Clinical trials: Burn Scar
Scar
Fractional Photothermolysis for the Treatment of Burn Scars
The aim of our study is to determine the effect of fractional photothermolysis laser in the treatment of burn scars.
- Trial name
- NCT01005992
- Testing
- Fractional laser treatment, Standard scar management
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Clinica las Condes, Chile
Burn, Hypertrophic Scar
Intron A for the Treatment of Hypertrophic Scar
This study assesses the intervention with antifibrotic agents, specifically interferon (IFN) to reduce the magnitude and duration of hypertrophic scar.
- Trial name
- NCT00686478
- Testing
- interferon alpha 2b
- Where
- Canada
- Sponsor
- University of Alberta
Hypertrophic Scar
Effect of Silicone Gel Versus Contractubex Phonophoresis for Post-burn Hypertrophic Scars
Hypertrophic scars and keloids are physically and mentally disturbed, and in addition, can cause pain and itching. Various treatment is utilized to diminish or counteract scarring.
- Trial name
- NCT03777891
- Testing
- phonophoresis with different material
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Cairo University
Burn Scar, Scar
Mechanistic Basis of Ablative Carbon Dioxide Laser in Treating Hypertrophic Scars
This is an observational cohort study which will look at the biomarkers from blood and tissue sample for adult patients with hypertrophic scarring due to burns/trauma incident over 12 months from date of recruitment.
- Trial name
- SMOOTH (NCT04736251)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Naiem Moiemen
Cryotherapy Effect, Burn Scar
Observation of the Comfort and Efficacy of CO2 Laser Combined With Cryo 6 for Burn or Linear Scars.
To investigate the effect of 10,600 nm CO2 laser combined with Zimmer Cryo 6 forced cold air device on the comfort and efficacy of patients with burn scars or post-operative linear scars, and to provide a safer, more effective…
- Conditions
- Cryotherapy Effect, Burn Scar, Scar; Previous Cesarean Section
- Trial name
- NCT05555602
- Testing
- Cold-air cooling
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kaiyang Lv, MD-PhD
Hypertrophic Scar
Use of Autologous Platelet-Rich Plasma to Treat Hypertrophic Burn Scars
Hypertrophic burn scars are experienced by more than 70% of burn victims. They are a major source of decreased quality of life in burn patients due to pain, decreased range of motion, and poor cosmetic appearance.
- Trial name
- NCT03935594
- Testing
- PRP Injection, Saline Injection
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Burn Injury, Acute Wound
Cutaneous Microcirculation After Plasma Therapy
In plastic and reconstructive surgery, treatment strategies of second-degree burns, superficial wounds, burn scars, flaps and chronic wounds aim at reducing infection and improving microcirculation.
- Conditions
- Burn Injury, Acute Wound, Chronic Wound, Burn Scar
- Trial name
- NCT02417818
- Testing
- Plasma Therapy (PlasmaDerm), Repetitive Plasma Therapy (repetitive PlasmaDerm)
- Where
- Germany
- Volunteers
- 240 people
- Sponsor
- University Hospital Schleswig-Holstein
Burns
Phase III Study With an Autologous Dermo-epidermal Skin Substitute for the Treatment of Burns in Adults and Adolescents
This multicentre phase III clinical trial will target adults and adolescents of 12 years and older with severe burns to confirm the efficacy and functionality of denovoSkin™ in achieving wound closure and reducing scarring in…
- Trial name
- NCT06745557
- Testing
- denovoSkin(TM), STSG
- Where
- 19 sites in Belgium, France and 7 more
- Volunteers
- 70 people
- Sponsor
- CUTISS AG
Burns Laser
Effects of Pressure Garments on Hypertrophic Hand Scar in Burn Children
Burns are type of injury that affect the skin or other tissues and are typically caused by acute trauma, including thermal sources, electricity, chemicals, friction, or radiation.
- Trial name
- NCT06198283
- Testing
- Low Level LASER Therapy with Pressure Garment, Low Level LASER Therapy without Pressure Garment
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Post-burn Innervation
Study of the Cutaneous Reinnervation After Burn
The aim of this study is to understand why the regeneration of the cutaneous sensory nerve fibers is poor in post-burn scar. The presence or the lack of several molecular factors known to regulate neuronal cell development will…
- Trial name
- NERVAL (NCT02356354)
- Testing
- Skin biopsy
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Brest
Scald Burn, Itching
Comparison of the Effects of Liquid Vaseline and Olive Oil on Itching and Scarring in Scald Burns
Pain, itching, hypertrophic scar formation after wound healing in burn patients complications, sleep disturbances in patients, anxiety, depression, and daily life It may disrupt activities and deterioration in quality of life.
