Burn ScarNCT07578883
Scar Mobilization Improves Scars and Quality of Life in Burned Children.
A study testing Scar tissue mobilization in people with Burn Scar, run by Riphah International University at 1 site in Pakistan.
Trial summary
This quasi-experimental study evaluates the effect of scar tissue mobilization on scar thickness, pliability, and quality of life in children with upper extremity burns. Conducted at Mayo Hospital Lahore, children aged 8-13 will receive treatment for 5 weeks, with outcomes analyzed using SPSS 27. Read more about this study
- Who is it for?
- Ages 8 to 13 years
- Conditions the study is for
- Burn Scar
- What is being tested?
- Scar tissue mobilization
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 15 participants
- Where
- 1 sitePakistan
- Study dates
- 14 Apr 2026to 25 Jul 2026
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 8 to 13 years
- All sexes
- No healthy volunteers
- Child
Who may be able to join
- 8-13 years
- Stable scar and referred for scar management
- Affected upper extremity joints (shoulder, elbow and wrist) with burned injuries
- Partial thickness and full thickness burn.
Who cannot join
- Pre-existing skin condition or allergies
- Neurological disorders affecting motor function
- Fracture with burn in upper limbs
- Patient with only superficial burns
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Institute of Child Health and Children Hospital Lahore
Lahore, Punjab Province, 54000
About this study
Official title: Effects of the Scar Tissue Mobilization on Scar Thickness, Pliability and Quality of Life in Children With Upper Extremity Burns.
This quasi-experimental study evaluates the effect of scar tissue mobilization on scar thickness, pliability, and quality of life in children with upper extremity burns. Conducted at Mayo Hospital Lahore, children aged 8-13 will receive treatment for 5 weeks, with outcomes analyzed using SPSS 27.
Read the detailed description
Burn injuries, especially to the upper extremities, are common in children and can lead to hypertrophic scarring, resulting in pain, stiffness, and reduced range of motion. These complications significantly impact a child's ability to perform daily activities and affect overall quality of life and development. Rehabilitation plays a vital role in recovery, with scar tissue mobilization being a key intervention to improve scar flexibility and function. While commonly used, there is limited evidence on its specific effects in pediatric upper limb burns. This study aims to assess the impact of scar tissue mobilization on scar thickness, pliability and quality of life in children with upper extremity burns.
The study design will be Quasi experimental study. The data will be collected from mayo hospital, Lahore. The study will be completed in 10 months after the approval of synopsis. Children aged 8 to 13 years old will be included in this study and each patient will receive the same intervention. The participants will receive scar tissue mobilization intervention for 15 minutes twice a week for 5 weeks. Participants fulfilling the eligibility criteria will be asked to assign the consent form before entering into the study. The scar thickness and pliability will be measure from the Vancouver Scar Scale (VSS) and quality of life with Brisbane Scar Impact Profile (BBSIP). The synopsis will be presented to Research Ethical Committee of Riphah International University, Lahore for ethical approval to conduct this study. Data will be analyzed through SPSS 27.
- Conditions
- Burn Scar
- Being tested
- Scar tissue mobilization
- Keywords
- Scar tissue mobilization, Quality of life, Scar thickness, Pliability
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Scar tissue mobilizationOther
15-minute massage twice weekly for 5 weeks using baby oil by the same therapist. Included moderate-pressure strokes, finger pressing, circular movements, skin rolling, and finishing gliding strokes.
| Study group | Role | What they receive |
|---|---|---|
| Scar Tissue Mobilization on Scars and Quality of Life in Pediatric Upper Extremity Burns | Experimental | Patients received 15-minute massage sessions twice weekly for 5 weeks by the same therapist. Techniques included moderate-pressure strokes around wounds. Receives: Other: Scar tissue mobilization |
What is being measured
The primary outcome is the main question the study is designed to answer.
vancouver scar scale
The Vancouver Scar Scale (VSS) is a widely used semi-quantitative tool for scar assessment that evaluates four parameters: vascularity, pigmentation, pliability, and height/thickness. It has a total score range of 0-13/14, where 0 indicates normal skin and higher scores represent more severe scarring, including thick scars and contractures.
Measured: Baseline, 5 week
Brisbane burn scar impact profile (BBSIP)
A 40-item scale assessing children's quality of life across domains such as daily activities, hand function, appearance, psychological status, social relationships, and school activities. Items are scored from 0 (not at all) to 4 (a lot), with total scores classified as good (40-80), fair (80-100), and poor (>100). A 58-item burn scar-specific HRQoL self-report tool covering 10 domains including sensory, mobility, daily living, social interaction, appearance, and emotional reactions. Items use dichotomous, 11-point, or 5-point Likert scales; scores are calculated per domain, with lower scores indicating better quality of life.
Measured: Baseline, 5 week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 May 2026
- Study start14 Apr 2026
- Primary completion5 Jul 2026
- Study completion25 Jul 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Burn ScarStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Model description
- Conducted as quasi experimental study, this study will include 15 pediatric burn patients aged 8-13, recruited from mayo hospital and Jinnah hospital Lahore. The participants receiving scar tissue mobilization. In this all patients receiving same intervention. Outcome measures, including scar thickness and pliability (via Vancouver scar scale), and quality of life (via Brisbane scar impact profile BBSIP). Statistical analysis will be performed using SPSS version 27 to determine the intervention effects.
