Weight LossNCT07577765
Testing a Tailored Approach to Long-Term Weight Loss Success
A study testing Adaptive weight regain prevention in people with Weight Loss and Weight Regain, run by University of Utah at 1 site in United States.
Trial summary
The purpose of this study is to develop and test an adaptive, individually tailored intervention to prevent weight regain in people who have intentionally lost weight. The main questions it aims to answer are: Is an adaptive intervention with tailored re-engagement support feasible for individuals following… Read more about this study
- Who is it for?
- Ages 18 to 65 yearsHealthy volunteers can take part
- Conditions the study is for
- Weight Loss, Weight Regain, Obesity & Overweight
- What is being tested?
- Adaptive weight regain prevention
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 siteUnited States
- Study dates
- 7 Jan 2026to 1 Sep 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- BMI of ≥ 27 prior to weight loss
- Lost ≥ 7% of body mass in the past 6 months
- Weight loss was intentional
- No plans for weight loss surgery in the next 6 months
- Access to a smart device that can download applications and receive text messages
- Able to receive clearance for study participation from primary care provider
Who cannot join
- Pregnant or within 12 months postpartum, or planning pregnancy
- Uncontrolled conditions that affect overall health (cardiovascular, metabolic, renal, pulmonary, psychiatric, thyroid, cancers)
- Food insecure
- Bariatric surgery or cancer treatment within the past 5 years
- Active or recent (<12 months) treatment/diagnosis of an eating disorder
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
University of Utah
Salt Lake City, Utah, 84112
Josh Oliver, 971-645-6693, joshua.oliver@hsc.utah.edu
Tanya Halliday, RD, PhD
About this study
Official title: Pilot Testing an Adaptive Intervention for Weight Loss Maintenance
The purpose of this study is to develop and test an adaptive, individually tailored intervention to prevent weight regain in people who have intentionally lost weight. The main questions it aims to answer are:
- Is an adaptive intervention with tailored re-engagement support feasible for individuals following intentional weight loss?
- Does this intervention prevent weight regain after intentional weight loss?
Read more
Participants will:
- Complete a baseline assessment of body measurements
- Complete surveys on dietary intake, mental health, and physical activity
Participants will also engage in a 26-week program, which involves:
- Receive regular educational texts/emails
- Fill out weekly online survey check-ins
- Weigh themselves at least weekly on a scale provided by the study
- Some participants may receive health coaching during portions of the study.
- Assessments will be repeated for all participants at the end of the intervention period.
- Conditions
- Weight Loss, Weight Regain, Obesity & Overweight
- Being tested
- Adaptive weight regain prevention
- Medical subject headings
- Weight Loss, Obesity, Overweight
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Adaptive weight regain preventionBehavioural
Adaptive intervention that will tailor participant re-engagement with professional support (e.g. health coaches) based on behavioral triggers and anthropometric monitoring (diet changes, weight increase, failure to weigh weekly).
| Study group | Role | What they receive |
|---|---|---|
| Adaptive Intervention | Experimental | Not described Receives: Behavioral: Adaptive weight regain prevention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Feasibility - Participant Retention
Number of participants who continue to participate for all 26 weeks of the study and complete all study activities
Measured: From enrollment to the end of the 26-week monitoring period
Feasibility - Participant Adherence
Number of participants who complete all study activities, including weekly weigh-ins, weekly surveys, and pre/post study visits.
Measured: From enrollment to the end of the 26-week monitoring period
Efficacy - Participant Weight
Measured: From enrollment to the end of the 26-week monitoring period
Efficacy - Participant Dietary Intake
Dietary and nutritional data collected via self-report using the ASA24 (Automated Self-Administered 24-Hour Dietary Assessment Tool). This includes calories, protein, fats, and other nutrition information based on participant self-report of meals.
Measured: From enrollment to the end of the 26-week monitoring period
Efficacy - Eating Self-Efficacy in High-Risk Situations
Eating self-efficacy in high-risk situations will be measured pre- \& post-intervention using the Weight Efficacy Lifestyle Questionnaire.
Measured: From enrollment to the end of the 26-week monitoring period
Efficacy - Eating Behavior Patterns
Eating behavior patterns will be measured pre- \& post-intervention using the Three-Factor Eating Questionnaire.
Measured: From enrollment to the end of the 26-week monitoring period
Efficacy - Sleep/Rest Duration
Sleep/rest duration will be measured in hours/day using the activPAL accelerometer, a thigh-worn device that objectively measures posture and movement. Participants will wear the device continuously for 7 consecutive days.
Measured: From enrollment to the end of the 26-week monitoring period
Efficacy - Daily Step Count
Daily step count will be measured using the activPAL accelerometer, a thigh-worn device that objectively measures posture and movement. Participants will wear the device continuously for 7 consecutive days.
Measured: From enrollment to the end of the 26-week monitoring period
Efficacy - Sedentary Behavior (Sitting/Lying Time)
Sedentary behavior will be measured in hours/day using the activPAL accelerometer, a thigh-worn device that objectively measures posture and movement. Participants will wear the device continuously for 7 consecutive days.
Measured: From enrollment to the end of the 26-week monitoring period
Efficacy - Standing Time
Standing time will be measured in hours/day using the activPAL accelerometer, a thigh-worn device that objectively measures posture and movement. Participants will wear the device continuously for 7 consecutive days.
