HeadacheNCT07587398
The Effectiveness of Acupuncture on Headaches in Women Undergoing IVF Egg Stimulation
A study testing Acupuncture in people with Headache and Stress (Psychology), run by Yo San University of Traditional Chinese Medicine at 1 site in United States.
Trial summary
To test the effect of acupuncture in treating headaches, as well as co-measures of stress and emotional distress, in participants during the hormonal stimulation phase prior to an oocyte retrieval. Read more about this study
- Who is it for?
- Ages 29 to 49 years, women only
- Conditions the study is for
- Headache, Stress (Psychology), Emotional Distress
- What is being tested?
- Acupuncture
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 37 participants
- Where
- 1 siteUnited States
- Study dates
- 27 Feb 2023to 1 Aug 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 29 to 49 years
- Women only
- No healthy volunteers
- Adult
Who may be able to join
- adult biological female
- participating in an active hormone stimulation cycle
- receiving acupuncture treatment for fertility support at SCRC in Beverly Hills with the second investigator
- experiencing a headache
Who cannot join
- participants undergoing a medicated IUI
Trial locations and contacts
1 site in 1 country.
United States1 site
Southern California Reproductive Center
Beverly Hills, California, 90210
About this study
Official title: The Effectiveness of Acupuncture on Headaches in Women Undergoing IVF Egg Stimulation: A Pilot Pre-Post Observational Study
To test the effect of acupuncture in treating headaches, as well as co-measures of stress and emotional distress, in participants during the hormonal stimulation phase prior to an oocyte retrieval. Subjects were identified females at birth experiencing a headache while undergoing a hormone stimulation cycle as part of in vitro fertilization or oocyte cryopreservation. Intervention was an individualized acupuncture treatment with needle retention for thirty minutes. Main outcome measured were headache intensity, level of stress, level of emotional distress.
- Conditions
- Headache, Stress (Psychology), Emotional Distress
- Being tested
- Acupuncture
- Keywords
- Acupuncture, Headache, IVF, Stress, Egg Stimulation
- Medical subject headings
- Headache
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
AcupunctureProcedure or surgery
Acupuncture treatment with 30 minute needle retention
| Study group | Role | What they receive |
|---|---|---|
| Acupuncture | Experimental | Acupuncture treatment with 30 minute needle retention Receives: Procedure: Acupuncture |
What is being measured
The primary outcome is the main question the study is designed to answer.
Headache Intensity
Level of headache intensity scored on a scale of 0-10
Measured: Change from before intervention to after intervention for any number of acupuncture treatments over the length of a stimulation cycle (about 2 weeks)
Secondary outcomes (2)
Stress
Level of stress reported by the participant scored on a scale of 0-10 with 0 being defined as "no stress" and 10 being defined as "the highest possible stress"
Measured: Change from before intervention to after intervention for any number of acupuncture treatments over the length of a stimulation cycle (about 2 weeks)
Emotional Distress
Level of emotional distress reported by the participant scored on a scale of 0-10 with 0 being defined as "no stress" and 10 being defined as "the highest possible stress"
Measured: Change from before intervention to after intervention for any number of acupuncture treatments over the length of a stimulation cycle (about 2 weeks)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 May 2026
- Study start27 Feb 2023
- Primary completion22 Jul 2024
- Study completion1 Aug 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HeadacheStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 37 participants (actual)
Sponsor and investigators
- Lead sponsor
- Yo San University of Traditional Chinese Medicine
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07587398
- Sponsor's protocol ID
- 20230222C12
- Status last verified
- May 2026
- First submitted
- 30 Apr 2026
- Last updated
- 14 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 14 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effectiveness of Acupuncture on Headaches in Women Undergoing IVF Egg Stimulation: A Pilot Pre-Post Observational Study
- ClinicalTrials.gov ID
- NCT07587398
- Acronym / sponsor ID
- 20230222C12
- Conditions
- Headache, Stress (Psychology), Emotional Distress
- Keywords
- Acupuncture, Headache, IVF, Stress, Egg Stimulation
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 37 participants (actual)
- Lead sponsor
- Yo San University of Traditional Chinese MedicineUniversity, hospital or other
- Study start
- 27 Feb 2023 (actual)
- Primary completion
- 22 Jul 2024 (actual)
- Study completion
- 1 Aug 2024 (actual)
- First posted
- 14 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
To test the effect of acupuncture in treating headaches, as well as co-measures of stress and emotional distress, in participants during the hormonal stimulation phase prior to an oocyte retrieval. Subjects were identified females at birth experiencing a headache while undergoing a hormone stimulation cycle as part of in vitro fertilization or oocyte cryopreservation. Intervention was an individualized acupuncture treatment with needle retention for thirty minutes. Main outcome measured were headache intensity, level of stress, level of emotional distress.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Acupuncture | Experimental | Procedure: AcupunctureAcupuncture treatment with 30 minute needle retention |
Who may qualify
- Ages
- 29 to 49 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- adult biological female
- participating in an active hormone stimulation cycle
- receiving acupuncture treatment for fertility support at SCRC in Beverly Hills with the second investigator
- experiencing a headache
Key exclusion criteria (1 listed)
- participants undergoing a medicated IUI
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| AcupunctureAcupuncture treatment with 30 minute needle retention | Procedure or surgery | Acupuncture |
Primary outcome
Headache Intensity
Time frame: Change from before intervention to after intervention for any number of acupuncture treatments over the length of a stimulation cycle (about 2 weeks)
Level of headache intensity scored on a scale of 0-10
2 secondary outcomes
Stress
Time frame: Change from before intervention to after intervention for any number of acupuncture treatments over the length of a stimulation cycle (about 2 weeks)
Emotional Distress
Time frame: Change from before intervention to after intervention for any number of acupuncture treatments over the length of a stimulation cycle (about 2 weeks)
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 May 2026.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Acupuncture in people with Headache and Stress (Psychology), run by Yo San University of Traditional Chinese Medicine at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 14 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Headache Intensity (time frame: Change from before intervention to after intervention for any number of acupuncture treatments over the length of a stimulation cycle (about 2 weeks)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 May 2026.