- Masking
- None (open label)
- Enrolment
- 15 participants (actual)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Areej Saher, MS-PT, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07578883
- Sponsor's protocol ID
- REC/RCR&AHS/25/0713
- Status last verified
- Sep 2026
- First submitted
- 5 May 2026
- Last updated
- 30 Sep 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Edger-Lacoursiere Z, Zhu M, Jean S, Marois-Page E, Nedelec B. Evidence Supporting Conservative Scar Management Interventions Following Burn Injury: A Review Article. J Burn Care Res. 2025 Aug 12;46(3):504-514. doi: 10.1093/jbcr/irae204.
PubMed 39548761
Study at a glance
From the registry record, last updated by the sponsor on 30 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effects of the Scar Tissue Mobilization on Scar Thickness, Pliability and Quality of Life in Children With Upper Extremity Burns.
- ClinicalTrials.gov ID
- NCT07578883
- Acronym / sponsor ID
- REC/RCR&AHS/25/0713
- Conditions
- Burn Scar
- Keywords
- Scar tissue mobilization, Quality of life, Scar thickness, Pliability
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 15 participants (actual)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 14 Apr 2026 (actual)
- Primary completion
- 5 Jul 2026 (actual)
- Study completion
- 25 Jul 2026 (actual)
- First posted
- 11 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This quasi-experimental study evaluates the effect of scar tissue mobilization on scar thickness, pliability, and quality of life in children with upper extremity burns. Conducted at Mayo Hospital Lahore, children aged 8-13 will receive treatment for 5 weeks, with outcomes analyzed using SPSS 27.
Detailed description
Burn injuries, especially to the upper extremities, are common in children and can lead to hypertrophic scarring, resulting in pain, stiffness, and reduced range of motion. These complications significantly impact a child's ability to perform daily activities and affect overall quality of life and development. Rehabilitation plays a vital role in recovery, with scar tissue mobilization being a key intervention to improve scar flexibility and function. While commonly used, there is limited evidence on its specific effects in pediatric upper limb burns. This study aims to assess the impact of scar tissue mobilization on scar thickness, pliability and quality of life in children with upper extremity burns.
The study design will be Quasi experimental study. The data will be collected from mayo hospital, Lahore. The study will be completed in 10 months after the approval of synopsis. Children aged 8 to 13 years old will be included in this study and each patient will receive the same intervention. The participants will receive scar tissue mobilization intervention for 15 minutes twice a week for 5 weeks. Participants fulfilling the eligibility criteria will be asked to assign the consent form before entering into the study. The scar thickness and pliability will be measure from the Vancouver Scar Scale (VSS) and quality of life with Brisbane Scar Impact Profile (BBSIP). The synopsis will be presented to Research Ethical Committee of Riphah International University, Lahore for ethical approval to conduct this study. Data will be analyzed through SPSS 27.
Study design
- Primary purpose
- Other
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
- Model description
- Conducted as quasi experimental study, this study will include 15 pediatric burn patients aged 8-13, recruited from mayo hospital and Jinnah hospital Lahore. The participants receiving scar tissue mobilization. In this all patients receiving same intervention. Outcome measures, including scar thickness and pliability (via Vancouver scar scale), and quality of life (via Brisbane scar impact profile BBSIP). Statistical analysis will be performed using SPSS version 27 to determine the intervention effects.
| Arm | Type | Receives |
|---|---|---|
| Scar Tissue Mobilization on Scars and Quality of Life in Pediatric Upper Extremity Burns | Experimental | Other: Scar tissue mobilizationPatients received 15-minute massage sessions twice weekly for 5 weeks by the same therapist. Techniques included moderate-pressure strokes around wounds. |
Who may qualify
- Ages
- 8 to 13 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child
Key inclusion criteria (4 listed)
- 8-13 years
- Stable scar and referred for scar management
- Affected upper extremity joints (shoulder, elbow and wrist) with burned injuries
- Partial thickness and full thickness burn.
Key exclusion criteria (4 listed)
- Pre-existing skin condition or allergies
- Neurological disorders affecting motor function
- Fracture with burn in upper limbs
- Patient with only superficial burns
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Scar tissue mobilization15-minute massage twice weekly for 5 weeks using baby oil by the same therapist. Included moderate-pressure strokes, finger pressing, circular movements, skin rolling, and finishing gliding strokes. | Other | Scar Tissue Mobilization on Scars and Quality of Life in Pediatric Upper Extremity Burns |
Primary outcome
vancouver scar scale
Time frame: Baseline, 5 week
The Vancouver Scar Scale (VSS) is a widely used semi-quantitative tool for scar assessment that evaluates four parameters: vascularity, pigmentation, pliability, and height/thickness. It has a total score range of 0-13/14, where 0 indicates normal skin and higher scores represent more severe scarring, including thick scars and contractures.
Brisbane burn scar impact profile (BBSIP)
Time frame: Baseline, 5 week
A 40-item scale assessing children's quality of life across domains such as daily activities, hand function, appearance, psychological status, social relationships, and school activities. Items are scored from 0 (not at all) to 4 (a lot), with total scores classified as good (40-80), fair (80-100), and poor (>100). A 58-item burn scar-specific HRQoL self-report tool covering 10 domains including sensory, mobility, daily living, social interaction, appearance, and emotional reactions. Items use dichotomous, 11-point, or 5-point Likert scales; scores are calculated per domain, with lower scores indicating better quality of life.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Sep 2026.
- Background: PubMed 39548761Edger-Lacoursiere Z, Zhu M, Jean S, Marois-Page E, Nedelec B. Evidence Supporting Conservative Scar Management Interventions Following Burn Injury: A Review Article. J Burn Care Res. 2025 Aug 12;46(3):504-514. doi: 10.1093/jbcr/irae204.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Areej Saher, MS-PT principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Scar tissue mobilization in people with Burn Scar, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 30 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
vancouver scar scale (time frame: Baseline, 5 week). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT07578883, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Sep 2026.