Measured: From enrollment to the end of the 26-week monitoring period
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 May 2026
- Study start7 Jan 2026
- Primary completion1 Sep 2027 (estimated)
- Study completion1 Sep 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Weight LossStudies of the same condition, open and under way.
- More trials run by University of UtahThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Utah
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Tanya Halliday, University of Utah
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07577765
- Sponsor's protocol ID
- IRB_00188310
- Other IDs
- 1K01DK134800-01A1
- Status last verified
- May 2026
- First submitted
- 6 Apr 2026
- Last updated
- 11 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 11 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Pilot Testing an Adaptive Intervention for Weight Loss Maintenance
- ClinicalTrials.gov ID
- NCT07577765
- Acronym / sponsor ID
- IRB_00188310
- Conditions
- Weight Loss, Weight Regain, Obesity & Overweight
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- University of UtahUniversity, hospital or other
- Collaborators
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- Study start
- 7 Jan 2026 (actual)
- Primary completion
- 1 Sep 2027 (estimated)
- Study completion
- 1 Sep 2027 (estimated)
- First posted
- 11 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to develop and test an adaptive, individually tailored intervention to prevent weight regain in people who have intentionally lost weight. The main questions it aims to answer are:
- Is an adaptive intervention with tailored re-engagement support feasible for individuals following intentional weight loss?
- Does this intervention prevent weight regain after intentional weight loss?
Participants will:
- Complete a baseline assessment of body measurements
- Complete surveys on dietary intake, mental health, and physical activity
Participants will also engage in a 26-week program, which involves:
- Receive regular educational texts/emails
- Fill out weekly online survey check-ins
- Weigh themselves at least weekly on a scale provided by the study
- Some participants may receive health coaching during portions of the study.
- Assessments will be repeated for all participants at the end of the intervention period.
Study design
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Adaptive Intervention | Experimental | Behavioral: Adaptive weight regain prevention |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- BMI of ≥ 27 prior to weight loss
- Lost ≥ 7% of body mass in the past 6 months
- Weight loss was intentional
- No plans for weight loss surgery in the next 6 months
- Access to a smart device that can download applications and receive text messages
Key exclusion criteria (5 listed)
- Pregnant or within 12 months postpartum, or planning pregnancy
- Uncontrolled conditions that affect overall health (cardiovascular, metabolic, renal, pulmonary, psychiatric, thyroid, cancers)
- Food insecure
- Bariatric surgery or cancer treatment within the past 5 years
- Active or recent (<12 months) treatment/diagnosis of an eating disorder
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Adaptive weight regain preventionAdaptive intervention that will tailor participant re-engagement with professional support (e.g. health coaches) based on behavioral triggers and anthropometric monitoring (diet changes, weight increase, failure to weigh weekly). | Behavioural | Adaptive Intervention |
Primary outcome
Feasibility - Participant Retention
Time frame: From enrollment to the end of the 26-week monitoring period
Number of participants who continue to participate for all 26 weeks of the study and complete all study activities
Feasibility - Participant Adherence
Time frame: From enrollment to the end of the 26-week monitoring period
Number of participants who complete all study activities, including weekly weigh-ins, weekly surveys, and pre/post study visits.
Efficacy - Participant Weight
Time frame: From enrollment to the end of the 26-week monitoring period
Efficacy - Participant Dietary Intake
Time frame: From enrollment to the end of the 26-week monitoring period
Dietary and nutritional data collected via self-report using the ASA24 (Automated Self-Administered 24-Hour Dietary Assessment Tool). This includes calories, protein, fats, and other nutrition information based on participant self-report of meals.
Efficacy - Eating Self-Efficacy in High-Risk Situations
Time frame: From enrollment to the end of the 26-week monitoring period
Eating self-efficacy in high-risk situations will be measured pre- \& post-intervention using the Weight Efficacy Lifestyle Questionnaire.
Efficacy - Eating Behavior Patterns
Time frame: From enrollment to the end of the 26-week monitoring period
Eating behavior patterns will be measured pre- \& post-intervention using the Three-Factor Eating Questionnaire.
Efficacy - Sleep/Rest Duration
Time frame: From enrollment to the end of the 26-week monitoring period
Sleep/rest duration will be measured in hours/day using the activPAL accelerometer, a thigh-worn device that objectively measures posture and movement. Participants will wear the device continuously for 7 consecutive days.
Efficacy - Daily Step Count
Time frame: From enrollment to the end of the 26-week monitoring period
Daily step count will be measured using the activPAL accelerometer, a thigh-worn device that objectively measures posture and movement. Participants will wear the device continuously for 7 consecutive days.
Efficacy - Sedentary Behavior (Sitting/Lying Time)
Time frame: From enrollment to the end of the 26-week monitoring period
Sedentary behavior will be measured in hours/day using the activPAL accelerometer, a thigh-worn device that objectively measures posture and movement. Participants will wear the device continuously for 7 consecutive days.
Efficacy - Standing Time
Time frame: From enrollment to the end of the 26-week monitoring period
Standing time will be measured in hours/day using the activPAL accelerometer, a thigh-worn device that objectively measures posture and movement. Participants will wear the device continuously for 7 consecutive days.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 May 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Adaptive weight regain prevention in people with Weight Loss and Weight Regain, run by University of Utah at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 11 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Josh Oliver (971-645-6693, joshua.oliver@hsc.utah.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Feasibility - Participant Retention (time frame: From enrollment to the end of the 26-week monitoring period). The study lists 10 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 May 2026.