.
This study is a single-blinded randomized controlled trial designed to evaluate the effects of a multimodal physiotherapy approach compared to standard treatment in patients with BPPV. Participants aged 22 to 79 years diagnosed with BPPV will be recruited using a non-probability convenience sampling technique. Participants will be randomly allocated into two groups: the intervention group receiving patient education, Epley maneuver, and balance training, and the control group receiving only the Epley maneuver. The intervention will be administered three times per week for four weeks.
Outcome measures will include the Dynamic Gait Index for balance, Dizziness Handicap Inventory for vertigo, Falls Efficacy Scale-International for fear of falling, and SF-36 for quality of life. Assessments will be conducted at baseline and after completion of the intervention.
The results of this study will provide evidence on whether a multimodal physiotherapy approach is more effective than standard treatment in improving balance, reducing vertigo symptoms, decreasing fear of falling, and enhancing quality of life in patients with BPPV.
- Being tested
- Multimodal Physiotherapy, Epley Maneuver
- Keywords
- Benign Paroxysmal Positional Vertigo, Balance, Fear of fall, Multimodal Physiotherapy Approach, Quality of Life, Vertigo
- Medical subject headings
- Benign Paroxysmal Positional Vertigo, Vertigo
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Multimodal PhysiotherapyBehavioural
Also called Multimodal Physiotherapy Approach (MPA)
A combined rehabilitation approach including vestibular rehabilitation, patient education, and balance training aimed at improving balance, reducing vertigo, decreasing fear of falling, and enhancing quality of life.
Epley ManeuverProcedure or surgery
A repositioning technique involving sequential head and body movements to relocate displaced otoconia within the semicircular canals to relieve symptoms of benign paroxysmal positional vertigo.
| Study group | Role | What they receive |
|---|---|---|
| Multimodal Physiotherapy | Experimental | participants will receive a multimodal physiotherapy program including patient education, Epley maneuver, and balance training, administered three times per week for four weeks. Receives: Behavioral: Multimodal Physiotherapy; Procedure: Epley Maneuver |
| epley Maneuver | Active comparator | Participants will receive standard treatment using the Epley maneuver, administered three times per week for four weeks. Receives: Procedure: Epley Maneuver |
What is being measured
The primary outcome is the main question the study is designed to answer.
Balance
Balance will be assessed using the Dynamic Gait Index (DGI), a validated tool that evaluates gait, stability, and functional mobility in individuals with balance disorders.
Measured: Baseline and Week 4
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 May 2026
- Study start5 Jun 2025
- Primary completion6 Jul 2026 (estimated)
- Study completion6 Aug 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Benign Paroxysmal Positional VertigoStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Participants will be randomly assigned to two parallel groups: one receiving multimodal physiotherapy (patient education, Epley maneuver, and balance training) and the other receiving standard Epley maneuver treatment.
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 46 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- wajeeha zia, PhD, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07576088
- Sponsor's protocol ID
- M.Usama Latif
- Status last verified
- May 2026
- First submitted
- 4 May 2026
- Last updated
- 8 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: There is no plan to share individual participant data. All data will be kept confidential and used solely for academic and research purposes.
Study at a glance
From the registry record, last updated by the sponsor on 8 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of Multimodal Physiotherapy Approach on Balance, Vertigo, Fear of Fall, and Quality of Life in Patients With Benign Paroxysmal Positional Vertigo
- ClinicalTrials.gov ID
- NCT07576088
- Acronym / sponsor ID
- M.Usama Latif
- Keywords
- Benign Paroxysmal Positional Vertigo, Balance, Fear of fall, Multimodal Physiotherapy Approach, Quality of Life, Vertigo
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 46 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 5 Jun 2025 (actual)
- Primary completion
- 6 Jul 2026 (estimated)
- Study completion
- 6 Aug 2026 (estimated)
- First posted
- 8 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to evaluate the effects of a multimodal physiotherapy approach on balance, vertigo, fear of falling, and quality of life in patients with benign paroxysmal positional vertigo (BPPV). BPPV is a common vestibular disorder that causes dizziness and balance problems, leading to an increased risk of falls and reduced quality of life. In this randomized controlled trial, participants will be assigned to two groups: one receiving a multimodal physiotherapy program including patient education, Epley maneuver, and balance training, and the other receiving standard Epley maneuver treatment. The intervention will be conducted over four weeks. Outcomes will be assessed using standardized tools for balance, vertigo, fear of falling, and quality of life. The study aims to determine whether a combined physiotherapy approach provides better outcomes than standard treatment alone.
Detailed description
Benign paroxysmal positional vertigo (BPPV) is one of the most common vestibular disorders, characterized by brief episodes of vertigo triggered by changes in head position. It significantly affects balance, mobility, and quality of life, and increases the risk of falls, especially in older adults. Although repositioning maneuvers such as the Epley maneuver are considered the standard treatment, many patients continue to experience residual dizziness, imbalance, and fear of falling.