- Conditions
- Scald Burn, Itching, Hypertrophic Scarring
- Trial name
- NCT06104540
- Testing
- Experimental I liquid vaseline groups, Experimental II extra virgin olive oil groups, Control Croup
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Burns Scarring
Carbon Dioxide Laser Treatment in Burn-related Scarring
This study evaluates the effect effect of ablative fractional CO2 laser (AFCO2L) on burns scar appearance and dermal architecture at 6 weeks and up to 3-years post-treatment.
- Trial name
- NCT03433664
- Testing
- CO2 laser
- Volunteers
- 19 people
- Sponsor
- The University of Western Australia
Burns, Burn Scar
Evaluation of Physical Functions in Lower Limb Burn Injury
This study evaluates scar tissue, normal range of motion of lowr extremity joints, lower extremity functions, functional capacity, functional mobility, kinesiophobia and quality of life in lower limb burn injury.
- Conditions
- Burns, Burn Scar, Lower Limb Injury, Lower Limb Wound
- Trial name
- NCT04157504
- Testing
- Physical function assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Burn Scar
Nonsilicone Gel Sheet for Burn Hypertrophic Scars
Overview: The application of gel sheets holds promise for both the prevention and treatment of hypertrophic scar after deep dermal injuries.
- Trial name
- NCT05429411
- Testing
- Silicone gel
- Where
- Canada
- Volunteers
- 49 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Cicatrix
Observational Study for the Long-Term Effects of a Dermal Substitute on Patients With Facial Burns.
The aim of this observational study is to investigate the long-term (between 10-20 years) results for the surgical treatment of third degree burn injury in the face and/or the neck by means of Integra® Dermal Regeneration…
- Trial name
- NCT03971968
- Testing
- Skin replacement with artificial skin
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- Universitair Ziekenhuis Brussel
Scars, Hypopigmented Scar
Treatment of Hypopigmented Scars With Bimatoprost
Patients who have hypo-pigmented burn scar will have two scars chosen and randomized to treated scar and control scar. The subject will then have both scars treated with fractional ablative CO2 laser (FLSR).
- Conditions
- Scars, Hypopigmented Scar, Hypopigmented Skin, Burn Scar
- Trial name
- NCT06122090
- Testing
- Bimatoprost, Saline
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medstar Health Research Institute
Hand-burned Children
Comparative Study Between Botulinum Toxin-A Injection and Shock Waves on Hypertrophic Scars in Hand-burned Children
PURPOSE: The study aims to compare study between Botulinum toxin-A injection and shock waves therapy on hypertrophic scars in hand-burned children.
- Trial name
- NCT06174155
- Testing
- physical therapy treatment, Botulinum toxin-A injection in addition to physical therapy program, shock wave therapy in addition to physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Burn Scar
Scar Management Through Serial Casting
Scar management remains one of the major clinical challenges for burn survivors with hypertrophic scars. Beyond their visible appearance, hypertrophic scars can significantly impair physical function, reduce life satisfaction…
- Trial name
- NCT07645664
- Testing
- Serial casted scar
- Volunteers
- 38 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Joint Contracture, Contracture
Recurrence of Extremity Joint Contracture After Z-Plasty Versus Full-Thickness Skin Graft
The purpose of this study is to compare how often joint contractures in the arms and legs come back after two common types of reconstructive surgery: Z-plasty and full-thickness skin graft (FTSG).
- Conditions
- Joint Contracture, Contracture, Cicatrix, Burn Scar Contractures
- Trial name
- NCT07885046
- Testing
- Z-Plasty, Full-Thickness Skin Graft
- Volunteers
- 300 people
- Sponsor
- Universitas Sebelas Maret
Burn Scar, Scalp Wound
Easy Way of Choosing Rectangular Expander and Getting Maximum Benefit From Expanded Tissue
Background: Tissue expanders are widely used for reconstruction of tissue defects. The choice of expander and planning the flap is complicated for the inexperienced surgeon.
- Trial name
- NCT03544697
- Testing
- Skin expansion and repair with flaps
- Volunteers
- 19 people
- Sponsor
- Izmir Katip Celebi University