A multimodal physiotherapy approach that combines patient education, vestibular rehabilitation, and balance training may provide a more comprehensive strategy to address these residual impairments. This approach targets both the vestibular and functional components of recovery, potentially improving overall patient outcomes.
This study is a single-blinded randomized controlled trial designed to evaluate the effects of a multimodal physiotherapy approach compared to standard treatment in patients with BPPV. Participants aged 22 to 79 years diagnosed with BPPV will be recruited using a non-probability convenience sampling technique. Participants will be randomly allocated into two groups: the intervention group receiving patient education, Epley maneuver, and balance training, and the control group receiving only the Epley maneuver. The intervention will be administered three times per week for four weeks.
Outcome measures will include the Dynamic Gait Index for balance, Dizziness Handicap Inventory for vertigo, Falls Efficacy Scale-International for fear of falling, and SF-36 for quality of life. Assessments will be conducted at baseline and after completion of the intervention.
The results of this study will provide evidence on whether a multimodal physiotherapy approach is more effective than standard treatment in improving balance, reducing vertigo symptoms, decreasing fear of falling, and enhancing quality of life in patients with BPPV.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
- Model description
- Participants will be randomly assigned to two parallel groups: one receiving multimodal physiotherapy (patient education, Epley maneuver, and balance training) and the other receiving standard Epley maneuver treatment.
| Arm | Type | Receives |
|---|---|---|
| Multimodal Physiotherapy | Experimental | Behavioral: Multimodal Physiotherapy, Procedure: Epley Maneuverparticipants will receive a multimodal physiotherapy program including patient education, Epley maneuver, and balance training, administered three times per week for four weeks. |
| epley Maneuver | Active comparator | Procedure: Epley ManeuverParticipants will receive standard treatment using the Epley maneuver, administered three times per week for four weeks. |
Who may qualify
- Ages
- 22 to 79 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Age group between (22-79). Both the genders Male and Female were included. Diagnosed with posterior canal benign paroxysmal positional vertigo (PC-BPPV) confirmed by a positive Dix-Hall pike maneuver.
- Onset of symptoms within the past 3 months. Dynamic Balance impairment by DGI > 21. All patients had history of at least two or more attacks of BPPV over 6 months.
Key exclusion criteria (1 listed)
- Patients with a history of cervical spine injuries. Patients taking anti-vertigo medication. Patients with a previous diagnosis of Meniere's disease, migraine, or vestibular neuritis Patients with a previous history of neurological diseases. Cases with bilateral involvement. Absence of systemic diseases without medical control and absence of functional limitations that impede independent walking.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Multimodal PhysiotherapyAlso: Multimodal Physiotherapy Approach (MPA)A combined rehabilitation approach including vestibular rehabilitation, patient education, and balance training aimed at improving balance, reducing vertigo, decreasing fear of falling, and enhancing quality of life. | Behavioural | Multimodal Physiotherapy |
| Epley ManeuverA repositioning technique involving sequential head and body movements to relocate displaced otoconia within the semicircular canals to relieve symptoms of benign paroxysmal positional vertigo. | Procedure or surgery | Multimodal Physiotherapy, epley Maneuver |
Primary outcome
Balance
Time frame: Baseline and Week 4
Balance will be assessed using the Dynamic Gait Index (DGI), a validated tool that evaluates gait, stability, and functional mobility in individuals with balance disorders.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 May 2026.
- Individual participant dataSharing planned: No. There is no plan to share individual participant data. All data will be kept confidential and used solely for academic and research purposes.
Related trials for Benign Paroxysmal Positional Vertigo
Recruiting
Effectiveness of Epley Maneuver Versus Semont Maneuver on Dizziness and Balance in Stroke Survivors With Posterior Canal BPPV
Stroke
Not yet recruiting
Epley Versus Semont-plus Maneuver for Benign Paroxysmal Positional Vertigo
Benign Paroxysmal Positional Vertigo (BPPV)
Enrolling by invitationObservational study
Comparison of Two Mechanical Rotation Chairs With Diagnostics of Benign Paroxysmal Positional Vertigo.
Benign Paroxysmal Positional Vertigo (BPPV)
Not yet recruiting
The Effect of Chewing Gum on Dizziness in Patients Diagnosed With Posterior Canal Benign Paroxysmal Positional Vertigo in the Emergency Department
Vertigo Benign Positional, Dizziness
Active, not recruiting
Benign Paroxysmal Positional Vertigo With and Without Vestibular Hypofunction: Protocol for an Integrated Home-Based Exercise With Self-Managed Education Programme
Benign Paroxysmal Positional Vertigo (BPPV), Vestibular Hypofunction
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
wajeeha zia, PhD principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Multimodal Physiotherapy and Epley Maneuver in people with Benign Paroxysmal Positional Vertigo and Vertigo, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 8 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Balance (time frame: Baseline and Week 4). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 May 2026.